Articles tagged with Insulin
A team of Type 1 diabetic athletes, including University of North Carolina M.D.-Ph.D. candidate Jeremy Ackerman, will climb Cerro Aconcagua in Argentina to raise awareness about diabetes and conduct scientific research on the effects of altitude on diabetics.
Insulin reduces expression of molecule promoting inflammation and clogging of arteries, increasing production of vasodilator nitric oxide. The study's findings indicate insulin may have an antiatherosclerotic role, potentially protecting people at risk of CVD.
A diagnostic test allows physicians to identify a rare, severe imbalance of insulin levels in newborns, which can be cured with organ-sparing surgery. The test differentiates between diffuse and focal forms of congenital hyperinsulinism (HI), enabling targeted treatment.
Researchers found that Avandia had a lower rate of elevated alanine aminotransferase (ALT) levels compared to placebo and other treatments. This suggests that Avandia is a valuable option for patients with type 2 diabetes, as it can help improve blood sugar control and potentially slow disease progression.
UCSD School of Medicine scientists have successfully cultured human beta cells that can produce insulin indefinitely. The immortal cell line holds promise for treating people with diabetes through transplantation, potentially offering an unlimited source of insulin-producing tissue.
Research suggests that honey is an effective form of carbohydrate gel for athletes, providing a sustained energy boost without causing a rapid spike in blood sugar levels. The study found that honey's lower glycemic index profile makes it an ideal choice for pre-workout consumption, potentially improving endurance and reducing fatigue.
Weizmann Institute researchers find a family of amino acid analogues that effectively regulate glucose levels in diabetic laboratory animals. The new compounds have greater antidiabetic potency than vanadium alone, offering a promising treatment option for type II diabetes.
Researchers at the University of Illinois have isolated and characterized an insulin gene from the marine mollusk Aplysia californica. The study reveals a unique peptide, the 'D' peptide, which is separated from the standard two-chain insulin structure by a 'C' peptide.
Rosiglitazone reduces insulin resistance by 33% and improves pancreatic function in individuals with type 2 diabetes. The treatment also reduces insulin levels in the blood, potentially alleviating the need for regular insulin injections.
Researchers at the University of Delaware have developed a mathematical algorithm that can precisely control blood-sugar levels in people with Type I diabetes using an implantable insulin pump. The chip-based system predicts insulin needs based on glucose sensor data, reducing peak glucose levels by 44% and overshoot by 80%.
Scientists have identified a compound that mimics the effects of insulin in mice, offering hope for a pill-based treatment for diabetes. The new substance, L-783,281, is a nonpeptide molecule that can be absorbed through the bloodstream after being swallowed, potentially providing an alternative to insulin injections.
A new study reveals that adult-onset diabetics may be suffering from an 'imbalancing act' caused by a key enzyme called PFK, which regulates glucose metabolism. The researchers found that mice with abnormally high levels of the PFK-L sub-unit developed symptoms of Type II diabetes.
Researchers at Purdue University have developed an oral delivery method for insulin that may eventually treat human diabetes. The method uses a gel-like material to protect insulin from stomach enzymes, allowing it to release the drug in a location where it can work.
A new oral vaccine approach is being developed to protect pancreatic cells and prevent the autoimmune disease type I diabetes. Early trials have shown promising results using a combination of insulin and cholera toxin.
A graduate student at Purdue University has developed a gel-like material that expands and contracts in response to changes in acidity, mimicking the natural response of the body. The gel could be used as a 'molecular gate' to deliver insulin in real-time, responding to glucose levels.
Researchers at Duke University found that pre-treating insulin-producing pancreatic islet cells with glutathione preserves their ability to regulate sugar levels. This advance could overcome a major hurdle in the transplantation of islet cells into humans as a treatment for diabetes.
Brown University researchers have developed a novel oral drug delivery system using erodible plastic microspheres that can improve the efficacy of drugs like insulin. The microspheres, engineered with bioadhesive polymers, increase absorption rates and enhance therapeutic effects.
Researchers studied 171 hospital patients with diabetes mellitus and found that sliding scale insulin regimens provided no benefit. Patients on standing regimens fared better than those on sliding scale regimens, which tripled the risk of hyperglycemia when used alone.
A year-long study found that implantable insulin pumps effectively controlled blood glucose levels, reduced fluctuations in blood glucose, and mild hypoglycemia by 68% compared to daily injections. The pump also eliminated weight gain associated with injections and improved patients' quality of life.
UT Southwestern Medical Center is part of a nationwide clinical study to test an oral insulin capsule on people at moderate risk for developing type I diabetes. The study aims to determine if the intervention can prevent or delay the disease.