Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
A study tracking over 3600 participants found that maternal factors and depression/anxiety were significant predictors of adolescent sleep problems. Conversely, an active lifestyle was found to decrease future incidence of sleep problems.
A study found that Mexican-Americans living in the US have more risk factors for liver cancer, including obesity and diabetes, compared to those in Mexico. The study's lead author notes that having multiple risk factors increases the likelihood of developing liver cancer.
A 45-year-old woman developed a rare but life-threatening condition called fat embolism syndrome (FES) after undergoing liposuction. FES is notoriously difficult to diagnose due to a lack of standardized diagnostic criteria, emphasizing the need for clinicians to think outside the box and consider alternative diagnoses.
A recent analysis found that there are only six studies with empirical data on factors associated with terrorism, and most have variable quality. The lack of research in this area underscores the importance of addressing it to inform national security.
A leading neuroscientist has developed an innovative program to treat Alzheimer's disease with a novel N-of-1 design that individualizes medicine for each patient. The approach aims to identify person-specific risk factors and apply customized interventions to prevent dementia.
A recent study found that women with coronary heart disease are less likely to achieve treatment targets than men. Women were more likely to have better control of blood pressure and be non-smokers, but struggled with cholesterol levels, physical activity, and obesity.
Researchers at Joslin Diabetes Center identified PKC-delta as a natural protective factor that works against chronic inflammation in diabetes, which can lead to cardiovascular disease. The study found that PKC-delta suppresses the population of macrophages and inhibits a biological pathway that protects cells from dying.
A recent study reveals that transgender patients with diabetes often experience increased modifiable risks, including high triglycerides and LDL cholesterol levels. The researchers emphasize the need for improved diabetes care and specialist support to prevent cardiovascular disease and other complications.
A study published in Diabetologia found approximately 1.8 million US adults aged 40+ with diabetes, CKD, and diabetic retinopathy, indicating a significant risk of CKD progression and death. The presence of DR is a reliable screening tool for identifying individuals at high risk.
A study published in Annals of Internal Medicine found that excessive sedentary time, regardless of exercise habits, significantly increases the risk of death. Taking regular movement breaks can help mitigate this effect.
A new paper defines 50 term pairs in psychology, including envy/jealousy and disease/illness, to improve psychological literacy. The list helps distinguish between related concepts, such as punishment vs. negative reinforcement, antisocial vs. asocial behavior.
A new study from Uppsala University finds that genetic effects on obesity are not fixed but interact with lifestyle factors. The study reveals that physical activity and socio-economic status can reduce the impact of genes on weight.
Chinese children who go to bed later and sleep less are more likely to be overweight, with each hour later bedtime increasing BMI scores. The study suggests cultural factors, such as emphasis on studying and academic achievement, contribute to shorter sleep durations.
The US Preventive Services Task Force (USPSTF) recommends vision screening for children aged 3-5 to detect amblyopia. However, the evidence for this age group is considered moderate, while it is insufficient for children under 3 years old. Early detection of vision abnormalities can prevent permanent vision loss in affected eyes.
A Penn-led study identified 16 new genes associated with type-2 diabetes and one new genetic risk factor for coronary heart disease. The researchers found that most of the sites known to be associated with higher diabetes risk are also linked to higher CHD risk, highlighting potential targets for future therapies.
Researchers found a strong biological link between Epstein-Barr virus and multiple sclerosis (MS) across three racial groups. The study found that blacks, Hispanics, and whites who had mononucleosis were more than two to nearly four times more likely to develop MS than those who did not.
A new study published in JAMA Neurology analyzed 27 research studies and found that female carriers of the apolipoprotein E ?4 allele have a greater risk of developing Alzheimer disease, particularly between ages 65-75. The authors suggest physiologic changes associated with menopause and estrogen loss may underlie these sex differences.
Researchers found that married patients who have had a heart attack are 14% more likely to survive compared to single patients. Marriage also provides protection for patients with high cholesterol, diabetes, and high blood pressure, increasing their chances of survival by 16%, 14%, and 10%, respectively.
A 16-year study of over 280,000 patients found that colder air temperatures are associated with a higher risk of heart attacks. The study, led by Prof David Erlinge from Lund University, used meteorological data to analyze the relationship between weather conditions and heart attack incidence.
The RACE 3 trial found that risk factor-driven upstream rhythm control is effective in improving maintenance of sinus rhythm in patients with early short-lasting AF and heart failure. Sinus rhythm was present in 75% of patients in the upstream therapy group compared to 63% in the control group.
Researchers review neuroinflammation as a key factor in Alzheimer's and Parkinson's diseases, highlighting four modifiable risk factors: physical inactivity, vascular disease-related conditions, obesity, and type two diabetes mellitus. Controlling these risk factors may help manage the increasing incidence of both diseases.
A recent study found that current smoking in older people increases the risk of developing frailty. Frailty is a condition associated with decreased physiological reserve and increased vulnerability to adverse health outcomes.
A national survey of pubic hair grooming habits found that 76.1% of participants reported a history of grooming, with 25.6% experiencing injuries such as cuts, burns, and rashes. The study's findings may contribute to the development of clinical guidelines for safe pubic hair removal.
New research finds that binge-viewing TV shows can negatively impact sleep quality in young adults, leading to increased fatigue and insomnia. The study suggests that the intense engagement with content before bedtime causes mental arousal, disrupting sleep patterns.
A recent Harvard University study reveals that knee osteoarthritis has dramatically increased in prevalence over the past 70 years, affecting an estimated one-third of Americans over 60. The research challenges the long-held assumption that osteoarthritis is simply a wear-and-tear disease related to aging and obesity.
Researchers found knee OA in 16% of postindustrial individuals 50+, but only 6% and 8% in early industrial and prehistoric samples. The findings suggest an approximate doubling of knee OA prevalence since the mid-20th century.
A new study published in Arthritis Care & Research found that male workers in the manufacturing sector have a higher risk of developing rheumatoid arthritis than those in other sectors. Women working in certain occupations, such as assistant nurses and attendants, also showed a slightly increased risk of rheumatoid arthritis.
A study published in JAMA Surgery found that women with a history of C-section delivery had a higher risk of reoperation and surgical complications after undergoing a hysterectomy. Women with two or more C-section deliveries were also more likely to receive blood transfusions.
Research found that socioeconomically disadvantaged children are more likely to have thicker carotid artery walls, indicating a higher risk for heart attack and stroke. The study suggests that infection and inflammation may be underlying factors driving this association.
A large NIH-funded study found that middle-aged Americans with vascular health risk factors such as diabetes and high blood pressure are more likely to develop dementia later in life. The study analyzed data from 15,744 participants over 25 years and found a strong link between midlife vascular health and the risk of developing dementia.
A new study finds that depression in heart patients significantly increases the risk of death, with depressed heart patients having twice the risk as non-depressed heart patients. The study emphasizes the importance of continued screening for depression in all heart disease patients.
Research suggests that individuals with a family history of bipolar disorder may experience faster biological aging. The study found that patients treated with lithium had longer telomeres, which could help reverse age-related changes. This association may explain the higher rates of aging-related diseases among bipolar disorder patients.
A study found that kidney transplant recipients have a higher incidence of melanoma compared to the general population, with risk factors including older age, male sex, and white ethnicity. Long-term immunosuppressive therapy contributes to this increased risk.
A recent study found that men with hepatitis B are more than twice as likely to develop severe liver disease as women, even when accounting for lifestyle and environmental factors. Drinking alcohol significantly increases liver disease risk in both men and women, but sex remains the strongest indicator of liver disease severity.
The American Academy of Pediatrics recommends focusing on clusters of cardiometabolic risk factors, such as high blood sugar, hypertension, and obesity, to identify overweight or obese children at highest risk for cardiovascular and metabolic complications. Pediatricians should target youth with multiple component risk factors for more...
New narrative review calls for additional research to better understand cardiovascular disease (CVD) and risk factors in transgender individuals receiving long-term cross-sex hormone therapy. Studies suggest worsening cardiovascular risk factors in transgender men and increased thromboembolic risk in transgender women.
A new map of brain protein interactions could lead to more effective treatments for complex brain disorders like autism and schizophrenia. The map, created by USC researcher Marcelo P. Coba, highlights problematic pathways that current drugs are not targeting.
A recent survey of primary care physicians found that nearly two-thirds could not correctly identify all risk factors for prediabetes. The study highlights the need for increased provider knowledge and availability of resources to help patients reduce their risk of developing type 2 diabetes.
A study examining MLB pitchers over six seasons found that decreased shoulder flexion and external rotation were key predictors of elbow injuries. The risk of injury increased with greater than five-degree flexion deficits and external rotation deficits.
A new report models the impact of nine risk factors on dementia, including education, hearing loss, and smoking, and estimates that removing these factors could prevent 35% of all dementia cases. Increasing education in early life, reducing hearing loss, and stopping smoking are identified as key interventions.
Women with early or normal onset menopause are at a higher risk of developing type 2 diabetes than those with late onset menopause. The study found that women who experienced menopause before age 40 were almost 4 times more likely to develop T2D.
Cox was recognized for his 1972 paper on the proportional hazards model, widely used in survival data analysis. The model has been applied to various fields, leading to life-changing breakthroughs and societal impact.
A study of 930 older adults found that non-elective hospitalizations accelerated cognitive decline by 60%, while elective hospitalizations had no association. Researchers highlight the need for attention on hospitalization as a risk factor for dementia and cognitive decline in older adults.
Researchers will use PET scans and MRI to detect harmful chemical build-up and measure brain structure, with a focus on 40-65 year olds. The project hopes to develop ways to intervene before irreversible damage is done.
A study published in the European Heart Journal found that people who work long hours (55+ hours/week) are approximately 40% more likely to develop atrial fibrillation over a ten-year period. The risk is higher among those with pre-existing cardiovascular disease and other risk factors.
Research reveals black adults are twice as likely to experience fatal first cardiac events compared to whites. The study suggests social determinants of health and cardiovascular risk factors contribute to this disparity.
A recent study found that psychosocial factors such as depression and anxiety disorders have a stronger negative impact on subjective well-being in older adults. The researchers analyzed data from over 3,600 participants aged 73 and found that women living alone were more likely to experience low well-being.
A new report finds that nearly half of all cancer deaths in China are attributable to potentially modifiable risk factors. The study reveals that effective public health interventions can have a significant impact on reducing the cancer burden in China.
A recent study found that elderly patients who visit emergency departments due to falls are at risk for adverse events, including additional falls, hospitalization, and death within 6 months. The study highlights the importance of educating patients on how to prevent falls after discharge from the emergency department.
A large-scale study found that higher body mass index (BMI) is associated with an increased risk of coronary heart disease, hypertension, and type 2 diabetes. The study, which included over 119,000 participants, also showed that higher BMI was linked to higher systolic and diastolic blood pressure.
A longitudinal study found that overweight, high blood pressure, and low-density lipoprotein cholesterol in childhood are linked to decreased arterial distensibility in adolescence. The study suggests that primordial prevention of cardiovascular diseases should focus on children and young people.
A Stanford study found that sleep disturbances in young adults can warn of worsening suicidal thoughts, even when controlling for depression severity. Participants with varying sleep patterns reported more insomnia and nightmares, which independently predicted increased suicidal behaviors.
A new analysis shows that genetic variation and elevated ozone exposure increase the risk of developing autism, with an added effect when combined. The study found that copy-number variation and particulate matter in the environment had significant individual impacts on autism risk.
Newly diagnosed asymptomatic atrial fibrillation patients have a higher rate of previous stroke compared to those with symptoms. The study found that patients with non-valvular atrial fibrillation have a five-fold increased risk of stroke, and strokes in these patients tend to be severe and disabling.
Shared decision-making between patients and healthcare providers is essential for optimal MS treatment and quality of life. The process involves working together to select tests, treatments, and care plans, taking into account evidence-based treatments and lifestyle factors.
Research suggests that anti-Muslim sentiment can promote discrimination, limiting Muslim communities' social resources and social cohesion, which may lead to radicalization. Promoting community capacity building could be an effective strategy to improve health and limit radicalization.
A new study found that older adults are less likely to leave the hospital against medical advice than younger individuals, with men and people insured by Medicaid or without health insurance at highest risk. Factors such as race/ethnicity, poverty, and suboptimal communication play a role in this phenomenon.
Researchers analyzed national health statistics to understand demographic differences in diabetes rates and care sought. The study found that people with lower income or lower educational levels had a higher prevalence of diabetes, with American Indians and Alaska Natives having the highest rates.
A new USC study found that a poor diet, combined with the ApoE4 gene variant, can increase the development of Alzheimer's plaques in mice. The study suggests that lifestyle factors such as diet and exercise may play a role in regulating the risk of Alzheimer's disease.
A study of 13,948 participants found that lower education levels were associated with increased lifetime risks of coronary heart disease, heart failure, and stroke. Higher education levels resulted in lower CVD risk, regardless of other socioeconomic factors.