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Study finds following a healthy lifestyle can greatly reduce genetic heart attack risk

A study led by Massachusetts General Hospital found that following a healthy lifestyle can significantly reduce genetic heart attack risk. The research team analyzed data from over 55,000 participants and found that each healthy lifestyle factor reduced risk, with favorable lifestyles cutting incidence by 50% in those at highest geneti...

SourceMassachusetts General Hospital·JournalNew England Journal of Medicine·DateNov 13, 2016

Knowing risk factors could help catch melanomas

A study published in JAMA Dermatology found that patients with a family history of melanoma, multiple primary melanomas, or many moles are at higher risk for developing melanoma. The researchers recommend tailoring surveillance programs to individual risk factors to improve early detection and treatment.

SourceUniversity of Sydney·JournalJAMA Dermatology·DateNov 9, 2016

Targeting cardiovascular disease risk factors may be important across a lifetime

A recent NIH-funded study found that all adults, regardless of age, should be mindful of risk factors for cardiovascular disease. The study, led by George Howard, discovered that nearly half of participants developed high blood pressure during a 10-year follow-up, highlighting the importance of prevention efforts across the lifespan.

SourceNIH/National Institute of Neurological Disorders and Stroke·JournalJournal of the American Geriatrics Society·DateOct 5, 2016

Study examines risk, risk factors for depression after stroke

A study of over 135,000 patients with stroke found that the risk of depression within two years was eight times higher than in a reference population, with half of cases appearing in the first three months after stroke. Major risk factors for depression included older age, female sex, and history of depression or severe stroke.

SourceJAMA Network·JournalJAMA Psychiatry·DateSep 7, 2016

Five-year study reveals patients operated on at night twice as likely to die as patients who have daytime operations

A five-year study found that patients operated on at night are twice as likely to die compared to those who have surgery during regular working hours. The study also revealed that late-day surgeries carry a higher mortality risk, with patients in these situations 1.43 times more likely to die than those undergoing daytime operations.

Dartmouth Institute-led team developing universal toolkit to predict hospital readmission risk

A Dartmouth Institute-led team is developing a universal electronic medical record (EMR) toolkit to predict hospital readmission risk. The toolkit will integrate with existing EMRs to monitor and measure risk of readmission, focusing on patients at highest risk, particularly those hospitalized for acute myocardial infarction (AMI).

Genetic and environmental risk factors for chronic pain

A new study found that genetic factors account for 38.4% of the variation in chronic pain risk, while shared environment with spouses contributes to 18.7%. The research also discovered a correlation between chronic pain and depression, highlighting the importance of identifying shared causal mechanisms.

SourcePLOS·JournalPLOS Medicine·DateAug 16, 2016

High fat diet improves cartilage repair in mice

A high fat diet and increased body weight do not impair but may even accelerate cartilage repair in a mouse model. The study's findings suggest that the mechanism behind this phenomenon is related to inflammatory and metabolic changes.

SourceWiley·JournalJournal of Orthopaedic Research®·DateJul 19, 2016