A study published in Annals of Behavioral Medicine found that experiencing social stressors during adolescence and young adulthood can lead to increased disease risk factors in middle age. The researchers analyzed data from 822 participants and discovered a significant link between early adversity and allostatic load, a measure of phys...
Researchers have identified a dozen genetic modifiers of amyloid beta toxicity in yeast, including several linked to Alzheimer's disease risk by genome-wide association studies. The yeast model also showed that these genes can suppress Aβ-induced neuronal loss in worms and cultured rat neurons.
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A study found that patients with certain genetic variants related to clopidogrel metabolism and platelet function are at higher risk of developing blood clots within coronary stents. The researchers identified three key genetic factors and two modifiable clinical factors that increase the risk of early stent thrombosis
A study has discovered four gene variants that contribute to early stent thrombosis in people with coronary artery disease. These variants affect blood thinner clopidogrel sensitivity and platelet receptor function, increasing the risk of deadly complications after stent implantation.
A recent study published in Investigative Ophthalmology & Visual Science found a strong association between physical fitness and reduced glaucoma risk. The research discovered that moderate physical activity can lower the risk of low ocular perfusion pressure, a key factor in glaucoma development.
A recent study has identified a potential link between human papillomavirus (HPV) and cardiovascular disease (CVD) in women. The research, published in the Journal of the American College of Cardiology, found that cancer-causing strains of HPV were strongly associated with CVD, even after adjusting for other risk factors.
A new study published in Canadian Medical Association Journal found daily smoking and low mastery to be significant risk factors for repeat episodes of depression. High levels of mastery appeared to be protective against further depression.
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A study by Dr. Joan Tranmer found that female hospital staff working night shifts are at a higher risk of developing metabolic syndrome, high blood pressure, and abdominal obesity. The study suggests that age and shift work status are significantly associated with increased risk.
Research from the European Prospective Investigation into Cancer and Nutrition (EPIC) study found that 47.6% of hepatocellular carcinoma cases were associated with smoking, while chronic hepatitis B and C infection was the strongest risk factor. The study also highlights the importance of quitting smoking to reduce liver cancer risk.
A new study by Oregon State University found that men experiencing persistently moderate to high levels of stressful life events have a 50% higher mortality rate. The study, which documented patterns of stress over 18 years, identified protective factors such as good health and moderate drinking habits.
A study of nearly 20,000 patients found that low values in three medical measures - median arterial pressure, median anesthetic concentration, and bispectral index - correlate with increased mortality risk. The triple-low combination was associated with a 2.5-times higher risk of death during the first year after surgery.
A systematic review of 26 validated readmission risk prediction models found most models have poor predictive ability for both clinical and administrative use. The review suggests that only a few models can accurately identify high-risk patients for early intervention.
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A study suggests that punitive damages should be calculated based on a company's financial worth to effectively deter corporate wrongdoing. Research highlights cases where increased penalties led to behavioral changes, such as BMW's policy shift after being forced to pay $4 million in punitive damages.
Women with polycystic ovary syndrome (PCOS) are at a higher risk for cardiovascular disease, with increased triglycerides and insulin resistance contributing to the condition. Regular screening and treatment can help mitigate this risk, but more research is needed to understand the extent of PCOS's impact on cardiovascular health.
Research finds UK doctors are underdiagnosing and undertreating atrial fibrillation, a major risk factor for stroke, despite improvements in stroke prevention. The study analyzed data from the General Practice Research Database and found that only one in four patients with AF were prescribed preventive anticoagulant treatment.
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A recent study found that children under 3 with a nasolacrimal duct obstruction are at increased risk for developing amblyopia, with an 8-fold increase compared to the general population. Early treatment is crucial, as poor vision becomes permanent if left untreated.
Researchers have analyzed and ranked various risk factors for open angle glaucoma to enable earlier screening. The study found that certain factors such as age, smoking history, visual field test results, and Cup-to-Disk ratio significantly increase the risk of developing OAG.
A study by the University of Manitoba and the Manitoba Metis Federation found a 25% higher stroke rate among Metis compared to other Manitobans. The research identified a link between Metis-specific health issues, such as smoking, diabetes, and high blood pressure, which increase stroke risk.
A recent study by Lawson Research Institute found that nearly half of newly diagnosed Canadian patients with glaucoma were at moderate to advanced stages by the time of diagnosis. The study suggests a lack of preventive screenings and inadequate awareness about risk factors are contributing factors to this issue.
Researchers at UCLA developed a risk scoring system to predict long-term survival after liver re-transplantation, identifying eight key risk factors for potential failure. The predictive index will help guide physicians in determining patient risk and provide patients with informed consent information.
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A recent study found that most feline intestinal cancers are lymphoma and tend to occur in the small intestines. The researchers also identified a higher risk of intestinal cancer in Siamese breed males over seven years old.
Native American communities have the highest alcohol-related death rates, but how and why this is prevalent remains unclear. The new five-year MERIT award will investigate early underage drinking's impact on risk for alcoholism and develop culturally relevant treatment programs.
Researchers found that cardiac rehabilitation programs significantly improved patients' risk profiles after a transient ischemic attack (TIA) or mild stroke. Patients showed improvements in cholesterol levels, body mass index, waist circumference, and blood pressure.
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A Finnish study published in PLoS Medicine found that people living alone are more vulnerable to the adverse effects of increased alcohol availability, leading to a substantially increased risk of alcohol-related mortality. The study analyzed data from over 80% of Finland's population between 2000 and 2007 and discovered a greater incr...
A recent study found that older patient age, congestive heart failure, and preoperative neurological problems are independent risk factors for death and complications after spine surgery. The study analyzed data from the American College of Surgeons National Surgical Quality Improvement Program database.
A recent study published in Neurology found that people with diabetes are twice as likely to develop dementia as those with normal blood sugar levels. The study, which monitored over 1,000 participants for an average of 11 years, also found that controlling diabetes is crucial to prevent cognitive decline.
A new study published in Autism Research found that parental age, maternal ethnicity, and paternal age are associated with an increased risk of autism spectrum disorders (ASD) and intellectual disabilities (ID), while household income has no significant link. The research also identified demographic risk factors such as male gender and...
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A study introduces ethnicity-specific reference genome sequences to analyze whole-genome sequencing data, improving disease risk assessment. The approach was demonstrated in a four-person family and showed increased accuracy in detecting rare variants and reducing errors.
Researchers at Wake Forest Baptist Medical Center found no association between sickle cell trait and risk of non-diabetic or diabetic end-stage kidney disease. The study contradicts earlier findings that suggested having one copy of the sickle cell gene increased kidney disease risk.
A meta-analysis of six randomized controlled trials found that treating cardiovascular risk factors improves sexual function in men with erectile dysfunction, even when lifestyle interventions alone were used. The study suggests that addressing CV risk factors can have a positive impact on ED and overall quality of life.
The C-CHANGE guidelines integrate over 400 recommendations into one comprehensive resource, distilling practice and evidence down to 89 simplified recommendations. This harmonization aims to improve health outcomes by promoting a more evidence-based approach to cardiovascular care.
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According to a Canadian Medical Association Journal study, approximately 19% of Canadians have metabolic syndrome. The syndrome is more common among people with lower income and education levels, particularly those with abdominal obesity.
A three-year study will investigate the psychological factors associated with suicide among LGBT youth, including thwarted belongingness and perceived burdensomeness. The research aims to identify risk factors and develop preventive messaging and interventions to reduce suicidal behaviors.
Researchers found that the body's internal clock regulates human platelet function, causing a peak in platelet activation corresponding to the morning peak in adverse cardiovascular events. This discovery has potential to address the morning peak in cardiovascular risk and decrease related mortality.
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Multiple lifestyle improvements can reduce the risk of developing diabetes by up to 80%, according to a study of over 100,000 men and women. Additionally, researchers warn that Babesia, a parasitic disease, poses a threat to the nation's blood supply, highlighting the need for donor-screening strategies.
A recent study found that postmenopausal women who smoke have higher androgen and estrogen levels than non-smoking women. Smoking cessation appears to reverse this effect, suggesting a potential mechanism by which tobacco smoke influences chronic disease risk through hormonal mechanisms.
A Norwegian study found a graded increase in atrial fibrillation risk with increasing levels of physical activity in men, but not women. Heavy exercise was associated with a 2-3 fold increased risk, while the majority of heavily exercising men had normal heart rhythms.
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A recent UC Davis study found that people with lower socioeconomic status are more likely to develop heart disease, even after long-term improvements in other risk factors. The researchers suggest that access and adherence to treatments may not account for the differences.
Researchers analyzed data from over 3,000 ICU staff and found a link between female nurse ratios and lower burnout rates. The study also revealed gender-related differences in stress perception and resistance to burnout.
A new study published in BMJ Open found no evidence that patients who underwent a heart ultrasound before major surgery had improved survival rates one month or one year after their operation. In fact, some groups of patients may have worse survival rates if they had undergone an echocardiogram.
Watching TV for six hours a day may shorten life expectancy by almost five years, according to research. Sedentary behavior is associated with a higher risk of death from heart attack or stroke, and TV viewing accounts for substantial sedentary activity.
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A study published in Journal of School Health found that a suicide prevention program significantly reduced teen suicidal behaviors, with significant decreases in considering, planning, and attempting suicide. The Surviving the Teens program taught self-confidence and positive behavior to help teens cope with stress and depression.
A recent Review highlights the urgent need for high-income countries to fund interventions addressing unmet mental health needs of displaced children. Exposure to violence is a major risk factor, while support from family and peers can be protective.
A new risk assessment model predicts development of advanced age-related macular degeneration (AMD) in individuals with early symptoms. The model identifies phenotypic, demographic, environmental, and genetic risk factors, accurately predicting progression and helping determine follow-up examinations and preventive measures.
Researchers found a small but significant association between early life family psychosocial environment and later coronary heart disease. For every extra point on the risky family score, CHD risk rose by 1 percent.
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A strong link between family history and COPD was found in a study of over 1,600 participants. Family history of COPD was identified as a significant risk factor for the disease, even when other factors such as smoking exposure were accounted for.
The study found that risk factors for PTSD among OEF/OIF male veterans were similar to those observed in Vietnam veterans, but identified novel mechanisms of risk for OEF/OIF female veterans. Family relationships during deployment played a more prominent role in explaining PTSD in female veterans than in male veterans.
A recent study suggests that seven potentially modifiable risk factors, including smoking and physical inactivity, contribute to an estimated half of all Alzheimer's disease cases worldwide. By reducing these risk factors by 25%, up to 3 million cases of AD could be prevented globally.
A study by Deborah Barnes found that low education, smoking, physical inactivity, depression, mid-life hypertension, diabetes, and mid-life obesity are associated with up to 51% of Alzheimer's cases worldwide. Lifestyle changes such as increasing physical activity and quitting smoking could potentially prevent some cases.
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Two studies found that engaging in regular physical activity is linked to less decline in cognitive function in older adults. The studies used objective measures of energy expenditure to analyze data and found a significant association between physical activity and lower rates of cognitive impairment.
A new study confirms that a low level of response (LR) to alcohol increases risk for heavy drinking and problems among adolescents. LR is related to more adverse outcomes through partial mediation by peer substance use, positive expectancies, and using alcohol to cope with stress.
A study by Johns Hopkins researchers has discovered a genetic risk factor for sudden cardiac death, specifically a DNA sequence called the BAZ2B locus. Having one copy of this variant increases the risk of SCD by double that of someone without it, while having two copies nearly quadruples the risk.
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A collection of articles in the American Journal of Preventive Medicine explores the health consequences of prolonged sitting time, independent of physical activity levels. Key findings suggest that sedentary behavior is a distinct health risk, with implications for workplace environments and children's health.
A history of psychiatric illness before TBI is strongly predictive of post-TBI psychiatric disorders. Psychiatric symptoms during the acute post-injury period and concurrent limb injuries also increase the risk of psychiatric illnesses.
A new study reveals that several unhealthy lifestyle factors, including weight problems, physical inactivity, and hard drug use, are associated with an increased risk of sexual dysfunctions in both men and women. The study found that up to 91% of women and 78% of men without a partner-related sex life had unhealthy lifestyles.
A study published in the Journal of the American College of Surgeons found that cardiac valve procedure patients' outcomes are influenced by their primary insurance type. Uninsured and Medicaid patients experienced higher risks of mortality, longer hospital stays, and increased total costs compared to those with private insurance.
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A literature review published by the American Academy of Orthopaedic Surgeons found that many fall prevention initiatives used in healthcare facilities are ineffective in preventing hospital falls. The study suggests that hospitals may not be able to prevent most falls due to various risk factors beyond their control.
Research highlights the importance of controlling seizures through effective drug treatment and good compliance in protecting against SUDEP. The study also recommends modifying risk factors such as polytherapy and non-adherence to prescribed medications.
A recent study published in JAMA found that adhering to a healthy lifestyle, including not smoking, exercising regularly, and eating a balanced diet, can significantly lower the risk of sudden cardiac death in women. The study analyzed data from over 81,000 women and found that those who met four key lifestyle criteria had a 92% lower ...
The California Autism Twins Study suggests that both genetic and shared environmental factors significantly increase the risk of autism spectrum disorder (ASD) in twins. Environmental influences such as parental age, low birth weight, multiple births, and maternal infections during pregnancy may greatly increase the risk for ASD.
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