Researchers at Purdue University have developed an oral delivery method for insulin that may eventually treat human diabetes. The method uses a gel-like material to protect insulin from stomach enzymes, allowing it to release the drug in a location where it can work.
Researchers have designed a mini drug pump that can sense blood glucose levels and deliver the right amount of insulin, potentially simplifying the lives of diabetics. The device uses a novel alloy to create a closed-loop system, which could also be adapted for other medications.
Researchers develop tiny coated beads that can release drugs directly onto tumors in response to chemical signals. The beads are designed to remain intact until exposed to sodium-rich blood plasma, at which point they swell and burst explosively, releasing the entrapped drug. This technology has potential for targeted cancer treatment.
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Brown University researchers have developed a novel oral drug delivery system using erodible plastic microspheres that can improve the efficacy of drugs like insulin. The microspheres, engineered with bioadhesive polymers, increase absorption rates and enhance therapeutic effects.
Researchers have developed a prototype drug pump that can monitor its own flow rate, ensuring steady stream of medicine and enabling diabetics to manage their condition more effectively. The device is made on a single silicon wafer and uses a titanium-nickel alloy to flex and regulate fluid flow.
Researchers at Ohio University have developed a nonviral gene therapy system that can express genes outside the nucleus of a cell, making it easier to deliver disease-fighting genes to tumor cells. This system has been successfully used in cell cultures and mouse models to promote anti-cancer activity.
A neural prosthetic system has been recommended for FDA approval, allowing paralyzed people to grasp objects without assistance. The system, developed over 25 years, enables users to regain hand function and perform routine activities with greater independence.
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Johns Hopkins has started performing the new Port-Access technique for single-graft coronary artery bypasses and heart valve replacement and repair. The procedure is designed to reduce trauma, complications, and pain, resulting in shorter hospital stays and quicker recovery times.
Researchers show that taking an inhaled beta-agonist at regularly scheduled times is safe but provides no greater benefit than taking the medication only when symptoms occur. The study also demonstrates that asthma patients continue to have a good response to inhaled beta-agonists even after months of daily use.