A cancer researcher is working on a targeted way to deliver drugs to specific cells, making treatment more precise and effective. The approach uses natural biomolecules to target diseased cells while leaving healthy ones alone.
Researchers have unveiled a new technique to characterize binding interactions of multivalent molecules designed for targeted drug delivery in cancer treatment. This method, using atomic force microscopy, shows promise for optimizing binding affinity and designing better antibodies.
Researchers developed nanoparticles that can target and deliver drugs to prostate cancer cells using aptamers, achieving highly specific and efficient tumour targeting. The bioconjugates successfully adhered to PSMA-positive prostate cancer cells and were rapidly internalised into the targeted cells.
A team at Georgia Institute of Technology has developed heat-controlled drug implants that can release medication over an extended period, targeting conditions like diabetes. The films, made from microparticles, could be triggered by blood glucose monitors to administer insulin or other medications.
A phase III study uses IL13-PE38QQR, a hybrid protein that attaches to specific receptors on tumor cells, to target residual GBM brain tumors. The treatment, convection-enhanced delivery, facilitates infusion of the drug into the brain, bypassing the blood-brain barrier.
Researchers have developed a three-way drug delivery system using vesicles, allowing for the simultaneous release of different materials in a single vehicle. This innovation could minimize toxic side effects and enhance the effectiveness of medications.
Researchers are exploring alternative methods for delivering drugs, including handheld electronic inhalers, dry powder injection and implantable microchips. These innovative systems have the potential to deliver precise doses of medication in a faster and more efficient manner than traditional hypodermic needles.