Research on discovering and developing new drugs. Covers structure-revealing tools, eye-disease mechanisms, protein screening, and once-daily oral medicines.
Researchers at Pacific Northwest National Laboratory have developed two portable detection systems that can identify strategic metals used to make nuclear weapons. The Material Identification System uses eddy current technology to detect metals, while the Ultrasonic Pulse Echo instrument uses ultrasound to characterize container contents.
The new guidelines rank treatment options using data from 69 experts, recommending cognitive-behavioral therapy (CBT) as the primary first-line treatment. The guidelines also suggest starting medication before adding CBT for severe patients, and recommend a trial of clomipramine after failed SSRI trials.
Newborn ferrets' brains develop visual abilities through internal patterns of electrical activity before birth, suggesting an interaction between nature and nurture in brain development. The study found that stimulating the optic nerves disrupted this process, leading to altered neural responses.
Researchers found that men with high homocysteine levels and Factor V Leiden were three times more likely to develop venous blood clots. A 20-fold increased risk was seen in those with both conditions.
A new technology has been developed to address the need for Rh immune globulin, a treatment for pregnant women with Rh-Factor Incompatibility. The approach uses phage display to isolate anti-Rh antibodies from whole cells, offering a promising solution to this long-standing problem.
Researchers have created a mouse model that mimics Familial Combined Hyperlipidemia (FCHL), a disorder causing high cholesterol and triglycerides, leading to premature heart disease. The study suggests APOC3 genetic variations underlie the disease, offering new hope for drug development.
A new company in Florida plans to introduce its revolutionary wheelchair, powered by Oak Ridge National Laboratory's (ORN L) innovative technology. The TransRovr features omnidirectional movement and a three-piece modular construction, allowing for enhanced ergonomics and convenience.