Researchers developed a new tool called SigRM to analyze single-cell epitranscriptomics data, enabling the study of RNA modifications in individual cells. This can provide valuable insights into gene regulation and its impact on health and disease, particularly in complex conditions like cancer.
Researchers at La Jolla Institute for Immunology found that TET enzymes play a crucial role in keeping immune cells on a healthy track, suggesting potential new avenues for controlling cardiovascular disease. The study also identified the minor but important role of TDG enzyme in immune cell demethylation.
A team led by the Department of Energy's Oak Ridge National Laboratory has discovered a novel microbial process that can break down toxic methylmercury in the environment. This process could reduce mercury toxicity levels and support health and risk assessments, particularly in fish consumption.
Researchers trap and observe intermediate stage of DNA repair protein Al McBiotically theft, a process that regulates health conditions such as obesity, cancer, and diabetes. The study provides new insights into how proteins chemically alter biological molecules via oxidative demethylation.
Scientists at Johns Hopkins University have found that a protein called Gadd45b is involved in changing epigenetic marks in brain cells, leading to the birth of new neurons and long-term changes in memory. This discovery may help understand how daily life experiences trigger long-lasting memories.