Add BrightSurf on Google Email

RNA modifications in individual cells better understood with new modelling

Researchers developed a new tool called SigRM to analyze single-cell epitranscriptomics data, enabling the study of RNA modifications in individual cells. This can provide valuable insights into gene regulation and its impact on health and disease, particularly in complex conditions like cancer.

SourceXi'an Jiaotong-Liverpool University·JournalCell Genomics·TypeComputational simulation/modeling·DateDec 5, 2024
Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Hard-working enzyme keeps immune cells in line

Researchers at La Jolla Institute for Immunology found that TET enzymes play a crucial role in keeping immune cells on a healthy track, suggesting potential new avenues for controlling cardiovascular disease. The study also identified the minor but important role of TDG enzyme in immune cell demethylation.

SourceLa Jolla Institute for Immunology·JournalGenome Biology·DateJun 25, 2021

Newly identified microbial process could reduce toxic methylmercury levels

A team led by the Department of Energy's Oak Ridge National Laboratory has discovered a novel microbial process that can break down toxic methylmercury in the environment. This process could reduce mercury toxicity levels and support health and risk assessments, particularly in fish consumption.

SourceDOE/Oak Ridge National Laboratory·JournalScience Advances·DateMay 31, 2017

DNA repair protein caught in act of molecular theft

Researchers trap and observe intermediate stage of DNA repair protein Al McBiotically theft, a process that regulates health conditions such as obesity, cancer, and diabetes. The study provides new insights into how proteins chemically alter biological molecules via oxidative demethylation.

SourceUniversity of Chicago·JournalNature·DateNov 10, 2010

Growth of new brain cells requires 'epigenetic' switch

Scientists at Johns Hopkins University have found that a protein called Gadd45b is involved in changing epigenetic marks in brain cells, leading to the birth of new neurons and long-term changes in memory. This discovery may help understand how daily life experiences trigger long-lasting memories.

SourceJohns Hopkins Medicine·JournalScience·DateJan 8, 2009