Articles tagged with Dna Binding Proteins
Researchers discover byssal threads in marine mussels, which feature a mix of collagenous and elastin-like properties. The unique structure of these threads may inspire the development of biomimetic materials with improved stretchiness and toughness.
Researchers have discovered how key molecules interact in the major pathway regulating cell division. Disrupting this pathway may force cancer cells to divide prematurely, favoring their death. A class of molecules that inhibit Cdc25C has also been identified, suggesting a potential target for cancer therapies.
Researchers at Johns Hopkins University discovered that RNA- and DNA-binding proteins have the same shape, a configuration of three coils called alpha helices. This similarity suggests that the protein could be an ancient ancestral form of other proteins crucial to embryonic development.
Scientists at UC Berkeley designed a protein that toggles between two structures upon binding a small molecule, enabling detection of carcinogens like benzene. The newly designed protein could also be used as a molecular switch or zipper to join proteins together.
Researchers at University of Rochester and NIH discover new HAT that plays critical role in transcription, providing strong evidence for chromatin-unfolding mechanism of gene activation. The finding has significant implications for understanding cell survival, proper development, and evolution.
Transforming growth factor beta (TGFb) uses a simple signaling pathway to convey distinct functions in different tissues, despite its multifaceted role. Researchers have identified the key steps involved in translating TGFb signals into individual patterns of gene expression.