Scientists have developed a fusion protein that successfully blocks replication of SARS-CoV-2 and related viruses in cell culture tests. The protein combines ACE2 with human antibody fragments, providing reliable protection against future mutations.
A team at Rockefeller University has discovered an antibody signature that may increase the risk of severe secondary dengue infections. The study found that patients with more serious disease have high levels of antibodies whose Fc regions lack a particular sugar, which strongly activate immune cells and lead to bleeding disorders.
Researchers at Rockefeller University discovered a new mechanism to create more effective and efficient vaccines against the flu virus. By harnessing modified antibodies, they were able to elicit broad protection against multiple strains of the virus.