An international research team led by the University of Göttingen has unraveled the mechanism for the biosynthesis of salicylic acid in plants. The study reveals that isochorismate-derived compounds accumulate when a specific gene is removed, leading to the formation of salicylic acid.
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A University of Cincinnati study found that abnormal thyroid function is present in just over 6% of psychiatrically hospitalized youth. The research suggests that targeted screening should focus on patients with a family history of thyroid disease, recent weight gain, or treatment with specific medications.
In a groundbreaking study, researchers discovered that anemonefish undergo male-to-female sex changes first in their brains before gonads are affected. The transition occurs independently of the gonads and can take months or years to complete.
Researchers at KIST developed an eco-friendly nanocomposite catalyst made from agricultural byproducts to effectively remove environmental hormones from sewage and wastewater. The catalyst achieved a high removal rate of over 95% in less than one hour, outperforming existing methods.
A large-scale study found that high levels of air pollution negatively affect ovarian reserve and female fertility marker anti-Mullerian hormone (AMH) levels in Italian women. Exposure to particulate matter and nitrogen dioxide increased the risk of reduced AMH concentrations, leading to a lower ovarian reserve.
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Researchers found that decreasing day length alone triggers dramatic weight loss in Siberian hamsters, regardless of food or temperature. The study reveals the cascade of signals that prepare the hamsters for winter, controlled by thyroid hormone and gene expression.
Early-life adversity impacts executive function skills, such as focusing and organizing tasks, and brain chemistry, affecting stress hormones like cortisol. This snowball effect contributes to social and emotional challenges throughout childhood.
Researchers at the University of Cordoba have found a relationship between iron deficiency responses and the response caused by certain beneficial microorganisms, enabling improved iron uptake in plants. The study suggests that applying these rhizosphere microorganisms can induce responses to iron deficiency, benefiting crops such as p...
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A panel of international experts recommends against routine hormone treatment for adults with subclinical hypothyroidism, as it does not improve quality of life or symptoms. The guideline applies to most adults with the condition, except those trying to become pregnant or with severe symptoms.
Researchers found that chronic stress can harm ovarian function and reduce the number of primordial follicles, but blocking ghrelin receptor improved ovarian function. The study suggests that eating habits may be able to mitigate the effects of stress on fertility.
A new study by Penn State researchers finds that male fence lizards' physical traits and behaviors used to attract mates remain unchanged under low levels of stress. This suggests that these traits are more resilient to stress than previously thought.
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A team of scientists has mapped a molecular complex that could aid in the development of better medications with fewer side effects for osteoporosis and cancer. The findings provide insight into how PTH1R interacts with key messengers to regulate calcium levels.
A study published in Frontiers found that taking a 20- to 30-minute nature experience significantly lowers cortisol levels. The research suggests a daily dose of 'nature pills' could be a simple and effective way to reduce stress.
Researchers at Georgia Institute of Technology developed a technique for administering contraceptive hormones through special backings on jewelry, allowing for improved user compliance with drug regimens. The technology may also be used to deliver other drugs through the skin.
A study found that sleep quality decreases in the late luteal phase, just before menstruation, with less sleep efficiency, longer wake after sleep onset, and higher sleep fragmentation index. Caloric restriction also negatively affects sleep during this period.
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Researchers are analyzing hair samples to study how hormones and environmental factors influence puberty. The goal is to understand the mechanisms that trigger puberty and how personal experiences shape hormone changes.
A study found that thyroid hormones hindered the ability of early mammals to regenerate their heart tissue, leading to modern humans' susceptibility to irreparable damage. The researchers discovered a connection between these hormones and the transition from ectothermic to endothermic animals.
A new study found that high-intensity exercise performed in the evening does not negatively impact sleep quality, but may actually reduce feelings of hunger. The research suggests that afternoon and evening exercise may be more effective for weight loss due to increased power output.
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A recent study published in the journal Nutrients found that vegan meals increased beneficial gastrointestinal hormones in individuals with obesity, type 2 diabetes, and healthy participants. This increase in gut hormones can help regulate blood sugar, enhance insulin secretion, promote satiety, and support weight management.
Researchers at Iowa State University discovered a link between the satiety hormone Cholecystokinin and reduced Alzheimer's disease risk, with higher levels associated with a 65% decrease in cognitive impairment. The study suggests that dietary factors may play a role in preventing or slowing disease progression.
A new long-acting contraceptive designed for self-administration via microneedle patch technology has shown promise in animal testing, providing a therapeutic level of contraception for over a month with a single application. The experimental patch uses biodegradable polymers to slowly release the contraceptive hormone levonorgestrel.
A study published in JNeurosci found that one night of sleep loss increases the desire for junk foods, as measured by brain activity and hormone levels. The researchers suggest that a lack of sleep can promote overeating and obesity risk through increased food desirability.
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New research found that ghrelin hormone makes people associate food odours with reward, leading to increased eating and obesity risk. Ghrelin also reduces response time and increases pleasantness of food images
Studies found that at least one hormone or pharmaceutical contaminant was present in untreated groundwater at 6% of sites, with higher exposure risks for individuals using domestic wells. The presence of chemicals also threatens ecosystems, particularly through stormwater management practices.
Researchers found that spinal cord injuries disrupt circadian rhythms of hormones, body temperature and movement, resulting in widespread disruption throughout the body. This could lead to new recovery efforts targeting daily schedules, sleep, physical rehabilitation and bright light.
Research at Hokkaido University found that the body's stress response is weaker in the evening, potentially making individuals more susceptible to stress. Cortisol levels were significantly higher in volunteers who took a morning stress test compared to those who took an evening test.
A new study reveals that women can be as resilient to extreme physical activity as men, contrary to previous claims about gender differences. The research found no significant negative health effects in six female participants who completed a transantarctic expedition.
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Researchers discovered that secretin stimulates appetite suppression and increased brown fat heat production in mice. Human volunteers showed similar results, suggesting a link between secretin and satiation. This finding may lead to new approaches for treating obesity.
A new review highlights growing evidence that universal thyroid testing in early pregnancy can reduce obstetric complications and safeguard fetal brain development. However, the risks of overdiagnosis and overtreatment must be carefully considered to avoid unwarranted patient anxiety and potential harm.
A study published in Neurology found that middle-aged individuals with high cortisol levels experienced impaired memory and reduced brain volume compared to those with average cortisol levels. The study also found no links between low cortisol levels and memory or brain size.
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A genetic polymorphism in the D2 enzyme affects thyroid hormone conversion, leading to hypothyroidism-like symptoms in mice and potentially affecting human patients. The study aims to develop a new treatment agent to address this issue.
Research by Ohio University Associate Professor Dr. Peggy Zoccola found that open disclosure of LGBT identity to families leads to lower cortisol levels, indicating reduced stress and potential health benefits.
A recent study of 744 infertile men found that 15.4% had undiagnosed prediabetes, with factors including older age and high follicle stimulating hormone levels linked to the condition. The study suggests that infertility in men may be associated with impaired glucose metabolism.
A new study by Imperial College London reveals that kisspeptin, the master regulator of reproduction, affects brain activity in healthy volunteers, leading to decreased sexual aversion and increased brain activity associated with sexual arousal. The hormone also boosts networks involved in mood and depression.
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Scientists have discovered a neural superhighway that enables rapid communication between the gut and brain, contradicting decades of research on hormonal transmission. This breakthrough has profound implications for our understanding of appetite and other gut-related disorders.
Subordinate females in naked mole-rat colonies become more responsive to pup vocalizations after consuming queen's feces or estradiol, suggesting a unique mode of communication.
A new study published in Human Reproduction journal found that men who wear boxer shorts have higher sperm concentrations than those who wear tighter fitting underwear. The researchers also discovered a link between the type of underwear and lower levels of follicle-stimulating hormone (FSH), which stimulates sperm production.
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Research in genetically altered mice reveals that paternal genes can affect the type of care a mother provides to her offspring both before and after birth. This study suggests that a father's genes can impact maternal behavior, potentially affecting the wellbeing of the new baby and their lifelong mental health.
New research reveals that gut hormones play a crucial role in addiction treatment, with ghrelin and GLP-1 analogs showing promise in reducing cravings. The study suggests that medications affecting these hormones could be repurposed to help manage drug craving and relapse.
Researchers found that a fight-or-flight response can trigger the overproduction of white blood cells, leading to inflammation and increased risk of heart attacks in people with diabetes. Beta 2 blockers may help reduce this risk by limiting the proliferation of inflammatory myeloid cells.
Researchers identified autoantibodies against adrenocorticotropic hormone (ACTH) in aggressive male prison inmates, showing altered cortisol secretion and decreased time to attack in mice. These findings suggest potential molecular mechanisms underlying human aggression and stress response.
Researchers at Tokyo Institute of Technology identified USP8 as a key enzyme controlling large collagen carrier formation. The enzyme inhibits collagen secretion when active, promoting its transport instead.
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Universal thyroid testing for pregnant women could detect mild thyroid problems that are currently missed in up to 75% pregnancies. However, experts debate the potential risks and benefits of this approach, with some arguing it may not provide significant improvements in pregnancy outcomes.
Researchers developed an artificial metalloenzyme that can penetrate a mammalian cell and accelerate hormone release, activating a gene switch to create a fluorescent protein. This breakthrough enables the modification of cell functions on a genetic level or the creation of drugs from harmless precursors.
Researchers at Joslin Diabetes Center have discovered a hormone in fat that boosts metabolism during exercise and cold exposure. The hormone, 12,13-diHOME, is released from brown fat and offers beneficial metabolic effects. Further studies are underway to understand its role in obesity and metabolic disease.
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Researchers discovered naturally occurring hormones 'notum' and 'lipocalin-5' that accelerate fat burning and protect against Type 2 diabetes. Lipocalin-5 also enhances muscle's ability to metabolize nutrients, reducing obesity and diabetes risk. The findings could lead to new drugs for halting obesity and heart disease.
A new study found higher cortisol levels in medical students during the summer months than in winter. The research contradicts traditional notions of increased stress in winter and relaxed ease in summer.
The Bajau people's larger spleens enable them to dive longer and deeper by injecting more oxygenated red blood cells into the circulation. Genetic analysis reveals a link between increased thyroid hormone levels and enhanced diving ability in this Southeast Asian group.
A study found that the Bajau people have genetically enlarged spleens, allowing them to free dive for extended periods. The discovery could lead to new insights into Acute Hypoxia and its treatment.
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A new compound called EP055 has been discovered to stop sperm temporarily without affecting hormones, offering a potential 'male pill' alternative. The study found that the compound significantly slowed sperm mobility, limiting fertilization capabilities.
Researchers at UT Southwestern Medical Center identify a hormone that stimulates thirst in response to nutrient stresses, challenging traditional views on hydration. The study's findings suggest that FGF21 works through a novel pathway to increase water intake, potentially limiting alcohol consumption and protecting against its effects.
Researchers at the University of Birmingham have discovered a way for plants to 'hedge their bets' by germinating seeds at different times, reducing variability in agriculture. By understanding this process, farmers may be able to increase potential yields and address agronomic challenges.
A review suggests that exposure to thyroid-hormone-disrupting toxins in pregnant women and children may lead to increased incidence of brain development disorders. This has significant implications for child health and underscores the need for targeted public health strategies.
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A novel study found sex-specific responses to maternal diet and androgen excess in animal offspring, with female offspring developing anxiety-like behavior due to maternal androgen exposure. Male offspring were unaffected by maternal androgens but displayed anxiety-like behavior on a high-fat-high-sucrose diet.
Researchers found a crucial link between chronic fatigue syndrome and lower levels of key thyroid hormones. CFS patients had lower serum levels of T3 and T4, but normal thyroid-stimulating hormone, and higher levels of reverse T3, which may indicate reduced tissue T3 levels.
A large population-based study found that patients on levothyroxine had lower quality of life and more comorbidity than those not taking the hormone. The study also showed that comorbidity had a greater negative impact on the quality of life of LT4 users.
Researchers have discovered that changes in social behavior during adolescence are not triggered by pubertal hormones. Using Siberian hamsters as a model, the team found that behavioral shifts, such as play-fighting to social dominance, occur at the same time regardless of puberty timing.
A phase II clinical trial showed that NGM282 significantly reduced liver fat content in patients with NAFLD and NASH. The treatment, a non-tumorigenic variant of an endocrine gastrointestinal hormone, has no FDA-approved treatments for these conditions.
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A retrospective study of patients with laryngeal cancer who underwent radiation treatment found that those with low thyroid hormone levels were more likely to experience fistula formation and prolonged hospital stays. Researchers propose administering a common hormone supplement, levothyroxine, to prevent these complications.
Researchers found that prenatal exposure to androgens had no significant association with girls' time spent with either boys or girls. However, girls with classical CAH spent more time in male-typical activities and less time in female-typical activities. This study suggests that gender development is a complex process influenced by bo...