Researchers at Salk Institute find that a high-fat diet amplifies the effects of FGF21, granting mice resistance to obesity and associated diseases. The study provides insight into potential new therapies for mitochondrial and metabolic diseases in humans.
Women under chronic stress have significantly lower levels of klotho, a hormone that regulates aging and enhances cognition. The study found even lower levels of klotho in women with clinically significant depressive symptoms, suggesting a link between psychological influences and klotho.
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A large analysis found that subclinical hyperthyroidism is associated with an increased risk of hip and other fractures, including spine. The study pooled data from over 70,000 participants and found no association between subclinical hypothyroidism and fractures.
A study found that 2 out of 10 plastic teethers contained significant endocrine activity, including methylparaben and unidentified compounds. The presence of parabens in one product is unusual, highlighting the need for manufacturers and regulators to address chemical exposure in baby products.
Scientists design a peptide that binds to ghrelin and Y2 receptors, reducing appetite in obese mice. The compound shows promise as an obesity treatment targeting the complex system of hormones regulating appetite.
A team of scientists is working on a project to create new pesticides that target specific insect species without harming beneficial ones. By mimicking the hormone systems of these insects, researchers hope to disrupt their reproductive cycles and prevent population explosions.
Michigan State University researchers are investigating whether belly fat hormones cause high blood pressure by communicating with blood vessels in the abdomen. Visceral fat, a harmful type of fat that surrounds organs and blood vessels, is believed to play a key role in this process.
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A study discovered that smoking can raise the likelihood of producing twins in women with certain genetic backgrounds, particularly those with a variant in the TP53 gene. The researchers found significant interactions between smoking and genetic variations, suggesting a possible explanation for reports of mothers of twins being more li...
UGA researchers have identified a hormone receptor that plays a key role in regulating female mosquito reproduction, enabling them to produce eggs after consuming blood. The discovery fills a major gap in understanding how mosquitoes reproduce and could potentially lead to strategies for controlling mosquito populations.
Recent research suggests that irisin, believed to travel from muscle to fat tissue after exercise, may not exist in humans. New tests used in previous studies found antibodies were poorly vetted and nonspecific, leading to false positive results.
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A BBC News team received the Endocrine Society's Award for Excellence in Science and Medical Journalism for their coverage of hormonal fluctuations at different times of day. The winning package, 'The Day of the Body Clock,' included TV, radio, and online coverage from May 13, 2014.
Research found that exposure to phthalates early in pregnancy disrupts essential pregnancy hormone levels, leading to adverse effects on male genital development. Higher phthalate levels were linked to lower hCG levels and shorter anogenital distance in male babies.
Researchers found that pregnant lemur moms carrying boys produce simpler scents with fewer odor compounds compared to those carrying girls. The change in scent patterns correlates with changes in blood hormone levels. The study provides the first evidence of a pregnant mother's scent differing depending on the sex of her baby.
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Researchers at the Technische Universität Dresden have successfully transplanted adrenal cells encapsulated in a bioreactor, paving the way for future human transplantation. This breakthrough could benefit patients with adrenal insufficiency and congenital diseases such as 21-hydroxylase deficiency.
Researchers at USC discovered a compound that extends the life span of female fruit flies by 68%, challenging existing methods used to study genetic causes of aging. The finding opens up new avenues for investigating longevity and identifies potential candidate genes and mechanisms.
Researchers have found that ghrelin increases sexual activity and motivation in mice, suggesting a possible role for the hormone in regulating human sexuality. Further research is needed to understand the effects of ghrelin on humans, but ghrelin inhibitors may hold promise as new treatments for sex addiction.
Researchers successfully mutated the thyroid hormone receptor in tadpoles, disrupting hind limb development and providing insight into the importance of hormones in early development. The study also has potential applications in understanding human developmental disorders such as cretinism.
A new study reveals that ghrelin, a key regulator of appetite, plays an unexpected role in early brain development and influences long-term appetite regulation. The research suggests a link between gut-brain axis maturation and later susceptibility to obesity, diabetes, and cardiovascular disease.
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Researchers discovered that knocking down a single gene can prevent stress-induced female infertility and miscarriage in rats. The study found that this genetic silencing restored reproductive success to levels comparable to non-stress controls.
A new NYIT study reveals that rats treated with thyroid hormones had a reduced risk of developing dangerous heart arrhythmias following a heart attack. The findings could have important implications for future treatment of human patients with heart failure, who often suffer from atrial fibrillation.
A new study found that endocrine disrupting chemicals can interfere with thyroid hormone action in pregnant women and may travel across the placenta to affect fetal brain development. The study used a prospective birth cohort of 164 pregnant women and found associations between high levels of CYP1A1 enzyme and thyroid disruption.
Scientists have discovered the role of thyroid hormone in the formation of zebrafish stripes and have found that cells responsible for producing orange color can transform into xanthophores through a process called 'transdifferentiation'. This finding could provide clues to regeneration of tissues and organs without stem cells.
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A study found that thermal receipt paper can transfer high amounts of BPA to hands and blood levels after handling, particularly in women. This raises concerns about the potential health risks associated with prolonged exposure to BPA through daily activities.
A new study found that PCBs can infiltrate the placenta during pregnancy and affect thyroid hormone activity at the cellular level. This may be particularly concerning for pregnant women who smoke, as it can lead to higher levels of the enzyme CYP1A1 in the placental tissue.
Researchers identify a bacterial protein that mimics the satiety hormone, leading to variations in food intake. A blood test for this protein could lead to specific treatments for eating disorders, while neutralizing the protein may prevent dysregulation of food intake.
A study published in CMAJ found that metformin increases the risk of low thyroid-stimulating hormone levels in patients with hypothyroidism. Metformin monotherapy was associated with a 55% increased risk of low TSH levels compared to sulfonylurea therapy.
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The study found that younger people have a more robust immune response to grief, while elderly people are more likely to experience reduced immune function. The researchers suggest that hormonal supplements could be used to help individuals at risk of stress, but highlight the importance of a strong support network in managing grief.
A study published at Lund University found that spinach extract containing thylakoids reduces hedonic hunger by up to 95% and increases weight loss by 43%. The study showed improved appetite control, healthier eating habits, and increased weight loss in participants who took the thylakoid extract before breakfast.
Women seek anti-aging clinicians to treat menopausal symptoms, valuing personalized attention and perceived safety of bioidentical hormones. The study found that these women prioritize relieving symptoms, feeling energized, and avoiding chronic illnesses associated with aging.
A study by the Endocrine Society found that women with vitamin D deficiency were nearly half as likely to conceive through IVF as those with sufficient levels. Women with adequate vitamin D levels had higher-quality embryos and increased chances of successful implantation.
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A study found that retinoblastoma protein is less active in male brain cells, leading to higher brain tumor rates and poorer survival rates. The researchers believe this discovery could lead to more effective therapies and treatments.
Researchers have successfully used kisspeptin to stimulate ovulation in women undergoing IVF treatment, reducing the risk of OHSS. Twelve babies were born after their mothers received the hormone injection, with 12 becoming pregnant and nine having healthy embryos transferred.
Levothyroxine treatment improved cognitive and learning abilities in naturally aged mice by increasing choline acetyltransferase and acetylcholine levels. The supplement also enhanced superoxide dismutase activity and synapse function, suggesting a potential therapeutic strategy for age-related cognitive deficits.
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A new study by NYIT College of Osteopathic Medicine professor A. Martin Gerdes found that administering low doses of thyroid hormone can restore hormone levels in the hearts of rats with diabetes and prevent deterioration of heart function.
Researchers found that low levels of the stress hormone cortisol are strongly correlated with voting behavior, while age is also a predictor. The study suggests that biological factors can play a role in voter turnout, complementing social and demographic variables.
Cathryn Jakobson Ramin received the Endocrine Society's Award for Excellence in Science and Medical Journalism for her investigation into hormone compounding risks. Her article, 'The Hormone Hoax Thousands Fall For', found inconsistencies in hormone prescriptions across multiple pharmacies.
A recent study has found that hypothyroidism can cause impaired driving abilities, comparable to the effects of drinking alcohol. The research suggests that patients with significant hypothyroidism should avoid driving until they have been treated with thyroid hormone.
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A study found that older adults have fewer taste buds, leading to higher fasting blood sugar levels and lower adiponectin levels. The researchers suggest a link between the number of taste buds and glucose metabolism during aging.
A new study found that elevated stress hormones are associated with structural brain changes and short-term memory deficits in aged rats. The research suggests that stress may accelerate age-related cognitive decline by altering brain connections and function in the prefrontal cortex.
Research at the University of Iowa found a link between high cortisol levels and gradual loss of synapses in the prefrontal cortex, leading to short-term memory lapses. Elevated cortisol can cause synapse shrinkage and disappearance, particularly in older adults, potentially slowed by treatments targeting cortisol reduction.
Researchers develop computer model to speed up search for compound that activates FFA4 protein, a key player in appetite regulation and glucose uptake. The model aims to identify molecules that bind to the protein, potentially leading to a new obesity treatment.
A UCLA research team has discovered a new hormone called erythroferrone, which regulates the iron supply needed for red blood-cell production. Erythroferrone suppresses hepcidin, allowing more iron to be made available for red blood-cell production and potentially treating iron disorders.
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A new study found that PMS before menopause is linked to a poorer quality of life after menopause, particularly with depression, poor sleep, and memory problems.
Researchers tested whether ancestral human diets, or paleo diets, result in better appetite suppression. They found that high-fiber plant-based diets likely do not lead to increased SCFAs and appetite suppression, but rather may help baboons maintain grazing all day to consume enough nutrients.
Research from Washington State University found that children who participate in horse-riding programs have lower stress hormone levels. The study, which measured cortisol levels in saliva samples, suggests a potential prevention strategy for young adolescents at risk of developing physical and mental health problems.
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A team of researchers found that differences in response kinetics dictate differential sensitivity to different features of pulsatile hormone inputs. The study explored the mechanism underlying dynamic gonadotropin-releasing hormone (GnRH) signalling using live cell imaging and mathematical modelling.
Scientists propose that conventional steroid treatments deliver medication in a way that disrupts the body's natural hormone release patterns, leading to debilitating side effects. The report recommends developing novel techniques to mimic these natural cycles, which could alleviate suffering for patients.
A recent study has demonstrated that women's preferences for facial attractiveness in professional cyclists coincide with improved endurance performance. The research, conducted by Erik Postma at the University of Zurich, analyzed over 800 portraits and found that attractive riders fared better during the Tour de France.
Researchers found that a protein molecule on stem cells interacts with extracellular matrix and thyroid hormones to promote brain growth. Iodine deficiency in pregnant women can lead to abnormal brain development due to the lack of thyroid hormones.
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Research found that shivering releases irisin, a hormone that stimulates calorie-burning brown fat and improves metabolism. This mechanism is similar to exercise-stimulated secretion of irisin, suggesting potential benefits for treating or preventing obesity.
Researchers discovered a novel metamorphosis hormone that triggers the transformation of moon jellyfish from polyps to medusas in response to cold temperatures. This understanding may offer new methods for controlling moon jellyfish blooms and preventing ecological damage.
A study published in Environmental Science & Technology found that bottlenose dolphins in Barataria Bay, Louisiana, have lung damage and adrenal hormone abnormalities. The researchers believe that the Deepwater Horizon oil spill may be responsible for these health effects.
Eating a tomato-rich diet for 10 weeks increased adiponectin levels by 9 percent in postmenopausal women, reducing breast cancer risk. Regular consumption of fruits and vegetables is believed to promote breast cancer prevention in at-risk populations.
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A new study found that obese children have higher stress hormone levels than normal-weight peers, with elevated cortisol concentrations detected in hair samples from age 8. The observational case-control study analyzed hair samples from 20 obese and 20 normal weight children to measure long-term cortisol levels.
A study found that bonobos have higher levels of thyroid hormone T3 until adulthood, unlike humans and chimpanzees. This might impact their social behavior and cognitive development, potentially leading to delayed maturation.
A recent international study found two lower-dose intrauterine contraceptive systems to be highly effective and well-tolerated over a three-year period. The devices were easier to use in women who had not delivered a child or had delivered by cesarean section, making them a suitable alternative for women seeking reduced hormone exposure.
New research suggests that 55% of bilateral adrenal Cushing's syndrome patients have genetic mutations predisposing to adrenal tumors. Genetic screening may help identify affected family members, potentially preventing disease progression and eliminating current treatment practices.
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A new hormone therapy has been shown to improve the integration of bone grafts used in head and facial reconstruction surgeries. The treatment, which uses parathyroid hormone, enhances bone formation around the grafts and prevents scar tissue from forming, leading to better outcomes for patients.
Women who underwent bariatric surgery reported significant improvements in overall sexual function, including desire, arousal, lubrication, and satisfaction. Additionally, they experienced gains in reproductive hormones and psychological status.
Women who underwent bariatric surgery experienced significant improvements in sexual functioning, including arousal and satisfaction, as well as better reproductive hormone levels and reduced depressive symptoms. They also reported improved body image after weight loss.