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UCSF study reveals mechanism of telomerase enzyme that could lead to target for cancer therapy, cell regeneration

Researchers at UCSF have discovered a region in the telomerase enzyme that could be targeted to kill cancer cells and regenerate damaged cells. The discovery provides new insights into the mechanism of telomerase and its potential as a therapeutic target, as well as its role in regulating cell life span.

Scientists target microbe with sleeker antisense agent

Researchers at the University of Rochester have created a remarkably short antisense compound that targets Pneumocystis carinii, an opportunistic pathogen causing pneumonia in people with weakened immune systems. The breakthrough marks a step toward designing drugs that knock out vital sections of molecules essential for the microbe's ...

SourceUniversity of Rochester·JournalProceedings of the National Academy of Sciences·DateJun 25, 1999