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A very long, winding road: Developing novel therapeutics for metastatic tumors

Researchers highlight difficulties in targeting metastatic tumors and propose two- and three-drug combinations to achieve effective tumor control. They also emphasize the need for simultaneous blocking of primary driving oncogene, evolving resistance mechanism, and secondary survival pathway.

SourceImpact Journals LLC·JournalOncoscience·TypeCommentary/editorial·DateFeb 23, 2024

First estrogen receptor mutation found in a young woman

Researchers identified a young woman with an estrogen receptor-α mutation that blocks the hormone's action, resulting in high estrogen levels and reproductive issues. The study found that the woman had significantly elevated estrogen levels compared to normal ranges, despite having no effect from estrogen.

SourceMedical College of Georgia at Augusta University·JournalNew England Journal of Medicine·DateJul 11, 2013

Protein stops growth of brain tumor, OHSU study shows

A study published in Clinical Cancer Research shows that Herstatin blocks the growth of brain tumors by inhibiting signaling inside tumor cells. The treatment has shown promise as a viable alternative to traditional brain tumor treatment methods, particularly for glioblastoma, the most deadly form of brain cancer.

SourceOregon Health & Science University·JournalClinical Cancer Research·DateJan 27, 2005
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.