Researchers highlight difficulties in targeting metastatic tumors and propose two- and three-drug combinations to achieve effective tumor control. They also emphasize the need for simultaneous blocking of primary driving oncogene, evolving resistance mechanism, and secondary survival pathway.
Researchers found that a combination of natural infection and vaccination produces maximally potent antibodies against COVID-19. The study suggests that repeated exposures to the spike protein can improve the immune system's ability to produce high-quality antibodies against variants.
Researchers identified a young woman with an estrogen receptor-α mutation that blocks the hormone's action, resulting in high estrogen levels and reproductive issues. The study found that the woman had significantly elevated estrogen levels compared to normal ranges, despite having no effect from estrogen.
A study published in Clinical Cancer Research shows that Herstatin blocks the growth of brain tumors by inhibiting signaling inside tumor cells. The treatment has shown promise as a viable alternative to traditional brain tumor treatment methods, particularly for glioblastoma, the most deadly form of brain cancer.