Articles tagged with Ribosomal Dna
Researchers at Stowers Institute for Medical Research have identified the precise location where human chromosomes break and recombine to form Robertsonian chromosomes. The study reveals that repetitive DNA sequences play a central role in genome organization and evolution, explaining how these rearrangements form and remain stable.
A study reveals that epigenetic changes associated with aging in adults do not occur before sexual maturity. In fact, rDNA copy numbers and methylation increase during childhood and adolescence, suggesting cells actively maintain a youthful state to ensure efficient protein production.
Researchers at Tokyo Institute of Technology developed a method to precisely control the timing of DNA droplet division, mimicking biological Liquid-Liquid Phase Separation (LLPS) droplets. This breakthrough enables precise control over synthetic droplet dynamics, key to developing bio-inspired systems.
A new study analyzed 500,000 individuals and found a strong statistical association between rDNA copy number and well-established markers of systemic inflammation, as well as kidney function. The research suggests that wider genome analysis could bring opportunities for preventative diagnostics and novel therapeutics.
Scientists at Umeå University have identified how a protein complex called the Mediator regulates gene expression, leading to slower cell division. This discovery may pave the way for new treatments for diseases related to uncontrolled cell growth, such as tumors.
The study reveals significant differences in the nucleolus organizing region (NOR) of the two species, which has major implications for blight-resistance in American chestnut restoration. Researchers used fluorescent in situ hybridization to analyze the NOR region and found unique DNA arrangements.
Researchers have identified a new mechanism for removing RNA-protein crosslinks induced by aldehydes, which can damage cellular function. This discovery sheds light on the effects of aldehydes on human cells and may be particularly important for maintaining cell function in older individuals.
Scientists from the University of North Carolina at Charlotte review nucleolar DNA damage response pathways to combat cancer. By attacking these mechanisms, researchers aim to disrupt cancer's reproduction and growth.
Scientists at UEA have identified a way to determine the age of lobsters using DNA. The method is based on quantifying DNA changes that accumulate with age within a lobster. This breakthrough could help manage lobster fisheries more sustainably by providing accurate estimates of lobster ages.
A study by the Stowers Institute for Medical Research found that cancer cells often lose copies of repetitive sequences known as ribosomal DNA, which may enable faster proliferation but also render them more sensitive to DNA damage. This could potentially be exploited by DNA-damaging chemotherapeutics.
Scientists at the Weizmann Institute discovered that bacterial DNA forms a crystalline organization when exposed to stress, providing effective protection against oxidative agents and starvation. This finding may lead to the development of more efficient methods to fight bacterial diseases.
Scientists have discovered a unique organelle-like structure, dubbed the dumposome, which breaks down 15-20% of an organism's DNA during reproduction. This process is thought to be essential for streamlining genetic material and may be more common in other organisms than previously thought.