Articles tagged with Vitamin D
Researchers at North Carolina State University have found that vitamin D deficiency during early development can disrupt the metabolic balance between growth and fat accumulation in zebrafish. The study suggests a linkage between vitamin D and metabolic homeostasis, leading to obesity and stunted growth.
Hospitalized COVID-19 patients with vitamin D sufficiency had a significant decreased risk for adverse clinical outcomes, including becoming unconscious, hypoxia, and death. Vitamin D also lower blood levels of inflammatory marker C-reactive protein and higher blood levels of lymphocytes.
A recent study suggests that free, circulating vitamin D levels in the blood may be a better predictor of future health risks in aging men than total vitamin D. The study found that higher levels of free 25-hydroxyvitamin D were associated with a lower risk of death, while free 1,25-dihydroxyvitamin D was not predictive of mortality.
A retrospective study of 489 patients found an association between vitamin D deficiency and the likelihood of becoming infected with COVID-19. Patients with vitamin D deficiency were almost twice as likely to test positive for the coronavirus compared to those with sufficient levels.
The study examines the link between vitamin D status and COVID-19 test results, finding that patients with higher vitamin D levels tend to have better outcomes. Additionally, treatment for insufficient vitamin D levels is also linked to improved test results.
A placebo-controlled clinical trial found that vitamin D supplements did not prevent severe asthma attacks in at-risk children. The study, led by Juan C. Celedón, followed nearly 200 children with moderately low vitamin D levels for three years and showed no benefit from the supplements.
A new study found that vitamin D supplementation is associated with a decrease in Megamonas bacteria and C. difficile colonization in infants, suggesting potential benefits for childhood health.
A study found that taking vitamin D and calcium supplements twice daily can reduce the chances of getting vertigo again, especially for those with low vitamin D levels. The study showed a 24% reduction in annual recurrence rate among participants who took supplements.
A new study found that 20% of middle-aged UK South Asians have a very severe vitamin D deficiency, which can lead to health problems such as osteomalacia. The study also identified factors like geographic location and BMI as contributors to the deficiency, highlighting the need for targeted public health campaigns.
A large randomized clinical trial involving over 18,000 participants found no significant benefit from vitamin D supplementation in preventing depression or improving mood. The study's results confirm longstanding questions about the effectiveness of vitamin D in reducing depression risk.
A study published in PLoS ONE found that inadequate calcium and vitamin D intake are prevalent among the US population, particularly those living below the poverty line. The research highlights the significant risk of osteoporosis for men and women from low-income backgrounds, with non-Hispanic Black men facing a two-fold increased risk.
A study of 782 COVID-19 positive and 7,025 negative patients found low plasma 25(OH)D levels to be an independent risk factor for COVID-19 infection and hospitalization. The association was strongest among older adults, with two peak age groups showing increased risk: 25 and 50 years old.
A new study found that vitamin D supplements reduced the risk of colitis by 65% in patients receiving immune checkpoint inhibitors for melanoma. The findings suggest that vitamin D supplementation could be a safe and cost-effective approach to preventing immunotherapy's gastrointestinal toxicity.
Researchers from the University of South Australia suggest that Vitamin D could mitigate chemotherapy-induced intestinal mucositis by suppressing inflammation and enhancing T-cell function. The study highlights the potential benefits of Vitamin D in reducing damage to the gut microbiome caused by chemotherapy agents.
A good vitamin D status is associated with a lower cancer risk, particularly in colon and blood cancers. Vitamin D responsiveness varies between individuals, affecting their need for supplementation.
A new study has found an association between low average levels of vitamin D and high numbers of COVID-19 cases and mortality rates across 20 European countries. Vitamin D modulates the response of white blood cells, preventing excessive inflammatory cytokine release, which is a key factor in COVID-19 severity.
A study of over 3,000 adults found that higher vitamin D intake from food sources was associated with lower rates of cardiovascular events, particularly in men. The researchers suggest that increased vitamin D consumption may protect against heart-related problems.
Researchers discovered genetic variants linked to vitamin D concentration and found that certain genes influence the body's ability to make vitamin D in response to sunlight. These findings provide new insights into how our bodies handle vitamin D and may help explain why low levels are associated with poor health.
Maintaining vitamin D receptor levels in pancreatic cells may protect against diabetes development and counteract cell damage. Researchers found that sustained VDR expression preserves β-cell mass and function, reducing inflammation and hyperglycemia.
A Rutgers-led study found that vitamin D levels greater than 12 nanograms per milliliter are associated with a higher rate of walking at 30 and 60 days after hip fracture surgery. Vitamin D deficiency is common in elderly patients with hip fractures, often occurring together with malnutrition.
A recent study published in Nutrients found that 65% of college basketball players were vitamin D insufficient at baseline. Athletes with darker skin pigmentation exhibited heightened risk of vitamin D insufficiency, while those with fair or very fair skin showed no deficiency.
A study found that paying for low-value vitamin D tests was stopped in Ontario, leading to a nearly 93% drop in testing. In contrast, US patients covered by Veterans Health benefits or commercial insurance saw only an 14% reduction after Choosing Wisely guidelines were issued.
A study found a significant association between low maternal vitamin D levels during early to mid-pregnancy and an increased risk of diagnosed attention-deficit/hyperactivity disorder (ADHD) in children. The research used the Finnish Maternity Cohort, which included 1,067 children with ADHD and their matched controls.
A new AI method combines incomplete medical datasets to spot causal relationships, allowing researchers to analyze expensive or difficult-to-run trials. The algorithm uses quantum cryptography-inspired principles to determine the most disordered variable as the cause.
A study of Danish women found a peak risk for hypertensive disorders in spring and summer, peaking midsummer. Vitamin D levels may explain the seasonal variation.
A six-month clinical trial found that higher doses of vitamin D supplementation reduced fasting blood glucose levels and improved insulin sensitivity in overweight, vitamin D-deficient children. However, the study did not show improvements in other cardiovascular health markers.
A large study published in the New England Journal of Medicine found that high doses of vitamin D do not reduce mortality or improve non-fatal outcomes in critically ill patients. The Vitamin D to Improve Outcomes by Leveraging Early Treatment (VIOLET) study included over 200 researchers and showed no difference in mortality rates, hos...
A 25-fold increase in UK children's vitamin D supplement prescriptions has been recorded, with high doses and no prior testing common. Most GPs fail to follow nationally set recommendations for vitamin D supplementation.
Recent expert reviews provide valuable updates on vitamin D's role in maternal health, rheumatoid arthritis, respiratory disease, and muscle. Key findings include the importance of routine vitamin D supplementation in childhood and pregnancy to support calcium metabolism.
Researchers found that first permanent molars carry life-long records of health information from the womb, storing vital data on Vitamin D intake and its impact on health. These 'living fossils' can provide clues connecting maternal health to a child's eventual fate.
A large clinical trial found that vitamin D and omega-3 fatty acid supplements did not slow the decline of kidney function in adults with Type 2 diabetes. The study involved over 1,300 participants and measured their kidney function over five years.
A large-scale trial found that vitamin D and omega-3 fatty acid supplements had no effect on reducing markers of systemic inflammation in older US adults. However, participants with low initial fish intake saw a decrease in inflammation biomarkers after taking the omega-3 supplement.
Researchers found vitamin D influences melanoma cells' behavior by slowing growth and reducing spread. This discovery could lead to new treatment approaches.
A new study found that skin UVB exposure increases gut microbial diversity and favors the growth of Lachnospiraceae bacteria, which are linked to vitamin D status. The results suggest a potential link between UVB light exposure and the protective effect against inflammatory diseases like MS and IBD.
Research from Trinity College Dublin shows that vitamin D deficiency is associated with poor skeletal muscle function in adults aged 60 years and over. Regular physical activity was found to be protective against impaired muscle strength and performance.
A recent University of Sheffield study found that taking vitamin D by oral spray is just as effective as taking a tablet in improving levels. The six-week trial compared the efficacy of vitamin D3 delivered through both capsule and sublingual methods, with results showing an equal rate of improvement in participants.
The VITamin D and OmegA-3 Trial (VITAL) found that Omega-3 fatty acids reduced heart attacks, while vitamin D supplementation lowered total cancer mortality among participants. The findings suggest a complex balance of benefits and risks for each intervention.
A new study reveals a strong association between vitamin D deficiency and increased mortality, particularly in younger and middle-aged individuals. Vitamin D levels of 10 nmol/L or less were associated with a 2-3 fold increase in risk of death, while levels above 90 nmol/L showed a 30-40% reduction in all-cause mortality.
Researchers discovered a dose-related decrease in bone density with high doses of vitamin D, contrary to initial predictions. Vitamin D supplementation above recommended levels (400-2000 IU daily) was not associated with an increase in bone density or strength.
Athletes who engage in outdoor sports and exercise are at increased risk of skin cancer, with up to eight-fold exposure limit exceeded during summer and autumn months. Sun protection is crucial for these groups, as research shows a higher incidence of malignant skin cancer among active individuals.
Researchers from Trinity College Dublin found that lower levels of specific vitamins and antioxidants are consistently associated with frailty in older adults. The study also suggests that micronutrient insufficiencies may act as an easily modified marker for frailty, offering new potential treatments.
A University of Michigan study found that children with vitamin D deficiency during elementary school were nearly twice as likely to develop externalizing behavior problems as those with higher levels. Low levels of the protein transporting vitamin D were also linked to self-reported aggressive behavior and anxious/depressed symptoms.
Researchers at the University of Birmingham found that fortifying wheat flour with vitamin D alone would save the public purse £65 million by reducing healthcare demands. Combining this with targeted supplementation could prevent 33% of cases, particularly among vulnerable groups.
Researchers at Rutgers University highlight the need for individualized vitamin D guidelines, as optimal levels may vary across ethnic and racial groups. Current tests have limitations, and more standardization efforts are being made to improve accuracy.
A recent analysis of clinical trials found that only a low-salt diet, omega-3 fatty acid supplements, and possibly folic acid supplements showed potential health benefits. The majority of supplements had no link to increased or decreased risk of death or heart health.
Research finds that low vitamin D levels from birth to early childhood are associated with an increased risk of elevated blood pressure later in life. Children born with vitamin D deficiency had a 60% higher risk of systolic hypertension between ages 6 and 18.
A recent study published in the Journal of Cachexia, Sarcopenia and Muscle found that vitamin D signaling is crucial for maintaining normal muscle size and strength. Researchers discovered that mice lacking vitamin D receptors in their muscle cells had smaller muscles and reduced physical performance.
Researchers at Martin-Luther-University Halle-Wittenberg have found a way to further increase the vitamin D content of eggs by exposing chickens to UV light. This method works under practical conditions and could represent an important step towards supplying the population with vitamin D.
A meta-analysis of 21 clinical trials involving 83,000 patients found no association between vitamin D supplementation and reduced risk of cardiovascular disease events such as heart attack or stroke. The study's results were consistent across different doses and genders.
A new Michigan State University study found that taking vitamin D supplements did not decrease the incidence of heart attacks, strokes or other major adverse cardiovascular events. The study of over 83,000 patients showed no benefit from vitamin D supplements in reducing cardiovascular risk.
The VITALE study found that high-dose vitamin D supplementation significantly reduces fracture risk in kidney transplant recipients, with a lower incidence of fractures in the high-dose group compared to the low-dose group. The treatment was well-tolerated with no increased risks of adverse effects.
A study published in Nutrients found that over half of adults aged 50+ have inadequate serum vitamin D levels, with 26% classified as deficient. Factors contributing to deficiency include female gender, advanced age, smoking, non-white ethnicity, obesity, and poor self-reported health.
Researchers found that sun-exposed oyster mushrooms can increase vitamin D levels and improve immunological responses in TB patients. The study used bread containing the mushrooms, which showed significant improvements in patients' TB severity scores and reduced vitamin D deficiency.
A large NIH-funded study found that taking a daily vitamin D supplement does not prevent type 2 diabetes in adults at high risk. The study, which enrolled over 2,400 participants, found no significant difference between those who took 4,000 IU of vitamin D and those who took a placebo.
A recent study found that taking vitamin D for at least three years may lower the risk of death among cancer patients. The researchers analyzed data from over 79,000 patients and discovered a statistically significant difference in mortality rates between those who took vitamin D and those who received a placebo.
A study published in the Journal of Perinatology found that pregnant black women with low vitamin D levels have higher levels of bacteria associated with preterm delivery. In contrast, white women with higher vitamin D levels had more lactobacilli, a type of bacteria that promotes vaginal health.
Researchers found that using high UVA protection factor sunscreen allows for better vitamin D synthesis due to increased UVB transmission. Despite concerns, optimal sunscreen use does not harm vitamin D production, according to a new study published in the British Journal of Dermatology.
Researchers found vitamin D affects dendritic cells' ability to activate T cells, hindering the activation process and reducing immune reactions. The study sheds light on how vitamin D deficiency may regulate the immune system and influence susceptibility to autoimmune diseases.
A small clinical trial suggests that high-dose vitamin D may delay disease progression in patients with metastatic colorectal cancer. Patients who received high-dose vitamin D had a median delay of 13 months before their disease worsened, compared to 11 months for those in the low-dose group.
A case study reveals that taking high doses of vitamin D can lead to kidney damage and malfunction. Patients should be better informed about the risks of using excessive amounts of vitamin D, particularly in low-risk individuals.