Articles tagged with Vitamin D
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A large randomized clinical trial involving over 18,000 participants found no significant benefit from vitamin D supplementation in preventing depression or improving mood. The study's results confirm longstanding questions about the effectiveness of vitamin D in reducing depression risk.
A study published in PLoS ONE found that inadequate calcium and vitamin D intake are prevalent among the US population, particularly those living below the poverty line. The research highlights the significant risk of osteoporosis for men and women from low-income backgrounds, with non-Hispanic Black men facing a two-fold increased risk.
A study of 782 COVID-19 positive and 7,025 negative patients found low plasma 25(OH)D levels to be an independent risk factor for COVID-19 infection and hospitalization. The association was strongest among older adults, with two peak age groups showing increased risk: 25 and 50 years old.
A new study found that vitamin D supplements reduced the risk of colitis by 65% in patients receiving immune checkpoint inhibitors for melanoma. The findings suggest that vitamin D supplementation could be a safe and cost-effective approach to preventing immunotherapy's gastrointestinal toxicity.
Researchers from the University of South Australia suggest that Vitamin D could mitigate chemotherapy-induced intestinal mucositis by suppressing inflammation and enhancing T-cell function. The study highlights the potential benefits of Vitamin D in reducing damage to the gut microbiome caused by chemotherapy agents.
A good vitamin D status is associated with a lower cancer risk, particularly in colon and blood cancers. Vitamin D responsiveness varies between individuals, affecting their need for supplementation.
A new study has found an association between low average levels of vitamin D and high numbers of COVID-19 cases and mortality rates across 20 European countries. Vitamin D modulates the response of white blood cells, preventing excessive inflammatory cytokine release, which is a key factor in COVID-19 severity.
A study of over 3,000 adults found that higher vitamin D intake from food sources was associated with lower rates of cardiovascular events, particularly in men. The researchers suggest that increased vitamin D consumption may protect against heart-related problems.
Researchers discovered genetic variants linked to vitamin D concentration and found that certain genes influence the body's ability to make vitamin D in response to sunlight. These findings provide new insights into how our bodies handle vitamin D and may help explain why low levels are associated with poor health.
Maintaining vitamin D receptor levels in pancreatic cells may protect against diabetes development and counteract cell damage. Researchers found that sustained VDR expression preserves β-cell mass and function, reducing inflammation and hyperglycemia.
A Rutgers-led study found that vitamin D levels greater than 12 nanograms per milliliter are associated with a higher rate of walking at 30 and 60 days after hip fracture surgery. Vitamin D deficiency is common in elderly patients with hip fractures, often occurring together with malnutrition.
A recent study published in Nutrients found that 65% of college basketball players were vitamin D insufficient at baseline. Athletes with darker skin pigmentation exhibited heightened risk of vitamin D insufficiency, while those with fair or very fair skin showed no deficiency.
A study found that paying for low-value vitamin D tests was stopped in Ontario, leading to a nearly 93% drop in testing. In contrast, US patients covered by Veterans Health benefits or commercial insurance saw only an 14% reduction after Choosing Wisely guidelines were issued.
A study found a significant association between low maternal vitamin D levels during early to mid-pregnancy and an increased risk of diagnosed attention-deficit/hyperactivity disorder (ADHD) in children. The research used the Finnish Maternity Cohort, which included 1,067 children with ADHD and their matched controls.
A new AI method combines incomplete medical datasets to spot causal relationships, allowing researchers to analyze expensive or difficult-to-run trials. The algorithm uses quantum cryptography-inspired principles to determine the most disordered variable as the cause.
A study of Danish women found a peak risk for hypertensive disorders in spring and summer, peaking midsummer. Vitamin D levels may explain the seasonal variation.
A six-month clinical trial found that higher doses of vitamin D supplementation reduced fasting blood glucose levels and improved insulin sensitivity in overweight, vitamin D-deficient children. However, the study did not show improvements in other cardiovascular health markers.
A large study published in the New England Journal of Medicine found that high doses of vitamin D do not reduce mortality or improve non-fatal outcomes in critically ill patients. The Vitamin D to Improve Outcomes by Leveraging Early Treatment (VIOLET) study included over 200 researchers and showed no difference in mortality rates, hos...
A 25-fold increase in UK children's vitamin D supplement prescriptions has been recorded, with high doses and no prior testing common. Most GPs fail to follow nationally set recommendations for vitamin D supplementation.
Recent expert reviews provide valuable updates on vitamin D's role in maternal health, rheumatoid arthritis, respiratory disease, and muscle. Key findings include the importance of routine vitamin D supplementation in childhood and pregnancy to support calcium metabolism.
Researchers found that first permanent molars carry life-long records of health information from the womb, storing vital data on Vitamin D intake and its impact on health. These 'living fossils' can provide clues connecting maternal health to a child's eventual fate.
A large clinical trial found that vitamin D and omega-3 fatty acid supplements did not slow the decline of kidney function in adults with Type 2 diabetes. The study involved over 1,300 participants and measured their kidney function over five years.
A large-scale trial found that vitamin D and omega-3 fatty acid supplements had no effect on reducing markers of systemic inflammation in older US adults. However, participants with low initial fish intake saw a decrease in inflammation biomarkers after taking the omega-3 supplement.
Researchers found vitamin D influences melanoma cells' behavior by slowing growth and reducing spread. This discovery could lead to new treatment approaches.
A new study found that skin UVB exposure increases gut microbial diversity and favors the growth of Lachnospiraceae bacteria, which are linked to vitamin D status. The results suggest a potential link between UVB light exposure and the protective effect against inflammatory diseases like MS and IBD.
Research from Trinity College Dublin shows that vitamin D deficiency is associated with poor skeletal muscle function in adults aged 60 years and over. Regular physical activity was found to be protective against impaired muscle strength and performance.
A recent University of Sheffield study found that taking vitamin D by oral spray is just as effective as taking a tablet in improving levels. The six-week trial compared the efficacy of vitamin D3 delivered through both capsule and sublingual methods, with results showing an equal rate of improvement in participants.
The VITamin D and OmegA-3 Trial (VITAL) found that Omega-3 fatty acids reduced heart attacks, while vitamin D supplementation lowered total cancer mortality among participants. The findings suggest a complex balance of benefits and risks for each intervention.
A new study reveals a strong association between vitamin D deficiency and increased mortality, particularly in younger and middle-aged individuals. Vitamin D levels of 10 nmol/L or less were associated with a 2-3 fold increase in risk of death, while levels above 90 nmol/L showed a 30-40% reduction in all-cause mortality.
Researchers discovered a dose-related decrease in bone density with high doses of vitamin D, contrary to initial predictions. Vitamin D supplementation above recommended levels (400-2000 IU daily) was not associated with an increase in bone density or strength.
Athletes who engage in outdoor sports and exercise are at increased risk of skin cancer, with up to eight-fold exposure limit exceeded during summer and autumn months. Sun protection is crucial for these groups, as research shows a higher incidence of malignant skin cancer among active individuals.
Researchers from Trinity College Dublin found that lower levels of specific vitamins and antioxidants are consistently associated with frailty in older adults. The study also suggests that micronutrient insufficiencies may act as an easily modified marker for frailty, offering new potential treatments.
A University of Michigan study found that children with vitamin D deficiency during elementary school were nearly twice as likely to develop externalizing behavior problems as those with higher levels. Low levels of the protein transporting vitamin D were also linked to self-reported aggressive behavior and anxious/depressed symptoms.
Researchers at the University of Birmingham found that fortifying wheat flour with vitamin D alone would save the public purse £65 million by reducing healthcare demands. Combining this with targeted supplementation could prevent 33% of cases, particularly among vulnerable groups.
Researchers at Rutgers University highlight the need for individualized vitamin D guidelines, as optimal levels may vary across ethnic and racial groups. Current tests have limitations, and more standardization efforts are being made to improve accuracy.
A recent analysis of clinical trials found that only a low-salt diet, omega-3 fatty acid supplements, and possibly folic acid supplements showed potential health benefits. The majority of supplements had no link to increased or decreased risk of death or heart health.
Research finds that low vitamin D levels from birth to early childhood are associated with an increased risk of elevated blood pressure later in life. Children born with vitamin D deficiency had a 60% higher risk of systolic hypertension between ages 6 and 18.
A recent study published in the Journal of Cachexia, Sarcopenia and Muscle found that vitamin D signaling is crucial for maintaining normal muscle size and strength. Researchers discovered that mice lacking vitamin D receptors in their muscle cells had smaller muscles and reduced physical performance.
Researchers at Martin-Luther-University Halle-Wittenberg have found a way to further increase the vitamin D content of eggs by exposing chickens to UV light. This method works under practical conditions and could represent an important step towards supplying the population with vitamin D.
A new Michigan State University study found that taking vitamin D supplements did not decrease the incidence of heart attacks, strokes or other major adverse cardiovascular events. The study of over 83,000 patients showed no benefit from vitamin D supplements in reducing cardiovascular risk.
A meta-analysis of 21 clinical trials involving 83,000 patients found no association between vitamin D supplementation and reduced risk of cardiovascular disease events such as heart attack or stroke. The study's results were consistent across different doses and genders.
The VITALE study found that high-dose vitamin D supplementation significantly reduces fracture risk in kidney transplant recipients, with a lower incidence of fractures in the high-dose group compared to the low-dose group. The treatment was well-tolerated with no increased risks of adverse effects.
A study published in Nutrients found that over half of adults aged 50+ have inadequate serum vitamin D levels, with 26% classified as deficient. Factors contributing to deficiency include female gender, advanced age, smoking, non-white ethnicity, obesity, and poor self-reported health.
Researchers found that sun-exposed oyster mushrooms can increase vitamin D levels and improve immunological responses in TB patients. The study used bread containing the mushrooms, which showed significant improvements in patients' TB severity scores and reduced vitamin D deficiency.
A large NIH-funded study found that taking a daily vitamin D supplement does not prevent type 2 diabetes in adults at high risk. The study, which enrolled over 2,400 participants, found no significant difference between those who took 4,000 IU of vitamin D and those who took a placebo.
A recent study found that taking vitamin D for at least three years may lower the risk of death among cancer patients. The researchers analyzed data from over 79,000 patients and discovered a statistically significant difference in mortality rates between those who took vitamin D and those who received a placebo.
A study published in the Journal of Perinatology found that pregnant black women with low vitamin D levels have higher levels of bacteria associated with preterm delivery. In contrast, white women with higher vitamin D levels had more lactobacilli, a type of bacteria that promotes vaginal health.
Researchers found that using high UVA protection factor sunscreen allows for better vitamin D synthesis due to increased UVB transmission. Despite concerns, optimal sunscreen use does not harm vitamin D production, according to a new study published in the British Journal of Dermatology.
Researchers found vitamin D affects dendritic cells' ability to activate T cells, hindering the activation process and reducing immune reactions. The study sheds light on how vitamin D deficiency may regulate the immune system and influence susceptibility to autoimmune diseases.
A small clinical trial suggests that high-dose vitamin D may delay disease progression in patients with metastatic colorectal cancer. Patients who received high-dose vitamin D had a median delay of 13 months before their disease worsened, compared to 11 months for those in the low-dose group.
A case study reveals that taking high doses of vitamin D can lead to kidney damage and malfunction. Patients should be better informed about the risks of using excessive amounts of vitamin D, particularly in low-risk individuals.
A new clinical trial found that burosumab significantly improves rickets and related outcomes in children with X-linked hypophosphatemia compared to conventional therapy. The study, which included 61 children, showed substantial healing of rickets in 72% of participants who received burosumab.
A Rutgers-led study found that higher doses of vitamin D improved memory and learning, but slowed reaction times among post-menopausal women. The researchers warn that excessive doses may compromise balance and walking ability, increasing the risk of falls.
A randomized clinical trial found no association between high-dose vitamin D supplementation during pregnancy and the risk of asthma in children at age 6. The study followed 545 children whose mothers received either high-dose or standard-dose vitamin D supplementation.
A recent study found that vitamin D levels can modify the response to indoor air pollution in obese urban children with asthma. The research team identified a significant link between low blood vitamin D levels and respiratory problems, as well as an inverse relationship between high blood vitamin D levels and asthma symptoms.
A survey of 91 different multivitamins and vitamin D supplements for children in the UK found that many do not provide the recommended daily dose of 400 IU of vitamin D. Only one multivitamin was suitable for use from birth, while between a quarter and a third of available products supplied at least 400 IU/day for children over 6 months.
Researchers from Trinity College Dublin and St James's Hospital successfully measured vitamin D in human hair, a major step forward in assessing vitamin D status. This could provide a longer-term record of an individual's vitamin D levels, potentially allowing for better strategies to maintain stable concentrations.
A new study confirms that obesity impairs vitamin D conversion in the liver, affecting its major form in the blood. This finding highlights the need for targeted treatment approaches, such as calcidiol, to address vitamin D insufficiency in obese individuals.
Research at University of Queensland suggests a connection between vitamin D levels and brain structure, finding that low levels disrupt perineuronal nets in the hippocampus. This disruption leads to reduced cognitive function and potentially contributes to disorders like depression and schizophrenia.
Researchers at Kobe University found that vitamin D signaling fuels the growth of macrophages in bone marrow, leading to myelofibrosis and bone hardening. A low-vitamin D diet can prevent or treat the condition.