Articles tagged with Vitamin D
Researchers found vitamin D affects dendritic cells' ability to activate T cells, hindering the activation process and reducing immune reactions. The study sheds light on how vitamin D deficiency may regulate the immune system and influence susceptibility to autoimmune diseases.
A small clinical trial suggests that high-dose vitamin D may delay disease progression in patients with metastatic colorectal cancer. Patients who received high-dose vitamin D had a median delay of 13 months before their disease worsened, compared to 11 months for those in the low-dose group.
A case study reveals that taking high doses of vitamin D can lead to kidney damage and malfunction. Patients should be better informed about the risks of using excessive amounts of vitamin D, particularly in low-risk individuals.
A new clinical trial found that burosumab significantly improves rickets and related outcomes in children with X-linked hypophosphatemia compared to conventional therapy. The study, which included 61 children, showed substantial healing of rickets in 72% of participants who received burosumab.
A Rutgers-led study found that higher doses of vitamin D improved memory and learning, but slowed reaction times among post-menopausal women. The researchers warn that excessive doses may compromise balance and walking ability, increasing the risk of falls.
A randomized clinical trial found no association between high-dose vitamin D supplementation during pregnancy and the risk of asthma in children at age 6. The study followed 545 children whose mothers received either high-dose or standard-dose vitamin D supplementation.
A recent study found that vitamin D levels can modify the response to indoor air pollution in obese urban children with asthma. The research team identified a significant link between low blood vitamin D levels and respiratory problems, as well as an inverse relationship between high blood vitamin D levels and asthma symptoms.
A survey of 91 different multivitamins and vitamin D supplements for children in the UK found that many do not provide the recommended daily dose of 400 IU of vitamin D. Only one multivitamin was suitable for use from birth, while between a quarter and a third of available products supplied at least 400 IU/day for children over 6 months.
Researchers from Trinity College Dublin and St James's Hospital successfully measured vitamin D in human hair, a major step forward in assessing vitamin D status. This could provide a longer-term record of an individual's vitamin D levels, potentially allowing for better strategies to maintain stable concentrations.
A new study confirms that obesity impairs vitamin D conversion in the liver, affecting its major form in the blood. This finding highlights the need for targeted treatment approaches, such as calcidiol, to address vitamin D insufficiency in obese individuals.
Research at University of Queensland suggests a connection between vitamin D levels and brain structure, finding that low levels disrupt perineuronal nets in the hippocampus. This disruption leads to reduced cognitive function and potentially contributes to disorders like depression and schizophrenia.
Researchers at Kobe University found that vitamin D signaling fuels the growth of macrophages in bone marrow, leading to myelofibrosis and bone hardening. A low-vitamin D diet can prevent or treat the condition.
A study of 1,850 patients with multi-drug resistant tuberculosis found that vitamin D supplementation accelerated TB clearance in those receiving antibiotic treatment. The findings suggest a potential host-directed therapy to improve outcomes for patients with drug-resistant bacterial infections.
A new study published in the American Journal of Clinical Nutrition found that vitamin D supplements have no significant impact on bone mineral density or falls among older adults. However, higher doses may improve bone metabolism and be safe for those over 70.
A study led by Queen Mary University of London found that vitamin D supplements reduced the risk of potentially fatal lung attacks in COPD patients with low vitamin D levels. The use of supplements led to a significant reduction in moderate/severe exacerbations, with no benefit seen for patients with higher vitamin D levels.
A randomized trial by Vanderbilt University Medical Center researchers found that magnesium boosts vitamin D status in people with low levels and reduces it in those with high levels. The ideal level of vitamin D is believed to be within the middle range of a U-shape, linked to the lowest risk of cardiovascular disease.
A recent study found that treatment with active vitamin D did not decrease cardiovascular events in patients undergoing hemodialysis. Researchers tested oral alfacalcidol, an active form of vitamin D, to see if it improved clinical outcomes. The results showed no significant benefit for patients without secondary hyperparathyroidism.
Researchers from Aarhus University and the University of Queensland found that newborns with vitamin D deficiency had a 44% increased risk of being diagnosed with schizophrenia as adults. The study suggests that ensuring pregnant women have adequate levels of vitamin D may result in the prevention of some schizophrenia cases.
A study by researchers at the University of Queensland found that newborns with vitamin D deficiency had a 44% increased risk of being diagnosed with schizophrenia as adults. Ensuring pregnant women have adequate levels of vitamin D may result in the prevention of some schizophrenia cases.
A new study from Trinity College Dublin found that vitamin D deficiency is associated with a substantial increase in depression risk among older Irish adults. The study followed participants over four years and found a 75% higher risk of developing depression, even after controlling for other factors.
Researchers discovered vitamin D is essential for embryonic development and dormancy in fish, a trait conserved across species. This finding could lead to better understanding of dormancy mechanisms and their applications in human health.
The VITAL study found that omega-3 fatty acids reduced the risk of heart attacks, particularly among African American participants. Vitamin D supplements may also lower cancer deaths over time, with a significant 25% reduction in mortality rates observed after two years of treatment.
A study published in the European Journal of Preventive Cardiology found that higher vitamin D levels are associated with better exercise capacity and cardiorespiratory fitness. Participants with higher vitamin D levels had a 4.3-fold higher fitness level compared to those with lower levels.
Researchers have developed personalized and low-cost wearable ultraviolet sensors that warn users of dangerous UV exposure. The paper-based sensor features color-changing emoticon faces, indicating the user's daily recommended UV exposure percentage.
A large meta-analysis of 81 randomised trials found no effect of vitamin D supplementation on bone mineral density, fractures, or falls in adults. The study suggests that clinical guidelines should be changed to reflect the best available evidence and that there is little justification for using vitamin D supplements for musculoskeleta...
A new study found that low vitamin D levels are associated with a 77% higher risk of death in community-dwelling Thai older men. The risk is significant only in diabetic males, suggesting cardiovascular disease may be the link.
A study of 232 obese children found that vitamin D supplementation led to significant reductions in body mass index and body fat. This suggests a potential role for vitamin D in reducing the risk of serious health problems, such as heart disease and diabetes, later in life.
A study published in the Journal of Behavioral Medicine found that women with shorter days during late pregnancy may be at a higher risk of developing postpartum depression. Exposure to natural light and vitamin D can help alleviate symptoms.
RMIT researchers develop color-changing sensors to measure individual UV exposure, providing a simple solution to prevent Vitamin D deficiency and sunburn. The technology has potential applications beyond health, improving safety and reliability in various industries.
Researchers have identified cocoa as a new source of vitamin D2, found in higher amounts in dark chocolate. Vitamin D2 is crucial for the human body and can be obtained through food sources, reducing the risk of deficiencies.
A recent genome-wide association study found that only two factors - bone mineral density and muscle strength - contribute to fracture risk, while vitamin D levels do not directly predispose people to fractures. Increasing bone strength is more effective in preventing fractures than widespread vitamin D supplementation.
A large international collaboration identified 15 genetic variations linked to bone fracture risk, contradicting previous assumptions about clinical risk factors. The study highlights the importance of increasing bone strength in preventing fractures, rather than relying solely on calcium and vitamin D supplementation.
Researchers found that genetic variation was the only factor associated with increased fracture risk, while vitamin D levels and calcium intake were not linked. Bone mineral density remained a key predictor of fracture risk.
A randomized clinical trial found that monthly high-dose vitamin D supplementation without calcium did not reduce cancer risk among adults. The study analyzed data from 2,558 participants who received the supplement and 2,550 participants in a placebo group.
A new clinical trial will assess the impact of high-dose omega-3 fatty acids and vitamin D supplementation on halting type 1 diabetes progression. The POSEIDON Study aims to reduce inflammation, increase insulin secretion, and promote a potential cure for this autoimmune disease.
Researchers from the University of Adelaide conducted a systematic review of over 70 studies on vitamin D's role in neurodegenerative diseases, including multiple sclerosis, Parkinson's disease, and Alzheimer's disease. The findings suggest that vitamin D is unlikely to protect against these brain-related disorders.
A major study found that one in three pregnant women in Norway has a vitamin D deficiency at the end of their pregnancy. Low levels can affect bone health and increase the risk of asthma in children. The study suggests that small measures, such as taking supplements and eating fish, can have positive effects on vitamin D levels.
Researchers highlight tragic case of baby Noah's death due to vitamin D deficiency and advocate for simplified guidance, mandatory monitoring, and food fortification. Current UK recommendations are deemed outdated and overly complex, putting dark-skinned individuals at risk.
A new study finds low intakes of vitamin D among UK South Asian adults due to inadequate dietary intake and low supplementation rates. The population group is at increased risk of chronic diseases like osteoporosis, cancer, and cardiovascular disease.
Researchers found no evidence that vitamin D levels are associated with a reduced risk of gestational hypertension or pre-eclampsia. However, low vitamin D levels during pregnancy can increase the risk of these conditions by suppressing blood pressure-regulating hormones. Further studies are needed to confirm the findings.
A new review suggests that vitamin D may play an integral part in the induction and regulation of critical immune tolerance in early pregnancy. Vitamin D deficiency has been linked to increased risk of recurrent pregnancy loss.
Researchers found that lower than normal blood levels of vitamin D were associated with an increased risk of early signs of interstitial lung disease, a condition that can lead to progressive lung damage. Vitamin D deficiency was linked to larger volumes of damaged lung tissue and abnormalities on full lung scans.
Researchers found that women with higher vitamin D levels in their blood had a significantly reduced risk of developing breast cancer. The study, which pooled data from multiple trials and prospective studies, identified the minimum healthy level of vitamin D as 60 nanograms per milliliter.
A new study has found that girls with high vitamin D levels have stronger muscles than those with low levels. The association was not found in boys, and researchers are unsure why girls benefit more from vitamin D. Vitamin D is an important source of muscle strength, but the exact mechanism is still unclear.
A large international study found that higher circulating vitamin D concentrations are significantly associated with lower colorectal cancer risk. Optimal vitamin D concentrations for colorectal cancer prevention may be higher than current recommendations.
Research from the University of Eastern Finland found a link between higher serum vitamin D levels and lower plasma cholesterol levels in primary school children. Children with sufficient vitamin D levels had lower total and LDL cholesterol levels compared to those with insufficient levels.
Women with insufficient vitamin D levels before pregnancy were more likely to experience miscarriage compared to those with sufficient levels. Vitamin D was found to play a protective role in maintaining pregnancy.
Two studies investigate vitamin D supplementation's impact on infant development, with no significant difference found in bone strength or infection incidence at age 24 months. A systematic review and meta-analysis also explores the effects of prenatal vitamin D on several infant outcomes.
A randomized clinical trial found that sustained vitamin D supplementation reduced the likelihood of recurrent wheezing in preterm black infants by 12 months' adjusted age. The study involved 300 black infants born between 28-36 weeks and compared two vitamin D supplementation strategies.
African American preterm infants experienced a significant decrease in recurrent wheezing with sustained vitamin D supplementation, according to a new study published in JAMA. The daily dose of vitamin D through six months of age decreased recurrent wheezing by more than 10%.
Obese individuals with larger waistlines are at a greater risk of developing vitamin D deficiency. The study found that lower levels of belly fat were associated with lower vitamin D levels in both men and women.
A recent study found that UK children with non-alcoholic fatty liver disease have insufficient vitamin D levels throughout the year, particularly during winter months. Genetic variations in the vitamin D metabolic pathway are also associated with increased liver fat and inflammation.
Researchers at Salk Institute report a potential new approach for treating diabetes by protecting beta cells with vitamin D. The study identified a compound that enhances the activation of the vitamin D receptor, leading to improved survival of beta cells and normal glucose levels in mice.
A study led by Queen Mary University of London found that high-dose vitamin D supplements significantly boosted weight gain in malnourished children. Vitamin D supplementation also resulted in substantial reductions in delayed motor development and language development, with potential implications for the management of severe acute mal...
A study of 32 children under 10 found significant DNA damage from small amounts of sun exposure, similar to levels in Danish adults. Parents are advised to use rigorous protection measures and consider vitamin D supplements.
Researchers found genetic adaptation for low UV exposure in North and East Asian populations, linked to increased sweat gland density and mammary ductal branching. The EDAR V370A variant may have selected for improved vitamin D biosynthesis through breast milk, enhancing offspring nutrition.
A genetic mutation that increased mammary duct branching may have provided more vitamin D to infants, helping them survive in the far north. Shovel-shaped incisors became more frequent among Native Americans due to the same genetic factor, highlighting the importance of the mother-infant bond.
Researchers found that vitamin D levels above 30 ng/ml reduced diabetes risk by one-third and those above 50 ng/ml had a one-fifth risk reduction. Vitamin D deficiency was linked to a greater risk of developing diabetes, with persons at up to five times higher risk than those with optimal levels.
The USPSTF recommends against daily supplementation with vitamin D and calcium to prevent fractures in men and premenopausal women. However, they suggest these supplements may be beneficial for postmenopausal women, as current scientific evidence is insufficient for the general population.
The USPSTF recommends exercise interventions to prevent falls in adults 65 years and older, with moderate evidence supporting this approach. Multi-factorial interventions targeting balance, gait, vision, medication use, and other risk factors are also recommended.