Researchers analyzed sediment cores from Horseshoe Lake adjacent to Cahokia settlement, finding a correlation between climate shifts and population decline. Climate changes, including decreased summer precipitation and flooding, stressed Cahokia's agricultural system, contributing to its depopulation.
The study reveals that Foxp1 is essential for the proper functioning of Treg cells, which play a crucial role in regulating immune responses. The findings suggest that targeting Foxp1 could lead to the development of therapies that selectively modulate Treg cell activity, offering new hope for treating autoimmune diseases and cancer.
Patients living with HIV have equal access to optimal cancer therapy, according to a recent study in the journal CANCER. The findings challenge traditional beliefs that HIV infection is a contraindication for intensive cancer treatment.
New research finds humans struggle to accurately classify snail shells due to differences in colour perception. A study using spectrometry reveals distinct clusters for brown, pink, and yellow snails, providing a baseline measure for future studies on animal colour and genetics.
Researchers used over 1,000 records and a global ecosystem model to reconstruct peatland dynamics. They found peatlands expanded during warm periods and were buried during glacial expansion, providing potential long-term carbon storage.
Research finds that people who believe in conspiracy theories are more likely to engage in low-level crime, such as fraud and theft. The study suggests that this behavior is linked to a feeling of social disconnection and lack of shared values.
Researchers at DESY achieved a world record in plasma acceleration using a laser drill, accelerating electrons to an energy of 7.8 billion electron volts. The technique uses a laser pulse to drill through a plasma, confining the beam and enabling the acceleration of particles hundreds of times stronger than conventional accelerators.
Tropical Cyclone Wutip strengthened into a powerful super typhoon, with NASA-NOAA's Suomi NPP satellite capturing a clear eye 25 nautical miles wide. The storm is expected to weaken due to an eyewall replacement cycle and increased vertical wind shear.
Researchers at U of T Engineering created a 3D hydrogel to mimic lung cancer environments, selectively allowing cancer cells to invade. This technology enables rapid screening of hundreds of potential drugs for their ability to fight invasive cancers.
Researchers discovered 139 new genetic differences affecting lung health and COPD risk, showing both smokers and non-smokers can develop the disease. These findings could lead to new treatments for COPD, impacting global health.
Researchers found that icefish have evolved transparent blood, increased energy production, and specialized proteins to protect against cold damage. These adaptations enable them to thrive in Antarctica's frigid waters.
A special issue of WORK: A Journal of Prevention, Assessment & Rehabilitation explores the dynamics between work and pain. The study found that presenteeism, repetitive work, and job stress are linked to chronic pain, with psychological symptoms intensifying physical ones.
Researchers document a new 'behavioral realm' in Eastern chimpanzees of the Bili-Uéré region, characterized by novel tool use and expanded food processing technologies. This discovery sheds light on the likely incipient traditions of early hominin ancestors and highlights the importance of studying intact ape cultures.
Scientists at the University of British Columbia have discovered a new protein 'switch' that can stop the progression of sepsis, a life-threatening disease. This discovery could lead to new treatments for chronic and acute inflammatory diseases.
Researchers found that tree growth is constrained more by climate than competition for resources in harsh conditions, but not under mild conditions. The study provides important insights into how forest growth will respond to changing climate and could inform land management strategies.
Researchers at MIT have developed a way to measure oxygen levels of pancreatic islet cells over long periods, enabling them to predict which implants will be most effective in treating diabetes. This breakthrough could lead to better designs for artificial pancreas systems.
Red alder trees have been found to tap nutrients from bedrock through their symbiotic relationship with nitrogen-fixing bacteria. This process accelerates rock dissolution, releasing mineral nutrients that allow plants and trees to grow. The study highlights the importance of nitrogen-fixing trees in sustaining forest ecosystems.
Researchers found fire, forest disturbances, and soil erosion decreased in the 14th century, indicating a gradual decline in land-use intensity. The moat was covered with floating vegetation by the end of the 14th century, indicating it was no longer maintained.
A study by Joep Schyns et al. estimates limits to green water availability due to limited annual rainfall, affecting global food and production systems. The analysis reveals that green water scarcity is a significant concern, particularly in regions with low rainfall.
A new study from Duke University reveals that patient savers quickly choose the higher amount, screening out irrelevant factors, and making decisions with minimal analysis. The research aims to provide strategies for improving financial literacy and promoting savings.
A team of engineers at Washington University in St. Louis developed a high-power fuel cell that operates at double the voltage of commercial fuel cells, powering unmanned underwater vehicles, drones, and eventually electric aircraft at significantly lower cost.
A recent Ohio University study found that American hospitals have seen a decline in opioid abuse treatment programs, despite the growing opioid epidemic. The study analyzed data from 3,365 acute-care hospitals and found that many hospitals dropped these programs between 2010 and 2015.
Birds have on average advanced their spring migration by a little over a week since the late 1950s, with some species arriving two weeks earlier than in the 1980s.
A Danish study of 943,027 individuals found that growing up in areas with abundant vegetation was associated with a lower risk of developing psychiatric disorders. The findings suggest that incorporating natural environments into urban spaces can improve the mental health of urban residents.
Researchers at UMass Amherst have discovered a novel therapeutic target, CYP monooxygenase pathway, that could prevent or treat colon cancer. The study found that certain fatty acid metabolites, such as epoxyoctadecenoic acids (EpOMEs), increase inflammation and tumor growth in the colon.
A recent study published in Obesity found that consuming red raspberries can lower blood glucose levels and improve insulin responses in individuals at risk for diabetes. The researchers concluded that incorporating certain fruits like red raspberries into meals can have beneficial effects on glucose control.
The study found that men aged 15-54 years and women aged 15-49 years exposed to the ICDS program during their first three years of life completed 0.1-0.3 more grades of schooling than those not exposed. This significant long-term benefit highlights the importance of early-life interventions in improving educational outcomes.
Researchers discovered that plants' built-in drought detection system has an unlikely origin: freshwater-dwelling streptophyte algae. This signaling pathway, which triggers plants' drought defenses, has remained virtually unchanged for hundreds of millions of years and exists across most plant lineages.
A pioneering educational programme aims to reduce the risk of falls in children by teaching safe and protective techniques, simulating falls in PE classes. The programme responds to WHO demands and has been shown effective in schools, with interest from universities worldwide.
A non-native species of wasp, the samurai wasp, has been identified in British Columbia, Canada, prior to formal approval for its introduction. The wasp is a natural parasitoid of the brown marmorated stink bug, a globally spreading agricultural pest native to Asia.
A new study published in Obesity found that successful weight losers spent an average of just 14.6 minutes per day on dietary self-monitoring, confirming the reality of its effectiveness rather than the perceived time-consuming nature. The most predictive factor was logging in three or more times a day with consistency.
Researchers create a unique platform to study quantum optical physics on the nanoscale by stacking 2D materials at angles to trap particles. The team successfully traps hundreds of excitons using a moiré pattern, which can be controlled by a twist, enabling precise manipulation and interaction with individual excitons.
Researchers found that a single dose of PD-1 inhibitor before surgery can lead to complete remission and cancer-free follow-up for more than two years. Immune responses from this therapy can peak within seven days, allowing for earlier guidance on the most effective treatment approach.
Scientists have developed a microscopy method that directly observes bacterial filaments, revealing a new mechanism by which bacteria interact with surfaces. The study shows that type IV pili movements are coordinated through sequential control of pilus extension and retraction, enabling efficient movement across surfaces.
A study examines how costume changes in Star Wars female leads Padmé and Leia parallel shifts in their positions of power and romantic relationships. The researchers argue that these changes contribute to the objectification of women through costume design, highlighting the importance of considering the portrayal of women in media.
Research suggests that childhood affluence may hinder cognitive development in adulthood, as those with the most advantageous conditions experience stronger cognitive decline over time. This study analyzed data from 24,066 individuals and found a paradoxical relationship between socioeconomic status and cognitive aging.
Researchers found that evacuees who returned to their homes after initial evacuation had more children, while those who stayed in western Finland had fewer. Those who intermarried with the host population increased their social status, but were less likely to have children.
Research led by University of East Anglia finds that policies supporting renewable energy and energy efficiency are helping reduce CO2 emissions in 18 developed economies. The study suggests that these efforts need to be expanded and enhanced to limit climate change.
Researchers discovered a novel mechanism for high-quality optical resonators by exploiting the mutual destructive interference of two low-quality optical states. This allows for secure light trapping in various materials at small scales, enabling the creation of compact devices like sensors and filters.
Researchers debunked a common misconception that millions of people have an antibiotic allergy. Studies show that only 10% of reported allergies are true, and many lose their allergy over time.
Researchers found that lung cancer cells acquire resistance to molecular-targeted drugs by transforming epithelial characteristics into mesenchymal ones, leading to reduced miR-200c expression. Sequential treatment with an HDAC inhibitor and a next generation molecular-targeted drug overcomes this resistance, offering new potential for...
The proliferation of genetically modified seeds in India has led to 'choice overload,' where farmers struggle to make decisions due to a vast array of options. Farmers prioritize community expectations and social status over yield, driven by the desire to be successful and modern.
Researchers found that blue whales align their migration timing with historical averages of krill production, rather than responding to current prey patches. This suggests that blue whales rely on memory to locate stable, high-quality foraging sites, which could make adaptation to climate change more difficult.
Researchers at Penn Medicine have successfully cured nine patients of Hepatitis C after receiving heart transplants from deceased donors who were infected with the disease. The study suggests that using HCV-infected organs may be a viable option for patients awaiting a heart transplant.
The National Foundation for Cancer Research (NFCR) has launched the Salisbury Award, a new program aimed at supporting translational cancer research. The award will provide funding and resources to researchers with early-stage projects deemed to have the best combination of novel and impactful technology.
A new study suggests that high CO2 levels above 1,200 ppm could lead to the loss of low-level clouds, resulting in a 8-Kelvin temperature increase globally. The researchers used a small-scale model to simulate cloud instability and found that once the clouds vanish, they do not reappear until CO2 levels drop significantly.
A new study published in Aging Clinical and Experimental Research found that high health literacy can be a resource in old age, leading to better physical functioning, fewer illnesses, and improved health ratings. The study also highlighted the importance of evaluating media health information's reliability.
The study reveals that only one amino acid residue plays a critical role in cleavage function for prokaryotic Ago, whereas its counterpart in eukaryotes has multiple roles. The discovery sheds light on how the cleavage functions evolve from prokaryotes to eukaryotes.
Researchers challenge decades-old research on emotional intelligence, finding that context is crucial for reading emotions. Study participants accurately identified characters' emotions from background and interactions, not just facial expressions.
A study of 2,700 patients with ADHD found that variations in the LPHN3 gene increased the risk of nicotine dependence by 40%. The findings suggest a link between ADHD and addictive substance use, highlighting the need for new genetic tools to prevent addictive behaviors in people with ADHD.
Researchers have identified specific brain cell types, areas and biological processes linked to the genetic risk of insomnia, a major step towards understanding its mechanisms. The study found that over 100 genes contribute to insomnia, with some influencing the functionality of axons and specific cell types in the frontal cortex.
Researchers investigate opioid receptors' effect on cardioprotection against coronary disease and find that certain subtypes have a special role in adapting to oxygen lack. The study suggests new targets for developing ischemia prevention drugs, with promising results.
Scientists at The University of Toledo found that insects manipulate grape vines' reproductive programs to create a leaf gall, providing a protected space for the parasite. This discovery opens possibilities for protecting wine and raisin production from agricultural pests.
Neurons in both males and females produce estrogen, which is essential for synaptic plasticity and memory. Research shows that mice lacking estrogen have impaired spatial reference memory and recognition memory.
A new study shows that banded mongoose pups who receive consistent care in their first three months of life have a life-long advantage, including increased fitness and reproductive success. This 'silver spoon effect' is particularly beneficial for female pups, with more care leading to higher reproductive success.
Researchers have discovered evidence of significant ocean oxygenation before the Great Oxidation Event (GOE), which occurred around 2.5 billion years ago. This finding challenges previous understanding of oxygen accumulation, suggesting it may have extended over large regions of the ocean and even reached the sea floor.
A new study from the University of Copenhagen has identified a key mechanism behind the repair of human DNA damage, which can lead to cancer. The researchers have discovered a protein called BARD1 that acts like a 'scanner' to launch the flawless DNA repair system.
A Canadian study found that mothers whose first child was taken into out-of-home care were more likely to have inadequate or no prenatal care during subsequent pregnancies. These women are also more likely to face barriers such as substance use disorders and poverty, highlighting the need for accessible and nonjudgmental prenatal care.
The XMaS facility will receive a £7.2million upgrade to enhance its capabilities for studying materials' atomic and microscopic structures. This will support research into various fields, including energy storage, climate change, and healthcare.
A study using Twitter data found that people tweet more about unusual temperatures, but comment less when those temperatures recur. The study suggests that major warming from climate change may not be perceived as remarkable due to a rapidly adjusting normal baseline.