Cell Growth
Articles tagged with Cell Growth
Plants pause, play and fast forward growth depending on types of climate stress
Researchers at the University of British Columbia have identified genes and pathways responsible for plant recovery from environmental stress, including cold snaps and flooding. This discovery could lead to the creation of climate-resilient crops that can recover faster and more efficiently after climate events.
Galvanizing blood vessel cells to expand for organ transplantation
Researchers at Weill Cornell Medicine develop a new method to generate functional endothelial cells from adult tissue, potentially enabling vascular grafts and organ transplants. The approach involves using small molecules to trigger cell division without aging or losing function.
Evaluating the effect of liquid-handling speed on yeast growth using robots
Researchers investigated pipetting speed's effect on yeast growth and gene expression, finding it had little to no impact within a tested range. The study provides guidelines for increasing efficiency and reproducibility in robot-based experiments.
3D cell cultures provide new insights on lung cancer treatment response
Researchers have developed three-dimensional spheroid cultures that better replicate cell-cell interactions and nutrient gradients, leading to a greater understanding of tumour tissue behaviour and drug responses. The study highlights the importance of mimicking tumour architecture in testing cancer therapies.
Cell colonies under pressure – how growth can prevent motion
Research at Max Planck Institute for Dynamics and Self-Organization explores how growth impacts cell migration. The study reveals a critical threshold of motility above which colony growth inhibits cellular movement, with implications for biology, tissue engineering, and medical research.
University of Cincinnati Cancer Center presents research at AACR 2025
Researchers from the University of Cincinnati Cancer Center presented abstracts highlighting contrasting effects of a protein on head and neck, breast, and lung cancers. The study found increased levels of IL-9 in patients with head and neck cancer correlated with decreased survival, while elevated IL-9 was associated with smaller tumo...
Toxic blooms in motion: Researchers map algae patterns in Lake Okeechobee
A new study maps the daily movement of cyanobacteria in Florida's largest freshwater lake, revealing how these harmful algal blooms form and behave. The research provides critical insights into managing the risks associated with cyanobacteria blooms.
Tumor byproduct blocks immune cells from fighting cancer
A team of researchers has identified a novel oncometabolite that accumulates in tumors and impairs immune cells' ability to fight cancer. The study highlights how the metabolic environment of tumors influences T cell function, opening new possibilities for improving cancer immunotherapy by targeting tumor metabolism.
Dancing with the cells – how acoustically levitating a diamond led to a breakthrough in biotech automation
Engineers at University of Bristol spin-out company Impulsonics have created a technology that can move cells using acoustic waves, enabling critical lab tasks to be carried out on a benchtop device. This innovation has the potential to accelerate drug discovery and unlock personalized medicine screening in clinics.
Nature’s viny vampire: Discovering what drives parasitic Cuscuta campestris
Researchers at Osaka Metropolitan University identified the CcMCA1 gene as a key player in the development of haustoria, structures that allow Cuscuta campestris to feed on host plants. Suppressing this gene expression can reduce the number of haustoria per centimeter, offering potential for controlling invasive plant species.
Why some breast cancer treatments stop working
A new review highlights how breast cancer cells change their communication and growth patterns, helping tumors survive, spread, and resist treatment. The review explores disrupted signaling pathways, including PI3K/Akt/mTOR and RAS/RAF/MEK/ERK, which can promote tumor progression and resistance to treatment.
MIT scientists engineer starfish cells to shape-shift in response to light
Researchers at MIT successfully triggered a key enzyme in starfish egg cells using different patterns of light, prompting predictable movements and contractions. The study provides a new optical tool for controlling cell shape in its earliest developmental stages.
Scientists discover protein key to bacteria’s survival in extreme environments
Researchers have discovered a protein called MdfA that enables bacteria to shut down into dormant spores under extreme conditions. This process allows bacteria to survive in uninhabitable places and evade hospital cleaning, making them potentially deadly superbugs.
New antibody reduces tumor growth in treatment-resistant breast and ovarian cancers
A new type of antibody that stimulates the immune system to target cancer cells has shown promise in reducing tumor growth in treatment-resistant breast and ovarian cancers. The study found that the antibody, IgE, uniquely stimulated otherwise inactive immune cells to directly target HER2-expressing cancer cells.
New insights into plant growth
A recent study revealed that brassinosteroids are distributed unevenly between new cells formed during cell division, influencing root growth and development. The findings provide a comprehensive understanding of how these hormones regulate plant growth and development at the cellular level.
Bringing expansion microscopy to plants
Researchers have developed ExPOSE, a method that allows for the visualization of plant cells with greater resolution, enabling studies on protein and RNA location, and cellular response. The technique uses protoplasts to overcome cell wall challenges, paving the way for a powerful new toolkit in plant biology.
Antimicrobial resistance in soil bacteria without the use of antibiotics
A study found that soil bacterial communities show increased antimicrobial resistance due to the presence of a predatory bacterium, Myxococcus xanthus. The researchers suggest that exposure to growth-inhibitory molecules released by M. xanthus leads to the enrichment of resistant isolates.
New scientific method developed at Tel Aviv University: Could revolutionize understanding of the gene PTEN, which is associated with cancer and autism
Researchers at Tel Aviv University have developed a novel method to measure PTEN gene activity, which is associated with cancer and autism. This breakthrough may lead to personalized therapeutics and earlier disease detection.
Researchers identify new p53 targets to combat cancer growth
Researchers have discovered several novel downstream p53 targets that could lead to improved cancer therapies. The study highlights the critical role of p53 in preventing cancer and identifies two new genes, ALDH3A1 and NECTIN4, as potential targets for cancer treatment.
University of Houston researcher awarded $3.2 million to fight childhood cancer at the cellular level
Researchers aim to identify key mechanisms and molecular targets to prevent tumor progression in Rhabdomyosarcoma patients. The study focuses on the TAK1 protein, which plays a significant role in regulating cell growth, and its potential inhibition as a therapeutic approach.
How hungry fat cells could someday starve cancer to death
Researchers at UCSF used CRISPR gene editing technology to transform ordinary white fat cells into 'beige' fat cells that voraciously consume calories to make heat. Implanted near tumors, these cells outcompeted cancer cells for nutrients, beating back five types of cancer in lab experiments.
Microscopy approach offers new way to study cancer therapeutics at single-cell level
Researchers developed a novel microscopy technique to study metabolic changes in individual cancer cells at the single-cell level. They found that radiation treatment caused significant metabolic shifts in head and neck squamous cell carcinoma cells, particularly through the activation of HIF-1α.
Pathogenic variants in retinoblastoma suggest a potential gain-of-function mutation
Researchers found a genetic change, pR552*, that could give the RB1 gene a new function leading to cancer growth. This challenges the common belief that both copies of the RB1 gene must be damaged for cancer to develop.
Nourishing T cells to fight cancer
Researchers at the University of Pittsburgh have developed a new way to grow T cells that can live longer and better destroy cancer cells in mice. By adding a compound called dichloroacetate to growth media, they created T cells less reliant on glucose and more efficient at using other energy sources.
Cell death and aging in cancer research review
A review of cell death and aging in cancer research reveals the significance of cellular senescence in promoting cancer growth. The study highlights the potential of various types of programmed cell death, such as necroptosis and pyroptosis, as therapeutic targets against senescent cells.
Princeton Chemistry develops copper-detection tool to discover possible chelation target for lung cancer
The Chris Chang Lab develops a copper-detection tool to uncover how copper regulates cell growth in lung cancer. The probe identifies cells with elevated copper levels and reveals a connection between copper and the antioxidant response mediated by NRF2.
Emory researchers study the behavior of heart cells in space to find better treatment strategies on earth
Researchers found that heart muscle cells can grow and survive in microgravity, suggesting a new approach to regenerating damaged hearts. The study uses cardiac spheroids to mimic the human heart structure and function, leading to increased survival rates and potential for improved cell therapy.
NUS Medicine study discovers potential for new colorectal cancer treatment
A recent NUS Medicine study found that a molecule called DUSP6 plays a major role in helping colorectal cancer grow, with higher levels linked to poorer prognosis and decreased survival. Researchers suggest blocking DUSP6 could lead to new therapies for CRC treatment.
Genetic tweak optimizes drug-making cells by blocking buildup of toxic byproduct
A new strategy enhances pharmaceutical production in Chinese hamster ovary cells by knocking out a gene circuit responsible for producing lactic acid. The approach improves growth rates and significantly increases protein yield, overcoming a decades-old challenge in biomanufacturing.
Chinese Medical Journal article explores how standardizing organoids can advance living biobanks
Organoids, derived from stem cells, closely mimic human tissue for biomedical research and drug testing. Standardization is crucial for generating reliable results in organoid construction, requiring approved operating procedures and informed consent from donors.
Effects of megakaryocyte conditioned media on endothelial cell angiogenesis
Researchers found that megakaryocyte conditioned media from younger mice was more effective at promoting blood vessel growth and improving healing. The study provides a potential approach for developing new therapies to speed up fracture recovery in older individuals, reducing pain and improving mobility.
Ultrasonication as a tool for directing cell growth and orientation
Researchers develop ultrasound-based method to control cell growth and orientation in cultured muscle cells. The technique uses ultrasonication to promote differentiation of myoblasts into myotubes, offering a promising alternative to current methods.
Study challenges assumptions about how tuberculosis bacteria grow
Researchers at Tufts University discovered that TB bacteria maintain a consistent growth rate throughout their life cycle, defying expectations. The study also reveals new growth behaviors of TB bacteria, including the ability to grow from either end after division.
Revolutionizing biology education: Scientists film ‘giant’ mimivirus in action
Researchers at Tokyo University of Science have successfully captured viral infection process under a light microscope using the giant Mimivirus. The footage showcases the proliferation of the virus and its release from cells, highlighting its biological significance in ecosystems.
University of Cincinnati study sheds light on copper’s role in driving kidney cancer
A new University of Cincinnati Cancer Center study reveals how copper helps clear cell renal cell carcinoma cells grow and advance. Copper accumulation is associated with worse outcomes for patients with ccRCC, and it boosts energy and growth in cancer cells.
The high cost of complexity
A new study led by Arizona State University researcher Michael Lynch explores the substantial energy demands required to maintain and evolve multicellular life. Multicellular organisms require a tenfold increase in energy compared to protists, highlighting how respiration and metabolic processes are crucial for advanced life forms.
Scientists create a world-first 3D cell model to help develop treatments for devastating lip injuries
Researchers successfully immortalized lip cells, enabling the development of clinically relevant lab-based models to test treatments for lip injuries and infections. The 3D cell model was tested with Candida albicans yeast, showing promising results for wound healing and infection studies.
WPI receives federal funding to address anticipated demand for biology and biotechnology professionals and educators
The Graduate Assistance in Areas of National Need program will fund eight doctoral students at WPI, increasing the department's diversity and footprint. The fellowships will help create new career paths in life sciences.
Co-culture system for sustainable cultured meat production
A new co-culture system uses photosynthetic microorganisms to remove waste products and enhance muscle cell growth, resulting in a 30% reduction of lactate and over 90% reduction of ammonia. This innovation provides a low-cost, sustainable alternative to animal serum for cultured meat production.
Researchers use genomic technology to investigate aggressive skin cancer linked to burn scars
Researchers used genomic technology to study Marjolin's ulcer, a rare and highly aggressive skin cancer that grows on chronic burn wounds. The study reveals insights into how keratinocytes switch their function to become cancerous, creating a fertile environment for tumor cells to grow and spread.
New findings on stem cells and development of cancer
Researchers at Umea University have discovered how embryonic stem cells transition into specialized cells, highlighting the importance of LSD1 protein in cancer development. The study suggests that targeting only LSD1's enzymatic activity may not be enough for cancer treatments to be effective.
Claustrophobic cells slow their own growth, forming beautiful patterns of concentric circles
Researchers discovered that dividing bacterial cells adapt to crowded environments by slowing their growth, forming a pattern of concentric circles. This process can inform strategies for controlling the spread of harmful microorganisms, such as in infections or manufacturing.
What turns bacteria into spirals?
A team of researchers discovered a mechanism that determines the spiral shape of Rhodospirillum bacteria, revealing a novel link between cell shape and fitness. The study found that an outer membrane porin-lipoprotein complex modulates elongasome movement to establish cell curvature in R. rubrum.
How a bacterium becomes a permanent resident in a fungus
A team of researchers led by Julia Vorholt at ETH Zurich initiated laboratory partnerships between bacteria and fungi to study the beginnings of an endosymbiotic relationship. They found that when certain bacteria are passed on to the next generation of fungi through spores, the fungus adapts and becomes more inhabited.
A molecular signal works its magic from inside a straitjacket
Researchers at UCSF used cryogenic electron microscopy to study the protein TGF-Beta, which plays a crucial role in development and cancer. They found that TGF-Beta can signal even when bound to a 'straitjacket' within the cell membrane, challenging decades-old dogma on its function.
Evolving the framework of cancer theory
Researchers propose a new approach to understanding cancer evolution, acknowledging the importance of environmental influences and epigenetic changes. By refining the clonal evolution model, they aim to develop more effective cancer therapies that consider the full complexity of cancer cell evolution.
Nature inspires a breakthrough: scientists develop revolutionary egg white-based bioink for advanced tissue engineering
Terasaki Institute scientists have created a novel bioink derived from egg whites, offering abundant proteins and excellent biocompatibility. This breakthrough technology has the potential to create more accurate tissue models for drug testing and develop functional tissue replacements for regenerative medicine applications.
Space-trekking muscle tests drugs for microgravity-induced muscle impairment
A study found that space-traveling muscles have impaired regeneration and gene activities associated with sarcopenia. Drug treatment partially prevented the negative effects of microgravity on muscles, suggesting a potential therapeutic approach for astronauts and older adults.
The geometry of life: Physicists determine what controls biofilm growth
Researchers used interferometry to study biofilm growth and found that the contact angle with the substrate plays a key role in determining fitness. The team discovered that the shape of the biofilm's edge, which resembles a spherical cap, is influenced by this geometry.
Promising role of antidiabetic drug in cancer control
Researchers found that metformin increases levels of microRNAs miR-2110 and miR-132-3p, targeting genes PIK3R3 and STMN1 to slow down cancer cell growth and division. This study provides new insights into metformin's molecular mechanisms and its potential as a preventive agent for reducing cancer growth.
Prostate cancer: Protein identified to reduce tumor growth
Researchers identified protein JUN as a potential therapeutic option to slow tumor growth in prostate cancer, contradicting previous findings that linked high JUN levels to increased tumor growth. The study showed that JUN slows tumor progression and improves immune response, providing a new starting point for therapy development.
Study led by NTU Singapore and Chiba University finds that a common virus can trigger quicker growth of nasopharyngeal cancer
Scientists discover Epstein-Barr virus alters gene regulation in nasopharyngeal cancer cells, leading to rapid tumour growth. The study offers new insights into the link between EBV and NPC, shedding light on intricate processes underlying disease progression.
New mechanisms behind antibiotic resistance
New study reveals two novel mechanisms that contribute to antibiotic resistance in bacteria, accelerating the growth of resistant bacteria during treatment. These mechanisms can occur independently and are linked to increased gene copy number variation and heteroresistance, complicating treatment for patients.
New stem cell research may have implications for liver transplantation
Researchers have successfully grown functional human liver cells in a different species, offering a potential solution to the shortage of donor organs for liver transplants. The breakthrough uses interspecies blastocyst complementation to produce transplantable human liver cells, which can effectively mitigate chronic liver fibrosis.
A link between breast changes and … UTIs?
Researchers found that UTIs can provoke structural changes in breast tissue in mice, which are reversible once the infections are resolved. The study suggests a possible link between UTIs and abnormal breast cell growth, highlighting the importance of considering everyday occurrences on women's well-being.
USC-led study introduces a new and improved way to grow the cells that give rise to the kidney’s filtration system
The study, published in Cell Stem Cell, improves the growth of nephron progenitor cells (NPCs) using a chemical cocktail, enabling sustained growth in a simple 2-dimensional format. The breakthrough has potential for advancing kidney research and discovering new treatments.
NTU Singapore and Temasek Polytechnic scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater
Researchers at NTU Singapore and Temasek Polytechnic develop a new, sustainable feed alternative for farmed Asian seabass, reducing reliance on wild-caught fishmeal. The single cell protein is cultivated from soybean processing wastewater, offering a promising solution to the aquaculture industry's environmental challenges.
NTU Singapore scientists grow ‘mini kidneys,’ revealing new insights into metabolic defects and potential therapy for polycystic kidney disease
Researchers at NTU Singapore successfully grew 'mini kidneys' in the lab, grafted them into live mice, and found a potential treatment for polycystic kidney disease by boosting autophagy. The study suggests that minoxidil could be used to reduce cysts in the novel mouse model.
Cell division quality control ‘stopwatch’ uncovered
Scientists at the University of California San Diego have identified a biochemical pathway that continually surveils mitosis timing and eliminates potentially problematic cells. The 'stopwatch' mechanism uses protein p53 to track cell division time, labeling sequentially delayed divisions as risky.