Researchers at NTU Singapore and Temasek Polytechnic develop a new, sustainable feed alternative for farmed Asian seabass, reducing reliance on wild-caught fishmeal. The single cell protein is cultivated from soybean processing wastewater, offering a promising solution to the aquaculture industry's environmental challenges.
SourceNanyang Technological University·JournalScientific Reports·TypeExperimental study·DateApr 25, 2024
Researchers at NTU Singapore successfully grew 'mini kidneys' in the lab, grafted them into live mice, and found a potential treatment for polycystic kidney disease by boosting autophagy. The study suggests that minoxidil could be used to reduce cysts in the novel mouse model.
SourceNanyang Technological University·JournalCell Stem Cell·TypeExperimental study·DateApr 8, 2024
Scientists at the University of California San Diego have identified a biochemical pathway that continually surveils mitosis timing and eliminates potentially problematic cells. The 'stopwatch' mechanism uses protein p53 to track cell division time, labeling sequentially delayed divisions as risky.
SourceUniversity of California - San Diego·JournalScience·TypeExperimental study·DateMar 28, 2024
Researchers identified a key factor limiting the shapes of fungal hyphae, which are crucial for growth and survival. The study's findings provide insights into the evolution of complex traits and have significant implications for understanding ecological systems and developing new antimicrobials.
SourceNew York University·JournalCell Reports·DateMar 25, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Scientists from UC3M and Johns Hopkins University have developed a computational model that simulates the invasion process of cancer cells based on the characteristics of surrounding tissue and cell junctions. The model allows for predicting tumor evolution in patients by analyzing mechanical properties of the microenvironment.
SourceUniversidad Carlos III de Madrid·JournalActa Biomaterialia·TypeComputational simulation/modeling·DateMar 20, 2024
The study reveals Brat's role in regulating wing imaginal discs regeneration by modulating downstream growth factors. Flies with reduced Brat demonstrated improved wing regeneration but also exhibited deficiencies in cell-fate specification, highlighting the delicate balance required for proper regeneration.
SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalPLOS Genetics·TypeExperimental study·DateMar 19, 2024
A new study has discovered that Streptococcus anginosus bacteria play a significant role in causing stomach cancer. The research showed that S. anginosus infection led to gastric inflammation, cell damage, and the growth of stomach cancer cells, doubling tumour size and weight in some cases.
SourceNanyang Technological University·JournalCell·TypeExperimental study·DateMar 17, 2024
Research by Johns Hopkins Medicine suggests that increased stiffness in aging skin contributes to higher rates of melanoma metastasis by stimulating blood vessel growth and making them leaky. Treating older mice with drugs blocking ICAM1 prevented these changes, shrinking tumors and reducing metastasis.
SourceJohns Hopkins Medicine·JournalNature Aging·DateMar 12, 2024
Researchers at Washington State University discovered a way to trick bacteria into sending death signals to stop the growth of their slimy biofilms, which can lead to deadly infections. The study found that these 'death extracellular vesicles' can reduce bacterial growth by up to 99.99% in laboratory experiments.
SourceWashington State University·JournalBiofilm·DateMar 5, 2024
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A new study has identified a strategy used by early-stage cancer cells to evade the immune system. By turning on the gene SOX17, these cells create an immunosuppressive environment that prevents them from being detected. This gene helps cancer cells ignore immune messages and grow in the presence of an immune system.
SourceMassachusetts Institute of Technology·JournalNature·DateFeb 28, 2024
Researchers discovered genes encoding growth regulators normally not present in myeloid cells are expressed by leukaemic stem cells, allowing them to grow. Repurposed drugs targeting these receptors show promise in blocking stem cell growth and preventing disease relapse in specific types of AML.
SourceUniversity of Birmingham·JournalNature Communications·TypeExperimental study·DateFeb 15, 2024
Researchers found that USP1 inhibits cdc42, increases EWS-FLI1 transcriptional output, and simulates Ewing sarcoma growth. A pharmacological inhibitor of USP1 activated cdc42 and inhibited Ewing sarcoma growth.
SourceImpact Journals LLC·JournalGenes & Cancer·DateFeb 14, 2024
Researchers at TU Wien create artificial cartilage tissue by colonizing porous plastic spheres with cells, achieving seamless integration and uniform structure. The novel technique has potential for medical applications, including replacing injured cartilage.
SourceVienna University of Technology·JournalActa Biomaterialia·DateFeb 12, 2024
Researchers at Imperial College London created a novel molecular toolkit to enhance compound production in yeast communities. The toolkit allowed them to split the resveratrol production pathway, resulting in enhanced production and more stable partnerships between yeast strains.
SourceImperial College London·JournalNature Microbiology·DateFeb 7, 2024
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers at Duke-NUS Medical School discovered a novel enzyme, FAXDC2, that plays a pivotal role in cholesterol synthesis and cancer progression. The study highlights the potential vulnerability of cancer cells to targeted therapeutic intervention. Further research is needed to explore the therapeutic potential of targeting FAXDC2 i...
SourceDuke-NUS Medical School·JournalJournal of Clinical Investigation·TypeExperimental study·DateFeb 2, 2024
A team of researchers found that diffuse anaplasia (DA) subtype of Wilms tumor grows despite high DNA damage and TP53 mutation, leading to resistance to chemotherapy. The study suggests that DA histology emerges through accumulating DNA damage and CNAs, creating selection pressure for TP53 mutations.
SourceNagoya University·JournalModern Pathology·DateFeb 1, 2024
Researchers have successfully grown striated muscle layers and flat fat layers using glutenin, a non-allergenic wheat protein. The edible film-based scaffolds can be combined to produce meat-like textures, promising a more realistic cultivated meat product.
SourceAmerican Chemical Society·JournalACS Biomaterials Science & Engineering·DateJan 29, 2024
Researchers have engineered bovine muscle stem cells to produce their own fibroblast growth factor, reducing the cost of production for cultivated meat. This innovation could lead to more affordable and accessible cultured meat products in the near future.
SourceTufts University·JournalCell Reports Sustainability·TypeExperimental study·DateJan 26, 2024
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers at Duke University successfully introduced a mutated BRAF gene into rat heart tissue, inducing growth and cell division. However, the approach was associated with significant loss of contractile strength, highlighting the need for precise control over gene activation and delivery.
SourceDuke University·JournalScience Advances·TypeExperimental study·DateJan 24, 2024
Researchers develop nanofibrous matrices containing MXene nanoparticles to aid in muscle regeneration. The study reveals molecular mechanisms behind the effects of MXene nanoparticles on muscle growth, suggesting a promising avenue for treating volumetric muscle loss and muscle-related ailments.
SourcePusan National University·JournalNano-Micro Letters·TypeExperimental study·DateJan 24, 2024
A new study published in Oncogene highlights the effectiveness of MDX-124, a therapeutic drug targeting annexin-A1, which promotes tumour progression. High annexin-A1 expression levels correlate with poorer overall survival in various cancers.
SourceAnglia Ruskin University·JournalOncogene·TypeRandomized controlled/clinical trial·DateJan 19, 2024
Researchers at UC Riverside have identified a crucial protein that controls plant responses to stress and aging. The discovery reveals the importance of Golgi bodies in maintaining cellular health and highlights their potential role in human aging.
SourceUniversity of California - Riverside·JournalNature Plants·DateJan 17, 2024
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A study by the University of Sheffield found that breast cancer cells take advantage of nutrients in the extracellular matrix when faced with nutrient starvation. The cells use an ingestion process called macropinocytosis to consume the matrix, breaking it down into energy-releasing substrates.
SourceUniversity of Sheffield·JournalPLOS Biology·TypeExperimental study·DateJan 16, 2024
Breast cancer cells survive by consuming the extracellular matrix when nutrients are scarce. The process involves macropinocytosis and metabolic conversion of key amino acids to energy-releasing substrates. This mechanism could represent a novel therapeutic target.
SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateJan 16, 2024
Cancer stem cell-derived exosomes (CSC-Exos) are essential for communication between CSCs and other cells in the tumor microenvironment, contributing to cancer progression. The editorial highlights their potential as a novel clinical tool for diagnosis, prognosis, prevention of tumor recurrence, and therapeutic strategy
SourceImpact Journals LLC·JournalOncotarget·TypeCommentary/editorial·DateJan 3, 2024
Cysteine is sensed by a protein called Pib2 and binds with it to activate TORC1, promoting cell proliferation. The study found that all 20 amino acids differently affect TORC1 using two pathways: Pib2 and Gtr.
SourceOsaka University·JournalCell Reports·TypeExperimental study·DateDec 21, 2023
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers explore the properties of cytostatic persisters in cancer treatment, highlighting their therapeutic potential and challenges. The study suggests that targeting these persisters before resistance emerges can reduce cancer recurrence.
SourceImpact Journals LLC·JournalOncotarget·TypeCommentary/editorial·DateDec 13, 2023
Researchers have identified the genetic defect causing infantile cystinosis, a rare disease that shortens lifespan, and developed a protocol to differentiate stem cells into healthy kidney cells. The study suggests using CRISPR genome editing to repair the defective gene and potentially cure the disease.
SourceUniversity at Buffalo·JournalInternational Journal of Molecular Sciences·DateDec 11, 2023
A recent study by Goethe University Frankfurt has identified a mechanism that could be a suitable starting point for developing novel drugs against leukemia cells. The researchers discovered that the mutated NPM1 gene variant drives pro-autophagic activity, enabling cancer cells to recycle their structures and meet their needs.
SourceGoethe University Frankfurt·JournalCell Reports·TypeExperimental study·DateDec 4, 2023
Scientists have developed a drug-eluting hydrogel that provides sustained, pH-dependent drug co-delivery and promotes anti-tumor immune responses, reducing tumor cell proliferation and growth. The treatment shows promise in treating hepatocellular carcinoma, with enhanced efficacy compared to traditional methods.
SourceTerasaki Institute for Biomedical Innovation·JournalAdvanced Functional Materials·TypeExperimental study·DateNov 29, 2023
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Extracellular vesicles have been found to transport bacterial products into human cells, alerting the immune system and potentially affecting physiology. This discovery explains a key mechanism by which bacteria impact our health, with implications for both infections and normal bodily functions.
SourceUniversity of Connecticut·JournalNature Cell Biology·TypeExperimental study·DateNov 27, 2023
A new AI tool combines cancerous and non-cancerous cell patterns to predict breast cancer outcomes, allowing for more precise treatment plans. This could lead to reduced chemotherapy duration and intensity for some patients.
SourceNorthwestern University·JournalNature Medicine·DateNov 27, 2023
Cancer cells' uncontrolled growth leads to a loss of ability to divide due to genetic damage accumulation. Simultaneous treatment with growth and division inhibitors can restore cellular function.
SourceETH Zurich·JournalMolecular Cell·TypeExperimental study·DateNov 17, 2023
Researchers found that cultivating Euglena in tomato juice resulted in high cell densities and tightly packed chloroplasts, outperforming other beverages. The nutrient composition of tomato juice is suitable for Euglena growth, offering a promising solution to the shortage of animal protein and potential health benefits.
SourceTokyo University of Science·JournalSustainable Food Technology·TypeExperimental study·DateNov 16, 2023
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers at Texas A&M University have found a correlation between flavonoid compounds and reduced endometriosis symptoms. Flavonoids like Quercetin and Kaempferol show promise in easing inflammation, with studies suggesting they may help suppress the symptoms of inflammatory diseases like endometriosis.
SourceTexas A&M University·JournalEndocrinology·DateNov 7, 2023
Researchers identified a mechanism that fuels cancer cell growth and developed a new strategy to restrict this process. By restricting glucose in lung cancer cells, they found it caused the cells to lose their specialized features, making them more aggressive.
SourceUniversity of California - Los Angeles Health Sciences·JournalCancer Research·DateNov 7, 2023
A recent study published in the Journal of Cell Biology has made significant progress in understanding autophagy and lipid recycling. Researchers used yeast as a model organism to identify key players in the process, including Atg15, Pep4, and Prb1, and demonstrated that Pep4 and Prb1 activate Atg15 to break down phospholipid bilayers.
SourceTokyo Institute of Technology·JournalJournal of Cell Biology·TypeExperimental study·DateNov 2, 2023
A new tool has been developed to rapidly grow cancer-killing white blood cells, called T cells, which could advance the availability of immunotherapy. The bioreactor is 30% faster than current technologies and can be self-contained in a sterile cabinet.
SourceWashington State University·JournalBiotechnology Progress·DateOct 26, 2023
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Mammalian cells consume bacteriophages, killing bacteria and promoting cellular growth and survival. The study suggests that phage particles serve as a nutritionally enriched resource, triggering signaling pathway events that enhance cellular health.
SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateOct 26, 2023
A team of researchers found that fibroblast cells cultured on substrates with varying degrees of stiffness exhibit changes in cell structure, function, and TGF-β activity, which regulates ECM architecture. This study provides insights into how mechanical forces influence wound healing and tissue development.
SourceIndian Institute of Science (IISc)·JournalBioengineering·DateOct 25, 2023
Researchers created a hydrogel mat with magnetic microparticles that mimic the forces of exercise. The team found that regularly exercising muscle cells resulted in longer, aligned fibers, and improved contraction capabilities.
SourceMassachusetts Institute of Technology·JournalDevice·DateOct 20, 2023
Researchers discovered a new role for extracellular signal-regulated kinase (ERK) in a pathway activated by interferon-gamma that leads to cancer cell death. Hyperactivation of ERK causes stress in cells, triggering cell death through specific proteins DR5 and NOXA.
SourceUniversity of California - Los Angeles Health Sciences·JournalMolecular Cancer·DateOct 9, 2023
A University of Basel study reveals that high levels of arginine drive metabolic reprogramming to promote tumor growth. The findings suggest targeting the specific arginine-binding factor for effective liver cancer treatment.
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers at Mayo Clinic discovered that senescent macrophages in the lung promote tumor growth by blocking the immune system's response to abnormal cell growth. Eliminating these senescent cells delays tumor formation, suggesting a potential therapeutic target for cancer treatment.
A team of researchers at Utah State University has successfully created an in vitro model of Bruch's membrane, a layer in the retina that deteriorates with age. The model uses hagfish slime proteins to replicate the natural aging process and disease progression, providing a valuable tool for studying age-related macular degeneration.
SourceUtah State University·JournalACS Biomaterials Science & Engineering·TypeExperimental study·DateSep 13, 2023
Researchers identified how prostate cancer cells achieve cell growth free from usual growth cues and regulators. A protein called PLEKHS1 was found to be a major driver of PI3K activation and cancer growth progression in mouse models.
SourceBabraham Institute·JournalMolecular Cell·TypeExperimental study·DateSep 11, 2023
Researchers found that enteroendocrine cells in Drosophila intestinal epithelium undergo dedifferentiation into intestinal stem cells in response to nutritional changes, such as recovery from starvation. This process is vital for ISC expansion and subsequent intestinal growth following food intake.
SourceTohoku University·JournalDevelopmental Cell·DateSep 11, 2023
A team of Chinese and UK researchers has identified superoxide dismutase 1 (SOD1) as a potential target for reversing drug resistance in ovarian cancer. By using nanoparticles to deliver siRNA that reduces SOD1 levels, the study showed reduced growth and decreased resistance to cisplatin in female mice.
SourceXi'an Jiaotong-Liverpool University·JournalCancer Gene Therapy·TypeExperimental study·DateSep 6, 2023
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Scientists at the Terasaki Institute for Biomedical Innovation have developed a new bioink that enhances the formation of mature skeletal muscle tissue from muscle precursor cells, increasing efficiency and potential therapies for muscle loss or injury. The bioink's sustained delivery of IGF-1 promotes muscle regeneration and repair.
SourceTerasaki Institute for Biomedical Innovation·JournalMacromolecular Bioscience·TypeExperimental study·DateAug 29, 2023
Glutamine metabolism plays a crucial role in cancer cell growth and survival, with its inhibition shown to block cancer cell growth in vivo and in vitro. A recent editorial paper suggests that glutamine dysregulation may also impact the tumor microenvironment, potentially leading to increased oxidative stress and cancer cell death.
SourceImpact Journals LLC·JournalOncotarget·TypeCommentary/editorial·DateAug 16, 2023
Researchers found that Epstein-Barr virus induces B cell growth transformation through the activation of the cancer-related gene IMPDH2, leading to uncontrolled proliferation. The study used primary B cells and found that inhibiting IMPDH2 can suppress post-transplant lymphoproliferative disorder (PTLD) development.
SourceFujita Health University·JournalMicrobiology Spectrum·TypeExperimental study·DateAug 7, 2023
Researchers found that confined epithelial cells regulate their size and cell cycle separately, suppressing growth but not division length. The team used lab-grown tissue to observe how cells respond to confinement, revealing a new framework for understanding tissue development and growth.
SourceUniversity of Chicago·JournalDevelopmental Cell·DateJul 28, 2023
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers found that epigallocatechin gallate (EGCG) reduces protein levels of fibronectin by 46-52% and disrupts pathways involved in fibroid tumor cell growth. EGCG supplements may provide an easily accessible and natural way to relieve symptoms and slow fibroid growth.
SourceJohns Hopkins Medicine·JournalScientific Reports·DateJul 12, 2023
Plant roots detect temperature changes and adjust their growth accordingly. Researchers found that root cells produce more auxin in response to elevated temperatures, stimulating cell division and allowing roots to grow deeper into the soil. This discovery could help develop new approaches for plant breeding against climate change.
SourceMartin-Luther-Universität Halle-Wittenberg·JournalThe EMBO Journal·TypeExperimental study·DateJul 10, 2023
Scientists have discovered a new class of compounds called cyanotriazoles that effectively inhibit the growth of trypanosomes, the parasites responsible for Chagas disease and African sleeping sickness. The results offer hope for the development of new and improved treatments for these neglected tropical diseases.
SourceSwiss Tropical and Public Health Institute·JournalScience·DateJun 29, 2023
A team at Osaka University identified a crucial protein facilitating proper chromosome movement when cells divide. The research revealed that the Cupin domain of CENP-C is essential for its function, supporting centromere/kinetochore assembly and maintaining genomic integrity.
SourceOsaka University·JournalMolecular Cell·TypeExperimental study·DateJun 8, 2023
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Cancer cells in brain tumors produce lipids at higher rates than surrounding healthy tissue, offering clues for treatment strategies. The study provides insights into the unique biochemical processes fueling cancer growth in the brain.
SourceWashington University in St. Louis·JournalNature Communications·TypeExperimental study·DateJun 1, 2023
Researchers discovered that ZC3H11A is essential for regulating metabolic genes in embryos and their absence leads to complete lethality. The study's findings suggest that ZC3 may be a promising therapeutic target for the development of anti-viral agents against medically significant human viruses.
SourceUppsala University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 31, 2023
Researchers found that formalin fixation does not significantly alter the polarimetric properties of brain tissue, making it suitable for training machine-learning models. The study suggests that formalin-fixed brain tissue specimens can provide high-quality data for rapid and accurate diagnostic imaging in surgery.
SourceSPIE--International Society for Optics and Photonics·JournalNeurophotonics·DateMay 25, 2023
Researchers at UC San Diego and Stanford University have developed a roadmap of root chemicals that are critical to plant growth, providing new insights into plant development. The study reveals that key small molecules are clustered in patches across the root, suggesting a purposeful distribution for optimal growth.
SourceUniversity of California - San Diego·JournalNature Communications·TypeExperimental study·DateMay 25, 2023
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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.