Articles tagged with Cytoplasm
Researchers found that Vax2 protein shuttles between nucleus and cytoplasm in response to Sonic hedgehog signaling molecule. In its nuclear state, Vax2 represses Pax6, allowing optic nerve development. In contrast, Pax6 regulates retinal fate. This coordination is crucial for proper eye development.
Scientists at Cold Spring Harbor Laboratory identified a messenger RNA molecule that switches from non-protein coding status to protein coding status in response to cellular stress. This 'cut and run' mechanism likely controls the expression of many genes, providing a rapid response to viral infection or other stresses.
Researchers found that the number of vertebrae in cloned carp-goldfish fish was determined by the goldfish's egg cytoplasm, not its genetic code. The study suggests a
A recent study by Sergei Sokol and colleagues reveals that the Wnt signalling protein Dishevelled (Dsh) has a critical role in the nucleus to respond to certain Wnt signals. In contrast, nuclear localisation is not required for its function in non-canonical signaling pathways.
A new study found that the secretory path's activity is closely tied to the nucleus' structure and functions, with disruptions impacting gene expression and cellular growth. This research may hold key to developing molecular therapies for these genetic diseases.
Researchers found that calcium influx into mitochondria triggers neuron death, while changes in cytoplasmic calcium have a more subtle effect on cell health. The study suggests designing drugs to target mitochondria could prevent or intervene in glutamate-induced neuronal damage.