Reify's Visible Discovery technology demonstrates high-throughput in vivo and in vitro phenotypic screens for cardiovascular structure and function, as well as subcellular particle movement. The platform provides fast, unbiased results with minimal end-user intervention.
Researchers at JILA use laser pulses to take snapshots of atom collisions, revealing how atoms briefly lose form and energy when colliding. The results provide new insights into atomic dynamics and the laws of physics.
Researchers found a possible genetic link between cystic fibrosis gene mutations and young-onset pancreatic cancer. The study showed that individuals carrying the CFTR gene mutation are at increased risk for pancreatitis, which may also increase the risk of developing pancreatic cancer.
A study of Norwegian medical students found that nearly 70% self-prescribed medication in their first year after graduation, a trend that continued into their fourth and ninth years. The most commonly self-prescribed medications were antibiotics, contraceptives, and analgesics.
A recent study published in Science demonstrates a new and sensitive assay for infecting prion diseases, including CJD and scrapie. The research shows that persistent replication of the infectious agent provides protection against more virulent strains, without requiring misfolded prions.
A new study reveals that selective logging in the Amazon Basin causes widespread destruction, losing an area roughly twice the size of Connecticut annually. This practice, which removes one or two trees and leaves the rest intact, contributes to climate change by releasing more carbon dioxide into the atmosphere than previously assumed.
Researchers identified a human milk component that blocks HIV interaction with dendritic cells and inhibits viral transfer to CD4+ T-lymphocytes. This discovery has significant implications for developing agents to block HIV transmission.
Researchers pinpoint CD36 as the first candidate for detecting fatty acids in the oral cavity, influencing digestive physiology and potentially increasing obesity risk. The study also reveals an alteration in the fat perception system may impact HIV transmission through human milk.
Computer simulations reveal that heat conduction is surprisingly high between liquid interfaces, challenging conventional wisdom on thermal conductivity. This finding has significant implications for fields like cancer treatment and computer chip manufacturing.
A study by the University of Iowa found that 37% of high schools have defibrillators, but surprisingly, cardiac arrests are relatively uncommon in these schools, with a rate of about 2 percent per year. In contrast, senior centers had higher rates of cardiac arrests, with only 10% having defibrillators.
A new study found that drug-eluting stents like CYPHER are cheaper than open-heart surgery, saving patients and the healthcare system $6,487 on average over a year. The research also shows improved patient outcomes with stent treatment.
The HERA study found that Herceptin reduces the risk of cancer coming back by 52% and death by 33% in early-stage HER2-positive breast cancer. The results provide new hope for women with this aggressive form of breast cancer, offering improved survival rates.
Dr. Henry Gabelnick, a renowned expert in reproductive health and microbicide development, has been awarded the lifetime achievement award by International Conference on AIDS India. The award recognizes his significant contributions to the field, including the development of Ushercell, a microbicide consisting of cellulose sulfate.
A study published in the Journal of Clinical Investigation found that P-glycoprotein plays a critical role in transporting amyloid-beta (Abeta) from the brain to the blood via the blood-brain barrier. The research suggests that altering P-glycoprotein function due to chronic drug treatment could increase Abeta deposition and risk of de...
Scientists at Cold Spring Harbor Laboratory identified a messenger RNA molecule that switches from non-protein coding status to protein coding status in response to cellular stress. This 'cut and run' mechanism likely controls the expression of many genes, providing a rapid response to viral infection or other stresses.
Rice University scientists have constructed the world's smallest car, a single molecule 'nanocar' with four buckyball wheels. The nanocar can roll on its axles in a direction perpendicular to its movement, marking a significant achievement in bottom-up molecular manufacturing.
Researchers found menin promotes acute leukemia by working with mutated MLL proteins, leading to the formation of cancer cells. Removing menin stops cell proliferation and allows cells to mature into healthy blood cells.
Researchers warn that the breakdown of major ice sheets in Greenland and Antarctica could significantly speed up sea level rise, potentially doubling current projections. The study suggests that these mechanisms should be carefully considered in future climate models to ensure accurate sea level rise predictions.
The International Council for Science urges its members to reaffirm commitment to the 'Universality of Science' due to growing restrictions on scientific freedoms. The principle emphasizes freedom of movement, association, expression, and access to data and research materials.
A combination of factors makes future landslides inevitable in La Conchita, including active faulting, rapid tectonic uplift, and weak rocks. Experts propose a beach park solution and installation of sensors to detect slope movement to mitigate the risk of landslides.
Researchers have developed a prototype device using trained Microplitis croceipes wasps to detect target odors, including explosives and toxic fungi. The device, called Wasp Hound, can be used for various applications, such as detecting plant diseases, chemical odors associated with human diseases, and hidden bodies.
A new report from ICSU recommends establishing an international scientific data forum to promote coordinated data collection and distribution. The report identifies key challenges, including inadequate legal frameworks, preservation, and archiving of data, which exacerbate inequities between scientists in rich and poor nations.
Researchers found that children with bipolar disorder exhibit over-reactive amygdala responses to negative stimuli, leading to under-reactive cognitive behavior. This study highlights the need for targeted treatments and interventions for pediatric bipolar disorder.
Research reveals that many poor children in low-income countries are missing out on effective child survival strategies, including vitamin A supplements, safe water, and immunizations. Countries with higher coverage rates have less inequity than those with lower coverage rates.
Researchers at Vanderbilt University have discovered a way to make quantum dots produce broad-spectrum white light, similar to sunlight. The discovery uses 'magic-sized' nanocrystals that emit light without chemical treatment, offering a potential sustainable alternative to traditional lighting.
Researchers at The Wistar Institute have identified a novel multi-protein complex called the Integrator that plays a central role in processing small nuclear RNAs. This complex, which consists of at least 12 subunits, appears to bind to both CTD and specific genes coding for snRNAs.
Proteome Systems has received a $20 million grant from the US government to develop therapeutic compounds for treating radiation damage. The company's 'catalytic scavenger compounds' show potential in preventing radiation-induced tissue damage and are expected to protect victims of radiation exposure, including first responders.
Researchers found that early vaccination with pneumococcus and T-cell vaccine can rebuild immunity in cancer patients after chemotherapy, with protection developing within a month. This study paves the way for personalized therapy using engineered T-cells to boost the immune system against tumors.
FSU researcher Ben Wang is pushing the boundaries of buckypaper, a material made from carbon nanotubes that's twice as hard as a diamond. The potential applications are vast, including developing stronger aerospace structures, more-effective body armor and next-generation computer displays.
Researchers found high HCV rates among former plasma/blood donors and villagers who received blood transfusions. Unhygienic plasma donation and blood transfusion are strong risk factors for HCV infection in rural central China.
Recent studies have shown that combining standard chemotherapy with new monoclonal antibody therapies can significantly improve survival rates for patients with follicular lymphoma. The latest study, led by Richard I. Fisher, found a 91% four-year survival rate for patients treated with this regimen.
A study by Case Western Reserve University researchers found that apigenin, a plant flavonoid, slowed tumor growth in mice with prostate cancer. Apigenin also reduced IGF-1 levels associated with increased cancer risk and triggered cell self-destruction.
A new satellite imaging method detects selective logging in the Brazilian Amazon, revealing twice the extent of forest degradation as previously estimated. Logging causes major ecological disruptions, including increased carbon flow to the atmosphere and area damage.
Researchers at Berkeley Lab have developed dual nanocrystal solar cells that are as cheap and easy to make as organic polymer-based solar cells. The new devices, comprising cadmium-selenide and cadmium-telluride, offer improved stability in air due to the absence of organic materials.
Researchers at NIST have successfully assembled and disassembled long chains of magnetic nanoparticles, offering potential applications in medical imaging and information storage. The chains are formed using a weak magnetic field, which induces alignment of the nanoparticles and allows for controlled manipulation.
A meta-analysis of seven head-to-head drug-eluting stent trials found that the CYPHER Stent reduces the need for re-treatment by about 30% compared to Taxus Stent-treated patients, regardless of patient and lesion types. The CYPHER Stent's strong clinical performance is established through rigorous analysis.
A recent study using high-resolution satellite data found that selective logging in the Brazilian Amazon has been underestimated by half, with an annual extent of around 4,685 to 7,973 square miles. This has significant ecological implications for the region and beyond, including increased carbon emissions and biodiversity loss.
Scientists found that P-glycoprotein accelerates clearance of amyloid beta from the brain, potentially reducing Alzheimer's risk. The study suggests that pharmaceuticals affecting Pgp activity levels may also influence Alzheimer's risk.
The Bush Administration proposed purchasing 25% of its food aid abroad to reduce transportation costs, but Senate leaders opposed the move, prioritizing domestic interests over international efforts to combat hunger. The World Food Programme emphasized the need for a concerted global response to address the issue.
Yale researchers have developed a method to count absolute numbers of individual protein molecules inside living cells and measure their locations with high accuracy. This breakthrough addresses fundamental hurdles for studying biology quantitatively, enabling the measurement of protein concentrations in various cellular structures.
Researchers have discovered functional ion channels in human stem cells that regulate cell differentiation and proliferation. By targeting specific potassium channels, scientists may be able to control cell growth and prevent tumor formation, potentially leading to new treatments for various diseases.
A study analyzed 802 Sri Lankan patients who ingested three common organophosphorus insecticides, highlighting substantial variation in clinical course and response to treatment. Current treatment is only partly effective, with case fatality rates often exceeding 10%.