Articles tagged with Effector T Cells
The Lag-3 gene controls regulatory T-cell function, which can prevent autoimmune diseases but also inhibit anti-cancer immune attacks. Researchers found that manipulating Lag-3 levels on T cells might prevent autoimmune diseases or amplify immune system attacks on cancer cells.
Researchers studied insulitis lesions in genetically engineered mice and discovered that inducible co-stimulator (ICOS) plays a crucial role in keeping insulitis respectful. Blocking ICOS disrupts the balance between T effector and regulatory cells, leading to diabetes progression.
Researchers found a marker for long-term immunity in CD8 T cells using the interleukin 7 (IL-7) receptor. This discovery can help scientists create more effective vaccines and develop new treatments for chronic viral infections and cancer.