Articles tagged with Stem Cell Self Renewal
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The study found that aging stem cells in fruit flies experienced a decline in growth factor unpaired (upd), leading to reduced stem cell numbers. Artificially increasing upd levels delayed the loss of germline stem cells, suggesting that the niche's molecular signals govern stem cell behavior.
The Xie Lab has demonstrated that the microRNA pathway is essential for controlling self-renewal of germline and somatic stem cells in Drosophila ovaries. Understanding this mechanism could lead to developing new methods for expanding stem cell populations for tissue repair.
Researchers at U of MN identified 14 genes that regulate blood stem cell development, which could lead to new treatments for blood disorders and cancers. The discovery provides insight into understanding how to stimulate blood stem cells to multiply in the laboratory.
A team of researchers led by Gary Gilliland discovered that certain leukemia oncogenes can reactivate self-renewal programs in mature white blood cells. This finding has significant implications for understanding and treating chronic myeloid leukemia, a disease fueled by a small population of cancer stem cells.
Scientists discover that the Math1 gene triggers the differentiation of three types of intestinal cells from stem cells, including goblet, enteroendocrine, and Paneth cells. This finding provides significant insights into the regulatory control of intestinal stem cells and their role in disease treatment.
Researchers at Duke University Medical Center have identified a cell component called the spectrosome that guides reproductive cells to self-renew and mature differentiated cells in fruit flies. The finding may help explain how men continuously produce sperm and why some stem cells lose control, forming cancerous tumors.