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Clock gene may connect mood and sleep

Researchers discovered a molecular link between mood disorders and circadian rhythms in a study on familial advanced sleep phase (FASP) and faulty PER3 gene variants. Mice carrying the faulty gene exhibited depression-like symptoms when exposed to short light periods, mirroring human seasonal affective disorder.

Unraveling the gene-environment interaction

Research in Child Development Journal explores gene-environment interaction and epigenetics' role in shaping child behavior. Studies link methylation of specific genes to important developmental outcomes from prenatal period through young adulthood.

A new method furthers understanding of evolutionary genetics

Researchers developed a new method to study genetic differences between long-separated species of yeast, providing insights into how mutations shape growth and behavior. The discovery has implications for understanding age-related diseases and developing new treatments.

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Parasitic ants alter how captive ants recognize nest mates

Researchers found that enslaved Formica ant colonies were more genetically and chemically diverse than their free-living counterparts. This diversity is likely caused by seasonal raids to steal pupae from adjacent host colonies, leading to changes in how the ants recognize nest mates.

Disruptions to embryonic reprogramming alter adult mouse behavior

Researchers found that defective epigenetic reprogramming in embryos can lead to abnormal repetitive behaviors and changes in brain wiring in adulthood. Studies using genetically engineered mice showed that the enzyme KDM1A plays a crucial role in regulating gene expression during development.

Estrogens alleviate hyperactivity in zebrafish with autism gene

Researchers found that estrogens selectively calm hyperactive behavior in zebrafish with a genetic mutation linked to autism. The study suggests estrogens may target specific brain pathways affected in ASD, which could lead to new treatments for the condition.

Disclosure of incidental genetic findings can have positive impact for patients

A randomized controlled study published in Annals of Internal Medicine found that providing information about coronary artery disease risk to patients undergoing genetic testing for Alzheimer's disease improved health behaviors and reduced distress. The study suggests that the disclosure of secondary findings from genomic testing can h...

Antisocial behavior: Understanding the influence of genes and the environment

A longitudinal study found that exposure to violence in childhood is linked to increased symptoms of conduct disorder and antisocial personality in adolescence and adulthood. The MAOA gene was also identified as a key moderator of this relationship, with certain variants increasing the risk of aggressive behavior and partner violence.

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Conflict among honey bee genes supports theory of altruism

Research supports theory of kin selection, suggesting that altruistic behavior occurs to pass genes to next generation. Genes inherited from queen promote altruistic behavior in worker bees, while those from father's promote selfish behavior.

Small changes in DNA can affect nicotine consumption

Researchers found that genetic variants in the beta-3 subunit of nicotinic acetylcholine receptors can alter nicotine behavior. People carrying the more common version are more likely to have problems with nicotine use.

Fearful chickens and worried mice: Shared genetic influences on anxiety

A new study identifies genetic influences on anxiety in chickens that may also apply to mice and humans. The research found that genes linked to anxiety in chickens were associated with similar behaviors in mice, while some were connected to schizophrenia or bipolar disorder in large human studies.

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Weight-loss programs tailored to a person's genome may be coming soon

A recent report finds that genetic information and data collection from noninvasive devices can help develop personalized weight management plans. With the falling cost of genome sequencing and portable monitors, scientists have the ability to collect the necessary data but need better analytical tools to analyze it.

Gene controls stress hormone production in macaques

Researchers found that a specific COMT gene variant is associated with higher cortisol levels in stressed Japanese macaques, leading to more aggressive behavior. This study provides insight into the genetic basis of stress hormone production in non-human primates and its potential connections to human behavior.

Understanding body language of mice

Harvard Medical School scientists developed a computational technique to analyze mouse movements, organizing them into distinct pose sequences with their own syllables and grammar. This breakthrough solves the problem of objectively studying complex animal behavior without human observers.

Researchers identify gene possibly linked with methamphetamine addiction

Researchers at Boston University School of Medicine have identified a gene, Hnrnph1, that is casually associated with the behavioral response to methamphetamine. This finding may have implications for understanding the genetic basis of methamphetamine addiction and developing novel therapeutics.

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Some prairie vole brains are better wired for sexual fidelity

Researchers at the University of Texas at Austin found that natural selection drives prairie voles to be either fully monogamous or seek multiple partners due to genetic brain differences. The findings suggest that these genetic variations are not favored by natural selection, but rather co-exist in the population.

Sins of the father could weigh on the next generation: RMIT study

A recent RMIT University study found that a father's diet before conception can affect the mental health of their unborn children. The research discovered that genetic changes caused by the father's diet were passed on to the next generation, leading to differences in anxiety levels and behavior.

Can a bonobo keep the beat?

A female bonobo named Kuni was found to have a spontaneous drumming tempo of 270 beats per minute, faster than observed in human children. She synchronized her drumming with the human drummer on 54% of trials, with greater success near her preferred tempo.

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New method for imaging marmoset brains

Researchers developed a new system to image individual neurons in the marmoset brain, overcoming limitations with two-photon microscopy. This allows for long-term study of neural activity related to cognitive and social behaviors.

A 'supergene' underlies genetic differences sexual behaviour in male ruff

Researchers have discovered a 'supergene' underlying genetic differences in sexual behaviour among male ruffs, with Satellite and Faeder males carrying a chromosomal inversion that has been maintained for about 4 million years. The study found an association between the 'supergene', testosterone levels, and altered behaviour.

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Study spells out why some insects kill their mothers

Researchers found that worker wasps in colonies with more full siblings are more likely to kill their queens, allowing them to lay male eggs and outcompete the queen for reproduction. This behavior is driven by kin selection theory, which predicts that workers favor close relatives over distant ones.

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Females more promiscuous in colder climates, says insect study

A study by the University of Exeter found that female insects are more likely to have multiple partners in colder climates and prefer monogamy in hotter conditions. The research suggests that an individual's genes play a significant role in determining their mating behavior.

New study: What you didn't know about naked mole-rats

A recent University of Virginia-led study found that naked mole-rats are not genetically isolated and are actually part of larger wild populations with diverse genetics. This challenges the long-held assumption about their social behavior and mating habits.

Genetic defense for violent crimes could backfire for defendants

New research suggests that jurors may support an insanity defense if they believe a defendant has a genetic explanation for their actions, but also view them as a persistent threat. The study found that participants were more likely to support a diminished capacity defense and believed the defendant had less control over their actions.

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Beetles provide clues about the genetic foundations of parenthood

Researchers discovered that burying beetles express specific genes controlling parenting behaviors when single-parented, but not when appearing to co-parent. This finding provides insights into the fundamental genetics of parenthood in insects and may inform studies on social dynamics in other animals.

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Why do so many children born with heart defects have trouble in school?

Researchers at the University of Utah are exploring the link between congenital heart defects and neurological disorders in children, discovering genetic mutations that affect both heart and brain function. The goal is to develop precision medicine for CHD patients and tailor treatment based on genomic sequence.

Genetic tug of war in the brain influences behavior

Researchers discovered noncanonical genomic imprinting in mice brains, affecting serotonin and dopamine production. The study highlights a targeted form of genetic control that can influence offspring behavior and may contribute to brain disorders like autism.

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Research finds ovarian hormones play genes like a fiddle

A recent study by Kelly Klump at Michigan State University reveals that ovarian hormones influence eating disorders in women by turning genetic risk on and off. Changes in hormone levels drive increases in binge eating and emotional eating across the menstrual cycle.

Brain imaging shows how children inherit their parents' anxiety

A new study published in PNAS found that anxious parents are more likely to have anxious offspring, and that an over-active brain circuit may set the stage for developing anxiety and depressive disorders. The research identified three brain regions responsible for passing anxiety from generation to generation.

ASHG honors Leonid Kruglyak with Curt Stern Award

Leonid Kruglyak, a renowned geneticist, received the 2015 Curt Stern Award for his pioneering work on understanding gene interactions and genome-wide association studies. His laboratory has developed powerful model organisms for studying complex genetic variation.

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Genes responsible for increased activity during the summer

A study by the University of Leicester reveals that a thermosensory gene called TrpA1 is linked to changes in behavior in flies during warmer climates. The research suggests that this gene plays a crucial role in regulating the biological clock, which is essential for controlling circadian rhythms.

What droppings can tell us

Scientists used genetic analysis of otter droppings, known as spraint, to estimate the size of the population. They found around 20 otters living in a 35-square-kilometer area, with numbers fluctuating depending on pond yields.

A genetic approach to understanding addiction

A new study led by Dr. Jinbo Bi at the University of Connecticut School of Engineering aims to find the genetic causes of specific symptoms of substance addiction. The study will use a database of over 11,000 subjects and develop new statistical tools to classify substance dependence more effectively.

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From worker to queen at the drop of a gene

Biologists from the University of Leicester have discovered that buff-tailed bumblebees develop into queens or workers based on gene expression. The study found that differentiation is not caused by inherited genetic differences, but rather by distinct expression patterns in adults.

Scientists create mice with a major genetic cause of ALS and FTD

Researchers have successfully created mice that mimic the symptoms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two devastating neurodegenerative disorders. The mice exhibit key hallmarks of the diseases, including toxic RNA clusters and TDP-43 protein inclusions.

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Genes may influence leadership in the workplace, research finds

A study by Kansas State University researchers found that genes can influence leadership in the workplace, with both positive and negative effects. People with a certain allele of the dopamine transporter gene were more likely to engage in mild rule-breaking behavior, which is positively associated with leadership. However, those with ...

Geneticists clock genetic differences between 'larks' and 'owls'

A new study by geneticists from the University of Leicester has identified nearly 80 genes associated with 'morningness' and 'eveningness' in fruit flies. This discovery could lead to better diagnostics and personalized medicine, where individuals receive tailored therapies based on their unique genetic profiles.

Scientists reconcile three unrelated theories of schizophrenia

Researchers have reconciled three unrelated hypotheses about schizophrenia's causes by studying mice with a genetic deletion. The findings suggest that faulty neural connections, excess dopamine, and brain pruning are linked to the disease. The study aims to develop treatment strategies targeting these underlying causes.

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Gene loss creates eating disorder-related behaviors in mice

Researchers found that mice lacking the estrogen-related receptor alpha gene exhibit abnormal behaviors related to eating and social interactions. The study identifies ESRRA as a key gene contributing to the risk of anorexia nervosa, with implications for treating the disorder.

Mutation causes mice to behave as if they have an eating disorder

A genetic mutation associated with an increased risk of developing eating disorders in humans has been found to cause obsessive-compulsive-like behaviors and social impairments in mice. The study identified estrogen-related receptor alpha as a contributing gene to the risk of anorexia nervosa or bulimia nervosa.

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