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Startled flies may provide insight into ADHD

Researchers discovered two independent forms of arousal in fruit flies, with one mutation linked to increased startle response and decreased endogenous arousal. The findings suggest that environmentally stimulated arousal and sleep-wake transitions reflect distinct neural circuits, potentially shedding light on the neurobiology of ADHD.

SourceCell Press·JournalNeuron·DateNov 25, 2009

Alcohol tolerance 'switch' found

Researchers at North Carolina State University discovered a genetic 'switch' in fruit flies that contributes to increased alcohol tolerance. This switch also has implications for the development of fatty liver syndrome and cirrhosis in humans, with certain gene variations linked to excessive drinking behavior.

SourceNorth Carolina State University·JournalGenetics·DateOct 21, 2009

Scientists demonstrate link between genetic defect and brain changes in schizophrenia

Researchers at UNC School of Medicine discovered a genetic lesion associated with schizophrenia disrupts brain development, altering neuron numbers and GABAergic cell placement. This finding supports the neurodevelopmental hypothesis, offering new avenues for understanding the disease's molecular mechanisms and potential biomarkers.

SourceUniversity of North Carolina Health Care·JournalProceedings of the National Academy of Sciences·DateOct 16, 2009

Stanford scientist's new findings of autism-associated synapse alterations lead to coveted NIH grant

A Stanford University researcher has pinpointed the mechanism by which a gene associated with both autism and schizophrenia influences behavior in mice. The study identified behavioral changes in the mice similar to some symptoms of autism and schizophrenia, highlighting the complexities of cognitive disorders.

SourceStanford Medicine·JournalProceedings of the National Academy of Sciences·DateOct 12, 2009

Self-sacrifice among strangers has more to do with nurture than nature

Researchers found that culturally learned behaviors are a better explanation for altruism than genetics. Altruism was more common in neighboring social groups with similar cultural practices, suggesting a gene-culture coevolution of prosocial propensities. This challenges traditional views on the role of nature versus nurture in shapin...

SourceU.S. National Science Foundation·JournalProceedings of the National Academy of Sciences·DateOct 12, 2009

Study finds human population expanded during late Stone Age

A study found that human populations began to expand in size in Africa around 40,000 years ago, supporting the hypothesis that population growth played a significant role in the evolution of human cultures. The research used genetic evidence and computational approaches to simulate the evolution of genetic lineages over time.

SourcePLOS·JournalPLOS ONE·DateJul 28, 2009

Genetic marker linked to problem behaviors in adults with developmental disabilities

Researchers found a common genetic variation linked to aggression and destructive behavior in adults with developmental/intellectual disabilities. The study suggests that this variation may be associated with increased autism severity in individuals with the gene variant, highlighting the need for further research.

SourceVanderbilt University·JournalAmerican Journal on Intellectual and Developmental Disabilities·DateJul 21, 2009

Further gene mutations linked to autism risk

Researchers found rare copy number variations in genes of children with autism spectrum disorders but not healthy controls. The study identified two novel genes, BZRAP1 and MDGA2, thought to be important in synaptic function and neurological development.

SourcePLOS·JournalPLOS Genetics·DateJun 26, 2009

Good males are bad fathers

A new study on seed beetles reveals that low genetic quality males are more successful in fertilizing eggs, contrary to predictions. Females' multiple mating does not guarantee the sperm of the highest genetic male.

SourceUppsala University·JournalScience·DateJun 25, 2009

Mosquito evolution spells trouble for Galapagos wildlife

Researchers discovered that the Galapagos giant tortoise and marine iguana are targeted by mosquitoes feeding on reptile blood, raising fears of devastating native wildlife diseases. The mosquito's adaptation to life in Galapagos could enable rapid spread of new diseases due to the islands' lack of immunity.

SourceUniversity of Leeds·JournalProceedings of the National Academy of Sciences·DateJun 1, 2009

Family-based program helps youth avoid risky behavior -- even those who may be genetically prone to it

A new study demonstrates that a family-based prevention program can protect youth from engaging in risky behaviors, even if they have a genetic risk factor. The program, called 'Strong African American Families', taught parents and children skills to promote positive goals, emotional support, and racial pride.

SourceSociety for Research in Child Development·JournalChild Development·DateMay 15, 2009

Genetic basis for migration

Scientists have identified a set of genes involved in orienting Eastern North American monarch butterflies' internal 'sun compass' and driving their 4000km migration to Mexico. The research reveals seasonal changes in genomic function help define the migratory state, independent of juvenile hormone activity.

SourceBMC (BioMed Central)·JournalBMC Biology·DateMar 30, 2009

To swim or to crawl: For the worm it's a no brainer

Researchers at the University of Leeds have discovered that C. elegans worms can exhibit both swimming and crawling behaviors, challenging the long-held assumption that these are distinct gaits. The study's findings suggest that a single underlying nervous system mechanism controls a range of locomotion behaviors.

SourceUniversity of Leeds·JournalHFSP Journal·DateMar 30, 2009

Texas-sized tract of single-celled clones

A Rice University study has confirmed a world-record colony of amoebae clones measuring at least 12 meters across in a Texas cattle pasture. The discovery provides insights into the evolution of cooperative behavior in microorganisms like Dictyostelium discoideum.

SourceRice University·JournalMolecular Ecology·DateMar 11, 2009

2 genes influence social behavior, visual-spatial performance in people with Williams syndrome

Study finds GTF2IRD1 contributes to visual-spatial performance while GTF2I plays a role in social behavior, shedding light on complex aspects of human behavior. The research used genetic analysis to identify the genes' effects on cognitive abilities and behavior, providing new insights into Williams syndrome.

SourceUniversity of Utah Health·JournalAmerican Journal of Medical Genetics·DateFeb 11, 2009