Researchers at the University of Pittsburgh Medical Center have identified 19 genetic loci associated with depressive disorders, which may lead to more effective treatments. The study also found that individuals with these genes had a significantly reduced lifespan, particularly in children.
Researchers found HIV integrates into human chromosomes near active genes, which are triggered by the virus itself. This targeting specificity could improve gene therapies by leveraging a retrovirus's efficiency.
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Researchers are using nature's existing engineering networks to develop more efficient and sustainable methods for engineering organisms. This approach allows for the introduction of desirable traits without stressing the organism, making it a promising area of research for biosensors, enzyme development, and future medical applications.
Researchers have identified 22 genes essential to the operations of the body's internal clock, which synchronize behavior and physiology with a near 24-hour cycle. The study found that these genes influence the expression of other genes throughout the body, controlling behaviors like sleep and wakefulness.
Hebrew University and Ben-Gurion researchers found that stress causes a shift in gene products, resulting in an oversensitive electrical response in neurons. This could lead to improved treatment options for patients taking drugs that affect the nervous system.
Research investigates how tumor suppressor genes are methylated during development, affecting cancer risk. The study reveals complex interactions between epigenetic regulation and cellular differentiation.
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Researchers found protein Nrd1 helps RNA polymerase II recognize 'stop sign' for certain genes. This mechanism may help understand HIV's hijacking process and fundamental mechanisms of regulating gene expression in yeast.
A study published in Nature Genetics identified the T-box 22 gene as the cause of a rare form of cleft palate. The gene's mutation leads to catastrophic effects on protein production, resulting in the birth defect. The discovery may lead to prenatal therapeutic interventions for cleft palate.