Articles tagged with Genetic Circuits
Scientists have developed a novel gene transfer technique that selectively eliminates a specific neural circuit in non-human primates. The 'elimination' of the basal ganglia's hyperdirect pathway reveals its crucial role in motor function and provides insights into Parkinson's disease mechanisms.
Researchers designed a synthetic genetic circuit that creates a striped pattern, using genes from one species of bacterium and inserting them into another. By controlling the rate at which cells move, they can create distinct patterns with concentric rings of crowded and dispersed bacterial cells.
Researchers have identified a specific gene circuit that acts as a 'switch' to tell cells when to divide. This discovery may help scientists better understand cell biology and establish a library of cancer-causing pathways.
UT Southwestern researchers discovered that bacteria employ genetic circuits to generate diversity, increasing their chances of survival in unpredictable environments. This diversity allows individual bacteria to thrive under certain conditions, while others struggle, much like a diversified investment portfolio.
Researchers at Duke University discovered that some bacteria exhibit bistability, allowing individual cells to respond differently to external commands. This phenomenon enhances the efficiency of synthetic circuits, which could produce proteins, chemicals, or deliver targeted drugs.
Researchers have developed cells that can count up to three cellular events, mimicking computer chips with simple circuits. The RTC Counter uses a series of genes activated in a specific order, while the DIC Counter stores digital memory by encoding 'bits' of information.
A team of Boston University researchers has developed a new method for engineering genetic circuits using combinatorial libraries and computer modeling. This approach enables the rapid construction of gene networks with predictable behaviors, accelerating synthetic biology research. The technique involves creating libraries of diverse ...
Three Caltech researchers, David Chan, Michael Elowitz, and Grant Jensen, were selected as new HHMI investigators. They will focus on mitochondrial dynamics, genetic circuits, and biological imaging to advance scientific knowledge dramatically. The selection brings the total number of HHMI investigators at Caltech to 10.
Researchers created OCD-like behaviors in mice using genetic engineering and reversed them with antidepressants and targeted a key brain circuit. The study suggests new strategies for treating the disorder by understanding the role of the SAPAP3 gene in glutamate-mediated communications.
Researchers found that a defect in RGS4 gene may cause schizophrenia-like symptoms, such as difficulty filtering out unimportant sensory information. The study uses mouse brain nerve cell circuitry to better understand the cause of schizophrenia.
Researchers found that monkeys with impaired dopamine receptors were more productive and accurate in their tasks, while those without the receptors procrastinated. The study uses a gene knockdown technique to deplete D2 receptors, leading to improved performance.
Researchers successfully engineered a genetic toggle switch to control the activity of genes between stable on and off states. The toggle represents core technology for genetic control devices with potential applications in diabetes, biological warfare agent detection, and cell-based computing.
Scientists from the University of Wisconsin-Madison describe a genetic trick that helps explain the diversity of patterning and color on butterfly wings. This trick is also believed to be used among animals, enabling the emergence of new morphological characteristics through evolution.