Articles tagged with Genome Evolution
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The study recovers 8,280 bacterial and 623 archaeal genomes from environmental samples, increasing the number of known life forms by nearly 10%. This represents a significant boost to our understanding of microbial diversity and its role in critical biogeochemical processes.
The California Academy of Sciences has assembled the first-ever animal genome of the northern spotted owl, a threatened species. The completed genome will help researchers track interbreeding between hybrid owls and inform conservation priorities in the West.
A new type of plant, 'Shetland's monkeyflower', has been discovered in the Shetland Isles, resulting from the doubling of its chromosomes. The plant, a descendant of a non-native species, produces larger flowers and changes in leaf size and flowering time.
Researchers sequenced and compared apple genomes to reveal a two-way journey for domesticated apples along the Silk Road. The study pinpointed the origin of domesticated apples in Kazakhstan and discovered that they hybridized with local wild apples, yielding modern dessert apples.
Scientists have uncovered the secret behind goldfish's remarkable ability to produce alcohol as a way of surviving harsh winters. The fish convert anaerobically produced lactic acid into ethanol, allowing them to avoid dangerous build-ups in their bodies.
Researchers mapped evolutionary turning points that transformed a fungus with tens of thousands of mating types to one with only two. They found that translocations brought together separate chunks of sex-determining genes onto a single chromosome, mimicking the human X or Y chromosome.
Researchers at Rockefeller University created genetically altered ants to explore the evolutionary roots of ant social behavior. The study found that a gene essential for sensing pheromones is crucial for pheromone detection and social organization, leading to behavioral abnormalities in mutant ants.
A study found that San Salvador pupfish acquired genetic variation from island fish, contributing to the evolution of specialized diets. The research identified 11 gene variants in the San Salvador fish genome that came from other Caribbean pupfish populations.
Researchers have discovered a whole genome duplication in the evolution of spiders and scorpions, suggesting they shared an ancestor over 400 million years ago. This event is thought to have led to changes in gene expression, contributing to the diversification of these species.
A new study reveals that certain microorganisms in symbiotic relationships are constantly being replaced and discarded by their hosts. The researchers found that the genome of these microorganisms undergoes significant changes, losing genes over time and ceasing to be useful to the host.
A new phylogenetic tree resolves key relationships among vertebrates, including the identification of lungfishes as closest living relatives of land vertebrates. The study uses a novel set of analyses for building large-scale genomic datasets.
The sequencing of Porphyra's genome revealed minimal structural elements in its cellular cytoskeletons, allowing it to thrive in extreme environments. The analysis also uncovered genes for UV protection and compounds that enable the organism to withstand desiccation.
A recent study published in Genome Biology and Evolution proposes that only 10-15% or up to 25% of the human genome is functional, with the remaining portion consisting of non-functional 'junk DNA'. This finding contradicts previous estimates suggesting 80% of the genome has a biochemical function.
Researchers have discovered that mammalian cells can build an embryo by making four simple decisions, including counting their neighboring cells. This simplified understanding of embryonic development challenges traditional theories and offers new insights into evolution.
The study found that the red vizcacha rat's genome grew quickly due to the expansion of highly repetitive elements, rather than whole genome duplication. This mechanism is also thought to contribute to 'genomic baggage' in humans, influencing disease susceptibility.
A study by Babraham Institute and Weizmann Institute reveals genes are constantly rearranged in cells, changing their positions to fine-tune gene expression. Researchers collected data from over 4,000 individual cells using single-cell Hi-C technology, providing unique insights into genome organisation.
A new study analyzed flu samples from four transplant patients with long-lasting infections, revealing certain viral changes that matched global flu evolution trends. The researchers found that some mutations fixed in these patients would eventually take over the worldwide population of viruses.
Scientists at UC Berkeley and UC Riverside have developed a gene editing technique using CRISPR/Cas9 technology to suppress mosquitoes carrying diseases like malaria. The new technique, multiplexing, can target multiple locations in a gene simultaneously, increasing the effectiveness of gene drive systems.
Scientists used an evolutionary medicine approach to estimate Alzheimer's disease causative genes by focusing on ohnologs, duplicated genes vulnerable to change in number. The study successfully identified a group of genes related to the nervous system and high brain expression levels similar to known AD-causative genes.
A new study found that cells can adapt to environmental changes more rapidly by accelerating genetic changes around genes that boost fitness. By increasing the number of copies of genes, cells can synthesise more protein product, making processes more efficient.
Researchers at UNIGE show that Fprs, present on immune cells, also bind to molecules linked to pathogens in the nose of mice, indicating an evolutionary shift towards olfaction. This innovation resulted from two genomic 'accidents' occurring millions years apart during rodent evolution.
Scientists study Burmese pythons' ability to regenerate organs after feeding, identifying key genes that drive regenerative growth. The team also explores the genetic basis of evolution in snakes and lizards, shedding light on the mechanisms behind unique traits such as venom composition and reproductive differences.
Researchers computationally recreated ancient chromosomes of the first eutherian mammal, revealing chromosomal changes that occurred over 105 million years. The study provides a detailed picture of evolutionary breakpoints and their role in forming new species and contributing to human diseases like cancer.
Rachel Whitaker, Associate Professor of Microbiology at the University of Illinois, receives a $1.5 million award to study mobile genetic elements and their role in microbial evolution. Her research aims to develop a new evolutionary paradigm to combat antimicrobial resistance.
Researchers identified natural genomic variation in Cryptococcus neoformans, influencing prevalence and disease severity. The study found specific variants associated with clinical isolates linked to known virulence factors.
A team of biologists found that a promiscuous salamander balances its genome by using equal contributions from three separate species. This balanced genetic profile may be key to the hybrid's success and adaptability.
A group of scientists found that parasitic nematode species can thrive without sex by using large, duplicated genomes. These genomes provide a reservoir for adaptation to different environments and plant hosts, giving the nematodes an evolutionary advantage over their sexual relatives.
Research reveals that nutritional factors significantly impact genetic variation and mutation patterns in bacteria, leading to distinct evolutionary paths. Environmental stresses like starvation for essential elements determine the availability of mutations, influencing the emergence of traits dependent on specific mutations.
Rotifers have been found to use Terminons, giant DNA sequences, to shield their chromosomes from degradation, which is linked to aging. This finding may help researchers better understand the mechanisms of aging.
Researchers from Arizona State University have decoded the Mojave Desert tortoise's genome, which could aid in its survival by understanding genetic adaptations to disease and harsh environmental conditions. The study's findings may also inform conservation strategies to preserve this threatened species.
Researchers from the University of Bristol found that a recently developed molecular clock method called RelTime failed to relax the clock, sparking debate on the age of animals. The team's findings suggest that animals are unlikely to be older than approximately 850 million years, in agreement with previous studies.
A team of scientists has provided a new evolutionary tree for Archaea, resolving their deepest relationships. The study suggests that early Archaea likely used the Wood-Ljungdahl pathway to make energy, dating back over 3.5 billion years.
The sunflower genome sequence provides insights into oil metabolism, flowering time, and Asterid evolution. The research identifies new candidate genes and reconstructs genetic networks controlling these traits.
A research team led by UNM Associate Professor Coenraad Adema has sequenced the genome of Biomphalaria glabrata, a tropical snail that transmits a deadly parasitic disease. This breakthrough could lead to the elimination of schistosomiasis, which kills hundreds of thousands of people annually.
Scientists discovered that humans are able to keep accumulating damaging mutations in check due to the synergistic interactions between different parts of the human genome. This study provides evidence for natural selection against highly damaging genetic mutations and sheds light on the evolutionary maintenance of sexual reproduction.
A recent study utilizing genomic big data analyzed the silver birch genome, uncovering population bottlenecks and speciation events that shaped the species' current form. The research also identified genes under natural selection, which have contributed to birch's cold tolerance and rapid growth.
Researchers have developed a new tool called ModelFinder to study the evolution of proteins. The program allows for more accurate scientific estimates of evolutionary processes, which will help unravel the mysteries behind life's diversity on Earth.
A recent study identified around 6,500 human genes that are expressed differently in men and women, with some genes playing a crucial role in body hair growth, muscle building, and fat storage. The research suggests that natural selection puts less pressure on genes specific to one sex or the other.
Researchers found that new genes are more likely to appear in full form rather than gradually evolving through proto-genes. This is because non-coding DNA sequences give rise to highly ordered proteins, which are often deleterious to the organism.
The study maps the evolution of dog breeds using gene sequences from 161 modern breeds, uncovering evidence of ancient canine migration across the Bering land bridge. The research also sheds light on the origins of various breeds, including herding dogs and hairless breeds.
Researchers found that early mammalian ancestors enhanced their night vision genes, allowing them to thrive in the dark. This study supports existing fossil evidence and sheds light on the evolution of vision in mammals.
Researchers found that different genes influence behaviors in males and females, and the gene for vasopressin is closely tied to nest-building behavior in mice. The study challenges the idea that experience drives parenting behavior and suggests that genetics play a significant role.
Researchers have unlocked genetic information about lettuce and related plants, releasing the first comprehensive genome assembly for lettuce and the Compositae family. The study found that triplicate genes may explain the success of this huge plant family.
Researchers found that cephalopods use RNA editing extensively, with over half of their transcribed genes being edited. This process has profoundly constrained the evolution of the cephalopod genome.
A new group of giant viruses, dubbed Klosneuviruses, has been discovered with a more complete set of translation machinery genes than any other virus known to date. These viruses are thought to have evolved from smaller viruses and encode proteins involved in protein biosynthesis, expanding our understanding of viral evolution.
Scientists uncover a potent genetic element in microorganisms that enable them to self-mutate, expanding the diversity of the tree of life. The discovery reveals how rapid evolution happens in some of Earth's smallest and most common microbes.
Researchers found that mitochondrial-nuclear interactions affect energy production in animal cells, leading to variations in traits and potentially influencing human health. The study suggests that metabolic fitness relies on these interactions, which have significant implications for physiology and medical interventions.
A new study analyzed 41 genomes to determine how Cyanobacteria evolved oxygenic photosynthesis, finding that it likely occurred through lateral gene transfer in Oxyphotobacteria after divergence from the Melainabacteria group around 2.5-2.6 billion years ago
Researchers discovered that the herpes virus family evolved independently but also showed signs of recombination with HSV-1, which occurred between 34,000-95,000 years ago. This challenges previous theories on human migration and origins of STDs.
Researchers found that HIV co-infections drive natural selection in M. tuberculosis, favoring epitope conservation and influencing its evolution. This discovery has implications for vaccine design to combat the co-epidemic in high-HIV TB settings.
A family of ~350 human proteins has been found to establish complex interplay with transposable elements, creating largely human-specific gene regulatory networks. These networks influence all of human biology, both in health and disease, and are likely to have profound implications for understanding human development and physiology.
Scientists have examined the globin gene cluster in zebrafish to understand 3D genome folding and its relationship to gene expression. They found that adult and embryonic globin genes are spatially separated in the genome, with distinct chromatin domains and organization.
Researchers found that genetic variants linked to autism spectrum disorders are also associated with enhanced cognition and intellectual achievement, suggesting positive selection during human evolution. The study analyzed over 5,000 cases of ASD and identified common variants that contribute to both conditions.
A recent study by Indiana University researchers found that the master gene doublesex plays a complex role in controlling the expression of physical differences between males and females. The study reveals new details about how this gene influences traits such as genitalia, brain development, and ornamentation.
Researchers sequenced over 1,000 stick insect genomes to study early phases of speciation, finding that genetic differences across the genome are crucial for distinguishing between species. The study suggests that rapid reversals of speciation can occur when distinct species cross paths again.
A University of Wyoming researcher and her team have discovered that the rapid evolution of Lake Victoria cichlids was facilitated by earlier hybridization between two distantly related species. This phenomenon has resulted in over 700 species of fish evolving in just 150,000 years.
A team of researchers from Universitêl Laval cast doubt on the idea that genetic redundancy makes organisms more resilient to genetic perturbations. They found that paralogous genes in bread yeast were more often necessary for cellular function than previously thought, highlighting a potential vulnerability to mutations.
A new study found that most vertebrate genomes exhibit dynamic behavior, with some species losing and gaining DNA over time. This study provides the first comprehensive comparison of warm-blooded vertebrates, revealing surprising similarities between birds and mammals.
A four-year genetic research effort has mapped the major landmarks in the evolution of dinoflagellates, a key species in the environment. The study found that nonphotosynthetic dinoflagellates have retained vital metabolic functions and could lead to a better understanding of bioluminescence and toxic algal blooms.
A new method for filtering genetic study results has been developed to refine understanding of preterm birth risk factors. The technique, known as evolutionary triangulation, uses ancestry patterns to identify key genes involved in preterm birth.