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Hyperacute Rejection

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Articles tagged with Hyperacute Rejection

Molecular mapping reveals hidden cellular programs in heart transplant rejection

Researchers at Vanderbilt University Medical Center used spatial transcriptomics to characterize acute rejection and response to immunomodulatory therapies following heart transplantation. The study linked cell-specific gene expression patterns to the development of cardiac allograft vasculopathy, a form of chronic rejection that limit...

SourceVanderbilt University Medical Center·JournalNature Cardiovascular Research·TypeImaging analysis·DateAug 10, 2026
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New study finds task switching raises risk in transplant surgeries

A new study from Virginia Tech found that task switching in transplant surgeries increases one-year mortality rates by 14.8 percent, highlighting the need for efficient scheduling and workflow changes to minimize risks. The research also suggests that recovery time and surgeon experience level can mitigate these effects.

SourceVirginia Tech·JournalNature Human Behaviour·DateApr 30, 2026

Discovery from Mass General Brigham researchers yields insights on preventing organ transplant rejection

A new study by Mass General Brigham researchers has identified a natural 'brake' within the innate immune system that can prevent organ transplant rejection. The discovery highlights a promising target for new therapies and offers hope for longer-lasting transplant success and reduced need for lifelong immunosuppression.

SourceMass General Brigham·JournalScience Translational Medicine·TypeObservational study·DateMay 7, 2025

The 10-gene pig and other medical science advances enabled UAB’s transplant of a pig kidney into a brain-dead human recipient

UAB surgeons successfully transplanted a genetically modified pig kidney into a brain-dead human recipient, testing safety and feasibility in a novel human preclinical model. The experiment showed that the xenograft perfused normally and maintained vascular integrity, paving the way for potential treatment of thousands with organ failu...

SourceUniversity of Alabama at Birmingham·JournalAmerican Journal of Transplantation·TypeExperimental study·DateJan 20, 2022
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