Researchers found that ancient retroviruses helped shape p53, a master gene regulator in primates, by inserting DNA sequences and rearranging the genome. This discovery provides new insights into how gene regulatory networks evolved in humans and other primates.
Genomatix Software GmbH has won a $1.6 million BioChance grant to research RNAi mediated regulatory networks. The two-year project will expand its competence in this field, complemented by academic partners from LMU Munich and DKFZ Heidelberg.
Researchers at UCSD found that E. coli exhibits only six distinct functional states regardless of the carbon source or electron acceptor used, suggesting a surprising level of simplicity in its metabolic processes. The study suggests that this principle may be generalizable to other species.
Yale researchers developed a complex map of regulatory networks governing protein kinase activity in yeast cells. The study reveals distinct patterns and provides insights into the coordination of proteins to carry out complex biological functions.
The team developed a genome-scale computational model of gene regulation in E. coli, uncovering surprising new details about how the cell responds to oxygen deprivation. The model includes 1,010 genes, including 104 regulatory genes, which regulate the expression of 479 genes involved in metabolism.