Articles tagged with Viral Genes
Researchers found a direct evidence of simian virus 40's potential mechanism in the development of mesothelioma, a rare cancer associated with asbestos exposure. The study suggests that SV40 targets key proteins preventing tumors from forming, rendering them ineffective.
A team from the University of Rochester Cancer Center has identified the protein PP1c that activates the retinoblastoma (RB) gene, a key tumor suppressor. This finding offers a new avenue for controlling cancer cell growth and potentially treating various types of cancer.
Researchers at the University of Rochester have created a gene control technology that allows for permanent gene modification in adult mice. This breakthrough enables scientists to study nearly any gene in the nervous system with unprecedented control and precision.
Scientists have discovered a basic gene-for-gene resistance mechanism in plants, triggered by the interaction of proteins produced by both a resistance gene and an avirulence gene in the disease-causing microorganism. This finding has wide application for understanding how plants identify and resist diverse pathogens.
Scientists confirmed decades-old notion that plant disease resistance is linked to protein interaction between a plant's resistance gene and a pathogen's avirulence gene. The discovery may lead to genetically engineered disease-resistant crops, as researchers suspect the mechanism occurs in many other plants.
Researchers at NIAID have determined the entire genetic sequence of molluscum contagiosum virus (MCV), which causes persistent and sometimes disfiguring skin lesions in HIV-infected individuals. The complete DNA sequence will enable testing of drugs against MCV genes and studying how the virus evades immune responses.
Researchers found that the cholera pathogen acquired its deadly factors by picking up genes from a virus, CTX phage. The virus instructs the bacterium to introduce the cholera toxin gene, allowing it to become a pathogen.
Researchers discovered that a malfunctioning gene, M6P/IGF2r, acts as a tumor suppressor in human liver tumors. The gene's loss or mutation may predispose cells to cancerous growth, leading to the formation of liver cancer. This finding could lead to the development of early diagnostic tests and new treatments for the disease.