Articles tagged with Bacterial Dna
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A study by NYU College of Dentistry and Weill Cornell Medicine found that older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta, a key biomarker for Alzheimer's disease. The researchers suggest that high levels of 'good' bacteria may be protective against Alzheimer's.
A study published in Frontiers in Molecular Biosciences found that certain types of equine gut bacteria produce chemical signals that communicate with the mitochondria in horse cells, delaying low blood sugar and inflammation. This discovery paves the way for dietary supplements to enhance equine athletic performance.
Researchers uncover how tailocins, produced by bacteria under stress, target specific strains with lethal precision. The nanomachines have potential applications in studying microbial interactions and developing new antibiotics.
The Mfd protein's dual role in repairing bacterial DNA and promoting mutations has been discovered, offering new avenues for fighting antibiotic resistance. This phenomenon could also lead to a better understanding of cancer cell resistance to chemotherapy.
Researchers developed a new method to detect multiple types of DNA methylation in individual bacteria and the gut microbiome using nanopore sequencing. This breakthrough enables reliable methylation discovery and high-resolution microbiome analysis.
Researchers have discovered that plants influence how their bacterial and fungal neighbors react to climate change. The study found that simulated drought affected both bacteria and fungi in grassland and scrubland, while nitrogen addition had a lesser impact on bacteria, but more significant effects on the overall microbial diversity.
Researchers have identified seven genes essential for normal cell division, allowing a synthetic cell to grow and divide uniformly. This breakthrough aims to engineer synthetic cells for various applications, including drug production, disease detection, and computing.
A toxic cyanobacterial neurotoxin, aetokthonotoxin, causes vacuolar myelinopathy (VM) in bald eagles and their prey, linked to invasive aquatic plants. The toxin is produced when herbicides containing bromine stimulate its formation on plant leaves.
Researchers at MSU used transposons to tag individual strains of Brucellosis bacteria, allowing them to track the spread of the disease in cattle. The study provided critical insight into the cow's mucosal barrier and identified genes involved in severe outcomes.
A study found that deforestation in the Amazon leads to an increase in antibiotic-resistant soil bacteria, with a larger number of genes and molecular mechanisms detected in deforested areas than in forested ones. The researchers warn that these microorganisms can pose a significant public health risk if they reach humans.
Scientists have pinpointed a critical mechanism allowing deadly bacteria to resist antibiotics, and discovered a potential new target for effective treatment. The study identified quinolone antibiotic resistance mechanisms, including the production of pentapeptide repeat proteins, and revealed how they inhibit bacterial enzymes.
Bacteria use a carbohydrate slime to resist antibiotics and thinning agents used in cystic fibrosis treatments. The slime creates a protective layer around the bacteria, making them harder to kill.
The CUHK research team found that viscoelasticity can be harnessed to control active matter's self-organisation, enabling the creation of self-driven devices. The discovery has implications for soft robotics, tissue engineering, and microbial physiology, as well as the dispersal of biofilms and gut microbiome.
Scientists identified how harmless E. coli gut bacteria in chickens can acquire genes to become life-threatening infections, highlighting the potential for horizontal gene transfer and increasing antibiotic resistance. The study warns of the risk of such infections crossing over to infect humans.
Scientists at University of Warwick and Monash University discovered the molecular basis of a biological mechanism controlling antibiotic production in soil bacteria. This breakthrough could lead to improved manufacturing of existing antibiotics and uncovering new ones.
Researchers aim to understand the form and function of dry biofilms using probiotic cleansers. They hope to demonstrate how friendly bacteria interacts with bad bacteria and remove dry biofilms without harsh chemicals.
Researchers have discovered that toxin-antitoxin (TA) systems play a crucial role in plasmid replication and bacterial antibiotic resistance. The presence or absence of plasmids significantly impacts a bacterium's ability to cause infection.
Researchers at Johns Hopkins Medicine discovered that the gene-cutting system CRISPR-Cas9 can be used as a genetic dimmer switch, allowing scientists to develop new ways to genetically engineer cells. The long form of tracrRNA was found to repress CRISPR-related genes and protect bacteria from excessive activity.
Researchers have developed a DNA test to identify secondary infections in COVID-19 patients with severe cases, who are at double the risk of developing pneumonia on ventilation. The test allows for faster diagnosis and targeted antibiotic treatment within hours, reducing unnecessary use of antibiotics.
Scientists from the University of Copenhagen have created an AI-powered method to study the complex gut microbiome by analyzing faeces. The technique can help identify patterns in bacterial composition and connection to diseases like diabetes and autism.
Researchers discovered a novel mechanism by which mycolic acid-containing bacteria form diverse types of membrane vesicles in response to DNA damage and envelope stress. This finding provides insight into the mechanisms of membrane vesicle formation, which could be helpful for developing novel therapeutics or vaccines.
Engineered living materials (ELMs) are created using a symbiotic combination of yeast and bacteria, similar to those found in kombucha SCOBY. These ELMs can detect and filter contaminants in water, packaging, and act as 'living photographs' displaying projected images.
Researchers discovered that random DNA sequences can generate new genes producing antibiotic resistance, which can spread quickly among bacteria. The study used laboratory experiments with E. coli and found six peptides causing Colistin resistance by modifying the cell membrane.
Scientists have found that nearly all antibiotic resistance genes came from bacteria that cause disease, not antibiotic-producing bacteria. The rapid evolution of resistance is fueled by the use and overuse of antibiotics, threatening modern healthcare.
A recent study published in Genome Biology reveals a high level of site-specificity in bacteria found in the human mouth, with distinct genetic forms associated with specific sites. The researchers used metapangenomics to identify novel bacterial strains and potential habitat-specific genes.
Researchers discovered a unique evolutionary event in which an antibacterial enzyme in ticks protects them from bacteria on human skin while allowing the Borrelia burgdorferi bacterium to thrive. The ticks acquired this gene 40 million years ago through horizontal gene transfer.
Researchers have discovered two new, compact Cas9 nucleases that can work in human cells and may expand the toolbox for genome editing. The new nucleases have relatively short PAMs, making them suitable for delivery via adeno-associated viral vectors.
A recent study by UC San Francisco researchers reveals that ticks possess an antibiotic gene called dae2, which protects them from contracting pathogens, including Staphylococcus bacteria. This discovery provides new insights into the complex interactions between ticks and human skin microbiota.
Researchers have developed a new method for storing digital information in biological molecules using aerolysin nanopores. This technology has the potential to revolutionize data storage by offering high accuracy, low costs, and compactness.
Researchers at Karolinska Institutet discovered a link between non-coding RNA mutations in the Neisseria meningitidis bacterium and severe invasive meningococcal disease. They also developed a PCR test to detect these mutations, which may aid in speedy identification and treatment.
A new study by UC Riverside and Pacific Northwest National Laboratory has revealed how bacteria control metabolic intermediates, enabling more efficient biofuel production. By understanding this regulation, scientists can design cells that produce desired chemicals while preventing excessive buildup of unwanted products.
A research team at Friedrich-Schiller-Universitaet Jena has identified a small ribonucleic acid that influences the antibiotic-resistance of Vibrio cholerae. The protein CrvA plays a crucial role in maintaining cell form and is essential for survival on contact with penicillin.
A Canadian team has developed an inexpensive molecule to fight antibiotic-resistant strains of Neisseria gonorrhoeae and N. meningitidis, two bacteria responsible for gonorrhea and meningococcal meningitis. The molecule's specificity allows it to target pathogenic Neisseria while leaving other types unaffected.
Researchers analyzed seven Da Vinci drawings using Nanopore sequencing, finding a dominance of bacteria over fungi, with many exhibiting human or insect microbiomes. The study also identified human DNA, likely introduced by restoration workers, and correlations with geographical location.
Researchers at San Diego State University have uncovered a crucial clue to the mystery of TB's rapid resistance to antibiotics. They found that the pathogen uses an epigenetic domain to diversify and create multiple subpopulations with varying phenotypes, leading to drug resistance.
Researchers have shed light on the atomic resolution structure of the phage DNA tube, a crucial component of phage therapy. The 3D structure reveals a hollow tube with flexible linkers, allowing negatively charged DNA to pass through smoothly. This study marks a significant milestone in integrated structural biology.
A single clinical laboratory test has been developed to detect any infection from any body fluid, without special handling or processing. The test employs powerful DNA-sequencing technology and relies on specially developed analytical software to compare DNA sequences in the sample to massive genomic databases.
Biomedical engineers at Duke University have developed a new model that predicts the persistence of genetic packages in bacterial populations. The model, dubbed 'persistence potential,' uses five variables to determine whether a plasmid will thrive or fade away.
A new study found that plastic bottles colonize with diverse bacterial communities, while elevated CO2 levels negatively impact certain species. Researchers warn of the increasing threat posed by plastics and ocean acidification to marine biodiversity.
Researchers at the Weizmann Institute of Science reveal retrons, hybrid structures found in many bacterial species, are 'guards' that prevent viruses from spreading. These retrons activate a programmed cell death mechanism to protect the bacterial colony.
A new study has uncovered DNA evidence of Bartonella quintana, the bacteria responsible for trench fever, in civilian remains dating back thousands of years. The discovery sheds light on the complex history of trench fever and provides insight into the lives of Christian citizens in Roman Syracuse.
A new study has identified two types of bacteria that can provide protection against radiation exposure by increasing production of propionate and tryptophan. These metabolites were found in leukemia patients undergoing radiotherapy, suggesting a potential alternative to expensive and potentially harmful treatments.
A study published in Nature Microbiology reveals that drug-resistant E. faecium can spread within hospitals despite deep cleaning, with high rates of infection found in vulnerable patient groups. The bacteria's ability to evade cleaning measures poses a significant challenge to infection control.
A new CRISPR-Cas3 tool allows for larger DNA edits, enabling researchers to study disease and normal function in humans and other organisms. This advancement will facilitate the development of new treatments and improve our understanding of the human microbiome.
A new study analyzed DNA from medieval latrines in Jerusalem and Riga, Latvia, providing insights into the microbiomes of pre-industrial agricultural populations. The findings highlight the value of ancient latrines as sources of bio-molecular information and may provide context for interpreting modern microbiome health.
A new study characterizes the microbial diversity of ancient gut contents from medieval latrines, providing insights into pre-industrial agricultural populations' microbiomes. The research highlights the value of ancient latrines as sources of bio-molecular information, shedding light on the health of modern microbiomes.
Researchers have identified a new virus, BV01, that infects a significant portion of the human gut microbiome, leading to changes in bacterial gene expression. The study reveals how the virus disrupts normal gut function and affects human health and disease.
Researchers found viral sequences associated with choanozoans and picozoans, which were not linked to bacterial DNA, suggesting these protists eat viruses. The removal of viruses from the water could potentially reduce the number of viruses available to infect other organisms.
A study by Dr. Cox's team reveals that radio-resistance in bacteria can be induced independently of desiccation, with complex genetic mutations and cellular metabolisms affected.
Scientists have developed a new genetic approach to improve biological nitrogen fixation in soybeans by leveraging wild ancestors' genetic diversity. They found that specific genes interact with beneficial microbes to alter the number of nodules a root system forms.
Researchers at East Carolina University identify a highly diverse microbial community on a 1960s shipwreck, with iron-oxidizing bacteria contributing to biocorrosion. The study's findings highlight the need for tailored conservation efforts to address unique environmental factors and materials.
A Rutgers study suggests that bacteria present in the Passaic River may be capable of dechlorinating 2,3,7,8-TeCDD, a toxic byproduct of combustion and chemical manufacturing. This process could potentially decrease the toxin's toxicity over time.
Researchers at University of Queensland have discovered how bacteria share antibiotic-resistance genes, shedding light on the rapid spread of 'superbugs'. The study reveals a mechanism through which plasmids are mobilized and transferred between bacteria, offering potential solutions to combat antibiotic resistance.
A Stanford study reveals that severely ill COVID-19 patients experience immune system paralysis, leading to enhanced inflammation and lung damage. The research identified three molecular suspects associated with lung inflammation and bacterial debris in the blood, suggesting potential therapeutic targets for combating COVID-19.
A machine learning algorithm using high-temporal-resolution growth curves distinguishes bacterial pathogen strains with 92-98% accuracy, predicting antibiotic resistance as well as genetic-based methods. The method has the potential to be faster, simpler, and less expensive than current techniques.
Researchers at Université de Genève discovered that the RNA helicase protein contributes to the synthesis of fatty acids, a crucial component of bacterial membranes. The findings provide insight into golden staph's ability to adapt to changing environments and may lead to new treatment options.
Compounds tested for their potential as antibiotics have demonstrated promising activity against tuberculosis (TB), a deadly infectious disease caused by Mycobacterium tuberculosis. The study found that the compounds exploit well-known targets for drugs, including the bacterial enzyme DNA gyrase.
A study published in Nature Communications reveals the intricate choreography of phage assembly and its impact on bacterial infections. The research provides new insights into the mechanism of action of phages, which could lead to more precise and effective treatments for drug-resistant bacterial infections.
A study found that women taking MHT have a greater variety of beneficial bacteria in their urine, potentially creating conditions that discourage urinary infections. The study also showed that women with recurrent UTIs have fewer types of bacteria in their urine.
Emerging disease has spread to ten US states and South America, infecting over 80% of corn plants in some fields. Research reveals global spread, host range, and potential DNA transfers among strains.