Human Microbiota
Articles tagged with Human Microbiota
“Tell me who your friends are, and I’ll tell you who you are”
Researchers found that microbes actively adjust their behavior to minimize competition and conflict when living together, leading to more efficient coexistence. This discovery provides insights into how diverse microbial communities assemble and persist despite intense competition.
Phage therapy at a turning point: Valencia 2026 to define the next era of antibacterial medicine
The Targeting Phage Therapy 2026 Congress will bring together experts to address clinical, regulatory, industrial, and hospital infrastructure requirements for phage therapy. The congress aims to move phage therapy from promising science to accessible, validated, and deployable medicine.
E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes
A new study found that breast milk helps maintain a balance of beneficial bacteria in babies' developing gut microbiomes, including E. coli and Bifidobacterium. This mutualistic relationship supports healthy infant development and may have implications for future synbiotics.
Antibiotic resistance genes found in newborns within hours of birth, study shows
A study analyzing meconium samples from newborns found high prevalence of antibiotic resistance genes, including those linked to carbapenem resistance. The findings suggest that maternal transmissions and early hospital exposure contribute to the establishment of these genes in the neonatal gut.
Novel treatment protocol developed at the University of Minnesota targets the deadliest cases of C. difficile infection
A new study from the University of Minnesota Medical School demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant C. difficile infection. The treatment protocol achieved a 78% 30-day survival rate among 18 critically ill patients.
Simple blood test could spot dementia years earlier, research shows
Researchers discovered subtle changes in the blood can reveal early signs of cognitive decline caused by chemicals produced by gut bacteria. A blood test may one day transform how we detect dementia, potentially identifying people at risk years before symptoms appear.
Heart disease risk tied to certain molecules made by gut microbes
A study of 2,000+ participants found nine specific gut microbe metabolites associated with coronary heart disease risk. The researchers call for further research into these molecules as potential novel treatments.
Immune cells link lactation to long-lasting health
Recent studies show that T cells support milk production and have lasting effects on maternal health and infant immunity. The review highlights emerging evidence of the crucial role of immune cells in lactation, which can inform strategies to improve maternal and infant health outcomes.
University of Houston scientist helps rethink microbial future of space travel
A global team of scientists, led by University of Houston microbiologist Madhan Tirumalai, has identified the critical role of biofilms in human space exploration. Biofilms could influence astronaut health, drug delivery and space agriculture, while also posing risks to astronaut health.
Personalized predictions of probiotic and prebiotic therapy success by computer models
A new study uses metabolic modeling to predict which probiotics will successfully establish themselves in a person's gut and how prebiotics affect short-chain fatty acid production. The findings demonstrate the utility of these models for personalized probiotic and prebiotic interventions.
Missing microbes in UK infant gut and probiotics highlighted by global microbiome atlas
A global atlas mapping two key gut bacteria has uncovered a treasure trove of bacterial strains adapted to the infant gut, not found in commercial probiotic products. The study reveals region-specific strains that have naturally evolved to thrive in a baby's microbiome, shaped by regional diets and environments.
Eleven genetic variants affect gut microbiome
Researchers identified 11 genetic regions influencing gut bacteria and roles they play, including connections to gluten intolerance, haemorrhoids, and cardiovascular diseases. The study analyzed genetic data from over 28,000 individuals, providing insights into the complex relationship between genes and gut microbiome.
Scientists create ‘smart underwear’ to measure human flatulence
Researchers developed wearable devices that track hydrogen levels in flatus to better understand gut microbial metabolism. The Human Flatus Atlas project aims to establish normal ranges for flatulence production, helping to identify excessive gas complaints and inform dietary interventions.
Fecal microbiota transplantation improves response to immunotherapy in advanced kidney cancer: TACITO study published in Nature Medicine
A new study found that fecal microbiota transplantation can enhance the effectiveness of immunotherapy in patients with advanced metastatic renal cell carcinoma. The research showed improved clinical outcomes, including longer progression-free survival and higher response rates, in patients who received donor-derived fecal microbiota t...
Wild blueberries: New review explores benefits for heart, metabolism and the microbiome
A new scientific review summarizes 12 human clinical trials on the cardiometabolic effects of wild blueberries, finding improvements in blood vessel function and beneficial changes to the gut microbiome. Regular consumption of one cup per day may support overall health benefits.
Infant gut bacteria may be the key to preventing asthma and allergies
Researchers have identified a previously unknown mechanism that can reduce the risk of allergies and asthma in children. Certain bifidobacteria produce a substance called 4-hydroxyphenyl lactate (4-OH-PLA), which dampens immune responses to allergens, reducing the production of IgE antibodies.
Gut bacteria changes at the earliest stages of inflammatory bowel disease
A new international study found significant changes in gut bacteria at the onset of inflammatory bowel disease (IBD), a condition that affects the digestive system. The study reveals a loss of beneficial anaerobic bacteria and an increase in oxygen-tolerant bacteria, which may trigger inflammation.
A fatal mix-up: How certain gut bacteria drive multiple sclerosis
Researchers have discovered that certain gut bacteria with similar structures to the protective layer of nerves can misdirect the immune system and cause it to attack its own nervous system. This mechanism accelerates the progression of multiple sclerosis.
Family dogs boost adolescent mental health through the microbiome
Research suggests that owning a family dog during adolescence can boost mental well-being and social support by altering the gut microbiota. The study found that adolescents with dogs had higher mental health scores and lower social problems compared to those without dogs.
Nasal microbiome: Resource scarcity as opportunity
A study reveals that competition for biotin, a vital vitamin, drives interactions between harmful Staphylococcus aureus and harmless commensal bacteria. This resource scarcity could lead to new strategies for fighting multi-resistant germs.
Medications change our gut microbiome in predictable ways
Research reveals that medications can reshape the trillions of microbes in the gut by competing for nutrients, leading to predictable changes in the microbiome. The study provides a framework for predicting how a person's microbial community might change with a given drug, potentially helping scientists find ways to prevent side effects.
Groundbreaking review reveals how gut microbiota influences sleep disorders through the brain-gut axis
A comprehensive review synthesizes current insights into the intricate connections between gut microbiota and sleep regulation, highlighting the crucial role of peripheral organs in modulating brain function and behavior. Disruptions in gut microbiota composition are closely linked to sleep disturbances across multiple disorders.
Targeting Microbiota 2025: Decoding the microbiome to shape the medicine of tomorrow
The microbiota is recognized as a dynamic organ producing molecules that regulate gene expression, immunity, and mitochondrial function. Biomarkers of inflammation, metabolism, and aging can be predicted through microbiota signatures, establishing the microbiota as a pillar of predictive medicine.
U Iowa study links multiple sclerosis with distinct oral microbiome
Researchers found that people with MS have a distinct oral microbiome compared to healthy individuals, characterized by a loss of beneficial bacteria and an increase in disease-causing bacteria. The study suggests that oral microbial and metabolic changes may contribute to inflammation and disease processes in MS.
Dusty air is rewriting your lung microbiome
Scientists found that breathing dusty air from the Salton Sea can alter the lung microbiome and trigger immune responses in mice. The study suggests that chronic exposure to such dust could have significant health effects, including asthma.
Genetics pioneer transforms global depression research through multi-omics discoveries
Dr. Amin's transformative insights reshape international understanding of depression genetics, identifying novel therapeutic targets and biomarkers for diagnosis and treatment. Her systemic disease model challenges traditional views of depression as a brain disorder.
More than a feeling: Could a healthier gut improve mental health?
Researchers from the University of South Australia explore the connection between the gut and brain to decipher their role in mental health and wellbeing. The study found that changes in the gut microbiome can directly affect brain chemistry, suggesting a potential link between gut health and mental illness.
Beyond viruses: Expanding the fight against infectious diseases
The Gladstone Infectious Disease Institute is broadening its research scope to tackle pressing health challenges beyond viruses. Scientists are discovering new ways to combat antibiotic-resistant bacteria and explore the interconnectedness of viruses and bacteria in causing chronic diseases.
Oral bacteria linked to Parkinson’s via the gut-brain axis
Research links oral bacteria to Parkinson's disease via the gut-brain axis, finding Streptococcus mutans produces metabolite imidazole propionate that contributes to disease progression. Targeting the oral-gut microbiome may offer a new therapeutic approach for Parkinson's treatment.
Oral microbes linked to increased risk of pancreatic cancer
Researchers identified 27 species of bacteria and fungi that collectively increase the risk of pancreatic cancer by 3.5 times. The study analyzed saliva samples from 122,000 healthy individuals and found that boosting the mouth's microbiome may protect against cancer.
Special lactic acids reduce antibiotic resistance in infants
Researchers at DTU have discovered a way to combat antibiotic-resistant bacteria by nourishing special bifidobacteria that is naturally occurring in the gut. Special lactic acids produced by bifidobacteria play a key role in keeping antibiotic-resistant bacteria at bay.
Maternal gut microbiome composition may be linked to preterm births
A study published in Cell Host & Microbe found a significant link between the maternal gut microbiome and preterm birth. The researchers identified Clostridium innocuum as a key bacteria species that may contribute to preterm birth by degrading estradiol, a critical hormone during pregnancy.
Can the 'good' bacteria in your mouth act as probiotic cavity fighters?
A UC Berkeley professor and her team have discovered gene clusters in the oral microbiome that produce molecules helping good bacteria stick to teeth, outcompeting acid-producing cavities. The researchers plan to introduce these gene clusters into healthy bacteria to form strong biofilms, reducing cavities.
How stress and social struggles fuel America’s obesity crisis
A new scientific review reveals that stress, hardship, and social challenges reshape a person's gut bacteria and brain performance, making it harder to keep weight off. Social determinants of health play a key role in obesity risk, and addressing these conditions is crucial for long-term solutions.
What gut bacteria like
Researchers have discovered that gut bacteria can recognize diverse chemical signals, including those from nutrients, DNA, and other metabolites. This allows them to detect and respond to nutritional values, suggesting that finding sources of nutrients is a primary function of motility in these bacteria.
Yogurt and hot spring bathing show a promising combination for gut health
Researchers at Kyushu University discovered that combining yogurt intake with hot spring bathing enhances gut microbiota diversity and improves defecation status, suggesting a potential application for preventive medicine. The study found significant improvements in gut health outcomes, particularly among healthy adults.
Scientists find a microbial molecule that restores liver and gut health
Researchers found that a compound produced by Lactobacillus bacteria can reverse liver and gut damage caused by aflatoxin exposure. The molecule, 10-hydroxystearic acid, activated PPARα signaling to repair liver tissue and support gut health.
Bridging Two Frontiers: Mitochondria & Microbiota – Targeting extracellular vesicles 2025 to explore game changing pathways in medicine
Researchers will explore the intersection of mitochondria and microbiota through extracellular vesicles for diagnostics, targeted drug delivery, and regenerative medicine. The conference aims to accelerate scientific progress by building bridges between disciplines.
Disarming a hidden killer: Predicting – and preventing – C. diff before it strikes
Institute for Systems Biology researchers use microbial community-scale metabolic models to simulate C. diff behavior in human gut microbiome samples. They accurately predict colonization states, susceptibility, and response to probiotics, offering a path to prevent C. diff before it starts.
Frontiers Forum Deep Dive series: Microbial map reveals countless hidden connections between our food, health, and planet
Researchers have mapped microbial networks underpinning healthy food systems, highlighting the need for integrated approaches to address climate crisis, antibiotic overuse and pesticide reliance. This work is driving microbiome-based solutions for animal, human and environmental health.
Microbiome breakthrough: Gut bacterium may hold key to future treatments for widespread chronic diseases
A new study has identified a common bacterial strain that produces signaling proteins influencing hormonal balance and affecting weight, bone density and blood sugar levels. The researchers discovered that RORDEP-producing bacteria can vary greatly between individuals and that people with high levels of these bacteria tend to be leaner.
Healthy food systems: Microbial map reveals countless hidden connections between our food, health, and planet
Researchers have mapped the microbiome of agri-food systems, revealing how diverse and balanced microbes keep our food safe, nutritious, and sustainable. The map highlights areas where targeted interventions such as probiotics and biofertilizers can improve food quality and reduce antibiotic use.
Gut microbes: How many molecules influence our body?
Researchers at ETH Zurich and Stanford University quantified the number of molecules produced by gut bacteria that reach the human body daily. This knowledge helps understand how the gut microbiome influences health and behavior.
Japanese industry leaders support Tokyo Microbiota 2025
Four leading Japanese corporations in the health and nutrition sectors have joined forces to advance microbiome science. The event aims to explore recent research and development achievements, engage with industry innovators, and promote practical applications of fundamental research.
Your microbiome, your medicine: Scientists gather in Valencia to redefine the future of health
The 12th World Congress on Targeting Microbiota explores the microbiome's role in diagnostics, therapeutics, and systems biology. Emerging data reveal bidirectional interactions between psychotropic medications and the microbiome, highlighting new approaches to mental health.
Inhaled agricultural dust disrupts gut health
A study by University of California, Riverside researchers found that inhaling agricultural dust can alter the gut microbiome and impair intestinal function, leading to increased 'leaky gut' and associated chronic diseases. The study highlights the need for protective measures for agricultural workers.
Tokyo to host global summit showcasing the nation’s leadership in microbiome medicine & fermentation science
Japan is set to host a global summit on microbiome medicine and fermentation science, featuring pioneering research and collaboration among industry leaders. The event aims to promote personalized nutrition, microbial diagnostics, and next-generation therapeutics.
Prizewinner’s research reveals how immune responses to friendly skin microbiota could pave way for novel vaccination responses
Djenet Bousbaine's research explores how the immune system responds to beneficial skin microbes, triggering wound-healing T cells and robust B cell responses. This phenomenon is observed in humans, non-human primates, and found to be evolutionary conserved.
A global microbiome preservation effort enters its growth phase
A global effort to preserve healthy microbes is now entering an active growth phase, with a team of scientists laying out an ethical framework to ensure equitable collaboration and depositor sovereignty. The Microbiota Vault Initiative aims to safeguard microbial diversity for future generations.
First systematic review finds gut-brain axis impacts treatment outcomes in bipolar patients
A new systematic review reveals a significant connection between the gut microbiome and brain function in bipolar patients, affecting treatment responses. Patients who responded to treatment had distinct gut microbiome profiles similar to healthy individuals.
Salk Institute scientist Deepshika Ramanan named Rita Allen Foundation Scholar
Deepshika Ramanan, a Salk Assistant Professor, has been recognized as a Rita Allen Foundation Scholar for her innovative research on maternal immunity and lactation. She will receive annual grants of up to $110,000 to conduct groundbreaking work in neuroscience, cancer, immunology, and pain.
Multiple sclerosis: Triggers in the gut flora
A study of twins reveals that certain bacteria in the small intestine may trigger MS. Researchers identified two specific bacteria, Lachnoclostridium sp and Eisenbergiella tayi, which are associated with the disease. The findings suggest a new potential therapeutic target for MS treatment.
Baby's microbiome may protect against childhood viral infection
A new study suggests that certain microbiome compositions in babies born vaginally, specifically with a higher amount of pioneer bacteria B. longum, are less likely to be hospitalised for viral lower respiratory tract infections (vLRTI) in the first two years of life.
Study suggests obesity contributes to anxiety and cognitive impairment
Researchers found that obese mice displayed more anxiety-like behaviors and showed different signaling patterns in the hypothalamus, a region involved in regulating metabolism. The study also observed distinct differences in the makeup of gut bacteria in obese mice compared to lean mice.
Using bacteria to improve microbiota resistance to pathogens
Researchers identified seven bacteria with a potential barrier effect against vancomycin-resistant enterococci. The addition of the bacterial mixture reduced the proliferation of pathogenic bacteria in mice, suggesting a promising therapeutic approach.
Gut bacteria and acetate, a great combination for weight loss
A study published in Cell Metabolism finds that a combination of gut bacteria and acetate reduces obesity in mice. The researchers discovered that the specific combination of Bacteroides species and acetate leads to increased fat burning and reduced sugar storage, resulting in weight loss.
A turning point in medicine: phage therapy moves from promise to practice
The international conference will focus on translating phage research into clinical reality, exploring key sessions and major speakers. Companies from various sectors are attending the event, highlighting the growing interest in phage therapy.
New study reveals our skin’s own bacteria can help protect us from the bad effects of sunlight
Researchers discover certain skin bacteria metabolize cis-urocanic acid using enzyme urocanase, fine-tuning immune response to UV radiation. This finding opens the door to microbiome-aware sun protection, where resident microbes are considered in sun protection strategies.
New framework helps estimate sample size for microbiome association studies
A new study provides a method to estimate sample size required for microbiome studies based on effect sizes and analysis methods. For strong associations, around 500 participants were needed to achieve 80% statistical power, while weaker associations may require thousands of samples.