Articles tagged with Human Microbiota
Institute for Systems Biology researchers use microbial community-scale metabolic models to simulate C. diff behavior in human gut microbiome samples. They accurately predict colonization states, susceptibility, and response to probiotics, offering a path to prevent C. diff before it starts.
A new study has identified a common bacterial strain that produces signaling proteins influencing hormonal balance and affecting weight, bone density and blood sugar levels. The researchers discovered that RORDEP-producing bacteria can vary greatly between individuals and that people with high levels of these bacteria tend to be leaner.
Researchers have mapped the microbiome of agri-food systems, revealing how diverse and balanced microbes keep our food safe, nutritious, and sustainable. The map highlights areas where targeted interventions such as probiotics and biofertilizers can improve food quality and reduce antibiotic use.
Researchers have mapped microbial networks underpinning healthy food systems, highlighting the need for integrated approaches to address climate crisis, antibiotic overuse and pesticide reliance. This work is driving microbiome-based solutions for animal, human and environmental health.
Researchers at ETH Zurich and Stanford University quantified the number of molecules produced by gut bacteria that reach the human body daily. This knowledge helps understand how the gut microbiome influences health and behavior.
Four leading Japanese corporations in the health and nutrition sectors have joined forces to advance microbiome science. The event aims to explore recent research and development achievements, engage with industry innovators, and promote practical applications of fundamental research.
The 12th World Congress on Targeting Microbiota explores the microbiome's role in diagnostics, therapeutics, and systems biology. Emerging data reveal bidirectional interactions between psychotropic medications and the microbiome, highlighting new approaches to mental health.
A study by University of California, Riverside researchers found that inhaling agricultural dust can alter the gut microbiome and impair intestinal function, leading to increased 'leaky gut' and associated chronic diseases. The study highlights the need for protective measures for agricultural workers.
Japan is set to host a global summit on microbiome medicine and fermentation science, featuring pioneering research and collaboration among industry leaders. The event aims to promote personalized nutrition, microbial diagnostics, and next-generation therapeutics.
Djenet Bousbaine's research explores how the immune system responds to beneficial skin microbes, triggering wound-healing T cells and robust B cell responses. This phenomenon is observed in humans, non-human primates, and found to be evolutionary conserved.
A global effort to preserve healthy microbes is now entering an active growth phase, with a team of scientists laying out an ethical framework to ensure equitable collaboration and depositor sovereignty. The Microbiota Vault Initiative aims to safeguard microbial diversity for future generations.
A new systematic review reveals a significant connection between the gut microbiome and brain function in bipolar patients, affecting treatment responses. Patients who responded to treatment had distinct gut microbiome profiles similar to healthy individuals.
Deepshika Ramanan, a Salk Assistant Professor, has been recognized as a Rita Allen Foundation Scholar for her innovative research on maternal immunity and lactation. She will receive annual grants of up to $110,000 to conduct groundbreaking work in neuroscience, cancer, immunology, and pain.
A study of twins reveals that certain bacteria in the small intestine may trigger MS. Researchers identified two specific bacteria, Lachnoclostridium sp and Eisenbergiella tayi, which are associated with the disease. The findings suggest a new potential therapeutic target for MS treatment.
A new study suggests that certain microbiome compositions in babies born vaginally, specifically with a higher amount of pioneer bacteria B. longum, are less likely to be hospitalised for viral lower respiratory tract infections (vLRTI) in the first two years of life.
Researchers found that obese mice displayed more anxiety-like behaviors and showed different signaling patterns in the hypothalamus, a region involved in regulating metabolism. The study also observed distinct differences in the makeup of gut bacteria in obese mice compared to lean mice.
Researchers identified seven bacteria with a potential barrier effect against vancomycin-resistant enterococci. The addition of the bacterial mixture reduced the proliferation of pathogenic bacteria in mice, suggesting a promising therapeutic approach.
A study published in Cell Metabolism finds that a combination of gut bacteria and acetate reduces obesity in mice. The researchers discovered that the specific combination of Bacteroides species and acetate leads to increased fat burning and reduced sugar storage, resulting in weight loss.
The international conference will focus on translating phage research into clinical reality, exploring key sessions and major speakers. Companies from various sectors are attending the event, highlighting the growing interest in phage therapy.
Researchers discover certain skin bacteria metabolize cis-urocanic acid using enzyme urocanase, fine-tuning immune response to UV radiation. This finding opens the door to microbiome-aware sun protection, where resident microbes are considered in sun protection strategies.
A new study provides a method to estimate sample size required for microbiome studies based on effect sizes and analysis methods. For strong associations, around 500 participants were needed to achieve 80% statistical power, while weaker associations may require thousands of samples.
The 8th World Congress on Targeting Phage Therapy 2025 will bring together global phage community to address clinical, regulatory, and industrial challenges. The event will feature cutting-edge research, real-world clinical insights, and applications of bacteriophage therapy across medicine, oncology, agriculture, and industry.
The summit will highlight the latest research on coronavirus, plant-based protein, and probiotics, with a focus on their applications in clinical practice. Studies have found that COVID-19 affects the gut microbiome in children, while dietary protein like S100B may promote a healthy microbiome.
A study by Flinders University found that certain bacteria in the throat may indicate greater health vulnerability in older adults. The presence of Staphylococcus aureus was linked to higher mortality rates, even after adjusting for other health factors.
The Blavatnik Awards for Young Scientists in the UK recognize promising scientists under 42 for their work on pressing issues. The three winners are tackling infant mortality, green manufacturing, and predicting long-term climate change. Their prize-winning research will receive £100,000 in unrestricted funds.
Researchers developed a synthetic microbiome therapy using limited strains of gut bacteria to effectively protect against C. difficile infections in mice. The treatment was as effective as traditional fecal transplants and had fewer safety concerns, offering a new alternative for treating this notoriously difficult-to-treat infection.
A new study developed a human microbiota modelling system capable of predicting each person's sensitivity to an emulsifier, such as carboxymethylcellulose (CMC), using a simple stool sample. The model identified a specific metagenomic signature of sensitivity to CMC, allowing for the prediction of individual susceptibility.
Researchers at TUM have developed a new therapeutic approach combining dietary therapy with fecal microbiome transfer to sustain inflammation-free states in Crohn's disease patients. The study found that the gut microbiome changes as a result of dietary therapy contribute to treatment success.
A global research collaboration identified Lactobacillus crispatus as a key protective bacterium in the vaginal microbiome. The study also found significant variations in vaginal microbiomes across human populations, with implications for improved diagnostics and treatments.
A global 'sisterhood' of citizen scientists sheds light on the complex vaginal microbiome, highlighting associations between microbial composition and clinical conditions like preterm birth and urinary tract infections. The study emphasizes the importance of considering whole complexity and continuity in vaginal microbiota composition ...
A new Weizmann Institute study identified all proteins in a stool sample – those from the microbiome, human body, and food – revealing secrets of the intestines and their impact on human disease. The method, dubbed IPHOMED, decodes microbiome activity by showing which proteins come from bacterial strains and amounts.
Research from RIKEN Center for Integrative Medical Sciences found that infant gut bacteria are associated with food sensitivities and allergies, particularly to eggs. The study suggests that probiotic supplements, such as Bifidobacterium, may help prevent food allergies in at-risk infants.
Researchers found that a person's microbiome signature can predict the likelihood of Enterobacteriaceae colonization. Fiber-rich foods support the growth of beneficial Faecalibacterium, which produce short-chain fatty acids protecting against infection.
Researchers discovered a set of genes in Lactiplantibacillus plantarum that enable it to stably attach to host tissue, revolutionizing our understanding of microbiome colonization. This breakthrough could lead to the creation of targeted probiotics and improved gut health.
The winners of the Applied Microbiology International Horizon Awards 2024 have been named, including the One Health Microbiome Center at Penn State and researchers Dr. François Thomas and Dr. Helen Onyeaka.
A recent study published in the journal Microbiome found that lifestyle factors, such as diet and smoking habits, significantly impact the composition of beneficial bacteria in the mouth. The research team analyzed saliva samples from individuals representing different subsistence strategies in Nepal and discovered a correlation betwee...
A team of researchers has identified numerous bacteria with potential therapeutic applications, including those related to respiratory diseases. By analyzing the microbiome of humans and animals, they have discovered genetic blueprints for natural products that could be used to develop new medications.
A new study has identified novel strains of microbes that have adapted to use limited resources in cities, including those found in Hong Kong's subways and skin. These microbes can metabolize manufactured products, posing health risks if they are pathogenic.
Researchers identify two distinct groups of bacteria: the Foundation Guild and Pathobiont Guild, crucial for maintaining human health. The Two Competing Guilds model offers personalized nutrition and targeted therapies to restore balance in the gut microbiome.
Repeated antibiotic use can cause defects in the gut's protective mucus barrier, even months after treatment. This is due to changes in the microbiota or direct effects of antibiotics on the mucus layer. The findings suggest that antibiotics should be used responsibly to prevent long-lasting damage.
Researchers discovered Corynebacterium matruchotii's unique cell division mechanism, enabling dense networks within dental plaque biofilms. This process allows the bacteria to explore their environment and form beneficial interactions.
Researchers have developed a comprehensive database of the 'food microbiome' by sequencing metagenomes from 2,533 foods, identifying 10,899 food-associated microbes. The study shows that these microbes can influence human health and provide insights into how to improve food quality, safety, and authenticity.
The game illustrates how lifestyle choices, such as eating vegetables and drinking alcohol, impact the human microbiome. Researchers developed the game to provide a comprehensive overview of the microbiome in a fun and accessible way.
Researchers engineered human skin bacteria to produce less lactic acid, attracting fewer mosquitoes to mice. The engineered microbes reduced mosquito attraction by up to 64.4% and also prevented bites.
Researchers found that bowel movement frequency is linked to long-term health, with younger people, women, and those with lower BMI tending to have less frequent bowel movements. The study also showed associations between bowel movement frequency and chronic disease risk, mental health history, and gut microbiome composition.
Researchers developed a novel approach to simulate personalized, microbiome-mediated responses to diet using microbial community-scale metabolic modeling. The method predicts individual-specific short-chain fatty acid (SCFA) production rates in response to different dietary, prebiotic, and probiotic inputs.
Researchers at Tufts University have developed a small device that can sample the full inventory of microorganisms in an individual's gastrointestinal tract. The technology uses a soft elastic exterior and microvalves to collect samples, offering improved control over localized sampling in the small intestine.
Researchers found two opportunistic bacteria significantly more abundant after three months of daily use, Fusobacterium nucleatum and Streptococcus anginosus. A decrease in Actinobacteria was also observed, crucial contributors to blood pressure regulation.
A team of researchers created a microfluidic human cervix model that replicates the complex interactions between cervical epithelial cells, mucus production, and microbiome. The Cervix Chip technology offers a new testbed for bacterial vaginosis therapeutics and other treatments, addressing a key women's health gap.
A recent study discovered a unique vaginal microbiome in patients with gynecological cancers, which could serve as a diagnostic biomarker. The researchers found a decrease in beneficial bacteria and an increase in potentially pathogenic microorganisms, leading to promising results for early detection.
African researchers are urging fair collaboration in microbiome studies to explore unique populations and environments, addressing a significant knowledge gap. The proposed framework emphasizes community involvement, capacity building, and multidisciplinary collaboration for sustainable outcomes.
A study has found that multiple species of Gardnerella, commonly linked to pre-term birth and bacterial vaginosis, can exist together in the same vaginal microbiome. This discovery adds to the understanding of Gardnerella's effects on human health and its potential role in pre-term birth.
A study found that individuals taking probiotic supplements showed increased sensitivity to fairness and a greater inclination to reject unequal offers. This was accompanied by changes in gut microbiota composition and levels of dopamine precursors. The findings suggest a potential causal mechanism linking gut bacteria to social behavior.
A study by the University of Cambridge and Fudan University found that children born by C-section are up to 2.6 times more likely to fail their first measles vaccination compared to those born naturally. Two doses of the vaccine are necessary for robust protection against measles.
Research suggests that microbes in the human gut influence social behavior, with certain bacteria offering protection against intestinal problems. The study found specific species of Blautia and Bacteroides uniformis that may benefit people with autism and GI disorders.
Researchers created a new model to study the effects of undernutrition on the microbiome, which can help identify specific microbes that impact development. The model mimics early childhood experiences and shows promise in understanding the underlying causes of stunted growth and other harmful effects of undernutrition.
A study published in Cell reveals a detailed catalogue of bacteria living in cancer metastases, including links to therapy efficacy and tumor cell activity. The research provides new insights into how bacteria interact with cancer cells and their surroundings.
The study found that Streptococcus and Pedobacter bacteria species were present in healthy eyes, while more Acinetobacter species were found in dry eye samples. This knowledge could lead to improved treatments for various eye problems and diseases affecting the gut microbiome.
The fungus C. albicans uses both yeast and hyphae forms to colonize the intestine efficiently when a complex bacterial community is present. The hyphal form produces Candidalysin, which inhibits bacterial metabolism, giving the fungus a competitive advantage.
The American Society for Biochemistry and Molecular Biology's annual meeting features exciting research findings on antibacterial compounds, whooping cough infection, nicotine addiction, and more. Complementary on-site press passes will be issued to a limited number of attendees.