Articles tagged with Human Microbiota
Researchers mapped the normal microbial make-up of healthy humans, shedding light on vital tasks such as immune system support and food digestion. The study reveals a unique personal microbiome for each individual, with over 10,000 species occupying the human ecosystem.
The Forsyth team, led by experts in oral and craniofacial microbiology, contributed to the Human Microbiome Project's definition of normal bacterial makeup. The study found that microbes contribute more genes responsible for human survival than humans themselves, with an estimated 360-times more bacterial genes.
The Human Microbiome Project identified a diverse and abundant microbiota in healthy humans, with varying composition across body sites and individuals. Ethnic/racial background was found to be the strongest association for diversity in the Western human microbiome.
Researchers mapped the normal microbial make-up of healthy humans, identifying over 10,000 species and 8 million unique protein-coding genes contributed by human microbiome.
Researchers have identified over 10,000 microbial species living in humans and found that between 81-99% of genera were present in healthy adults. The study's findings highlight the role of beneficial microorganisms in maintaining health and provide insights into their functions.
A comprehensive census of the microbial make-up of healthy humans identified over 10,000 species of microbes occupying various body sites. The research found unique communities of microbes in every site, with skin hosting the most diverse collection, while teeth and gums had distinct microbiota profiles.
Researchers identified four types of bacterial communities in healthy adults at 10 sites along the digestive tract. They found a core set of metabolic genes present throughout, suggesting common functions needed for bacterial communities living on mucosal surfaces.
The Human Microbiome Project's findings reveal a complex network of microbial diversity, with an estimated 10,000 bacterial species in the human microbiome. The study challenges traditional health concepts by showing that there is not just one way to be healthy, but rather a range of 'just fine' communities.
The Human Microbiome Project Collection provides a comprehensive baseline of the microbial diversity at 18 human body sites, including reference genomes and metagenomic sequences. The studies examine relationships between the microbiome and host health, shedding light on conditions such as Crohn's disease and psoriasis.
Researchers have mapped the normal microbial makeup of healthy humans, revealing that nearly everyone carries pathogens but they cause no disease in healthy individuals. The human microbiome plays a vital role in human health and contributes to human metabolism.
Researchers from Indiana University have conducted the most in-depth genetic analysis of defense systems used by trillions of micro-organisms to fend off viruses. The study identifies 64 known and 86 novel types of CRISPRs, providing a history of past exposures to outside invaders like plasmids and bacteriophages.
A study published in PLOS ONE found that microbial communities on the skin influence attractiveness to mosquitoes. Individuals with lower diversity and higher abundance of bacteria were more attractive to Anopheles gambiae sensu stricto mosquito, which plays a key role in malaria transmission.
Researchers developed a new fluorescent labeling technology to sort the human oral microbiome. The system revealed unexpected interactions between Prevotella and Actinomyces species, suggesting central roles in biofilm production.
Researchers at NYU Langone Medical Center explore how gut bacteria influence cancer risk, suggesting early exposures to H. pylori may protect against gastric cancers later in life. The study also highlights the estrobolome, a framework for understanding estrogen's impact on cancer development.
Scientists present research on healthy microbes, mosquito-borne diseases prevention and E. coli food contamination. Researchers shed light on standing water mosquito breeding in cities and its impact on controlling larval mosquitoes. They also examine the complex relationships between humans and microbes in food production systems.
A study on human bellybutton microbiomes found diverse bacterial communities, similar to those on the skin, but also stable over time and between family members. The research used citizen science to collect and analyze 391 samples, shedding light on human health and environmental interactions.
A new study in Cell Metabolism reveals the microbiome's significant effects on metabolism in mice, highlighting butyrate as a primary energy source for colon cells. Butyrate levels have been linked to dietary and clinical implications, including colorectal cancer prevention.
Dr. Blaser and his team will investigate whether changes in the human microbiome as a result of antibiotic use have fueled the obesity epidemic. The grant will assess the roles of gastric and colonic microbiota related to hormones and metabolism in both humans and mice.
A team of scientists from Mayo Clinic, University of Illinois at Urbana-Champaign, and J. Craig Venter Institute are investigating the relationship between vaginal microbiota and preterm birth. They aim to identify microbial risk predictors for preterm birth using genomic information from the Human Microbiome Project.
A three-year grant from NIH will fund a UChicago-Argonne team developing single-cell confinement technology for cultivating microbes in the human gut microbiome. This project aims to overcome traditional cultivation limitations and target poorly understood sulfur-reducing bacteria associated with ulcerative colitis.
The National Institutes of Health has awarded $42 million to expand eight demonstration projects investigating the link between changes in the human microbiome and health, as part of the Human Microbiome Project. The expanded studies will also support technology development to improve microbiome identification and characterization.
The Human Microbiome Project has launched a centralized database for sequencing microbial genomes, providing a unique resource for future investigations. The HMP has cataloged over 1,400 individual human microbiome projects, enabling researchers to study the interactions between human and microbial cells.
The Baylor College of Medicine team has successfully sequenced 178 microbial reference genomes representative of the human body. These reference genomes will help scientists understand and contextualize the data accumulated over time, providing valuable insights into the complex relationship between humans and their microbiota.
Researchers have published the first genomic collection of human microbes, discovering novel genes and proteins serving key roles in human health and disease. The analysis found nearly twice the amount of microbial diversity as represented by existing public databases.
Recent advances in microbial genomics have enabled researchers to study the human microbiome, revealing its essential role in digestion and immune system development. The Human Microbiome Project aims to optimize the beneficial effects of microbiota for each individual, improving health outcomes.
Researchers at NYU Langone Medical Center have discovered an altered type of microbiome dominated by Gram-negative bacteria in patients with esophagitis and Barrett's esophagus. This finding may provide a new approach to understanding the pathogenesis of reflux-related disorders.
Two NYU Langone researchers will conduct pilot demonstration projects on microbiome and psoriasis and microbiome and esophageal cancer. The studies aim to assess the relationship between the skin or esophageal microbiome and disease progression.
The Human Microbiome Project is expanding its efforts to understand the relationship between the microbiome and human health. The NIH has awarded over $42 million to fund sequencing centers and disease projects, including studies on psoriasis, bacterial vaginosis, obesity, and Crohn's disease.
A global survey of salivary microbes found that the oral microbiome diversity among individuals is similar to that among people from different parts of the world. The study, led by Dr. Mark Stoneking, analyzed bacterial gene sequences from saliva samples from 120 healthy subjects across six geographic areas and compared them with a dat...
A recent study by Cecil Lewis at the University of Oklahoma reveals that ancient microbes can provide insights into modern human health. The researchers analyzed 1,300-year-old feces from Central Mexico and found them to be more geographically structured than modern microbiomes.
The NIH Human Microbiome Project awards funding to develop innovative technologies and computational tools for analyzing microbial communities in the human body. Researchers aim to improve understanding of how microbes interact with health and disease.
Researchers found a common core skin microbiome in healthy individuals, dominated by Proteobacteria species. The study establishes the basis for determining a core microbiome, which may hold the key to novel treatments for skin conditions like acne and atopic dermatitis.
The Human Oral Microbiome Database (HOMD) is a free online compendium that provides detailed biological entries for each species and an extensive catalogue of the thousands of genes expressed by these microbes. The database aims to facilitate research into oral diseases such as tooth decay and periodontal disease.
The Human Oral Microbiome Database provides detailed information on the 600 most common mouth bacteria, their role in oral health and general well-being. The database links genetic data to scientific literature and allows for analysis of microbe genomes.
The Human Microbiome Project aims to understand the interactions between microorganisms and the human body, with potential applications for preventing, diagnosing, and treating diseases. The project will sequence microbial genomes from over 1,000 sources, including healthy volunteers and those with specific diseases.