Articles tagged with Microbiota
A new study from the University of Copenhagen reveals that astronauts experience changes in their gut bacteria shortly after leaving Earth and gravity behind. The researchers found increased protein fermentation, which may contribute to constipation, and suggest potential interventions for future long-duration space missions.
Research at UT MD Anderson Cancer Center has identified biomarkers to identify patients with resectable NSCLC who benefit most from perioperative immunotherapy. The center also found that the composition of donor cord blood may influence CAR NK cell therapy outcomes.
Researchers found that upper and lower surfaces of oak leaves support different microbial communities, with the upper surface hosting stress-tolerant genera and the lower surface favoring sugar-fermenting taxa and insect-associated bacteria. The two sides show striking seasonal divergence in terms of diversity and abundance.
Researchers at Boston Children's Hospital found that fecal transplants from healthy donors reduced peanut allergy symptoms in some patients. The study suggests that the right bacteria can help restore tolerance to food through bile acid metabolites. Increased levels of immune regulatory cells also protected against allergic reactions.
A study found that reshaping the gut microbiome with antibiotics can significantly reduce liver clearance and double chemotherapy delivery to tumors. This approach has potential as a strategy to enhance nanoparticle-based cancer drugs.
Hepatic encephalopathy recurrence can be reduced through education on precipitants correction and pharmacotherapy with lactulose and rifaximin. Nutritional support with protein-rich diets improves QOL and reduces episodes.
Researchers at UC Davis identified a naturally occurring metabolite, 10-hydroxystearic acid (10-HSA), that repairs gut damage caused by HIV infection. Combining 10-HSA with standard antiretroviral therapy improved viral suppression and helped rebuild gut immune defenses in animal models of AIDS.
A novel treatment approach combining phage therapy and fecal microbiota transplantation has shown promise in treating recurring urinary tract infections. The study, published in Nature Microbiology, found that the treatment reduced UTI episodes and improved quality of life for patients.
A new liquid-based platform called 'floatony' can form and maintain complex three-dimensional microbial structures while preserving molecular diffusion, spatial structures, and cell mobility. This approach could offer new ways to study gut microbiota, biofilms, and other spatially organized microbial communities.
Researchers at Duke University have developed a method to systematically develop novel probiotic and prebiotic combinations to maintain gut health and treat gastrointestinal diseases. The approach uses machine learning and automation to explore complex interactions between microbes, nutritional sources, and the environment.
Researchers develop synthetic microbial communities to degrade persistent herbicides, improving degradation rates by 1.5-3 times compared to individual strains or natural attenuation. The approach promotes more complete mineralization of pollutants and resilience in complex soil environments.
Researchers are studying foul-smelling substances to understand what attracts the New World screwworm, a flesh-eating parasite, to its favorite meal - open wounds. The goal is to develop better lures for trapping this serious threat to the livestock industry.
A UMaine-led research team has been awarded the inaugural DOE Genesis Mission to develop AI-powered models that simulate the impact of microbes on underground chemical reactions. The project aims to improve predictions in groundwater management, environmental remediation, and energy infrastructure planning.
A randomized clinical trial found that ingesting fecal microbes from healthy donors improved sleep efficiency and reduced wake after sleep onset in participants with chronic insomnia. Sleep quality scores also showed significant improvement over two months.
A new study argues that the microbiome-gut-brain axis has been predominantly studied in wealthy, industrialised nations, limiting scientific discovery. The authors call for greater international collaboration and investment in research infrastructure to uncover universal biological principles that can improve mental health worldwide.
Researchers at Texas A&M University have found a way to intervene early in traumatic brain injuries using a natural, gut-derived chemical that prevents post-traumatic epilepsy from taking root. The treatment reduced brain inflammation, improved memory and mood, protected brain cells, made seizures both rarer and harder to trigger.
A six-year study on drought's impact on soil microbial communities found decreased biodiversity and shifted ecological configurations. This decline affects nutrient cycling processes and broader ecosystem health.
A study by UNIFESP found that chronic xanthan gum consumption causes colon inflammation, alters gut microbiota, and leads to intestinal barrier integrity loss in rats. This supports previous observations of necrotizing enterocolitis in premature infants linked to xanthan gum use.
A new study published in Biochar shows that combining green manure with biochar can improve soil quality, support maize yield, and reduce dependence on nitrogen fertilizer. The research found that soil microbial diversity emerged as a central driver of improved soil quality.
The gut microbiome is recognized as a key driver of tumor initiation and progression, with microbial dysbiosis fueling malignancy or enhancing anti-tumor immunity. Microbiome science and cancer biology are converging to develop new strategies for prevention, diagnosis, and therapy.
Researchers at UT Health San Antonio found a link between the bacterium Faecalibacterium prausnitzii and systemic lupus erythematosus. Supplementation with this bacteria reduced markers of the disease in animal models, showing promise for treatment.
A study published in Frontiers in Cellular and Infection Microbiology found that healthy infant gut microbiomes are linked to reduced risk of malaria. Babies with beneficial microbes like Bifidobacterium were less likely to develop the disease. However, further research is needed to confirm this association.
Researchers found that over-the-counter probiotics contain only 36 unique species of bacteria, with most common species being forms of Lactobacillus. The analysis suggests a lack of consistency in the combination of species used to support gut health and vaginal health claims.
Researchers from Institute of Science Tokyo found that postbiotic foods can improve gum health in adults with mild gingivitis, reducing gum bleeding and inflammation. The study suggests a simple way to support oral health without altering oral care habits.
A pilot clinical trial found that adding probiotics to standard care reduced depressive and anxiety symptoms in older adults with moderate depression. However, probiotics did not confer clear additional gains in quality of life compared to a placebo.
Researchers found that areas with more vegetation in Taipei's metropolitan area had higher microbial richness and diversity. The Green View Index measures visible greenery from a pedestrian's perspective and correlates strongly with microbial richness.
Jacques Ravel has been recognized for his foundational contributions to understanding the human vaginal microbiome, its links to pregnancy outcomes and susceptibility to infection. His work also laid the groundwork for live biotherapeutics designed to shape the vaginal microbiome in ways that could improve pregnancy outcomes.
Researchers found that cohabiting individuals shared significantly more oral and gut strains than those living in different households. On average, cohabitors shared 19% of their gut microbiome and 26% of their oral microbiome strains with each other.
A study of 60 pregnant women found associations between maternal factors and microbiota-derived extracellular vesicle profiles in amniotic fluid. Maternal overweight and obesity were linked to lower proportions of certain bacterial groups.
Researchers found that eliminating sugar from a low-fat diet can lead to impaired glucose control, insulin resistance, and gut microbial imbalance. Balanced dietary carbohydrates are essential for supporting gut and immune homeostasis.
A study published in Cell Host & Microbe suggests that GLP-1 analogs may alleviate depression in mice by modulating the gut microbiome. The researchers found that a specific microbe strain, Lactobacillus delbrueckii, played a key role in this process.
Researchers found that people living in areas with more vegetation had a wider microbial variety in their noses, correlating with better mental health scores. Time spent outside was also associated with a healthy nasal microbiome and lower depressive scores.
Researchers developed a new method to raise germ-free zebrafish using gamma irradiation, enabling long-term studies of host-microbe interactions. This approach revealed significant differences between germ-free and intact zebrafish, suggesting conserved roles for microbiomes in immunity and metabolism across species.
Researchers investigated the interplay between host and gut microbiota in selenium metabolism, finding that gut microbiota transform selenium into metabolites influencing utilization, detoxification, and excretion. The study also revealed that Se intake affects bacterial diversity and that gut microbes produce unique selenometabolites.
A study by Harvard T.H. Chan School of Public Health found that gut microbiome alterations persist even after adenoma removal, increasing the risk of colorectal cancer. The researchers discovered that diet and physical activity were closely tied to CRC-associated gut microbes, suggesting lifestyle habits may contribute to sustained risk.
A study published in PLOS One analyzed microbial communities in well-preserved and degraded bones from medieval cemeteries in Norway. The researchers found distinct microbial communities associated with different levels of degradation, suggesting that microbes play a role in bone preservation and decay.
A new screening tool tests for microbial metabolites in urine to identify children at risk for autism, with 90% sensitivity and 100% specificity. The test may guide more targeted interventions, including approaches to restore a healthy gut microbiome.
Researchers found that the gut responds to protein deficiency by activating a fast neural circuit and a slower hormonal signal, which selectively changes dietary priorities. The study reveals a previously unknown gut-brain signaling system that rapidly alters feeding behavior in animals.
A Tulane University study found that long-term antiretroviral treatments did not fully restore key immune functions to protect and repair the gut lining in nonhuman primates with SIV. The researchers discovered that diet-derived compounds from vegetables like broccoli and cabbage may support immune activity involved in gut repair.
Researchers found that aerobic exercise counteracted oxidative stress and inflammation caused by nanoplastics in female zebrafish. Exercise also improved neuroendocrine health by altering gut microbe balances.
A new study found that lobster eggs host surprisingly diverse microbiomes that change as the embryos develop but remain stable under conditions simulating future environmental conditions. The findings challenge decades of assumptions about disease risks in the American lobster fishery.
Researchers identified functional differences in Segatella strains from different regions of the world. Genomes of Segatella copri with OxyR showed a hundred to thousand times higher oxygen tolerance than those without, suggesting horizontal gene transfer occurred several thousand years ago.
Researchers tracked six NCAA Division I football players over a season and found that non-concussive head impacts correlated with changes to the gut microbiome. The study suggests that even sub-symptomatic head impacts might affect the gut microbiome, both in the immediate aftermath of injury and over a longer time course.
A new study finds that pregnant women with low levels of a specific fatty acid molecule are more likely to have children with childhood asthma. The researchers also found that children of these mothers are more prone to respiratory infections and altered lung microbiomes.
A study reveals that caesarean delivery alters microbial colonisation in the first days of life, with distinct effects on male and female mice. Males born by caesarean section develop increased susceptibility to colitis in adulthood, while females do not. This difference is linked to changes in gut microbiota and barrier function.
Researchers found that microbes actively adjust their behavior to minimize competition and conflict when living together, leading to more efficient coexistence. This discovery provides insights into how diverse microbial communities assemble and persist despite intense competition.
The Targeting Phage Therapy 2026 Congress will bring together experts to address clinical, regulatory, industrial, and hospital infrastructure requirements for phage therapy. The congress aims to move phage therapy from promising science to accessible, validated, and deployable medicine.
Researchers discovered a new immune tolerance mechanism that relies on blocking Signal Two coupling, rather than expanding it. This finding holds promise for developing new therapies against inflammatory bowel disease and other autoimmune conditions.
Researchers found that restoring a young microbiome can reverse features of aging in the liver, including inflammation and DNA damage. The study suggests that a healthy gut microbiome plays a key role in preventing liver cancer.
Researchers found distinct gut microbiome characteristics that predicted treatment response to the low FODMAP diet and rifaximin. Patients who responded to these treatments had different microbial signatures, with increases in diversity for those on the low FODMAP diet and resilience against antibiotics for those on rifaximin.
A recent study found that antibiotic-resistant bacteria are present in the gut microbiomes of American black bears in eastern North Carolina. The researchers also discovered that these pathogens can be dispersed through bear feces, making the bears a potential indicator species for environmental changes.
Researchers found that connected natural habitats help maintain beneficial skin microbes that inhibit deadly fungal pathogens in tropical amphibians. Habitat fragmentation weakens these microbial defenses, leading to increased pathogen infection levels.
Researchers have developed a new tool called Microbial Interaction and Niche Determination (MIND) that accurately predicts how microbes compete within complex communities. By analyzing nutrient preferences and energy allocation, MIND helps beneficial organisms outcompete dangerous pathogens. This approach has the potential to accelerat...
Researchers found that sleep deprivation alters the composition of gut microbiota, leading to worse cancer progression and reduced effectiveness of chemotherapy. The study highlights the importance of maintaining a healthy microbiome through good sleep and diet.
A new study from the University of East Anglia found that living with friends may alter your gut bacteria, with social closeness driving the exchange of anaerobic microbes. The research suggests that daily interactions at home, such as hugging and sharing food prep spaces, may encourage the transfer of beneficial gut bacteria.
A study found that epigenetic changes present at birth can impact an infant's gut microbiome development during their first year. The researchers also identified specific epigenetic changes and gut microbes associated with signs of autism spectrum disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD).
Researchers at DTU have developed a new method to identify bacteria capable of producing vitamin B2 in soya drinks. A bacterium from bumblebee guts was found to thrive in plant-based dairy alternatives and produce the nutrient in high quantities.
A study led by UNICAMP researchers found that decreased bacteria in the large intestine affects nutrient absorption, particularly in older adults. The research showed a dual function of a previously thought mucus-secreting cell, which absorbs nutrients and regulates its abundance with gut microbiota signals.
The tumor microbiota is now considered a crucial component of the tumor microenvironment, influencing cancer development and modulating immunotherapy effectiveness. Researchers have identified ways microbes can remodel tumors' microenvironments, directly interacting with tumor tissue and immune cells.
A long-term public study found that phytochemicals from oregano and rosemary supported favorable gut health and growth performance in weaned pigs, preserving microbial diversity to improve nutrient utilization. The natural agents outperformed antibiotic growth promoters in terms of final body weight and gain-to-feed ratio.