Articles tagged with Microbiota
Scientists found that breathing dusty air from the Salton Sea can alter the lung microbiome and trigger immune responses in mice. The study suggests that chronic exposure to such dust could have significant health effects, including asthma.
Researchers found that voluntary running exercise mitigates cafeteria diet-induced behavioral changes via hormonal and microbial pathways. The study revealed specific metabolites, such as anserine and indole-3-carboxylate, were decreased by the cafeteria diet but partially restored by exercise.
The winners of the Applied Microbiology International Horizon Awards 2025 have been recognized for their groundbreaking contributions to global challenges through applied microbiology. The awards celebrate excellence across various domains, including drug discovery and sustainable agriculture.
A healthy microbiome promotes overall well-being, influencing areas like cognition, mood, immunity, and disease susceptibility. By incorporating proven dietary interventions, regular exercise, stress reduction, and adequate sleep, individuals can harness their microbiome for optimal health.
Researchers discovered that non-hibernating pikas alter their gut microbiota to increase urea nitrogen salvaging, maintaining protein homeostasis during winter. This adaptation helps the animals cope with the scarcity of dietary protein during the cold season.
Researchers analyzed feces samples from 11 herbivore species in Namibia's Etosha National Park to understand how environmental factors shape their gut microbiomes. The study found five types of bacteria serving as environmental indicators, which could help monitor ecosystem changes and animal adaptation.
Dr. Amin's transformative insights reshape international understanding of depression genetics, identifying novel therapeutic targets and biomarkers for diagnosis and treatment. Her systemic disease model challenges traditional views of depression as a brain disorder.
A recent study found that paeoniflorin treatment corrected imbalances in gut microbiota and key metabolites associated with brain function in a rat model of chronic stress. This corrected the depressive behaviors in stressed rats, which were then transferred to other rats through the shared gut microbiota-metabolite axis.
Researchers from the University of South Australia explore the connection between the gut and brain to decipher their role in mental health and wellbeing. The study found that changes in the gut microbiome can directly affect brain chemistry, suggesting a potential link between gut health and mental illness.
A study on C. elegans reveals that dissolved biochar affects nematode growth and physiology, with lower doses promoting development and higher doses disrupting normal functions. The findings highlight the need for careful dosing and oversight when deploying biochar in agricultural systems.
Researchers discovered a new enzyme produced by Bacteroides fragilis that activates pain signaling. The enzyme is targeted with nanoparticles to develop treatments for gut pain in inflammatory bowel disease and irritable bowel syndrome. The studies aim to restore balance between good and bad bacteria to reduce symptoms.
The 2-day conference focuses on bridging the fields of mitochondrial biology, microbiome research, and extracellular vesicle science to advance translational innovation. Experts will discuss EVs as core messengers in intercellular communication and their potential therapeutic applications.
Research reveals that Bifidobacterium breve in pregnant mothers regulates the placenta's hormone production, reducing complications and improving fetal growth. The study opens up a new approach to assessing pregnancy health through gut microbiome analysis.
A new study by Boston University researchers examines the impact of urban environmental stressors on tree growth and ecosystem services. The study found that urbanization disrupts the tree microbiome, leading to a loss of symbiotic relationships and an accumulation of pathogens, which can have negative effects on human well-being.
The International Society of Microbiota and RIKEN will host the prestigious Innovation Awards Gala to celebrate microbiota-driven discoveries. Nominations for the awards close on October 7, 2025, and recognize scientific excellence and translational breakthroughs in microbiota medicine.
A University of Hawaii study reveals how gut microbes interact with human genes, shaping disease risk, aging, and future medical treatments. The review highlights the potential for personalized medicine and precision health strategies tailored to each individual's unique microbial and epigenetic makeup.
The University of California - Riverside is receiving a $2 million grant to investigate how gut microbes interact with their human hosts to influence health. The research aims to create next-generation probiotics that strengthen the gut microbiome, improve vaccine effectiveness, and prevent infections.
Researchers developed an engineered strain of gut-homing bacteria that induces mature tertiary lymphoid structures, associated with improved survival and stronger treatment responses. The therapy also restored healthy gut microbiota and showed excellent biocompatibility.
Research links oral bacteria to Parkinson's disease via the gut-brain axis, finding Streptococcus mutans produces metabolite imidazole propionate that contributes to disease progression. Targeting the oral-gut microbiome may offer a new therapeutic approach for Parkinson's treatment.
A cohort study reveals oral bacteria and fungi as significant risk factors for pancreatic cancer development. The findings suggest that oral microbiota may serve as biomarkers to identify individuals at high risk of pancreatic cancer, potentially contributing to personalized prevention strategies.
Researchers at DTU have discovered a way to combat antibiotic-resistant bacteria by nourishing special bifidobacteria that is naturally occurring in the gut. Special lactic acids produced by bifidobacteria play a key role in keeping antibiotic-resistant bacteria at bay.
Researchers found genetic peptides called alpha-defensins that shape gut bacteria, producing healthier microbiomes and reducing insulin resistance. This discovery suggests personalized treatments can be tailored to individual genes, offering new hope for addressing chronic diseases like obesity and diabetes.
A study published in Cell Host & Microbe found a significant link between the maternal gut microbiome and preterm birth. The researchers identified Clostridium innocuum as a key bacteria species that may contribute to preterm birth by degrading estradiol, a critical hormone during pregnancy.
Researchers found that children with stable gut microbiomes tend to have better growth outcomes. The study created the first-ever pediatric undernutrition microbial genome catalog, which can predict and prevent malnutrition. This discovery opens the door to new diagnostics and therapeutics for addressing global child stunting issues.
A new scientific review reveals that stress, hardship, and social challenges reshape a person's gut bacteria and brain performance, making it harder to keep weight off. Social determinants of health play a key role in obesity risk, and addressing these conditions is crucial for long-term solutions.
Researchers found a unique microbial signature in colorectal cancer samples that can accurately distinguish them from other types of cancer. This discovery has the potential to improve diagnosis and treatment outcomes for patients with colorectal cancer.
A clinical trial led by Tohoku University has found that lubiprostone can prevent the decline of renal function in patients with chronic kidney disease. The study evaluated the effects of lubiprostone on kidney function and found that it improves mitochondrial function, which exerts a renoprotective effect.
Researchers have discovered that gut bacteria can recognize diverse chemical signals, including those from nutrients, DNA, and other metabolites. This allows them to detect and respond to nutritional values, suggesting that finding sources of nutrients is a primary function of motility in these bacteria.
A team of microbiologists has mapped the multitude of microbes present in mine water, influencing its chemistry and impact on geothermal energy capture. Understanding microbial activity is crucial for designing efficient and resilient geothermal systems.
Researchers at University of California San Diego School of Medicine found that chronic alcohol use impairs gut bacterial regulation. This allows bacteria to migrate to the liver, worsening ALD. Targeting this mechanism with existing drugs may provide a new approach to minimizing liver damage from alcohol use.
Researchers created comprehensive catalogue of human gut microbiota subspecies and developed model predicting colorectal cancer presence from stool samples. The method detected 90% of cancer cases, outperforming current non-invasive detection methods.
Researchers discovered that smoking produces metabolites that encourage mouth bacteria to grow in the large intestines, triggering an immune response. These bacteria, specifically Streptococcus mitis, help reduce inflammation in ulcerative colitis by triggering a specific immune response.
Researchers found that a molecule produced by gut bacteria can cause inflammation, scarring and fibrosis in the kidneys, a major complication of diabetes. Corisin, a small peptide, attaches to albumin in the blood and targets the delicate kidney structures, accelerating aging and cell death.
Researchers at Kyushu University discovered that combining yogurt intake with hot spring bathing enhances gut microbiota diversity and improves defecation status, suggesting a potential application for preventive medicine. The study found significant improvements in gut health outcomes, particularly among healthy adults.
A recent study reveals that foliar fungicides can alter the composition of beneficial fungi in corn leaves, highlighting the need to reassess crop management strategies. The research also suggests that sustainable practices promoting beneficial microbes could enhance crop resilience and yield.
Researchers found a connection between high TMAO levels and faster rates of aneurysm expansion, as well as greater risk for needing surgery. Targeting TMAO levels may help prevent and treat aneurysmal disease beyond surgery.
A new study published in Molecular Nutrition and Food Research found that red meat consumption causes an imbalance of bacteria in the intestinal microbiota, leading to exacerbated colonic inflammation. The diets resulted in a decrease in beneficial bacterial strains and an increase in pro-inflammatory cells.
Researchers discovered a multi-faceted mechanism behind ASD, revealing the gut microbiota and host immune system's influence on disease progression. Precision-selected probiotics restored metabolic balance, reduced neuroinflammation, and ameliorated behavioral abnormalities in ASD mouse models.
Researchers at University of California San Diego have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from metastatic colorectal cancer. The finding has potential clinical applications, including early cancer detection and monitoring of high-risk patients.
A new study has discovered that the microbial signature of tiny planktonic crustaceans, called copepods, reflects ocean currents and environmental gradients more accurately than freely living microbes. This finding suggests that copepod-associated microbes could serve as valuable bioindicators for detecting shifts in marine ecosystems.
Researchers will explore the intersection of mitochondria and microbiota through extracellular vesicles for diagnostics, targeted drug delivery, and regenerative medicine. The conference aims to accelerate scientific progress by building bridges between disciplines.
Researchers found that children unexposed to HIV had higher taxonomic turnover in their oral microbiomes, indicating less adaptability to environmental changes. Children living with HIV had more stable oral microbiomes and higher frequencies of cavity-causing bacteria.
Institute for Systems Biology researchers use microbial community-scale metabolic models to simulate C. diff behavior in human gut microbiome samples. They accurately predict colonization states, susceptibility, and response to probiotics, offering a path to prevent C. diff before it starts.
A new study uses Association Rule Mining to identify complex microbial relationships in the gut microbiome, revealing key beneficial microbes that contribute to gut homeostasis. The research also demonstrates how ARM can enhance disease classification accuracy for conditions like IBD, CRC, T2D, and IGT.
Researchers have identified 48 previously unknown bacterial species in the indri's microbiome, which is largely established through transmission between members of the same social group. This finding has significant implications for preserving the species' habitat and preventing extinction.
Research suggests that consuming high levels of sucralose can make cancer treatment less effective by disrupting the gut microbiome and altering T cell function. However, adding arginine or citrulline supplements to the diet may restore immunotherapy effectiveness in patients with melanoma and non-small cell lung cancer.
Researchers have mapped the microbiome of agri-food systems, revealing how diverse and balanced microbes keep our food safe, nutritious, and sustainable. The map highlights areas where targeted interventions such as probiotics and biofertilizers can improve food quality and reduce antibiotic use.
A new study has identified a common bacterial strain that produces signaling proteins influencing hormonal balance and affecting weight, bone density and blood sugar levels. The researchers discovered that RORDEP-producing bacteria can vary greatly between individuals and that people with high levels of these bacteria tend to be leaner.
Researchers have mapped microbial networks underpinning healthy food systems, highlighting the need for integrated approaches to address climate crisis, antibiotic overuse and pesticide reliance. This work is driving microbiome-based solutions for animal, human and environmental health.
A new study found a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia. Individuals with long COVID face significantly higher rates of these disorders, alongside worse mental health and quality of life.
A low FODMAP diet has been shown to improve colonic barrier function and reduce mast cell activation in patients with IBS-D. The study found that the diet reduced symptoms of diarrhea and abdominal pain, and improved intestinal permeability.
Researchers at ETH Zurich and Stanford University quantified the number of molecules produced by gut bacteria that reach the human body daily. This knowledge helps understand how the gut microbiome influences health and behavior.
Four leading Japanese corporations in the health and nutrition sectors have joined forces to advance microbiome science. The event aims to explore recent research and development achievements, engage with industry innovators, and promote practical applications of fundamental research.
A new study reveals that the human gut microbiota can pinpoint an individual's city of residence with high accuracy, strongly linked to each city's characteristic diet. The researchers identified unique microbial signatures and interaction networks between cities in China, shedding light on how local environments shape our inner biology.
The 12th World Congress on Targeting Microbiota explores the microbiome's role in diagnostics, therapeutics, and systems biology. Emerging data reveal bidirectional interactions between psychotropic medications and the microbiome, highlighting new approaches to mental health.
A study by University of California, Riverside researchers found that inhaling agricultural dust can alter the gut microbiome and impair intestinal function, leading to increased 'leaky gut' and associated chronic diseases. The study highlights the need for protective measures for agricultural workers.
The study reveals diverse microbial profiles within different tumor types, with notable diversity in species composition and spatial localization. Functional effects of intratumoral microbiota on the tumor microenvironment range from immunostimulatory to protumor.
The study found that younger men preferred a fish-centered diet, while older women leaned toward plant-based foods. Dietary diversity increased with age for both men and women, suggesting a shift in dietary preferences over time.
Researchers found that changes in pH levels result in three distinct metabolic states of the community, driven by indigenous biomass activity and nutrient availability. The simple model predicts the activity with just two parameters, offering insights into how soil microbiomes adapt to climate change.
A new study found that consuming pistachios every night for 12 weeks altered bacteria in the gut of adults with prediabetes, increasing beneficial short-chain fatty acids like butyrate. The changes may offer long-term health benefits, potentially slowing Type 2 diabetes development or reducing inflammation.