The University of Hong Kong's Faculty of Arts has launched a pioneering postdoctoral fellowship project to recruit global experts in art conservation, with the goal of advancing cultural and scientific excellence. The fellowship will benefit both HKMoA and HKU, enabling the advancement of collection research and exhibitions.
Researchers from HKUMed identified ACACA and LSS as key factors in lipid metabolism that fuel gastric cancer growth. Targeting these vulnerabilities with cholesterol inhibitors killed cancer cells 6.3-fold, opening new avenues for personalized therapies.
The journal prioritizes research on emerging contaminants, water-carbon-nutrient interplay, and advanced modeling technologies to inform policy and optimize multi-objective management strategies. The new leadership aims to steer the field toward a more sustainable and resilient future for our planet's essential water systems.
A new study by University of Texas M.D. Anderson Cancer Center researchers identified CD40 overexpression as a potential biomarker associated with improved overall survival in angioimmunoblastic T cell lymphoma (AITL). This discovery could lead to therapeutic strategies to improve outcomes for this challenging disease.
Researchers mapped accessible routes to 59 surviving pillboxes along the Gin Drinker's Line in the New Territories, providing guides for visiting British and Japanese military sites. The study highlights the importance of these structures as a unique part of Hong Kong's WWII history and potential tourism assets.
HKU Professor Max Shen has been elected as an International Member of the Chinese Academy of Engineering in recognition of his contributions to artificial intelligence and supply chain optimization. He is advancing AI and supply chain technologies through collaboration with industry, academia, and research institutions.
Researchers from HKU identified six distinct tectonic regimes on terrestrial planets, including a novel 'Episodic-Squishy Lid' regime. This discovery provides clues to the origin of Earth's plate tectonics and offers a robust theoretical framework for deciphering Venus' enigmatic geological features.
Researchers engineered a single-layer color-tunable QLEDs technology where color emission is dynamically tunable through voltage modulation, enabling precise control over color transitions. The innovation achieved a record-breaking 5% external quantum efficiency and delivers three pivotal advantages—enhanced color gamut, simplified man...
A cross-disciplinary research team at HKU successfully applied NIR-II fluorescence video imaging during esophagectomy to reduce anastomotic leakage rate. The technique enables precise guidance for resection and reconstruction by delineating well-perfused and poorly perfused regions of the gastric conduit.
Researchers propose AI-based surrogate brain framework that integrates forward modeling, inverse problem solving, and evaluation to build next-generation data-driven models. The framework enables applications such as predicting future whole-brain activity, performing dynamical systems analysis, and guiding neurostimulation strategies.
Patients with lower-risk myelodysplastic syndromes experienced strong responses with fewer side effects when treated with a five-day azacitidine compared to shorter durations. The five-day regimen offered the best balance of safety and efficacy, demonstrating improved event-free survival and overall survival.
A joint research team from DGIST and Caltech developed a highly efficient photocatalyst that converts carbon dioxide into methane using sunlight. The new structure improves light energy usage, allowing for a fivefold increase in performance compared to ordinary conditions.
This review systematically outlines deubiquitinases' roles in various liver diseases, including metabolic dysfunction-associated steatotic liver disease, liver fibrosis, viral hepatitis, and hepatocellular carcinoma. It highlights their potential as therapeutic targets and emerging technologies for targeting DUBs.
The University of Hong Kong (HKU) has established the James M. and Cathleen D. Stone Center on Socio-Economic Inequality in Asia, a leading research hub addressing wealth inequality in Asia. The center aims to develop evidence-based solutions to inform public policy and discourse.
The TRANSCEND FL trial demonstrates the effectiveness of lisocabtagene maraleucel in achieving durable remissions and favorable safety profiles in patients with relapsed or refractory follicular lymphoma. The therapy produced a 97% overall response rate, with most patients remaining in remission after three years.
A new computational tool has discovered a previously unknown protein pathway that triggers the death of blood cancer cells when blocked. This finding could lead to new treatments and improved survival rates for patients with aggressive acute myeloid leukaemia (AML).
Researchers developed a new formulation for neutral triple gauge couplings, ensuring compatibility with the Standard Model Effective Field Theory. They estimated that future electron-positron colliders can probe these effects, outperforming the LHC and a future 100-TeV proton-proton collider
Research reveals that Methanogenic archaea, particularly M. smithii, play a crucial role in postnatal growth retardation by depleting β-hydroxybutyrate levels and inducing liver inflammation. Transplanting fecal microbiome from PGR piglets to mice confirms the same phenotypes.
The Battery Large Model system revolutionizes battery design, manufacturing, operation, and recycling through AI-simulation synergy. It provides a novel technological path for the industry's intelligent upgrade, enabling autonomous design scheme generation, accurate performance prediction, and intelligent defect detection.
Researchers discovered that locusts regurgitate to repel ant attacks, and the mixture of diethyl glutarate, 3-methylindole, and 2-(formylamino)benzoic acid stimulates ant gustation, leading to aversion
A new study by researchers at Karolinska Institutet found that lower doses of approved immunotherapy drugs can give better results against tumours, while reducing side effects. The regimen with the lower dose of ipilimumab was more effective, with a higher proportion of patients responding to treatment and longer overall survival.
Research finds that standard road crossing intervals are too short for older adults with limited mobility, resulting in a need for slower crossings. The study analyzed walking speeds of 1,110 adults aged 65 and over and found that just 1.5% can cross the road within the typical time allowed by pedestrian signals.
Experts discuss GLP-1 drug efficacy in treating obesity and its associated health issues. Key findings include the neurobehavioral links between mental health and obesity, as well as policy implications for access to these treatments.
A new study presented at ASH 2025 suggests that a virtual program focusing on diet and exercise can help reduce the severity of side effects associated with lymphoma treatment. The program, LIFE-L, showed significant improvements in symptoms such as anxiety, depression, pain, fatigue, and constipation among participants.
In a study published in the Journal of Experimental Biology, researchers from Kobe University found that hawkmoth larvae and pupae produce defensive sounds when stimulated. These sounds are released through respiratory openings and resemble snake warning signals, potentially helping the insects evade predators.
A new study found that a chemo-free combination treatment outperformed targeted therapy and chemotherapy in patients with Ph+ acute lymphoblastic leukemia, achieving higher rates of event-free survival and complete remission. Researchers recommend this approach as the new standard of care for this patient group.
The azacitidine-venetoclax combination significantly improves event-free survival and overall response rates compared to intensive chemotherapy. Patients in the aza-ven arm also experience lower symptom burdens, reduced depression, and improved quality of life.
A new study shows that adding epcoritamab to standard second-line therapy significantly improves follicular lymphoma outcomes, including a nearly 80% reduction in risk of death or disease progression. The treatment was also found to be effective for patients who received it on an outpatient basis.
Pirtobrutinib, a non-covalent Bruton tyrosine kinase (BTK) inhibitor, met its primary endpoint in terms of overall response rate compared to covalent BTK inhibitor ibrutinib. The study suggests pirtobrutinib shows promise as initial BTK inhibitor therapy for patients with CLL and SLL.