Researchers create powerful computational tools, sCCIgen and QuadST, to map how cells communicate in diseases like Alzheimer's and cancer. These tools provide a controlled environment to test methods for detecting cell communication, enabling the discovery of new mechanisms and therapies.
Engineered metasurfaces can focus and control light to trigger responses in specific cells, enabling precise, wireless stimulation. This breakthrough lays the foundation for next-gen bioelectronic implants with targeted cell activation or cancer therapy.
A protein called U2AF1, released by macrophages, helps grow new blood vessels in the heart after a myocardial infarction. U2AF1 regulates alternative splicing of Yap1, enhancing endothelial cell migration and tube formation.
Compulsive behaviours are common across many mental health conditions, where people repeat actions despite negative consequences. New research in rats suggests that triggering inflammation in the striatum may shift behaviour toward more deliberate decision-making, rather than habit.
Benizake salmon farming is expanding in Namie Town, Fukushima, with the help of Japan's Subsidy for Business Location program. The project aims to revitalize commercial activity and create employment opportunities for affected residents after the 2011 Great East Japan Earthquake and Tsunami.
The new program focuses on advancing foundational research in AI, including innovation in language models and algorithmic efficiency. Google will support research grants, scholarships for students, and educational initiatives at the TAU Center.
A new study presents a refined approach to designing ultra-dense LEO satellite constellations tailored for satellite-based computing networks. The proposed constellation model uses an inclined-orbit configuration, which allows for flexible adjustment of orbital parameters to better serve middle–low latitude regions.
Researchers from RIKEN and their international collaborators used deep learning techniques to analyze unexamined nuclear emulsion data and identified a new double-Lambda hypernucleus. This is the world's first AI-assisted observation of such an exotic nucleus, providing new insight into neutron star cores.
A new hybrid anode technology has been developed that delivers higher energy storage while reducing thermal runaway and explosion risks. The 'magneto-conversion' strategy applies an external magnetic field to ferromagnetic manganese ferrite conversion-type anodes, promoting uniform lithium ion transport and preventing dendrite formation.
A new study reveals that recent changes in air pollution are not the main reason for Earth's increasing energy imbalance. Cloud changes, driven by surface warming and natural climate variability, largely outweigh the effects of aerosol reductions.
A deep learning framework called PRTS accurately predicts single-cell-resolution spatial transcriptomics from H&E-stained histology images. The model identifies 21 cell subtypes in mouse brain and maintains prediction accuracy in human breast and lung cancer tissues.
Flinders University researchers discovered a biological process that could explain some stillbirths and pave the way for early detection. The study found that molecules called circular RNAs build up in the placenta too quickly during pregnancy, compromising its ability to nourish the baby.
A study by Professor Jane Ogden highlights the profound impact of family dynamics on eating behaviour, including traditional influences and tensions. She offers practical advice to promote a balanced approach, focusing on moderation rather than restriction, and encourages self-compassion to overcome guilt and shame associated with food.
A team from Tokyo Metropolitan University has uncovered the sequence of events in the formation of hexaniobate clusters, revealing a precursor's vital role in rapid catalyst formation. This insight promises finer control over an industrially important technology for speeding up chemical synthesis.
UT Health San Antonio received $3 million in CPRIT grants to expand access to preventive salpingectomy, test novel methods to prevent liver cancer, and advance treatment for therapy-resistant metastatic breast cancer. These projects aim to improve cancer prevention, diagnosis, and treatment in South Texas.
Researchers will investigate how HIV and cancer drugs damage brain cells over time, identifying potential early biomarkers of neurotoxicity. They will use human brain organoids grown in the lab to mimic brain physiology.
A new international study discovers that combining biochar with straw can reduce carbon emissions, boost soil health, and encourage microbes to work together. The research bridges Moscow and Guangzhou, delivering one of the clearest pictures yet of how organic amendments shape the hidden world beneath our feet.
Researchers developed RNACOREX, a new open-source software tool that identifies gene regulation networks in cancer. The tool analyzes thousands of molecules simultaneously to detect key interactions, providing an interpretable molecular map that improves understanding of tumors.
The Third Symposium on New Contaminant Control highlighted emerging pollutants like persistent organic pollutants, endocrine disruptors, and microplastics as a global challenge. The event emphasized the need for collaborative research and technology deployment to protect public health and environmental quality in China and beyond.
The American Meteorological Society (AMS) urges the US government to maintain and strengthen NSF NCAR, a critical resource for weather forecasting and climate science. This would lead to further forecast improvements that benefit the nation's safety and economy.
Insilico Medicine showcases its Pharma.AI platform's capabilities in generating biologics and analyzing data to accelerate drug discovery. The company's latest updates include improved Generative Biologics, Chemistry42/Nach01, and PandaOmics features.
CORAL accurately predicts genetic subtypes and patient outcomes in multiple myeloma without costly genomic tests. The technology could be applied to other cancers, opening the door to personalized, faster and widely accessible cancer care.
Researchers describe first reported mpox transmission of clade Ib in a healthcare setting outside Africa, with Ireland's nosocomial outbreak linked to local cases. In the Democratic Republic of Congo, community transmission shifted from sexual to non-sexual routes, driven by factors like overcrowding and child malnutrition.
Exposure to extreme heat during pregnancy quadruples the risk of child health problems, especially when combined with high humidity. The added weight and hormonal changes in pregnant women make them more susceptible to heat stress.
Manhattan E. Charurat, Ph.D., MHS has been invested as the Homer and Martha Gudelsky Distinguished Professor in Medicine at the University of Maryland School of Medicine. He is recognized for his scientific contributions and dedication to global health equity.
Dr. Julio J. Ramirez has been awarded the 2025 Innovative Leadership Award by AIBS for his exceptional leadership in mentoring and promoting inclusive science environments. Over his career, he has received numerous awards and mentored over 150 students, including a Presidential Award from President Obama.
A new study found that a widely used genomic test can accurately identify African American men with early prostate cancer at high risk of recurrence. The Decipher classifier linked to faster recurrence rates and supports more personalized treatment choices. Genomic testing may help better match patients with the right treatment intensi...
New research reveals that DNA's physical property of supercoiling is crucial for cells to respond to oestrogens. The study found that enzymes called topoisomerases regulate DNA coiling and activate target genes.
A study published in Science Advances explores the impact of mountain building and climate cooling on alpine biodiversity, revealing that these processes are key drivers of rich plant diversity. The research found that mountain uplift and cooler global temperatures enabled plants to evolve into new species and connect isolated regions.
The Advanced Photonics Young Innovator Award honors outstanding papers published in SPIE-CLP's journal over the past five years. Seven recipients are celebrated for their diverse range of innovative research, which shapes the future of optics and photonics.
Research reveals that low doses of nanoplastics can alter gut and liver function, with diet playing a key role. The study found that exposure to nanoplastics disrupted fat metabolism and glucose intolerance, especially in mice on Western-style diets.
The Baveno VII consensus guidelines have reshaped portal hypertension management, focusing on early intervention and noninvasive diagnostics. Nonselective beta-blockers and transjugular intrahepatic portosystemic shunt (TIPS) are recommended for clinically significant portal hypertension diagnosis.
Denise Antunes da Silva, a senior R&D staff member at Oak Ridge National Laboratory, has been elected a Fellow of the American Ceramic Society. She is recognized for her sustained excellence in building envelope materials science and meaningful service to the scientific community.
The conference will focus on mathematical and statistical foundations, data-driven approaches, and computational advances in uncertainty quantification. Major themes include applications in biology, medicine, environmental sciences, decision making for societal benefit, and physical science and engineering.
Researchers have created a design framework for magnetic cloaks that can protect sensitive electronics and sensors from magnetic interference. The new concept enables shielding of components in fusion reactors, medical imaging systems, and isolating quantum sensors.
The study uses a numerical model to simulate encounters between Neanderthals and modern humans on the Iberian Peninsula. Climate fluctuations significantly influenced population dynamics, with mixing possible in certain regions. The research offers a broader explanatory framework for interpreting archaeological and genomic data.
A study published in the Journal of Proteome Research found that acute systemic inflammation causes region-specific metabolic disruption in the cerebrum, impairing neuronal metabolism. Key findings include reduced NAA levels and elevated urea accumulation, suggesting a link between inflammation and neurodegenerative disorders.
Research highlights the importance of owner individual resilience and entrepreneurial orientation in driving organisational resilience in small independent retailers. The study reveals that these factors enhance innovation and business performance, leading to improved adaptability and responsiveness to market changes.
Researchers at participating UK institutions will benefit from a renewed and expanded agreement offering over 2,400 journals with open access publishing options. The partnership also enables the expansion of AI use in licensed Taylor & Francis proprietary content for non-commercial research and educational purposes.
Soil fungal agents can accelerate plant growth and stabilize microbial networks during initial vegetation establishment. Bacterial biomass increases over time, promoting nutrient cycling and maintaining ecosystem stability.
A new study synthesizes multinational research across five countries, finding that teacher noticing varies significantly across different cultural settings. The analysis emphasizes the importance of culturally responsive noticing, valuing diverse student thinking and participation.
The study found that consuming bananas grown in soil impacted by iron mining waste poses a possible health risk to children aged six years or younger. The team correlated the risk to human health with the transfer of toxic elements from the soil to the plant, revealing high concentrations of cadmium, chromium, and other metals.
A University at Buffalo researcher has developed a framework to help scientists incorporate community input into Earth system models, providing more accurate and relevant regional climate data. The framework outlines four levels of co-design, allowing modelers to incorporate local knowledge and observations directly into the model.
Agricultural practices like wheat straw incorporation and nitrogen fertilization significantly increase antibiotic resistance gene abundance and dissemination potential in soil. Research shows that these practices can enhance the spread of ARGs, posing a threat to human health through the soil-plant system.
A study found that warming and increased precipitation weaken soil multifunctionality in semiarid grasslands by intensifying competition between bacteria and fungi. The researchers' findings showed a decline in microbial diversity, changes in fungal community structure, and reduced network complexity.
A comprehensive analysis of 503 fish found high levels of 13 heavy metals and toxic substances, making consumption inadvisable due to health risks. The study highlights the persistence of contamination in the Doce River basin, with ongoing mineral exploitation and industrial activities contributing to pollution.
A new study reveals that COVID-19 vaccination influences long-term immunity, with those vaccinated first showing stronger antibody responses to Omicron variants. The study found higher levels of IgG and IgA antibodies in vaccinated individuals, but a stronger T-cell response in those infected first.
A large-scale measurement campaign with over 500 seismic stations has produced the first high-resolution image of the structures beneath the Eifel volcanoes. The data reveals a magma reservoir deeper and differently oriented than previously assumed, with surprising findings on recent microearthquakes and fluid accumulations in the crust.
Research reveals that negotiation avoidance is the norm, with 95% of individuals choosing not to negotiate up to 51% of the time. To overcome this mindset, experts emphasize the importance of understanding one's position, creating room for concessions, and developing strong relationships.
A new deep learning method uses YOLOv8 to automate Collembola identification, reducing identification time from hours to seconds. This innovation enables ecologists and policymakers to make data-driven decisions on soil management, while opening doors for studying other cryptic soil fauna.
The mecoturn R package supports various statistical analyses of microbial turnover along gradients, filling a gap in data analysis tools for microbial ecology research. It includes data transformation, statistical analysis, and visualization methods, particularly expanding linear mixed-effects models for beta diversity analysis.
Researchers found that fungal denitrification dominates soil N2O emissions after vegetation restoration in the Karst region, with higher sand content and acidic environment favoring fungal growth. This unique 'cross-scale' survival strategy gives fungi a competitive advantage over bacteria in coarse-textured soils.
Experimental particle physicists at Fermilab's MicroBooNE experiment found evidence against a 'sterile' type of neutrino, which was previously thought to be responsible for anomalous results. The research hones the search for alternative explanations, shedding light on fundamental physics questions.
Two US-based teams, FigureTwo and Syntheos, have won Digital Science's 2025 Catalyst Grant for their innovative data visualization projects. FigureTwo transforms static figures into interactive visuals, while Syntheos maps ideas across research communities to show impact.
The Organometallic Chemistry and Homogeneous Catalysis group develops multisensitive catalysts with switchable properties using naphthalene diimides and N-heterocyclic carbenes. This simplifies catalyst optimisation, enabling a single catalyst to facilitate various chemical transformations.
A new study proposes a machine-learning-guided strategy to improve high-temperature proton exchange membrane fuel cells (HT-PEMFCs) for aviation. The researchers designed a gradient dual-proton-conducting system that enables single cells to achieve record power densities at 160°C while maintaining long-term operational stability.
Research shows that ants with less protective armor, such as cuticle investment, tend to have larger colony sizes and are more successful in terms of diversification rates. This suggests that complex societies like humans may evolve by sacrificing individual quality for collective power.
A recent study reveals how ancient viral DNA, specifically the MERVL element, plays a crucial role in early embryonic development. Activating this element is sufficient to create totipotent features in early embryos, but its precise contribution is not well understood.
A new University of Stirling study shows that using insects like parasitic wasps to control agricultural pests is safer and more environmentally friendly than using chemical pesticides. Despite some whiteflies developing genetic resistance, the study found that survivors have low reproductive success, limiting widespread resistance.
Researchers discovered a link between increasing biomarker levels and cognitive decline, with a potential repurposed drug slowing damage. The study found exponential increases in UCH-L1 and GFAP levels with age, suggesting underlying neuroinflammation may contribute to Alzheimer’s disease.