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Covid-19 infections in nursing homes: Simulation model for optimal prevention and vaccination strategies

Austrian researchers developed a detailed epidemiological model to study the spread of coronavirus in nursing homes. The agent-based simulation tool helps balance safety and quality of life, considering vaccination rates and testing accuracy. With a high vaccination rate, major outbreaks are no longer expected.

SourceGraz University of Technology·JournalJournal of The Royal Society Interface·TypeComputational simulation/modeling·DateDec 22, 2021

Large field hospital study shows rapid Covid-19 test compares solidly with PCR detection

A large field hospital study shows that a rapid Covid-19 test is as accurate as PCR detection, with high sensitivity rates for both symptomatic and asymptomatic patients. The rapid antigen test's ease of use, time savings, and cost effectiveness make it an ideal solution to reduce testing disparities in medically underserved communities.

SourceJohns Hopkins Medicine·JournalMicrobiology Spectrum·DateDec 7, 2021

Data can help address health disparities

A local health department in Indiana used surveillance data to identify neighborhoods with high disease burden and set up test sites, resulting in a decline in new cases among targeted groups. The success of this intervention highlights the importance of using data to address systemic racism and promote health equity.

SourceRegenstrief Institute·JournalAmerican Journal of Public Health·DateDec 2, 2021

Well-known drug could help the most severely affected Covid-19 patients in intensive-care departments

A study published in the American Journal of Respiratory and Critical Care Medicine found that prostacyclin treatment reduced damage to vital organs and halved mortality rates among critically ill Covid-19 patients. The research team hopes to investigate larger patient populations in future studies.

SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalAmerican Journal of Respiratory and Critical Care Medicine·TypeRandomized controlled/clinical trial·DateNov 29, 2021

Same day test identifies secondary infections in COVID-19 patients

A rapid same-day test has been developed to identify secondary infections in COVID-19 patients on intensive care, allowing for targeted antibiotic treatment and reduced risk of antimicrobial resistance. The test uses nanopore sequencing technology to analyze bacterial and fungal pathogens present in patient samples.

SourceNIHR Biomedical Research Centre at Guy’s and St Thomas’ and King’s College London·JournalGenome Medicine·TypeRandomized controlled/clinical trial·DateNov 16, 2021

Airborne Detection

Researchers at East Carolina University have discovered a new way to detect SARS-CoV-2 by testing air passing through building ventilation systems. The method revealed the presence of the virus in air samples with high accuracy, potentially leading to earlier detection and reduced transmission.

SourceEast Carolina University·JournalAmerican Journal of Infection Control·DateNov 10, 2021

Rapid COVID-19 tests using saliva could be easier alternatives

Researchers found that rapid antigen tests can detect COVID-19 in saliva samples with high sensitivity early in infection, but later in infection the tests lose sensitivity. Saliva-based tests may offer a more comfortable and convenient option for diagnosing COVID-19, especially in children or younger unvaccinated students.

SourceLund University·JournalInfection Ecology & Epidemiology·DateNov 10, 2021

Coronavirus: Minimal transmission risk when playing football

A study by the Universities of Basel and Saarland found almost no risk of coronavirus infection in football players, contradicting previous assumptions about team contact risks. The research team collected data from over 1,300 cases and concluded that outdoor sports with minimal physical contact pose a very low risk of infection.

SourceUniversity of Basel·JournalBritish Journal of Sports Medicine·DateNov 2, 2021

Association for Molecular Pathology leaders publish recommendations to improve diagnostic testing response for current COVID-19 pandemic and future emerging outbreaks

The Association for Molecular Pathology (AMP) has published new guidelines to improve the US' ability to respond to emerging infectious disease outbreaks. The recommendations focus on better collaboration between public health, clinical laboratories, and government agencies.

SourceAssociation for Molecular Pathology·JournalJAMA Health Forum·DateNov 1, 2021

The Lancet Infectious Diseases: CoVID-19 vaccines lower risk of infection with delta variant, but infection can still be passed on in household settings

A study published in The Lancet Infectious Diseases found that COVID-19 vaccines reduce the risk of infection with the delta variant, but vaccinated people can still spread the virus in household settings. Vaccination remains effective at preventing severe disease and deaths from COVID-19.

SourceThe Lancet·JournalThe Lancet Infectious Diseases·TypeObservational study·DateOct 28, 2021

Study finds genetic markers may predict severity of COVID-19 infection

Scientists at the University of Colorado School of Medicine have identified specific genetic biomarkers in blood samples that can indicate the severity of COVID-19. The study's findings suggest that these signals can be used to monitor SARS-CoV-2 status and predict clinical outcomes.

SourceUniversity of Colorado Anschutz Medical Campus·JournalCommunications Medicine·TypeRandomized controlled/clinical trial·DateOct 26, 2021

Disease outbreak simulations reveal influence of “seeding” by multiple infected people

A new analysis suggests that the continuous arrival of infected individuals has a significant influence on the evolution and severity of local outbreaks. The researchers found an association between the number of seed arrivals and the speed of spread, final number of people infected, and peak incidence rate.

SourcePLOS·JournalPLOS Computational Biology·TypeComputational simulation/modeling·DateOct 14, 2021

Shrinking waveforms on electrocardiograms predict worsening health and death of hospitalized COVID-19 and influenza patients

Researchers found that shrinking waveforms on electrocardiograms can help identify high-risk patients with COVID-19 or influenza, allowing for more aggressive monitoring and treatment. The study also showed that this technique may be particularly useful in overwhelmed systems where timely intervention is crucial.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalThe American Journal of Cardiology·TypeData/statistical analysis·DateSep 24, 2021

Mathematical constructions of COVID virus activity could provide new insight for vaccines, treatment

Researchers developed a mathematical model to study the action of SARS-CoV-2, enabling the examination of individual virus particles and their spikes. This analysis can help fine-tune prevention and treatment by providing insights into viral load, spike distribution, and cell infection potential.

SourceMedical College of Georgia at Augusta University·JournalJournal of Mathematical Analysis and Applications·DateSep 23, 2021

Hopkins Med news update

Researchers discovered that new mutations in the BRAF gene can lead to gliomas growing back after treatment, suggesting personalized approaches to therapy. The study also explored potential impacts of COVID-19 vaccines on menstruation.

SourceJohns Hopkins Medicine·JournalClinical Cancer Research·DateSep 23, 2021