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Scientific consortium established by national institutes of health provides real-time risk assessment of SARS-CoV-2 variants on immune protection

The SAVE program, a NIH initiative, provides real-time risk assessment of SARS-CoV-2 variants on immune protection. It uses a coordinated approach to identify and curate data about these variants, their impact on immunity, and their effects on vaccine protection.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature·TypeCommentary/editorial·DateMar 31, 2022

IgA antibodies seem to protect unvaccinated against COVID-19

A University of Gothenburg study found that IgA antibodies present in the respiratory tract protected healthcare workers from contracting COVID-19. The research, published in the European Journal of Immunology, suggests that these antibodies may play a crucial role in preventing severe illness and hospitalization.

SourceUniversity of Gothenburg·JournalEuropean Journal of Immunology·TypeObservational study·DateMar 24, 2022

How does COVID-19 affect people’s ability to smell

Researchers found a nearly 16-fold higher prevalence of olfactory cleft abnormalities in patients with COVID-19 and olfactory dysfunction compared to controls. The blockages are expected to resolve with time, but nerve damage may be more difficult to recover from.

SourceWiley·JournalThe Laryngoscope·DateMar 23, 2022

Development of semiconductor microchip that can detect prostate cancer markers with ultra-high sensitivity

Researchers at Toyohashi University of Technology developed a microchip capable of detecting ultra-low concentrations of prostate cancer antigens using flexible nanosheets. The chip's lower detection limit is comparable to that of large testing devices, enabling fast and accurate diagnosis.

SourceToyohashi University of Technology (TUT)·JournalSensors·TypeExperimental study·DateMar 3, 2022

Human choices in a simulated pandemic: New study tests interventions to foster safer behaviour

A new study found that clear and consistent messaging is key to reducing risk-taking behavior, while personality-based approaches are less effective. The research used a simulated pandemic game to test different interventions and demonstrates the potential for behavioral sciences to inform public health policy.

SourceUniversity of Plymouth·JournalScience Advances·TypeExperimental study·DateFeb 25, 2022

COVID-19 infection detected in breath tests

A new study from the University of Gothenburg detects SARS-CoV-2 coronavirus particles in microscopically small fluid droplets exhaled by patients with COVID-19. The findings show that a few breaths are sufficient to detect viral RNA, offering potential for easy and convenient breath tests.

SourceUniversity of Gothenburg·JournalInfluenza and Other Respiratory Viruses·TypeRandomized controlled/clinical trial·DateFeb 22, 2022

Trust clinical COVID-19 signs over a negative RT-PCR test

A Rutgers study found that hospital patients with repeated negative RT-PCR tests but exhibiting COVID-19 signs and/or symptoms were half as likely to receive treatment as those who tested positive. The study suggests that clinicians should not solely rely on RT-PCR tests for COVID-19 diagnosis.

SourceRutgers University·JournalBMC Infectious Diseases·TypeObservational study·DateFeb 14, 2022

CityU scientist invents novel droplet manipulation method “WRAP”

Researchers at City University of Hong Kong have developed a novel droplet manipulation method called WRAP, which can transport micro-sized droplets using electromagnets or programmable electromagnetic fields. The method overcomes challenges in traditional magnetic actuation, such as contamination from added magnetic particles.

SourceCity University of Hong Kong·JournalNature Communications·TypeExperimental study·DateFeb 11, 2022

Study of U.S. employees defines the odds of COVID-19 reinfection

A new US-based study published in PLOS Biology found that most people who have had COVID-19 are protected against reinfection for at least six months. The research analyzed data from 4,441 SpaceX employees and estimated an odds ratio of 0.14 to 0.28 for reinfection depending on the time period considered.

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateFeb 10, 2022

Biologists isolated the coronavirus nucleoprotein in its pure form to improve the accuracy and sensitivity of the antibody tests

Biologists isolated the SARS-CoV-2 nucleoprotein in its pure form to create more accurate antibody tests. The new approach significantly improves sensitivity, increasing the ability to detect antibodies to the nucleoprotein. This breakthrough helps determine if vaccinated individuals have been infected with COVID-19.

Tracking SARS-CoV-2 during Tokyo 2020 via wastewater

A team of researchers used wastewater-based epidemiology to detect SARS-CoV-2 in more areas of the Olympic village than clinical testing indicated. The study found that daily screenings missed asymptomatic and post-quarantine patients, highlighting the need for alternative methods.

SourceHokkaido University·JournalJournal of Travel Medicine·TypeExperimental study·DateFeb 3, 2022

Dartmouth study assesses how consumers interpret and act on results from at-home COVID-19 self tests

A Dartmouth study reveals that consumers using at-home COVID-19 self tests may misinterpret the implications of their test results, leading to either unnecessary or inadequate quarantine. The study suggests that individuals at high risk for infection should still quarantine after a negative test result.

SourceThe Geisel School of Medicine at Dartmouth·TypeRandomized controlled/clinical trial·DateJan 31, 2022

Special testing of kidney tissue from deceased COVID-19 donor documents safe transplantation of the organ, Johns Hopkins researchers report

Researchers at Johns Hopkins Medicine have successfully transplanted a kidney from a COVID-19 donor, demonstrating that healthy kidneys from such donors can be safely transplanted. The recipient has shown no signs or symptoms of the virus and has excellent kidney function since the transplant.

SourceJohns Hopkins Medicine·JournalAmerican Journal of Transplantation·DateJan 31, 2022

Pulse oximeter measurements of blood oxygen levels are unreliable in assessing severity of Covid-19 pneumonia across different ethnic groups

A study published in European Respiratory Journal found pulse oximeters give false readings of up to 7% higher in patients with Mixed, Black, and Asian ethnicities compared to White patients. This can delay timely treatment for Covid-19 pneumonia, leading to poorer outcomes.

SourceUniversity of Nottingham·JournalEuropean Respiratory Journal·TypeExperimental study·DateJan 27, 2022

New, better coronavirus rapid test

The new test, developed at the Paul Scherrer Institute, uses a novel functional principle to provide reliable results on Covid-19 disease progression and its course. It can also detect other diseases and Covid variants, offering more predictive power than existing rapid antigen tests.

SourcePaul Scherrer Institute·JournalACS Applied Nano Materials·TypeExperimental study·DateJan 24, 2022

More than a third of care home residents in England caught Covid-19 in early waves of pandemic

A UK study found that over a third of care home residents and a quarter of staff in England showed evidence of SARS-CoV-2 infection during the first two waves of the pandemic. The study also revealed that antibodies against the virus became undetectable in half of the population within eight months.

SourceUniversity College London·JournalThe Lancet Healthy Longevity·TypeObservational study·DateJan 21, 2022

Why don’t people with COVID-19 symptoms get tested?

A new study of over 4 million adults in the UK found that people with COVID-19 symptoms are less likely to get tested due to barriers such as mild symptoms, poor knowledge of nearby testing sites, and certain demographic factors. The study suggests that targeted messaging and improved education are needed to increase test uptake.

SourcePLOS·JournalPLOS Global Public Health·TypeSurvey·DateJan 19, 2022

Chung-Ang University researchers shows a gold-paved path towards faster COVID-19 diagnosis

Researchers created a novel molecular diagnostic platform that can detect COVID-19 genes after only 8 cycles of amplification, significantly reducing the time required for diagnosis. The new SERS-PCR platform uses gold nanoparticles to produce high-sensitivity signals, providing an important tool in the fight against the pandemic.

SourceChung Ang University·JournalBiosensors and Bioelectronics·TypeExperimental study·DateJan 19, 2022

New label-free detection technique digitally counts intact SARS-CoV-2 virus particles in saliva or exhaled breath

Researchers have developed a label-free detection technique that digitally counts intact SARS-CoV-2 virus particles in saliva or exhaled breath. The approach uses an aptamer attached to a biosensor to selectively recognize and capture viruses, providing lower cost and reduced time to diagnose infections.

SourceUniversity of Illinois Grainger College of Engineering·JournalJournal of the American Chemical Society·DateJan 18, 2022

One in 10 people may still be infectious for COVID after 10 days, new research indicates

A new study by the University of Exeter found that 13% of people who tested positive for COVID-19 on standard PCR tests remained clinically relevant for the virus beyond 10 days. This could pose a risk of onward transmission, and the authors recommend applying the newly adapted test to settings where vulnerable individuals are present.

SourceUniversity of Exeter·JournalInternational Journal of Infectious Diseases·TypeExperimental study·DateJan 13, 2022

Development of rapid and simultaneous diagnosis of COVID-19/influenza diseases by manipulating microfluidic flow with a microfluidic chip

Researchers developed a microfluidic chip for rapid and simultaneous diagnosis of COVID-19 and influenza diseases, achieving results within 30 minutes. The device uses the LAMP method for genetic amplification and has potential applications in various fields beyond human infectious diseases.

SourceToyohashi University of Technology (TUT)·JournalLab on a Chip·TypeExperimental study·DateJan 4, 2022

A potential at-home COVID-19 test is just as good as laboratory PCR tests, according to preclinical data

Researchers have developed an at-home COVID-19 test with a high-quality assay that can detect the virus with similar reliability to laboratory-based molecular tests. The new test uses loop-mediated isothermal amplification and has unique advantages, such as speed and direct detection of viral RNA in saliva.

SourceUniversity of Illinois Chicago·JournalEBioMedicine·TypeExperimental study·DateJan 3, 2022