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World’s first open access dashboard revealed Tempe, Ariz. neighborhood-level trends of COVID-19 from wastewater-based epidemiology

The City of Tempe and Arizona State University have developed a unique partnership to track COVID-19 using wastewater-based epidemiology, providing early warning data for municipalities. The system has been shown to reliably predict SARS-CoV-2 levels in city ZIP codes up to 11 days ahead of clinical testing results.

SourceArizona State University·JournalThe Lancet Microbe·TypeExperimental study·DateDec 7, 2022

Long COVID patients and those with other illnesses experience similar, negative lingering effects during the pandemic

Research suggests that long COVID patients share similar lingering negative effects on physical, mental, and social well-being with individuals who have other illnesses. The study found moderate-to-severe residual symptoms in 40% of COVID-positive participants and 54% of those who tested negative.

SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateDec 1, 2022

Adding to Europe’s HIV testing gap: Lack of testing recommendations in national guidelines on HIV indicator conditions

A systematic review of national clinical practice guidelines in Europe found that fewer than half include HIV testing recommendations for patients with medical conditions indicating HIV infection. This omission hinders efforts to stop the spread of HIV through timely diagnosis, affecting the lives of people living with HIV.

SourceEuropean Centre for Disease Prevention and Control (ECDC)·JournalEurosurveillance·TypeLiterature review·DateDec 1, 2022

In some settings, medical masks may offer similar effectiveness to N95 respirators for preventing COVID-19 infection among health care workers

A study of over 1,000 healthcare workers found that medical masks may be as effective as N95 respirators in preventing COVID-19 infection. However, the results varied across countries and were influenced by factors such as vaccine use and variant circulating during the pandemic.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeRandomized controlled/clinical trial·DateNov 28, 2022

New Omicron subvariant BQ.1.1 resistant to all therapeutic antibodies

A recent study found that the Omicron sub-lineage BQ.1.1 is resistant to all approved antibody therapies, posing a risk to high-risk patients. The researchers emphasize the importance of developing new antibody therapies specifically targeted at currently circulating and future viral variants.

SourceDeutsches Primatenzentrum (DPZ)/German Primate Center·JournalThe Lancet Infectious Diseases·TypeExperimental study·DateNov 23, 2022

COVID-19 vaccine gives substantial protection against reinfection

A new study published in PLOS Medicine found that COVID-19 vaccination provides significant protection against reinfection, with varying levels of effectiveness (60-94%) across different variants. The study analyzed data from over 200,000 people in Denmark and showed that vaccination offered up to 71% protection during the Alpha period...

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateNov 22, 2022

Handheld diagnostic lab offers point-of-care solution for future pandemics

A handheld diagnostic lab developed by UCLA researchers can fully automate pooled testing and detect multiple diseases, reducing costs and usage of scarce supplies. The technology can be easily manufactured, deployed, and performed at a doctor's office or mass testing sites, helping authorities prepare for future pandemics.

SourceUniversity of California - Los Angeles·JournalNature·TypeExperimental study·DateNov 10, 2022

Artificial intelligence could help ease hospital pressures

A new AI technology has been developed to automatically diagnose lung diseases such as tuberculosis and pneumonia, freeing up radiographers and reducing waiting times for test results. The system, which uses X-ray imaging and deep learning algorithms, achieved a 98% accuracy rate during extensive testing.

SourceUniversity of the West of Scotland·JournalComputer Methods and Programs in Biomedicine·TypeComputational simulation/modeling·DateNov 6, 2022

Climate change could make High Arctic fertile ground for emerging pandemics: uOttawa study

A novel genetic analysis by University of Ottawa researchers reveals that climate change could lead to an increased risk of viral spillover in the High Arctic. This increased risk may result in new viruses infecting previously uninfected hosts, potentially leading to emerging pandemics.

SourceUniversity of Ottawa·JournalProceedings of the Royal Society B Biological Sciences·TypeComputational simulation/modeling·DateOct 19, 2022

COVID-19 vaccine developed by Brazilian scientists is ready for clinical trials

A novel COVID-19 vaccine developed by Brazilian scientists combines two SARS-CoV-2 proteins to trigger a cellular immune response. The vaccine, called SpiN, showed promise in animal trials, protecting against three strains of the virus and reducing viral load by up to 50 times.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalNature Communications·TypeRandomized controlled/clinical trial·DateOct 6, 2022

Method for detecting waves of COVID-19 infections can shape critical public health decisions during a pandemic

A method combining local health department data and hospital records identifies new COVID-19 outbreak waves, helping inform public health strategies. Researchers detected two large waves in Harris County, with the second taking longer to spread, highlighting the importance of continuous monitoring and community collaboration.

SourceUniversity of Texas Health Science Center at Houston·JournalScientific Reports·TypeComputational simulation/modeling·DateOct 4, 2022

As few as 1 in 5 COVID cases may have been counted worldwide, mathematical models suggest

Mathematical models suggest that only 1 in 5 COVID-19 cases were counted worldwide, resulting in an estimated 600 million to 2.4 billion actual cases globally. The wide range of estimated cases highlights the problems with accuracy of reported numbers due to data tampering, inconsistent reporting, and lack of uniformity.

RNA-editing tool a fast, sensitive test for COVID-19

Researchers developed an engineered Cas13 system that detects SARS-CoV-2 in biological samples with high sensitivity and speed. The new platform outperforms traditional PCR testing, finding 10 out of 11 positives and no false positives in clinical samples.

SourceRice University·JournalNature Chemical Biology·TypeExperimental study·DateSep 22, 2022

Novel method to predict behavior of different COVID-19 waves in the vaccinated or previously infected

Researchers developed a faster, more affordable method to analyze serological data and predict COVID-19 wave behavior. The study showed that vaccination boosted immunity, with hybrid immunity producing higher protection levels. Antibody levels rose quickly after the first dose, especially in cities where case numbers were highest.

SMART and NTU Singapore develop a quick test kit to determine a person’s immunity against COVID-19 and its variants

A team of scientists from SMART and NTU Singapore has developed a rapid point-of-care test kit that measures antibodies against SARS-COV-2 and its variants, offering personalized vaccination strategies. The test kit requires just 10 minutes to show results and has up to 93% accuracy.

SourceSingapore-MIT Alliance for Research and Technology (SMART)·JournalMicrobiology Spectrum·TypeNews article·DateSep 21, 2022

SMART and NTU Singapore develop a quick test kit to determine a person’s immunity against COVID-19 and its variants

A team of scientists from SMART and NTU Singapore has developed a quick test kit that can determine a person's immunity against COVID-19 and its variants based on antibodies detected in a blood sample. The test kit, which requires just 10 minutes to show results, can be easily adapted for new variants of concern and other diseases.

SourceNanyang Technological University·JournalMicrobiology Spectrum·TypeRandomized controlled/clinical trial·DateSep 21, 2022

Lessons learned in COVID-19: SHEA offers guidance for antibiotic use in a pandemic

The Society for Healthcare Epidemiology of America highlights the need to strengthen antibiotic stewardship programs to address overuse of antibiotics in early stages of viral epidemics. The guidance provides strategies for hospitals and healthcare personnel to improve antibiotic prescribing and diagnostic testing.

SourceSociety for Healthcare Epidemiology of America·JournalInfection Control and Hospital Epidemiology·TypeLiterature review·DateSep 14, 2022

Significant risk of sensory loss in long COVID - study

A new study published in Frontiers in Medicine found that around 30% of people with long COVID experience a decreased sense of smell, with 29.9% reporting persistent anosmia after 12 weeks. Researchers also discovered an elevated prevalence of blurred vision and hearing-related symptoms after three months.

SourceAnglia Ruskin University·JournalFrontiers in Medicine·TypeLiterature review·DateSep 9, 2022

High cholesterol, overweight and reduced physical stamina are long COVID sequelae in young adults

A new study found that young Swiss military personnel with confirmed Covid-19 infections experienced symptoms like fatigue, reduced sense of smell, and psychological problems for up to 180 days. Long-term effects included increased BMI, high cholesterol, and lower physical stamina, suggesting a higher risk of metabolic disorders and ca...

SourceUniversity of Zurich·JournalThe Lancet Infectious Diseases·TypeData/statistical analysis·DateSep 5, 2022

NIH-funded pediatric COVID-19 testing study finds school-aged children can self-swab

A new study found that school-aged children can successfully use a nasal swab to obtain their own COVID-19 test specimen, providing data for recommendations on self-swabbing in schools and other settings. The study showed that children as young as 4 years old can follow instructions and collect their own samples with high accuracy.

SourceNIH/National Institute of Biomedical Imaging & Bioengineering·JournalJAMA·TypeExperimental study·DateAug 26, 2022

Wastewater viral loads can provide advance warning of COVID-19 outbreaks

A study by Hokkaido University scientists found a close association between clinical cases of COVID-19 and viral loads in wastewater, with the viral loads picking up to two days before the cases were detected. The researchers used wastewater-based epidemiology to track the spread of SARS-CoV-2 in the Tokyo 2020 Olympics and Paralympics.

SourceHokkaido University·JournalJAMA Network Open·TypeExperimental study·DateAug 22, 2022

First real-world study gives detailed new insights into when people with COVID-19 are infectious

A study of 57 people with mild COVID-19 found that the average duration of infectiousness was five days, and two-thirds of cases remained infectious for at least five days after symptoms began. Lateral flow tests can safely shorten self-isolation by identifying when someone is no longer contagious.

SourceImperial College London·JournalThe Lancet Respiratory Medicine·TypeObservational study·DateAug 18, 2022

Scientists create a DNA test that identifies Lyme disease in horses

A Rutgers scientist has developed a highly sensitive DNA test that can detect Lyme disease in horses, a condition that can cause long-term complications. The test, called genomic hybrid capture assay, was tested on a sick horse and successfully identified the pathogen, allowing for early diagnosis and treatment.

SourceRutgers University·JournalJournal of Veterinary Diagnostic Investigation·TypeExperimental study·DateAug 17, 2022

A fast, accurate, equipment-free diagnostic test for SARS-CoV-2 and its variants

A team of researchers from Princeton University and the Broad Institute created a fast, accurate, and equipment-free diagnostic test for COVID-19. The test uses CRISPR technology to detect SARS-CoV-2 variants and can be performed at home without special equipment, improving sensitivity and specificity compared to existing tests.

SourcePrinceton University·JournalNature Biomedical Engineering·TypeExperimental study·DateAug 16, 2022