Articles tagged with Virus Testing
Researchers developed a SARS-CoV-2 saliva assay and prototype device combining speed, ease, and high sensitivity. The SLIDE device detects viral RNA in saliva within 45 minutes, comparable to traditional RT-PCR methods.
A study of 40 individuals found that the duration of COVID-19 symptoms was associated with positive home rapid antigen tests, with symptoms persisting longer in those with prolonged test positivity. The findings suggest that symptom duration may be a useful indicator for determining when to stop testing.
The new tuberculosis vaccine candidate VPM1002 shows its safety and efficacy in a study of HIV-exposed and non-HIV-exposed newborns. The vaccine has fewer side effects compared to the existing BCG vaccine, and elicits a similar immune response.
Researchers have developed a smartphone clip-on instrument that can rapidly detect Zika virus in whole blood using spatial RT-LAMP technology. The device is sensitive, accurate, and easy to use, making it ideal for point-of-care clinics and controlling the spread of infectious diseases.
A new study published in the International Journal of Public Health found that testing people at the door or immediately before social mixing can significantly reduce COVID-19 transmission. The research suggests that testing on the day of an event or even 12 hours prior to arrival can effectively limit the spread of the virus.
A recent study from University of East Anglia compared 13 face shield styles in laboratory settings and surveyed over 600 people in Nigeria and Brazil about their views on face shields as PPE. The results showed that all face shields provided some protection, but none gave high levels against external droplets.
Researchers at Columbia University and Rover Diagnostics have developed a low-cost, portable platform that provides RT-PCR results in 23 minutes, matching laboratory-based tests. The system uses plasmonic nanoparticles to achieve real-time and multiplexed RT-qPCR on clinical specimens.
Researchers at WVU are conducting a four-year study to investigate long COVID's impact on pediatric patients, exploring questions like prevalence, symptoms, and treatment options. The study will enroll children from infancy to 25 years old and analyze biomarkers for long COVID susceptibility.
A new study from Texas A&M University uses drone delivery to quickly distribute at-home diagnostic tests, minimizing exposure to others and reducing transmission rates. The approach can reduce transmission by a factor of 7.5 and has potential applications in other infectious diseases like influenza.
Researchers from Indiana University are developing a new biosensor that can analyze samples from 96 individuals in under three hours, with a sensitivity rate of 100% and specificity rate of 90%. The sensor detects not only the virus's spike protein but also the proteins created by the body to protect against the virus.
Researchers found a flaw in Google/Apple's exposure notification framework that can be exploited for replay attacks, potentially causing false positive notifications and disrupting trust in the system. A patch, called GAEN+, has been developed to address this issue using coarse location data from Wi-Fi access points and cell phone towers.
Researchers developed a new blood test that can indicate cellular immunity to SARS-CoV-2 within 48 hours. The test distinguishes between post-infection and post-vaccination immunity, enabling quick diagnosis for patients unable to produce antibodies. Long-lasting T-cell responses may protect against severe disease in re-infections.
A new study from Tel Aviv University found a promising treatment for long-term COVID-19 symptoms using Hyperbaric Oxygen Therapy (HBOT). Patients treated with HBOT showed significant improvement in cognitive function, attention, and executive functions.
A rise in severe acute hepatitis of unknown causes (SAHUC) in children has been reported worldwide, with symptoms including jaundice, vomiting, and diarrhea. Diagnostic tests such as liver enzymes and biopsy reports can help identify the disease, but its etiology remains unclear.
The NHS is facing a critical crisis due to the failure to recognize the ongoing threat of COVID-19. Weekly admissions for COVID-19 have averaged over 9,000, with elective activity 10% below pre-pandemic levels.
MU researchers have identified specific mutations in the Omicron variant's spike protein that help it evade existing antibodies from vaccines or previous COVID-19 infections. These findings can inform developers of COVID-19 treatments and vaccines, which may need to target different parts of the virus to produce effective outcomes.
Researchers found that frequent, regular rapid antigen testing, combined with isolating those who test positive, can effectively suppress COVID outbreaks. The study suggests that testing every other day can be as effective as a 24-hour turnaround PCR test in reducing transmission.
A longitudinal cohort study found significant reductions in liver disease and mortality among people with HCV infection who received treatment. The study's findings suggest that continued testing, treatment, and community-based interventions could lead to the elimination of HCV infection within the next decade.
Researchers at UC San Diego and Scripps Research developed a wastewater sequencing tool to track regional infection dynamics. This approach proved effective in identifying emerging variants and predicting COVID-19 surges, enabling early detection of cases and informing public health interventions.
A study found that Omicron's neutralization capacity outperforms its predecessors, even in vaccinated individuals. Antibody levels against ancestral SARS-CoV-2 are roughly 10 times higher in vaccinated people than those with natural immunity.
A heat-loving bacterium's Cas13 protein enables specific detection of SARS-CoV-2 and other viruses in a one-pot assay. The technology has been patented and clinically validated, with the aim of mass production and commercialization.
Researchers at The University of Tokyo have created a new antibody-based method for detecting SARS-CoV-2 that does not require a blood sample. This innovative approach uses interstitial fluid from human skin to detect antibodies within 3 minutes.
The new CoVarScan test detects SARS-CoV-2 variant signatures, providing accurate results in hours, unlike lengthy whole genome sequencing.
The study found that legislatures, rather than governors, played a crucial role in shaping data reporting practices. Standardized data collection protocols and comprehensive race and ethnicity data are essential for addressing health disparities and reducing information asymmetries.
Researchers found that college towns experienced lower COVID-19 case rates when classes were held online or accompanied by regular on-campus testing. This suggests that implementing regular testing could help mitigate future community infections in these settings.
Researchers used wearable activity trackers and AI to identify indicative physiological changes in people with COVID-19, detecting infections up to 2 days before symptoms began. The study found that the algorithm was effective in identifying positive cases, but its accuracy needs further improvement.
A balance test that measures an individual's ability to stand on one leg for 10 seconds can predict mortality risk in middle-aged and older adults. Researchers found that those who failed the test had a significantly higher risk of death from any cause within the next decade, with an absolute difference of nearly 13%.
A new method using the Vortex fluidic device can test hundreds of proteins in under 5 minutes, with data readable by a cell phone camera. This technology has the potential to improve diagnosis and treatment of diseases in remote areas, reducing mortality and morbidity.
Researchers have developed a novel fusion protein that enables the detection of SARS-CoV-2 antibodies using widely available glucose meters. The test was validated on various patient samples and found to be as accurate as four different ELISAs.
A recent study published in the New England Journal of Medicine found that COVID-19 vaccine immunity against new infection appears to wane rapidly, whereas people with a prior-infection were moderately protected from Omicron. Natural immunity provided strong and durable protection against severe illness.
A new study published in mSystems demonstrates that a surface sampling method can detect SARS-CoV-2 RNA on surfaces, improving environmental surveillance in public health labs.
A new study published in Microbiology Spectrum found that nasopharyngeal swabs were the most effective method for detecting COVID-19, with detection rates ranging from 92 to 100%. Saliva and anterior nares tests had lower detection rates, particularly in asymptomatic patients.
Researchers developed a nanoparticle sensor that can accurately distinguish between viral and bacterial pneumonia within two hours using a simple urine test. The sensor uses the host's immune response to infection, detecting specific protease patterns that serve as signatures of bacterial or viral infection.
Researchers developed a rapid blood assay that measures the magnitude and duration of immunity to SARS-CoV-2, allowing large-scale monitoring of population immunity. The test takes less than 24 hours to perform and is scalable to use broadly in the population.
Infants born to mothers with positive SARS-CoV-2 tests during pregnancy were more likely to receive neurodevelopmental diagnoses by 12 months, even after accounting for preterm delivery. Longer studies are needed to confirm these associations and understand the long-term effects of in utero COVID-19 exposure.
The SHIELD program employed rapid saliva testing, real-time data analysis, and fast reporting to mitigate the spread of COVID-19. The program's success led to a significant reduction in cases and deaths on campus, with Champaign County experiencing a third less COVID-19 cases than expected.
Researchers at Harvard Medical School used a new technique to analyze SARS-CoV-2 samples from university screening programs and found that omicron accounted for over 90% of infections just nine days after arrival. The study suggests universities can serve as monitoring hubs for early detection of infectious disease outbreaks.
Researchers have developed a new tool that can quickly identify the presence of Ebola virus in blood samples, potentially leading to faster diagnosis and better outcomes. The technology uses optical microring resonators to detect tiny amounts of Ebola-related molecules at low levels.
A team led by UMass Amherst food scientist Matthew Moore has received a $750,000 grant to develop portable biosensors for detecting noroviruses and mycotoxins in foods. The technology aims to provide quick, cheap, and effective detection without lab testing.
A study published in PLOS ONE found that dogs can detect SARS-CoV-2 infections with high sensitivity (97%) and lower specificity (91%), even when patients are asymptomatic. The diagnostic accuracy of canine olfaction for non-invasive detection of COVID-19 was demonstrated in a clinical trial conducted in France and the UAE.
A retrospective analysis of 7,000 patients found pulse oximeter devices overestimated blood oxygen levels in non-White patients, delaying treatment eligibility recognition. The study suggests that biases in pulse oximeter accuracy disproportionately affect minority communities.
Researchers found that 80% of infections at superspreading events came from just 4% of infected individuals, known as index cases, who carried high viral loads. The study also identified the occupancy and ventilation in social contact settings as key factors driving variability in superspreader events.
A new method measures individually measurable aerosol values during exercise, revealing moderate aerosol emissions at medium exertion and exponential increases above that point. The study suggests special protective measures are needed for high-intensity training to reduce infection risk.
Research suggests that NF-κB over-activation is associated with improved outcomes in patients with HPV-positive head and neck cancer. An RNA-based classifier trained on tumors with specific mutations may improve prognostic classification, aiding in treatment personalization.
A population-scale study found COVID-19 vaccination is effective in most cancer patients but offers lower protection and wanes quickly. Vaccine effectiveness was lower (65.5%) in cancer patients compared to the general population (69.8%), with higher hospitalization and death risks despite vaccination.
A new study reveals which bird species are driving the global spread of avian influenza, identifying ducks and geese as super-spreaders. The research also highlights the crucial role of gulls in transmitting the virus over long distances, with their ability to fly over oceans playing a significant role in its rapid spread.
A recent study by the University of Helsinki found that scent detection dogs can accurately identify individuals with a coronavirus infection from skin swabs. The dogs' sensitivity and specificity were 92%, with only small differences in accuracy observed between individual dogs.
Researchers have trained sniffer dogs to detect SARS-CoV-2 in airport passengers with high accuracy, comparable to PCR swab tests. The dogs' performance was found to be robust across various scenarios, including low prevalence populations, suggesting their potential for widespread use in screening.
The Center of BioModular Multi-Scale Systems for Precision Medicine develops rapid next-generation tests for human ailments like cancer and COVID-19 using saliva, urine, or blood samples. The technology has already helped patients through commercial partnerships with private firms.
Four rapid antigen tests were found to be less sensitive to the Delta variant than the Omicron strain. The study suggests that continuous assessment and updating are needed for these tests to remain effective in detecting COVID-19 infections. Continuous improvement is necessary to ensure they meet public health testing goals.
A new lab test has been developed by Rutgers scientists to identify COVID-19 variants. The test uses molecular beacon technology and can detect eight different mutations in the spike protein, increasing the transmissibility of the virus and evading immune defenses.
A recent study presented at the 2022 ARRS Annual Meeting found that COVID-19 infection significantly impacted lung cancer screening in diverse inner-city populations. The research revealed that approximately 9% of participants developed COVID-19 during the pandemic, with mortality rates reaching 6.9%.
Researchers tracked COVID-19 infection dynamics in adults over time, using repeated sampling and different testing methodologies. The study revealed factors influencing infection course and transmission risk, including viral genome loads and shedding times.
Researchers have found that preterm infants with certain viral signatures in their gut are at risk of developing necrotizing enterocolitis (NEC), a serious and often fatal disease. The study highlights the potential for early warning signals to alert clinicians, allowing emergency action to be taken.
Patients hospitalized with omicron required similar levels of respiratory support and intensive care as those with delta variants, according to a Johns Hopkins study. Omicron infections should not be underestimated due to comparable severe disease risks.
Researchers used symptom data from over 10 million participants to estimate regional COVID-19 prevalence and predict hospital admissions. The findings confirm previous reports that symptoms are related to community infection rates, providing a scalable tool for pandemic preparedness.
Researchers at Gwangju Institute of Science and Technology (GIST) have developed a new technique to easily visualize viruses using an optical microscope, called the Gires-Tournois immunoassay platform. The platform uses 'slow light' technology to detect coronavirus particles by slowing down light that gets reflected around them.
A new study assesses the degree and duration of protection against COVID-19 associated with natural immunity in 120,000 unvaccinated individuals. Researchers found that those who previously tested positive for SARS-CoV-2 had lower rates of subsequent COVID-19 infections.
A new portable COVID-19 test can detect and differentiate the alpha variant of the SARS-CoV-2 virus from earlier strains in saliva samples. The test uses a genetic phenomenon called S-gene target failure to identify the alpha variant, and can be used at home or other settings.
Researchers found that vaccination greatly reduces the infectious viral load caused by COVID-19 variants Delta and Omicron. However, boosted individuals showed a significant reduction in viral load compared to unvaccinated people. The study highlights the importance of updated knowledge for combating new variants.