Articles tagged with Viruses
Two outbreaks of respiratory illness in wild chimpanzees were identified, one lethal and the other non-fatal, caused by human metapneumovirus and parainfluenza virus 3. The viruses were found to be nearly identical genetically to common strains in humans, suggesting a human origin.
Researchers highlight diagnostic pitfalls in Zika and Chikungunya virus detection, particularly for Zika, where false positives can have fatal consequences. Combined testing methods offer higher reliability, with sensitivity improved through the use of Immunoglobulin A (IgA) as a marker.
A study using murine models found that a neutralizing monoclonal antibody, ZIKV-195, protects mice from Zika virus infection. The antibody targets and cross-links envelope proteins critical for viral membrane fusion.
Researchers discovered that viruses associated with the varroa mite have spilled over into the western yellowjacket, a honeybee predator, causing a change in genetic diversity. This finding suggests that introducing non-native species can have far-reaching effects on ecosystems.
Scientists have identified regions with high diversity of potential wildlife hosts for flaviviruses, including primates and birds. The study's model predicts hundreds of previously unobserved host species, which can help with disease detection and surveillance efforts.
A study by Michigan State University found that people with low self-control are more likely to fall victim to cybercrime involving Trojans, viruses, and malware. The research, which analyzed nearly 6,000 survey participants, identified impulsiveness as a key factor in increasing the risk of infection.
A recent study by RUDN medics revealed critical spread rates of five types of viral hepatitis in Somalia, with 18.9% of residents infected with hepatitis B and higher rates for hepatitis A and E. The researchers emphasize the need for immediate action to address this global health crisis.
Mayo Clinic researchers find that viruses can hijack the ADAR1 enzyme to avoid immune detection, but at a threshold of 1,000 double-stranded RNA molecules. This discovery offers hope for new antiviral therapies targeting ADAR1.
Researchers developed a model predicting animal viruses capable of spreading among humans, highlighting potential targets for disease surveillance. The study identified 47 viruses with high transmissibility potential, including Carnivore amdoparvovirus 1 and Simian Foamy virus.
Researchers isolated giant viruses from soil at Harvard Forest using a novel mini-metagenomics approach, revealing unprecedented biodiversity and challenging existing knowledge of viral diversity. The discovery highlights the importance of new methods in uncovering key discoveries in microbial ecosystems.
Researchers have discovered a possible path forward in preventing cancers linked to the Epstein-Barr virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV), which cause infectious mononucleosis. By blocking the viruses' defense proteins, it may be possible to treat mono and prevent cancer development.
A new study found that patients with bacterial pneumonia are at a 60% greater risk of a heart attack, stroke, or death compared to those with viral pneumonia. Researchers recommend aggressive treatment and close monitoring for patients with bacterial pneumonia, particularly those with pre-existing heart conditions.
A new study reveals that Anopheles mosquitoes, including species found in the US, can carry and transmit Mayaro virus, which causes fever, joint aches, and other symptoms. The researchers tested six mosquito species and found that all four Anopheles species were competent laboratory vectors of the virus.
A UC Riverside-led study deciphers the key elements for assembling large viruses, which may aid in interrupting their formation and containing viral diseases. The research uses continuum elasticity theory to explain how protein subunits arrange themselves into stable icosahedral structures with precision and symmetry.
Scientists have discovered how the Seneca Valley Virus interacts with tumor receptors, allowing it to selectively target cancer cells while sparing healthy tissues. The study provides detailed images of the virus and its receptor, enabling researchers to design improved cancer therapies.
Researchers have identified three chemicals that could develop into a new type of anti-cold drug by analyzing changes in cellular fat molecules during the infection process. By studying lipids, the researchers found changes to prevent key virus replication and limited further infection.
Scientists at NTU Singapore have engineered an antiviral peptide that exploits the Zika virus' viral membrane, reducing disease symptoms and deaths in infected mice. The peptide can cross the blood-brain barrier to tackle viral infection in mouse brains, a critical feature since Zika targets the brain and central nervous system.
A new study published in the Journal of Biological Chemistry has identified a human RNA molecule called nc886 as a potent activator of the innate immune system. The RNA molecule's ability to turn on protein OAS sets off a chain of events that destroys viruses.
A Phase II clinical trial found marked improvement in three patients with progressive multifocal leukoencephalopathy (PML), a rare and often fatal brain infection. Patients infused with donor T cells targeting the BK virus experienced significant reductions in JC viral load and clinical improvement.
Researchers at NC State have developed self-sterilizing antimicrobial materials that can inactivate bacteria and viruses using only visible-wavelength light. The new approach opens the door to a range of new products aimed at reducing the transmission of drug-resistant pathogens.
Researchers studying vampire bats and Morbillivirus aim to understand how viruses persist inside the body and trigger new infections. The project aims to gain fundamental insights into RNA virus persistence and potentially shed light on diseases like SSPE.
Researchers developed a cancer vaccine platform that can enhance oncolytic virus efficacy, activating human immune response against cancer cells. By using patient's own peptides, the treatment targets tumour cells, increasing T cell activity and improving therapy.
A study found that viruses influenced the evolution of humans, particularly in adapting to pathogens. Neanderthal DNA was shared with modern humans, providing resistance to viruses, and its presence suggests selective benefits.
A mushroom extract fed to honey bees greatly reduces virus levels, with a 79-fold reduction in deformed wing virus and a 45,000-fold reduction in Lake Sinai virus. The research shows promise for treating varroa mite-borne viruses and improving bee health.
A recent study by scientists at the Institut Pasteur has demonstrated that tiger mosquitoes (Aedes albopictus) can transmit the yellow fever virus. The research found that the virus can adapt to this species, which is widely present in urban and forest areas, posing a major public health threat.
A team of researchers has successfully sequenced and assembled the cane toad genome, providing a reference for understanding its interplay with ecosystems. The findings also identify three new viruses that could potentially be used as biocontrol agents, offering new hope in controlling the invasive species' population.
A viral protein, W protein, targets critical human cell function to suppress immune responses and promote fatal disease. The findings suggest potential strategies for developing therapies to block the interaction between the viral protein and host proteins.
Researchers at the Salk Institute and University of Florida used cryo-electron microscopy to image an AAV2 virus with improved resolution. The study reveals key changes in the viral portal that enable it to be less infectious, potentially informing gene therapy applications for various diseases.
Researchers analyzed brain responses of people reading real news headlines to forecast popularity among readers. Infrequent news readers were better able to predict article success, suggesting they responded more broadly to content value. The study's findings could inform Army initiatives on communication and messaging.
Researchers used fMRI data to analyze brain activity of infrequent and frequent news readers, finding that the former group was better at predicting article popularity. The study suggests that people who don't normally read the news are more representative of general population trends.
Scientists developed a model to accurately predict the transmission dynamics of various viruses, enabling optimized vaccination programs. The analysis analyzed over 100 enterovirus serotypes and demonstrated patterns in their transmission cycles.
A plant virus manipulates aphid species to its advantage by increasing the nutrients in host plants, making it easier for aphids to feed. This allows late-arriving aphids to outcompete early arriving ones, leading to boosted reproductive success and increased spread of the virus.
Researchers found that people with the rare disease have genetic mutations in CIB1, EVER1, or EVER2, which compromises their immune response to ß-HPVs. The study revealed that ß-HPVs can replicate and cause skin lesions and cancer when this defense mechanism is disrupted.
A new understanding of thawing permafrost in Sweden could improve predictions and guide efforts to slow climate damage. Scientists have identified more than 1,500 microbial genomes and 1,900 new viral populations, shedding light on the role of microbes in methane production.
Two biological control agents, myxoma and rabbit haemorrhagic disease viruses, have been found to work together to control feral rabbit populations in Australia. The study used data from the largest wild rabbit study in the world to show that both viruses are effective when acting together.
Researchers at Brigham and Women's Hospital developed a rapid, deployable, low-cost diagnostic test for Zika using mobile health technologies, targeting resource-limited settings and home testing for couples trying to conceive
Researchers have discovered the secret to the RSAD2 gene's success: an enzyme that generates a compound called ddhCTP, which sabotages viral replication by disrupting CTP conversion. This finding could form the basis for potent new antiviral drugs with a favorable safety profile.
A team of researchers has identified 27 new viruses in bees from around the world, shedding light on the impact of viral pathogens on bee health and agriculture. The discovery was made using a novel high-throughput sequencing technique that efficiently detected both known and unknown viruses.
Researchers found that cells use septins to form cage-like structures around viral particles, inhibiting their release and preventing the virus from spreading. The study provides new insights into the cellular mechanisms that control viral infections.
Researchers have discovered that giant viruses, known as pandoraviruses, can invent new genes through spontaneous mutations in intergenic regions. This suggests that these viruses may be
A new technology improves on retrograde viral tracing, enabling neuroscientists to study the connectivity of specific neurons and their functions. The 'receptor complementation' strategy eliminates tropism, a common problem in retrograde tracing, allowing for more accurate results.
A recent study has identified certain types of bacteria and viruses that are readily ejected into the atmosphere when waves break, while others are less likely to be transported. This discovery sheds new light on the potential health risks associated with breathing in ocean microbes and other biological material.
Scientists have identified a molecular handle that chikungunya virus uses to get inside cells, which could lead to ways to prevent or treat disease caused by the virus. The researchers found that blocking this handle reduces chikungunya infection and signs of arthritis.
Researchers have developed a molecule that can block multiple strains of the common cold virus from hijacking human cells. The molecule targets N-myristoyltransferase, a protein in human cells, making emergence of resistant viruses highly unlikely.
Scientists have developed a statistical framework to predict chikungunya and Zika outbreaks based on dengue fever 'hot spots'. The analysis used eight years of data from Merida, Mexico, and showed that people living in these hot spots had twice the rate of infection as those outside.
A new virus has been discovered in the waters of Oahu, Hawaii, which infects common marine algae and contains the largest genome ever sequenced for a viral infection. The virus, named TetV-1, appears to have picked up genes from its host, allowing it to survive in low-oxygen conditions.
Researchers verify anomalous amplitude apodization for non-spherical particles, boosting microscope magnifying power and peak field intensity. This technique enhances imaging capabilities for biological molecules, viruses, and living cells.
Researchers analyzed the survivability of RNA-containing viruses, discovering that inaccurate genetic copying helps them adapt to adverse conditions. The study found that viruses can repair damaged elements or evolve new properties to compensate for damage, ensuring their survival and persistence.
Research reveals that HIV-1 viruses transmitted from mother to child during delivery are more resistant to maternal antibodies than non-transmitted variants. A new vaccine aims to boost maternal antibody attack, reducing transmission risk during delivery.
Researchers at the University of Virginia Health System used a homemade microscope to reveal the structure of a cancer-causing virus's 'tether' that anchors it to our DNA. This discovery could lead to cures for viral infections like HPV and Epstein-Barr by disrupting the tether.
A study of NYC house mice reveals they carry disease-causing pathogens, including antibiotic-resistant bacteria like C. difficile and Salmonella, which can be transmitted to humans. The study also finds evidence of viruses present in mouse droppings, some of which may infect other animals.
Researchers found that IgA1 antibodies can protect against flu viruses through two mechanisms: acquired immunity and innate immunity via sialic acids. This discovery could lead to more effective flu vaccines and treatments.
The World Mosquito Program launches a self-sustaining program in La Paz, Mexico, using Wolbachia mosquitoes to provide long-lasting protection against dengue, Zika, and chikungunya viruses. The initiative aims to strengthen community resilience against emerging health threats.
A study published in Nature Microbiology reveals how reovirus hijacks the host cell's TRiC protein to assemble new viruses, shedding light on a poorly understood process. This discovery could lead to new therapeutics and contribute to understanding protein-misfolding diseases like Alzheimer's and Huntington's.
Researchers at MSU have discovered a new way viruses assemble themselves and eject DNA into host cells, with potential applications in medicine and biotechnology. The study focused on the Acidianus tailed spindle virus, which can change shape to interact with its host cells.
Researchers found that viruses use epigenetic regulation to mute the immune system, causing cancer cells to proliferate. By demethylating specific gene promoter regions, it may be possible to revive an immune system muted by cancer-causing viruses and increase the effectiveness of immune-based therapies.
A recent study reveals that almost one billion viruses and more than twenty million bacteria are deposited daily in high-mountain areas via atmospheric rain washout and gravity sedimentation. The research finds that viruses tend to adhere to smaller organic particles, while bacteria stick to mineral particles from the Sahara Desert.
Researchers at Joslin Diabetes Center discovered that four viruses can produce insulin-like hormones that bind to human insulin receptors and stimulate cellular signaling. This finding opens up a new field of study in microbial endocrinology, potentially revealing biological mechanisms behind diabetes, autoimmune disease, and cancer.
A team of researchers has mapped the biochemical networks of Aedes aegypti mosquitoes, identifying key pathways that facilitate virus replication. The study's findings have significant implications for controlling mosquito-borne diseases like dengue, Zika, and chikungunya.
A University of Iowa biologist discovered a virus family whose set of genes is similar to that of eukaryotes, helping clarify the evolution of eukaryotes after branching from prokaryotes. Giant viruses like Marseilleviridae may have been the source of these genes.