Add BrightSurf on Google Email

Gene therapy may offer a new treatment strategy for alcohol use disorder

Researchers have discovered that gene therapy may prevent relapse in patients with serious alcohol addiction by altering dopamine function in the brain's mesolimbic reward pathway. The treatment involves sustained release of glial-derived neurotrophic factor (GDNF) in a specific region of the brain.

SourceOhio State University Wexner Medical Center·JournalNature Medicine·TypeRandomized controlled/clinical trial·DateAug 14, 2023

Preying on hungry, anxious worms

In a new study, Salk Institute scientists discovered that dopamine regulates anxious worm behavior in the presence of nipping predators. The findings illuminate how this dopamine-regulated brain pathway may be related to anxiety and could provide insight into human conditions like PTSD.

SourceSalk Institute·JournaleLife·TypeExperimental study·DateJul 11, 2023

The Ising on the cake

A team of researchers from Kyoto University and international institutions has developed a mathematical solution to the temporal asymmetry of nonequilibrium disordered Ising networks. This breakthrough offers insights into the behavior of biological systems, machine learning, and AI tools.

SourceKyoto University·JournalNature Communications·TypeComputational simulation/modeling·DateJul 4, 2023

That essential morning coffee may be a placebo

Scientists found that drinking coffee increases connectivity in higher visual networks and executive control regions of the brain, leading to improved alertness and cognitive performance. In contrast, taking only caffeine did not replicate these effects, suggesting that the experience of drinking coffee plays a crucial role.

SourceFrontiers·JournalFrontiers in Behavioral Neuroscience·TypeExperimental study·DateJun 28, 2023

New study reveals brain's potential to regulate fentanyl consumption, offering hope in the fight against opioid addiction

A recent study by the Hebrew University of Jerusalem has unveiled crucial insights into the brain's ability to regulate fentanyl consumption. The research discovered that claustral neurons can modulate fentanyl intake, suggesting a potential target for intervention in fentanyl addiction.

SourceThe Hebrew University of Jerusalem·JournalCurrent Biology·TypeExperimental study·DateJun 26, 2023

Brain pathway identified that impairs postpartum social behavior after adolescent stress

A study by University of Alabama at Birmingham researcher Minae Niwa found that adolescent psychosocial stress, combined with pregnancy and delivery, causes hypofunction of a key neural circuit. This altered circuitry leads to abnormal social behavior in postpartum women, including reduced interaction time with familiar mice.

SourceUniversity of Alabama at Birmingham·JournalNature Communications·TypeExperimental study·DateJun 23, 2023

Can humor help treat depression and anxiety?

A study published in Brain and Behavior found that humor therapy reduced symptoms of depression and anxiety in participants from various countries. The analysis included 2,964 participants and nine different countries, suggesting that humor therapy may be a feasible complementary alternative for clinicians, nurses, and patients.

SourceWiley·JournalBrain and Behavior·DateJun 21, 2023

Slightly lost bumblebees use scent to find their way home

Researchers found that bumblebees use both vision and smell to navigate, with scent marks playing a crucial role in pinpointing the nest entrance in visually ambiguous situations. In experiments, bumblebees overwhelmingly focused on locations suggested by scent marks when visual landmarks were conflicting.

SourceFrontiers·JournalFrontiers in Behavioral Neuroscience·TypeExperimental study·DateJun 14, 2023

University of Ottawa team leads promising new research on devastating brain disorder

A University of Ottawa team has discovered a vital role for the VGLUT3 transporter protein in modulating the development of Huntington's disease. The study shows that blocking glutamate release through this protein can lead to an amelioration of the disease progression, offering new hope for potential treatment approaches.

SourceUniversity of Ottawa·JournalNeurobiology of Disease·TypeExperimental study·DateJun 7, 2023

Newly discovered brain mechanism linked to anxiety, OCD

Researchers at the University of Utah Health have made a groundbreaking discovery about the role of microglia in controlling anxiety-related behaviors. The study found that specific microglia populations activate anxiety behaviors while others dampen them, and these cells communicate with neurons to invoke behaviors.

SourceUniversity of Utah·JournalMolecular Psychiatry·TypeExperimental study·DateJun 5, 2023

Monkey see, monkey do: observing macaques to better understand movement synchronization

Researchers observe 'social motor entrainment' in macaques, where movements synchronize with others, and find it varies by animal pairs, social hierarchy, and stimulus type. This study provides insights into the neural underpinnings of social cohesion and has implications for understanding human conditions like autism spectrum disorder.

SourceNational Institutes of Natural Sciences·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 30, 2023

UNDER EMBARGO: Mount Sinai researchers identify potential new treatment for those who act out their dreams while sleeping

Researchers have identified a novel model and therapy to mitigate the development of REM sleep behavior disorder, which affects over 3 million Americans. Dual orexin receptor antagonists have been shown to significantly reduce dream enactment behaviors, providing a promising new treatment option.

Morning lark or night owl: Baylor researchers highlight the influence of behavior on the circadian preferences of college students

A new study from Baylor University's Sleep Neuroscience and Cognition Laboratory reveals that chronotypes can fluctuate across a semester, with evening-type students showing worse sleep quality and duration. Engaging in healthier daytime behaviors can lead to better sleep, improving daytime life and academic success.

SourceBaylor University·JournalChronobiology International·TypeData/statistical analysis·DateMay 17, 2023

Sleep phase can reduce anxiety in people with PTSD

Researchers discovered that sleep spindles can alleviate anxiety in people with post-traumatic stress disorder (PTSD), contradicting recent findings. The study found that spindle rate frequency was higher during a stressful visit than a control visit, suggesting non-invasive ways to harness the benefits of this sleep stage for symptom ...

SourceUniversity of California - San Francisco·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·DateMay 3, 2023

Emotion-focused therapy for bipolar disorder targets the amygdala

A new study found that emotion-focused therapy increased activation and connectivity of the amygdala in patients with bipolar disorder, leading to improved emotion processing. In contrast, cognitive-behavioral therapy showed increased activation of brain regions related to social function but not altered amygdala activity.

SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeRandomized controlled/clinical trial·DateApr 17, 2023

This elephant’s self-taught banana peeling offers glimpse of elephants’ broader abilities

Researchers discovered an Asian elephant named Pang Pha's exceptional banana-peeling ability, which suggests that elephants have impressive cognitive and manipulative skills. The study found that Pha learned to peel bananas through observational learning from humans, challenging the idea that such complex behaviors are unique to humans.

SourceCell Press·JournalCurrent Biology·TypeObservational study·DateApr 10, 2023

Four different autism subtypes identified in brain study

A new study from Weill Cornell Medicine has identified four clinically distinct groups of people with autism spectrum disorder, each with unique brain connection patterns and behavioral traits. The findings highlight the potential for personalized therapies tailored to individual subgroups, which may lead to more effective treatments.

SourceWeill Cornell Medicine·JournalNature Neuroscience·DateApr 7, 2023

Duke-NUS study: Early morning university classes correlate with poor sleep and academic performance

A study by Duke-NUS Medical School researchers analyzed tens of thousands of student data to determine the impact of early class start times on attendance, sleep behavior, and academic performance. The findings suggest that students who attend early morning classes often lose an hour of sleep and experience lower grades.

SourceDuke-NUS Medical School·JournalNature Human Behaviour·DateMar 27, 2023

Imaging captures social dynamics of 'pee-shy' mice

A recent study published in Communications Biology used thermal imaging to capture the social dynamics of 'pee-shy' mice, revealing that males adjust their urine marking behavior based on their past interactions. The research provides insight into how animals manage their social signaling, a crucial aspect of their survival and evolution.

SourceCornell University·JournalCommunications Biology·DateMar 22, 2023

Preterm babies do not habituate to repeated pain

A study found that preterm infants do not habituate to repeated pain, unlike full-term infants. This lack of adaptation may affect their brain development and increase vulnerability to pain. The researchers' findings suggest that the ability to adapt to pain might develop during the third trimester of pregnancy.

SourceUniversity College London·JournalCurrent Biology·TypeExperimental study·DateMar 16, 2023

COVID-19 can cause 'face blindness'

A Dartmouth study found that COVID-19 can cause 'prosopagnosia,' or face blindness, and impairments in navigational abilities. Researchers worked with a patient who experienced difficulty recognizing faces and navigating, leading to dissociation between face recognition and cognitive map representation.

SourceDartmouth College·JournalCortex·TypeCase study·DateMar 13, 2023

How fruit flies feast for pleasure as well as necessity

Researchers discovered that fruit flies have distinct hunger drives, one driven by need and the other by pleasure, which arise from unique neural mechanisms. The study found that hungry flies increase feeding event duration and total events, and identified specific brain regions activated by pleasurable food environments.

SourceeLife·JournaleLife·DateMar 7, 2023