Research on the brain basis of behavior. Covers reward and pleasure signals, attention in children, taste circuitry, and adaptive AI models.
Researchers have found that honeybees use linear landscape elements, such as irrigation channels, to guide their search flights when looking for their hive in new areas. The bees retain a navigational memory of their home area based on these elements, which they generalize to the new area to find their way home.
A new UC Davis study has identified 194 significantly different genes in the brains of people with autism, with many linked to brain connectivity, immune response, and inflammation. The research also found age-dependent differences in genes related to synaptic function and cell loss.
Researchers have found that long-tailed macaques reject inferior rewards more frequently when provided by a human than an automatic feeder, indicating social disappointment. This behavioral pattern is consistent with frustration towards the experimenter's decision, rather than a comparison of rewards with conspecifics.
The Janelia FlyLight Project Team has released over 74,000 images of fruit fly brain neurons, generated from more than 5,000 different genetically modified fly strains. These images are now freely available for scientists to quickly and easily find the neurons they need to test theories about the nervous system.
Children with autism may not process visual illusions in the same way as their peers, indicating a potential issue with predicting and filling in missing visual information. This finding has implications for understanding and supporting individuals on the autism spectrum.
Researchers discovered a new brain pathway that expresses corticotropin-releasing hormone, controlling responses to stress, which disrupts reward behaviors in mice. This discovery offers a new therapeutic target for treating mental illness, particularly depression, substance abuse, and excessive risk-taking.
A study of 232 healthy adults found that hypnosis and mindfulness meditation reduced pain intensity and tolerance, while prayer did not. The results suggest that brief sessions of these techniques may be useful for acute pain self-management.
Researchers at Texas A&M University School of Medicine have identified a specific brain circuit that characterizes how fentanyl affects the brain. Suppressing negative emotional states may increase a person's chance of overcoming opioid use disorder.
Researchers identified apremilast as an incredibly promising treatment for alcohol use disorder, reducing consumption by more than half in a clinical trial. The medication, approved for psoriasis and psoriatic arthritis, triggers increased activity in the brain's nucleus accumbens to control alcohol intake.
Researchers found that rats adopt a non-greedy strategy to balance speed and accuracy, sacrificing immediate rewards for improved learning outcomes. The study suggests that slower reaction times lead to faster learning and higher rewards in both experimental and simulated environments.
A study in mice found that chronic stress impairs allopregnanolone production, a key neurosteroid involved in regulating emotions. This finding suggests that synthetic neurosteroid analogs might exert a beneficial effect in individuals with depression.
Researchers from New York Institute of Technology have made significant findings on how the sense of smell is impacted in individuals with autism. The study analyzed a mouse model of autism and found that scent processing was impaired at a later step, after signals were processed at the olfactory bulb input.
A team of researchers at MUSC discovered a neural circuit that inhibits motivated behaviors, which can prevent reward-seeking behavior in high-risk contexts. Administering opioids causes immediate disruption of this circuit, leading to even riskier behaviors.
Researchers at Technische Universität Berlin demonstrated that fish schools operate at criticality, a state of optimal alertness similar to the brain. This allows them to process external stimuli and transmit information over long distances, enabling coordinated responses.
Researchers propose using brain scans to measure similarity in trademark cases, reducing inconsistencies and bias. This approach provides a reliable method for determining similarity without relying on subjective surveys or expert opinions.
A UTHealth Houston study found caregivers of people at high risk of CTE are more likely to seek information from social media than physicians. The study also showed that participants reported 77% of online CTE information is probably true, with league-sponsored websites and healthcare providers being the least credible sources.
Researchers at the University of Calgary discovered a reduction in brain function's brake signal contributes to decisions about eating in obese mice. The study found that when this region is disabled, lean mice continue to overeat despite feeling full.
A study at Nagoya University found that specific neurons in fruit flies process and distinguish between different courtship songs, differing between species. The researchers used calcium imaging to determine how these neurons respond to different courtship songs, finding that the responses varied between species.
Researchers have identified a full pathway from skin neurons to brain pleasure centers, revealing the neurobiological basis of pleasurable social touch. The study suggests that touch-based therapies may alleviate anxiety, stress, and depression, with potential applications for autism and other conditions.
A study by Alexandra Rosati and colleagues found that adolescent chimpanzees share risk-taking behaviors with human teens, but tend to be less impulsive. In tests involving food rewards, adolescent chimpanzees chose the riskier option more often than adults, but showed similar negative reactions to disappointing outcomes.
Osaka Metropolitan University scientists discovered that visual food cues influence eating behavior even when participants are unaware of them. Neural activity in the brain's frontal lobe differs depending on whether images are presented consciously or unconsciously, suggesting a role for unconscious processes in controlling eating beh...
Researchers have identified a new genetic pathway involved in regulating sleep from fruit flies to humans. The Pig-Q gene is associated with sleep regulation in both humans and animals, providing a novel insight into the genetics of insomnia.
Researchers found no correlation between daily mood and confidence markers, but mood-related states and confidence level fluctuated at different time scales. Mood changes occurred faster than confidence level changes.
A new paper in Nature Reviews Disease Primers provides a global overview of hazardous drinking and alcohol use disorders, highlighting current approaches to diagnosis, screening, prevention, management, and treatment. The study emphasizes the need for further research, particularly on adolescents and effective behavioral interventions.
Researchers discovered a neural system for self-localization in larval zebrafish using whole-brain functional imaging. The multiregional hindbrain circuit integrates visual information to form a memory of past displacements, correcting for accumulated displacements over many seconds.
Neuroscientists have uncovered a brain circuit that enables mice to rapidly escape to shelter when faced with a threat. The retrosplenial cortex and superior colliculus form a circuit that encodes the direction to a shelter, allowing mice to accurately orient and escape.
Research from University of Virginia Health System suggests antidepressants can heighten lifelong brain changes in babies, such as autism, when combined with infection or inflammation during pregnancy. SSRIs interact powerfully with the mother's body, causing harmful changes in the placenta and developing brain.
Researchers discovered that eye movements can reveal valuable information about how humans make decisions. The study found that the speed and vigor of eye movements increased as participants considered their options before making a choice.
A new Lancet Viewpoint provides recommendations for providers and parents to detect and intervene in adolescent substance use. The study highlights the challenges of detecting substances with 'invisible symptoms' and emphasizes the importance of open communication and well-validated screening tools.
A new study has shed light on how the most commonly used ADHD medication, methylphenidate, works in the brain. The research found that methylphenidate increases dopamine levels in the nucleus accumbens and improves coordinated brain network activity, resulting in more stable sustained attention in children with ADHD.
Researchers at Florida State University have found that aspartame, a common artificial sweetener, can cause anxiety-like behavior in mice. The study, published in the Proceedings of the National Academy of Sciences, suggests that aspartame's effects extend up to two generations from exposure, affecting male mice and their offspring.
Researchers discovered that trauma changes brain mechanisms involved in learning and survival, such as the salience network. The study found that people with PTSD struggle to distinguish between safe and dangerous stimuli when emotions are involved.
Researchers identified surprising differences in TGF-β genes across nine nematode species, revealing unexpected changes in function between species. This study provides new insights into the evolution of TGF-β signaling pathways and their impact on development, behavior, and disease in humans and parasites.
A recent study published in Journal of Clinical Psychiatry found that only about 10% of children and adolescents who didn't improve with cognitive behavioral therapy opted for medication treatment. Patient characteristics, such as racial and ethnic minorities, younger patients, and expectations of treatment effectiveness, were identifi...
The study found conserved structures of neuronal activity in the sensorimotor cortex of freely moving rats, revealing a clear gradient for contralateral bias. This breakthrough helps understand brain control of movements under natural conditions and enables further development of neuroprosthetic devices.
A new paper by researchers at the University of Birmingham argues that a 'one size fits all' approach to treating early psychosis may not be effective. Instead, they propose using machine learning techniques to deliver tailored treatment plans that address individual needs and improve outcomes.
Researchers discovered that synchronized neural oscillations in the right hemisphere of the brain induce empathic behavior in mice, allowing them to perceive and share each other's fear. The study identified the causal relationship between 5-7 Hz oscillations in the cingulo-amygdala circuit and empathic responses.
A new study published in Molecular Psychiatry sheds light on the neural mechanisms underlying stress-related behaviors, revealing that glutamate cells in the ventral tegmental area play a critical role. The research found that mice exposed to uncontrollable stressors exhibited more pronounced anxiety-like behavior, whereas those with c...
A new study reveals ketamine dramatically changes neuronal activity patterns in the cerebral cortex, turning off active neurons and turning on silent ones. This switch in brain activity may impact our understanding of ketamine's antidepressant effects and future research in neuropsychiatry.
Researchers created a miniature microscope that can image neural activity on a single-cell level from all cortical layers without interfering with animal behavior. The tool, developed by the Max Planck Institute for Neurobiology of Behavior, allows scientists to study how brain cells respond to environmental light and visual cues durin...
A Collaborative Research Centre investigates animal navigation using the Earth's magnetic field. The study focuses on vertebrates, including birds and fish, aiming to protect endangered migratory species.
Scientists at Texas A&M University found that transplanting intestinal epithelial stem cells can repair the gut and reduce inflammation, potentially preserving cognitive function after a stroke. The study suggests that targeting gut health may be key to developing more effective stroke therapies.
A Scripps Research team has identified a class of drugs that may break the link between post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD). The findings show that these compounds, which target brain pathways shared by both disorders, can reduce alcohol preference and other behaviors associated with PTSD.
A new study explores how corporal punishment impacts neural systems, linking it to increased anxiety, depression, and altered brain activity. The research found that adolescents who experienced physical punishments showed a larger neural response to error and a blunted response to reward.
A study published in Current Biology found that children exhibit rapid boosts of GABA during visual training, stabilizing new learning and making it more efficient. This discovery suggests that children may acquire new knowledge and skills faster than adults, with implications for teaching and learning strategies.
Researchers have developed a videography-based method to track skeletal kinematics in freely moving rodents, providing insights into animal behavior and brain function. The approach uses an anatomically grounded skeleton model and can be applied to multiple furry species.
Researchers at USC found significant differences in gray matter density between boys and girls with binge eating disorder, suggesting unique brain structures and potentially different treatments. The study underscores the need to include males in future research on eating disorders.
Recent studies have shed light on the biological mechanisms that connect sleep and anxiety, highlighting the importance of sleep in regulating stress responses. Research has shown that inadequate sleep can lead to increased anxiety and stress, while also exacerbating mental distress.
A study published in The EMBO Journal reveals that the anterior cingulate cortex is activated in female mice acquiring maternal behavior through repeated experience with pups. This discovery provides a potential basis for developing therapeutic options for postpartum depression and other conditions disrupting mother-child bonding.
Researchers from Tokyo University of Science found that chronic social defeat stress (cSDS) induced mice showed higher intestinal transit ratio and visceral pain-related behaviors, similar to IBS. The study suggests that prolonged psychological stress can cause IBS-like symptoms in mice without intestinal lesions.
Researchers used simulations of zebrafish brain, environment, and spatially-varying swimming behavior to conclude that fish look down to understand their surroundings' motion. This adaptive behavior helps fish avoid being swept away by turbulent water.
Dr. Michael Yartsev was selected as the 2022 Peter Gruss Young Investigator Award winner for his groundbreaking research on naturalistic behavior in bats. His work has made a significant impact on the scientific community, inspiring young scientists and promoting cooperation.
Research reveals that common gut bacteria enhance cocaine effects in mice by consuming glycine, leading to behavior abnormalities. Supplementing glycine or using a genetically modified bacteria reduces response to cocaine, demonstrating its role as an addiction mediator.
Scientists have created an extensive new map of the brain's olfactory circuits, revealing a complex system that processes different aspects of odor information. The map suggests the existence of parallel neural circuits dedicated to assessing smell identity, pleasantness, and origin, offering new insights into olfactory processing.
A new study by Pitt mathematicians uses math borrowed from neuroscience to describe how swarms of synchronous fireflies coordinate their light show. The researchers found that varying distances between fireflies affects the resulting blinks, producing patterns like ripples or spirals.
Researchers found that the brain's defense system is activated during selfless helping behavior, contrary to the long-held idea that empathy drives such actions. The study used fMRI scans to measure brain activity in 49 healthy volunteers who were asked to decide whether to help another person avoid discomfort.
Researchers at HSE University used transcranial magnetic stimulation to suppress brain activity in the dorsolateral prefrontal cortex, leading to test subjects making less rational decisions. The study provides insight into the mechanisms behind gaming addiction and offers a potential new approach to understanding risky choice.
A Cornell University researcher is using optical microscopy and other tools to map the brain's neural response to psychedelics. The study aims to develop fast-acting antidepressants and treatments for substance-use disorders and cluster headaches.
A team of researchers has identified specific neurons in the amygdala that drive mice to eat fatty or sugary foods, even when not hungry. Switching off these neurons reduced overeating and protected against obesity, while also boosting physical activity and improving metabolic health.
The study reveals that a genetic mutation can accelerate the body's internal clock, leading to improved adjustment to shift work schedules. The findings have implications for understanding the health consequences of circadian misalignment and developing medical treatments.