A new study by neuroscientists at MIT's Picower Institute finds that the anterior cingulate cortex (ACC) and motor cortex collaborate to update understanding and behavior when a task requires more steps. The ACC helps M2 adjust to new rules, but reduced activity leads to increased negative outcome encoding cells' activity in M2.
Researchers will design and distribute two new types of miniscopes, enabling deeper brain observations. The devices will be light enough for rodents, unlocking insights into neurological disorders like Alzheimer's disease.
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Ben-Gurion University researchers Dr. Moti Salti and Dr. Dafna Bergerbest propose a framework to objectively compare subjective experiences and reveal their neuronal basis. They focus on numerosity as a field where objective criteria can be established, aiming to map individual transfer-functions at both behavioral and neuronal levels.
A large-scale study led by the University of Leicester found that people with a strong sense of fairness cheat less, regardless of winning or losing. The researchers examined the behavior of over 500 participants in lab-based games and discovered that only those with low 'inequality aversion' were more likely to cheat.
A study published in NeuroReport reveals that ultrasound exposure improves depressive behavior in a rat model of depression. OB rats exposed to USV had significantly lower hyperemotionality scores and plasma corticosterone levels than unexposed rats, suggesting potential anti-depressant effects.
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Researchers found that the brain's cortex uses principles of calculus to implement a 'stop' signal, allowing for quick and precise decision-making in goal-directed behaviors. The study reveals how the brain integrates learned rules with sensory information to guide actions.
Researchers discovered that communication between two brain regions, parietal cortex and premotor cortex, is co-dependent on instantaneous timescales to represent and maintain working memory. This finding challenges previous understanding of working memory representation in the brain.
Researchers found that a higher voice pitch leads to faces being assessed as half a year younger on average. However, the face itself provides crucial information for evaluating attractiveness, femininity, and health, making the voice less influential in these evaluations.
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A new study finds that racial discrimination affects brain microstructure, increasing the risk for health disorders in Black women. Traumatic experiences lead to changes in brain white matter tracts, which may enhance risk for negative health outcomes.
Researchers found that children with autism process brain waves differently when focused on body movements versus colors, highlighting a key challenge in communication.
Researchers at City University of Hong Kong have identified the key mechanism behind roundworms' precise bowel movements, revealing a synchronized nerve impulse between the brain and gut. The study found that the AVL nerve cell in the head regulates the defecation rhythm by relaying and modulating pacemaker signals from the gut.
Researchers uncover brain area responsible for driving action and suppressing drive in a novel task designed to study active action suppression. The team identified the dorsomedial striatum as the key region promoting action, while the indirect pathway suppresses it, leading to an 'impulsivity switch'.
Researchers discovered that hippocampal place cells represent direction and distance to a goal in addition to current location. A vector field provides signal towards the goal, aiding flexible navigation.
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A recent study published in Nature has identified a complex neural network in the fruit-fly brain that shapes behavior and decision-making, particularly when it comes to food choice. The 'appetite map' created by the researchers reveals how internal states, such as nutrient deficiencies and pregnancy, interact to guide behavior.
A new theory suggests that lack of perceived safety in marginalized communities can have a direct impact on physical and mental health. This concept challenges decades-old thinking that minority stress is the primary cause of health disparities in the LGBTQ community.
Research reveals that brain responses to stories change dramatically between childhood and adulthood, with different brain regions activated in each age group. Children as young as seven show similar patterns of brain activity to adults when watching a story, but their brains are less synchronized and more focused on sensory details.
Researchers argue that neurons proactively trigger influx of needed substances to survive, creating a systemwide group of metabolically cooperating cells. This principle is central to learning, driving human behavior. The study aims to explore tumour cell responses to individual behaviors and develop new cancer treatments.
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Researchers discovered that blocking certain acetylcholine receptors in the lateral habenula balances reward and aversion, making it harder to resist seeking cocaine. This finding identifies a new role for these receptors as a potential target for treating cocaine use disorder.
Researchers propose a new framework for understanding how our prefrontal cortex makes decisions, highlighting the role of ventromedial prefrontal cortex in assigning value to options and medial prefrontal cortex in confidence and deliberation. The study's findings can be generalized to other types of behavior, such as judgments.
A study from Japan's University of Tokyo reveals that users can form a strong sense of ownership with virtual robotic arms, expanding their perceived personal space. The research aims to inform the design of real-life supernumerary robotic limb systems that people can use naturally.
Researchers elucidated the molecular mechanisms of acetylcholine in learning and memory, revealing a signaling cascade involving protein kinase C. The study opens doors to new therapeutic strategies for Alzheimer's disease.
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Scientists identify PiT2-loop7 missense mutations causing inorganic phosphate dyshomeostasis, leading to primary familial brain calcification. The study reveals how these mutations affect PiT2 phosphorylation and membrane localization, reducing Pi transport activity.
Researchers found that walking enhances performance on cognitive tasks in 14 participants by increasing frontal brain function, while 12 others showed no improvement. This discovery highlights the flexibility of a healthy brain and has implications for understanding aging and neurological disorders.
A new study by an international group of researchers has found substantial reductions in grey matter in people with anorexia nervosa, a condition characterized by severe food restriction and low body weight. Early intervention and treatment can help the brain repair itself, according to the research team led by Dr. Paul M. Thompson.
Researchers analyzed data from 599 patients with premenstrual dysphoric disorder and found that 34% have attempted suicide, with high rates of suicidal ideation, planning, and self-injury among women. The study highlights the need for accurate diagnosis and screening of suicidal ideation in patients with PMDD.
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Women with self-injury behaviour show a more effective pain-modulation system, displaying more connections between pain perception and modulation brain areas. This finding suggests that effective pain modulation is a risk factor for self-injury behaviour, providing valuable insights for improving treatment and support.
Researchers at the Sainsbury Wellcome Centre discovered that brain area communication is dynamic and changes over rapid timespans, with influences varying on a fast timescale. This finding suggests that cortical areas may control different aspects of processing in downstream regions over very short time spans.
A new study reveals that drumming can improve the life quality of young people diagnosed with autism by enhancing brain function and behavior. Participants showed fewer signs of hyperactivity, inattention, and repetitive behaviors, demonstrating better control of their emotions.
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A new study published in Nature reveals that a small population of neurons near the base of the brain can induce symptoms of sickness, including fever, appetite loss, and warm seeking behavior. The researchers found these neurons have receptors capable of directly detecting molecular signals from the immune system.
Researchers discovered two novel categories of cells in the BLA that respond to ethological stimuli, including event-specific neurons responding to one type of stimulus and panresponsive neurons responding equally well to multiple stimuli. These findings suggest a larger role for the BLA in memory and behavior.
Research found that stimulating a specific brain circuit relieves pain and reduces defensive behaviors in rats, indicating potential physical and psychological relief. The pathway also increases reward and feeding behavior, suggesting improved emotional state.
Neuroscientists demonstrate that mice can learn to suppress their innate escape response, effectively ignoring stimuli deemed non-threatening. The study's findings show that this suppression is specific to the stimulus and dependent on recent threat-escape history.
A new study reveals that combinations of multiple genetic factors determine the risk and severity of symptoms in Autism Spectrum Disorder. Researchers analyzed 37,375 individuals from 11,213 families to understand how rare mutations and common genetic variation contribute to ASD.
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Kessler Foundation researchers use signal detection theory to characterize cognitive fatigue in multiple sclerosis. The study reveals an association between subjective 'state' fatigue, response bias, and brain activation patterns in both MS and control groups. This finding supports the use of signal detection metrics as an objective me...
A recent study out of the Complexity Science Hub Vienna developed a mathematical and computational framework for analysing neural activity in C. elegans, a tiny worm used to study neural activity. The study proposes a way to unmask the roles of neurons by using more natural perturbations.
Researchers at Sainsbury Wellcome Centre found that mice can choose the best escape route after only 10 minutes of exploration, without needing to experience threat. The study suggests that mice use innate heuristics and natural exploration to learn this information.
Researchers at West Virginia University are studying the mechanisms behind Alzheimer's disease and PTSD, using animal models to investigate how stressful events affect brain cells. They aim to understand the role of estrogen and high-cholesterol diet in developing the disease.
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A study in a mouse model found that viral infections during pregnancy can affect the mother's brain and disrupt maternal care behavior after birth. The research team identified structural, molecular, and functional changes in the brains of mothers with viral-like immune activation.
Researchers found that children with a history of maltreatment exhibited an early maturation of the immune system, similar to adolescents. This study suggests that secretory immunoglobulin A could be a biomarker for acute stress in young populations.
Researchers at EPFL's School of Life Sciences create a digital twin of Drosophila called NeuroMechFly, which uses biomechanical modeling and machine learning to simulate the fly's movements. The model is validated through experiments that demonstrate its accuracy in replicating real animal behaviors.
Researchers used worms to study how hunger signals in the gut communicate with the brain, leading to riskier behavior. The findings suggest that proteins in intestinal cells move dynamically to transmit signals about hunger, driving worms to cross toxic barriers.
Researchers found that fruit bats use echolocation during the day despite having excellent vision, suggesting a combination of both senses for enhanced navigation. This study highlights the importance of integrating different senses, like humans using visual and auditory information when crossing streets.
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The University of Texas at El Paso has received a $5M NIH grant to build an imaging and behavioral neuroscience facility focused on addressing Hispanic health disparities. The new facility will enable researchers to study the mechanisms contributing to cancer and neurological disorders in Hispanic populations.
Research using Adolescent Brain Cognitive Development study data found that urban environments with socioeconomic challenges increase psychotic-like experiences in pre-adolescent children. Early prevention is crucial as these exposures are already present in late childhood.
Researchers at Tokyo University of Science identify brain regions and signaling pathways involved in fear extinction via delta receptor activation. The study suggests a potential therapeutic agent for post-traumatic stress disorders by suppressing fearful memories.
Researchers are studying moths to understand agile decision-making in complex environments, aiming to develop autonomous bio-inspired systems. Meanwhile, a team is exploring origami- and kirigami-inspired flexible structures for multifunctional applications.
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A new study found that the release of oxytocin is linked to increased kindness and life satisfaction, with participants showing more generous behavior and empathy as they aged. The findings support religious philosophies on the importance of helping others in enhancing life satisfaction.
A study published in Current Biology found that consuming non-essential amino acids can curb appetite and encourage physical activity in mice. This mechanism is thought to be rooted in evolutionary history, where eating these amino acids promoted the urge to seek out more nutrient-rich food sources.
A recent study by NYU researchers reveals that our eyes stay focused on what we reach for due to a complex neurological process called gaze anchoring. By inhibiting eye movements, neurons in the brain enhance accuracy when grasping objects.
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Researchers found a clear link between elevated amyloid beta levels and the development of anxiety and apathy in Alzheimer's patients. These symptoms occur mainly due to underlying brain changes, not psychological reactions. The study suggests that psychiatric symptoms could be used as alternative outcome measures in treatment trials.
A study by Tokyo University of Science researchers has demonstrated that a computationally-light model can simulate complex brain cell responses, including periodic and quasi-periodic responses. The Izhikevich neuron model was found to be capable of reproducing both types of responses at lower computational cost.
Researchers found that rhesus macaques with more grooming partners had larger brain areas for social decision-making and empathy, specifically the mid–superior temporal sulcus (STS) and ventral-dysgranular insula. The study suggests that social connections influence brain structure in nonhuman primates, with possible implications for h...
A new study by UC San Francisco and Imperial College London found that psilocybin therapy reduces connections within brain areas tightly connected in depression, while increasing connections to other regions. This leads to improved depressive symptoms and better cognitive functioning in participants.
A study by Tokyo University of Science researchers used WCNs with increasing n values to find features of language that cannot be analyzed using existing WCNs. They found important features in networks with more than three co-occurrences, independent of text data.
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Researchers have developed a new MRI technique that captures the brain's function during normal behavior, revealing its activities on a scale previously unknown. This 'time-lapse' imaging method, called manganese-enhanced MRI (MEMRI), uses manganese as a contrast agent to highlight brain cell activity and neural projections.
A kindness training program adapted from Children's Kindness Network improves both parents' resilience and children's empathy. The study found that teaching kindness at home boosts parental resilience and enhances emotional intelligence in preschoolers, supporting overall brain health.
A new study published in Memory & Cognition found that eyewitnesses do not systematically bias towards selecting people with threatening facial characteristics or muscular bodies. However, participants showed highest identification accuracy for the most threatening body stimuli high in musculature.
A global survey found that podcast listeners tend to be more open-minded and intellectually curious than non-listeners. The study aimed to understand motivations and outcomes of podcast listening, revealing positive effects on mental health and well-being.
Scientists at Johannes Gutenberg University discovered that fruit fly eyes can distinguish six types of global motion patterns generated by self-motion. The T4/T5 cell subtypes directly represent complex motion cues rather than uniform directions, matching the fly's actual behavior closely.
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Neurobiologist Marion Silies is investigating how various visual systems adapt to specific environments and behavioral conditions. She will use fruit flies as an animal model to understand visual processing mechanisms and their adaptation to differing conditions.