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Signal detection theory may be useful for characterizing cognitive fatigue in multiple sclerosis

Kessler Foundation researchers use signal detection theory to characterize cognitive fatigue in multiple sclerosis. The study reveals an association between subjective 'state' fatigue, response bias, and brain activation patterns in both MS and control groups. This finding supports the use of signal detection metrics as an objective me...

SourceKessler Foundation·JournalFrontiers in Behavioral Neuroscience·TypeExperimental study·DateMay 31, 2022

New insights into the complexity of the brain

A recent study out of the Complexity Science Hub Vienna developed a mathematical and computational framework for analysing neural activity in C. elegans, a tiny worm used to study neural activity. The study proposes a way to unmask the roles of neurons by using more natural perturbations.

SourceComplexity Science Hub·JournalPLOS Computational Biology·TypeComputational simulation/modeling·DateMay 27, 2022

Why hungry worms take risks

Researchers used worms to study how hunger signals in the gut communicate with the brain, leading to riskier behavior. The findings suggest that proteins in intestinal cells move dynamically to transmit signals about hunger, driving worms to cross toxic barriers.

SourceSalk Institute·JournalPLOS Genetics·TypeExperimental study·DateMay 5, 2022

Where the mind is without fear: Scientists discover mechanism behind the chemically induced suppression of fearful memories

Researchers at Tokyo University of Science identify brain regions and signaling pathways involved in fear extinction via delta receptor activation. The study suggests a potential therapeutic agent for post-traumatic stress disorders by suppressing fearful memories.

SourceTokyo University of Science·JournalFrontiers in Behavioral Neuroscience·TypeExperimental study·DateApr 25, 2022

Ubiquitous nutrients suppress appetite and promote movement

A study published in Current Biology found that consuming non-essential amino acids can curb appetite and encourage physical activity in mice. This mechanism is thought to be rooted in evolutionary history, where eating these amino acids promoted the urge to seek out more nutrient-rich food sources.

SourceETH Zurich·JournalCurrent Biology·DateApr 20, 2022

Psychiatric symptoms in Alzheimer´s disease

Researchers found a clear link between elevated amyloid beta levels and the development of anxiety and apathy in Alzheimer's patients. These symptoms occur mainly due to underlying brain changes, not psychological reactions. The study suggests that psychiatric symptoms could be used as alternative outcome measures in treatment trials.

SourceLund University·JournalBiological Psychiatry·DateApr 19, 2022

The power of kindness in improving brain health

A kindness training program adapted from Children's Kindness Network improves both parents' resilience and children's empathy. The study found that teaching kindness at home boosts parental resilience and enhances emotional intelligence in preschoolers, supporting overall brain health.

SourceCenter for BrainHealth·JournalFrontiers in Psychology·TypeRandomized controlled/clinical trial·DateApr 11, 2022

Think piece

Researchers have developed a new MRI technique that captures the brain's function during normal behavior, revealing its activities on a scale previously unknown. This 'time-lapse' imaging method, called manganese-enhanced MRI (MEMRI), uses manganese as a contrast agent to highlight brain cell activity and neural projections.

SourceUniversity of New Mexico Health Sciences Center·JournalNMR in Biomedicine·TypeExperimental study·DateApr 11, 2022

Fruit flies adapt activity to “white nights”

Research team at University of Münster finds that a specific gene variant allows fruit flies to synchronize their circadian rhythm with temperature cycles under constant light. This adaptation enables better mating opportunities and increases the allele's evolutionary success.

SourceUniversity of Münster·JournalNature Communications·TypeExperimental study·DateMar 31, 2022

Where we grow up influences our sense of direction

Research reveals that people who grew up in rural areas have a better sense of direction than those in cities, especially in countries with complex topographies. The study used video game data from Sea Hero Quest to analyze over 400,000 participants from 38 countries.

SourceCNRS·JournalNature·TypeExperimental study·DateMar 30, 2022

Layover or nonstop? UCLA Health research says unique pattern of connectivity lets highly creative people’s brains take road less traveled to their destination

A study led by UCLA Health scientists finds that highly creative people's brains exhibit an atypical approach to connectivity, enabling them to bypass traditional hubs and form distant connections. This 'road less traveled' pattern is more efficient for creative thinking but may not be optimal in all situations.

SourceUniversity of California - Los Angeles Health Sciences·JournalPsychology of Aesthetics Creativity and the Arts·TypeExperimental study·DateMar 28, 2022

Mom’s protective behaviors run deep

Researchers at Cold Spring Harbor Laboratory have discovered that the brain region responsible for social behavior, the locus coeruleus, is activated precisely when a mother retrieves her pup. This finding could help reveal causes of disorders such as depression, anxiety, and autism, leading to potential new treatments.

SourceCold Spring Harbor Laboratory·JournalJNeurosci·DateMar 24, 2022

Duke scientists find brain network that makes mice mingle

Researchers at Duke University found a collection of coordinated brain regions that predict and direct social behavior in mice. By analyzing the electrical activity of these regions, they identified how social or solitary an individual mouse is and were able to prompt them to be more gregarious. This study may lead to better diagnostic...

SourceDuke University·JournalNeuron·TypeExperimental study·DateMar 15, 2022

For the first time: researchers identified brain wounds in IDF veterans with PTSD and relieved their symptoms using hyperbaric oxygen therapy

Researchers from Tel Aviv University found that hyperbaric oxygen therapy (HBOT) relieves PTSD symptoms in treatment-resistant veterans, improving brain function and microstructure. The breakthrough study provides new hope for PTSD sufferers, offering an objective diagnostic tool and potential long-term improvements.

SourceTel-Aviv University·JournalPLOS ONE·DateFeb 23, 2022

Rats can estimate their timing accuracy

Researchers developed behavioral task for rats to press lever within 3.2 seconds, earning rewards based on accuracy. Rats chose correct feeder based on temporal error, showing 'error monitoring' ability.

SourceCNRS·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 22, 2022

Alcohol use linked to lower connectivity in brain areas that process emotions

Researchers found lower functional connectivity between brain areas involved in social and emotional processing in individuals at risk of developing alcohol use disorder. This impairment may affect their ability to interpret facial expressions and respond to their environment, increasing the likelihood of disordered drinking.

SourceUniversity of California - San Diego·JournalAlcoholism Clinical and Experimental Research·DateFeb 8, 2022

A yet unknown neural mechanism of habit formation identified

A study by the Netherlands Institute for Neuroscience has identified a new neural mechanism of habit formation, showing that striatal dopamine signals are region-specific and temporally stable across action-sequence habit formation. This finding challenges traditional theories on dopamine signaling in habit development.

SourceNetherlands Institute for Neuroscience - KNAW·JournalCurrent Biology·TypeExperimental study·DateFeb 7, 2022

Reinterpreting our brain's body maps

A study by Professor Kazumichi Matsumiya from Tohoku University's Graduate School of Information Sciences has discovered separate body maps for different motor systems. This finding can contribute to the development of new diagnostic techniques and rehabilitation strategies for patients with motor dysfunctions.

SourceTohoku University·JournalProceedings of the National Academy of Sciences·DateJan 20, 2022

When people “Click” they respond faster to each other

A Dartmouth study found that people who respond faster to each other in conversations feel more connected. The research, published in the Proceedings of the National Academy of Sciences, used response time data to measure social connection between strangers and close friends.

SourceDartmouth College·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateJan 19, 2022