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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Does estrogen influence alcohol use disorder?

A recent study published in the Journal of Neuroscience found that high estrogen levels may increase feelings of reward in response to alcohol in female mice. The research suggests that treatment for alcohol use disorder may be more effective if sex differences are considered.

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A child's brain activity reveals their memory ability

Researchers analyzed child brain activity using fMRI to predict working memory abilities during development. The study found that brain network activity in the frontoparietal network was unique to working memory and reflected individual capabilities.

Observing the freely behaving brain in action

Researchers at Max-Planck-Gesellschaft have created a miniature microscope that can capture neural activity in all cortical layers of freely behaving rats. This breakthrough technology allows for continuous imaging of neuron populations, even during complex behaviors, providing insights into the brain's circuit dynamics.

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Using self-nudging to make better choices

Researchers describe four categories of self-nudging tools: reminders and prompts, framing decisions in a certain way, reducing accessibility of harmful options, and using social pressure. This behavioral science technique can help individuals negotiate internal conflicts and reach long-term goals.

How synaptic changes translate to behavior changes

Scientists discovered widespread synaptic changes in sea slugs that learn to reject non-food objects, offering insight into human learning's impact on the brain. The study found that synaptic modifications occur in concert across various brain areas.

New insight on maternal infections and neurodevelopmental disorders

Researchers from University of California, Davis, found that immune responses before pregnancy can predict behavioral deficits in offspring if the mother's immune system is activated during pregnancy. The study used a mouse model to identify baseline immunoreactivity as a predictor of resilience or susceptibility to immune activation.

Eyes send an unexpected signal to the brain

A subset of retinal neurons sends inhibitory signals to the brain, affecting subconscious behaviors such as synchronizing circadian rhythms with light/dark cycles. This discovery sheds light on how eyes influence our behavior and vision in response to light intensity.

Rat spinal cords control neural function in biobots

Researchers successfully combined rat spinal cords with tissue-engineered muscles, creating a biohybrid system that produces electrical activity causing contraction. This innovation could lead to breakthroughs in understanding diseases like Lou Gehrig's and developing new surgical training tools.

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Brain discovery suggests source of lifelong behavioral issues

Researchers at the University of Virginia Health System have made a groundbreaking discovery suggesting that improper cellular cleanup during brain development may cause lifelong behavioral issues. This process, mediated by the AIM2 inflammasome, plays a critical role in ensuring proper brain assembly and function.

McGill researchers identify correlation between MBI and Alzheimer's

A recent study published in Alzheimer's & Dementia found a strong association between mild behavioral impairment (MBI) and amyloid plaque deposits in the brains of elderly individuals. MBI may potentially serve as an early indicator of Alzheimer's disease, allowing for earlier diagnosis and intervention.

Changes in brain attention may underlie autism

Research suggests that individuals with autism spectrum disorder exhibit differences in attention regulation, which may be attributed to altered locus coeruleus activity. This study found that participants with autism displayed atypically smaller pupil dilations during a distraction task, indicating dysregulation in the brainstem.

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Unlocking animal behavior through motion

Researchers use physics and technology to track animal movement, revealing key findings on flock behavior, neural network tracking, and burrowing forces. By analyzing animal motion, scientists gain a deeper understanding of collective behavior and individual animal actions.

How many gender subtypes exist in the brain?

Researchers at McGill University have discovered at least nine directions of brain-gender variation using a unique dataset and machine learning algorithms. This finding has important consequences for promoting equity, diversity, and inclusion in Canada and beyond.

Fruit flies respond to rapid changes in the visual environment

Researchers at Johannes Gutenberg University discovered a mechanism employed by fruit flies to broaden our understanding of visual perception. The team found that L3 neurons, sensitive to brightness, are active in low-light conditions and play a crucial role in detecting sudden changes in luminance.

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For complex decisions, narrow them down to two

Psychologists from the University of Basel found that people focus their attention on the two most promising options when choosing between multiple alternatives. This leads to faster decisions and improved efficiency. The study's results propose a mathematical model describing dynamic interactions of preference formation and eye moveme...

Mouse brain region processes sound and motion at the same time

Researchers discovered that the inferior colliculus in mice integrates sound and movement information, allowing for rapid and accurate responses to external sounds. This integration helps prevent movement-related sounds from interfering with hearing, promoting survival.

Study sheds light on link between cannabis, anxiety and stress

Researchers at Vanderbilt University Medical Center found a molecule produced by the brain that reduces anxiety-causing connections between two brain regions. This discovery could lead to pharmacologic treatments regulating anxiety and depressive symptoms in people with stress-related anxiety disorders.

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Artificial intelligence as behavioral analyst

Researchers used high-speed cameras and computer algorithms to analyze the movements of larval zebrafish, identifying three distinct components of their prey capture behavior: orientation, approach, and capture. The study provides new insights into how the brain generates complex behaviors.

Blood pressure drug could help problem drinkers: QUT research

A study at Queensland University of Technology (QUT) suggests that pindolol, a blood pressure medication, can reduce anxiety-like behavior and neurogenic maladaptations in mice with long-term heavy alcohol consumption. The drug also restores damage caused by alcohol to new and immature neurons in the brain.

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Decision-making process becomes visible in the brain

Researchers have mapped zebrafish brain regions involved in decision making, revealing how sensory information is integrated to trigger a behavior. The study uses whole-brain imaging and behavioral paradigms to demonstrate the accumulation of evidence over time.

Neuroscientists develop models to identify internal states of the brain

Researchers at Princeton University have developed models to identify internal states of the brain in fruit flies. By analyzing song patterns and behavioral changes, they discovered three distinct strategies - Close, Chasing, and Whatever - linked to specific neurons controlling these shifts.

Deep learning to analyze neurological problems

A new study uses deep neural networks to accurately assess neurological disorders in rats and mice, identifying key features of motor impairments. This breakthrough technology has the potential to standardize diagnosis and monitoring of neurological disorders, enabling early interventions and improved patient outcomes.

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Brain biomarker predicts compulsive drinking

Researchers at Salk Institute discover a brain circuit controlling alcohol drinking behavior in mice, which can predict compulsive drinking. The study found that neural communication patterns between two brain regions are related to the development of compulsive drinking.

Walking changes vision

Research reveals that walking changes how we perceive our environment, especially in the peripheral visual field, which enhances processing for navigation. This shift in visual preference makes sense due to the role of peripheral input in tracking movement and direction.

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For the first time: A method for measuring animal personality

A study on mice has created a set of objective measurements for personality, revealing the connection between genes, behavior, and individual traits. The researchers found that each mouse had a unique personality that consistently informed its behavior.

Each mouse is different

Researchers create algorithm to identify stable traits that capture mouse behavior, revealing unique individual characteristics and genetic basis. The method has potential to advance knowledge of mouse personality and its relation to mental health and disease.

How meditation can help you make fewer mistakes

A new study from Michigan State University found that open monitoring meditation increased error recognition in non-meditators. The researchers measured brain activity using EEG and found a stronger neural signal about half a second after an error, indicating enhanced conscious error recognition.

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BARseq builds a better brain map

The researchers used BARseq to map the connections of 3,579 neurons in the auditory cortex of the mouse brain. This technology enables scientists to pinpoint the location of a neuron and determine its pattern of gene expression and physiological activity.

Research gauges neurodegeneration tied to FXTAS by measuring motor behavior

Researchers used a grip-force test to analyze sensorimotor function in people with the FMR1 premutation, identifying subtle symptoms and potential indicators of disease progression. The study aims to improve early diagnosis and treatment for Fragile X-associated tremor/ataxia syndrome (FXTAS) in at-risk individuals.

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Deep3DFly: the deep-learning way to design fly-like robots

Deep3DFly uses computer science and neuroscience to model fly movements and poses, enabling robots to climb challenging terrain. The system can automatically predict and correct errors in calculations, opening up new possibilities for robotics and medicine.

New method visualizes groups of neurons as they compute

Researchers have developed a fluorescent probe that can image electrical activity in multiple neurons simultaneously, enabling the visualization of brain circuits and their relation to behavior. This technique uses a voltage-sensing molecule to record electrical activity on a millisecond timescale, providing more informative measuremen...

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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

St. Jude neuroscientist Lindsay Schwarz receives a 2019 NIH Director's Award

Lindsay Schwarz, a St. Jude Children's Research Hospital neuroscientist, has won the prestigious NIH Director's New Innovator Award for her groundbreaking research on norepinephrine neurons and neural circuits. The award supports her innovative approaches to developing new molecular tools that target specific cell populations.

Depression and binge-drinking more common among military partners

A new study from King's College London found that depression and binge-drinking are more prevalent among female military partners than comparable women outside the military community. The research suggests that military partners may use binge-drinking as a coping mechanism for the stress and separation caused by deployment.

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Study finds hub linking movement and motivation in the brain

Researchers identify lateral septum as crucial link between circuits guiding goal-directed movement and motivated behavior. The study shows that the LS directly encodes information about speed and acceleration, enabling it to integrate or optimize performance across environmental signals.

Genetically tailored instruction improves songbird learning

Researchers at UCSF found that tailoring instruction to individual birds' genetic predispositions can improve their learning abilities. In contrast, standardized tutoring programs failed to engage birds from families with different song tempo preferences.

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