Research on the brain basis of behavior. Covers reward and pleasure signals, attention in children, taste circuitry, and adaptive AI models.
A computer brain circuit has identified a potential mechanism for impaired decision making in schizophrenia, linked to reduced activity of molecules called NDMA receptors. The model's results provide new insight that may inform future treatments for neuropsychiatric conditions.
A groundbreaking study mapping cavefish brains has identified large-scale differences in brain structure and function between surface fish and cavefish populations. The research reveals how these morphological changes relate to changes in behavior, including sleep loss, reduced social behaviors, and alterations in sensory processing.
Researchers pinpoint a specific protein and brain region responsible for dissociation, a phenomenon affecting up to 10% of the population. This discovery could lead to targeted therapies for conditions like PTSD and borderline personality disorder.
As the pandemic progressed, individuals' personal risk assessments led to increased protective behaviors like hand washing and social distancing. The study found that knowing one's own risk affected behavior more than concerns about others.
Researchers at the University of Zurich have discovered that the orbitofrontal cortex can reprogram neurons in sensory areas to enable flexible decision-making. This process involves a direct connection between the two regions, allowing for rapid adaptation to new situations.
Researchers demonstrate a new x-ray microscopy technique called x-ray holographic nano-tomography (XNH) that can image large volumes of brain tissue at high resolutions. This technique, combined with artificial intelligence-driven image analysis, enables the comprehensive cataloging of neurons and tracing of individual neurons from mus...
A groundbreaking international research network will study how animals use odor information to guide behavior, aiming to understand the brain's evolution and potential applications in robotics and disease research. The project, led by CU Boulder, will reverse-engineer how the brain interprets odors and activate motor circuits.
Researchers found that when flying alone, individual fruit flies freeze as a response to an imminent threat, but this behaviour changes in the presence of others. When other flies begin to move after the threat has passed, it signals safety and causes the freezing fly to exit its frozen state.
Researchers at the Champalimaud Centre for the Unknown have discovered that fruit flies freeze as a social cue of danger, but also resume movement when others start moving again, signaling safety. Group size plays a crucial role in this behavior, with smaller groups freezing less and larger groups showing a more complex response pattern.
Researchers at Marshall University found that green apple vape flavor enhances nicotine reward by promoting high-sensitivity nAChRs. This could lead to heightened drug-seeking behavior and addiction risk, particularly among adolescents.
A study by Matthew Smith and colleagues found that changes in brain activity are linked to shifts in internal states, impacting decision-making. The researchers' discovery could inform understanding of mental conditions like ADHD and improve BCI design.
A new study identifies a genetic switch in brain cells that can toggle between sex-specific states when necessary, challenging the idea of sex as a fixed property. This finding has implications for human biology, particularly in understanding sex-typical behaviors and their flexibility.
New research found prenatal depression alters child's brain connectivity, with weaker white matter connections linked to increased aggression and hyperactivity in male children. The study suggests a need for better prenatal care to recognize and treat prenatal depression.
Scientists selectively bred zebrafish to exhibit distinct personality traits, finding that brain activities soon changed and new brain regions were activated. The study suggests a rapid pace of personality trait changes and potential implications for human behavior.
Research in mice found that a common green apple vape flavor, farnesene, enhances nicotine reward and is also rewarding on its own. Farnesene partially activated nicotinic receptors and increased high-sensitivity receptors, potentially heightening reward and drug-seeking behavior.
Research by American Psychological Association reveals that children who experience trauma show signs of accelerated aging, including early puberty and cellular changes. The study suggests that these adaptations may have originated as survival mechanisms but can lead to health consequences later in life.
Research has found that the brains of humans, flies, and mice share similar mechanisms for brain development and function. This similarity can be interpreted in two ways: as evidence of a single ancestral brain or independent evolution of brain circuits. The study identified shared genetic regulatory mechanisms controlling brain area f...
Researchers are investigating the link between impaired brain hubs and mental health issues using cutting-edge methods. The study aims to understand how hub regions contribute to altered brain network function and behavior, potentially leading to better treatments for brain disorders.
A new study published in the Canadian Medical Association Journal found that 1 in 10 kindergarten children had undiagnosed vision problems. The study highlights the importance of adequate follow-up care to ensure successful vision screening programs.
Research by Welsh academics finds that patients with PTSD exhibit exaggerated pupil reactions to both threatening and positive images, suggesting a hyper-response to any arousing stimulus. This discovery may lead to the development of new therapy approaches using positive images.
Researchers developed a low-cost, customizable VR system to study animal behavior using freely moving small animals. The system, called PiVR, enables the delivery of virtual realities in real-time, allowing scientists to examine causal relationships between neural activity and specific behaviors.
Amber Alhadeff, a behavioral neurobiologist at Monell Chemical Senses Center, has been awarded a $225,000 Klingenstein-Simons Fellowship Award in Neurosciences to study the role of gut signals in hunger-related neurons. Her research aims to improve understanding of diet-related diseases such as obesity and type 2 diabetes.
A systematic review led by McMaster University found that electronic cognitive behavioral therapy is more effective than face-to-face sessions in treating depression. The study revealed no difference in patient satisfaction or function between the two methods.
Researchers at Virginia Tech have identified over 40 genes expressed in the vLGN and discovered six new neuron subtypes, each with unique molecules and clustered in tightly packed striped layers. The study provides a more precise tool kit to understand the function of the vLGN and its downstream connections.
A $2.5 million Simons Foundation grant is supporting an international collaboration of neuroscientists to develop new tools for studying brain control over behavior across species, from songbirds to rats. The project aims to create a framework for understanding motor agility in any species or behavior.
A study of mice in semi-natural settings reveals that oxytocin can increase aggressive behavior as well as friendliness, depending on the environment. The findings suggest a more nuanced view of oxytocin's effects and highlight the need for complex environments to translate research findings to human behavior.
A study by researchers at Nanjing University found that synaptic variability allows the nervous system to generate variable motor programs, enabling flexibility and adaptability. This mechanism is crucial for learning new activities and adjusting to changing environments.
Researchers found that early genetic restoration of the SHANK3 gene rescued behaviors associated with autism spectrum disorder, including social interaction and repetitive grooming. The study suggests that genetic intervention in SHANK3-related ASD may be most effective earlier in development.
Researchers at Harvard Medical School have identified a population of neurons in the hypothalamus that controls hibernation-like behavior in mice. Stimulating these neurons induces torpor, while blocking their activity disrupts natural torpor, offering insights into the neural mechanisms underlying this state.
A decades-long study found that youth programs can have lasting positive effects on both participants and their children. The program, Raising Healthy Children, demonstrated benefits in behavior problems, developmental delays, and cognitive maturity.
Researchers developed a novel unbiased strategy to identify activated neural inputs underlying specific behaviors. Using mouse models, they demonstrated the input specificity of their approach, tracing activated cell ensembles.
Research at Binghamton University found that female college students exhibit reduced academic interest and increased impulsive behaviors with high alcohol use. The study suggests gender-based differences in brain function and metabolism contribute to these findings.
A recent study published in the Journal of Neuroscience found that high estrogen levels may increase feelings of reward in response to alcohol in female mice. The research suggests that treatment for alcohol use disorder may be more effective if sex differences are considered.
Researchers analyzed child brain activity using fMRI to predict working memory abilities during development. The study found that brain network activity in the frontoparietal network was unique to working memory and reflected individual capabilities.
Researchers at Max-Planck-Gesellschaft have created a miniature microscope that can capture neural activity in all cortical layers of freely behaving rats. This breakthrough technology allows for continuous imaging of neuron populations, even during complex behaviors, providing insights into the brain's circuit dynamics.
A recent study published in Drug and Alcohol Dependence found sex-related differences in the effects of cannabis use on brain activity and subjective response. Neural activity primarily underlies response to cannabis cues, with no differences between male and female users, while female users exhibit more intense subjective craving.
A team of scientists developed an innovative method to study eye movements in mice, revealing two types of eye movement coupled to head movement: 'head tilt compensation' and 'saccade and fixate'. These findings validate using mice to study human brain disorders, including schizophrenia, Alzheimer's disease, and stroke.
Researchers describe four categories of self-nudging tools: reminders and prompts, framing decisions in a certain way, reducing accessibility of harmful options, and using social pressure. This behavioral science technique can help individuals negotiate internal conflicts and reach long-term goals.
Researchers from University of California, Davis, found that immune responses before pregnancy can predict behavioral deficits in offspring if the mother's immune system is activated during pregnancy. The study used a mouse model to identify baseline immunoreactivity as a predictor of resilience or susceptibility to immune activation.
Scientists discovered widespread synaptic changes in sea slugs that learn to reject non-food objects, offering insight into human learning's impact on the brain. The study found that synaptic modifications occur in concert across various brain areas.
A subset of retinal neurons sends inhibitory signals to the brain, affecting subconscious behaviors such as synchronizing circadian rhythms with light/dark cycles. This discovery sheds light on how eyes influence our behavior and vision in response to light intensity.
Researchers successfully combined rat spinal cords with tissue-engineered muscles, creating a biohybrid system that produces electrical activity causing contraction. This innovation could lead to breakthroughs in understanding diseases like Lou Gehrig's and developing new surgical training tools.
Researchers at the University of Virginia Health System have made a groundbreaking discovery suggesting that improper cellular cleanup during brain development may cause lifelong behavioral issues. This process, mediated by the AIM2 inflammasome, plays a critical role in ensuring proper brain assembly and function.
A recent study published in Alzheimer's & Dementia found a strong association between mild behavioral impairment (MBI) and amyloid plaque deposits in the brains of elderly individuals. MBI may potentially serve as an early indicator of Alzheimer's disease, allowing for earlier diagnosis and intervention.
Research suggests that individuals with autism spectrum disorder exhibit differences in attention regulation, which may be attributed to altered locus coeruleus activity. This study found that participants with autism displayed atypically smaller pupil dilations during a distraction task, indicating dysregulation in the brainstem.
Research in mice reveals that lactation temporarily changes how a mother's TIDA neurons regulate prolactin secretion, causing them to fire more frequently and out of rhythm. However, these changes are fully reversible after weaning, suggesting a unique adaptation to motherhood.
Researchers use physics and technology to track animal movement, revealing key findings on flock behavior, neural network tracking, and burrowing forces. By analyzing animal motion, scientists gain a deeper understanding of collective behavior and individual animal actions.
Researchers discovered the anterior lateral motor cortex plays a crucial role in integrating vast amounts of information to make decisions, surpassing previous understanding of its primary function. This finding highlights the brain's remarkable ability to adapt to context and informs scientists' larger understanding of brain function.
Researchers at McGill University have discovered at least nine directions of brain-gender variation using a unique dataset and machine learning algorithms. This finding has important consequences for promoting equity, diversity, and inclusion in Canada and beyond.
Researchers identify specific cortical area responsible for food addiction's loss of control over intake, linked to obesity and eating disorders. The study provides new insights into the neural mechanisms underlying addictive behavior in food, suggesting potential therapeutic targets.
Researchers at Johannes Gutenberg University discovered a mechanism employed by fruit flies to broaden our understanding of visual perception. The team found that L3 neurons, sensitive to brightness, are active in low-light conditions and play a crucial role in detecting sudden changes in luminance.
Psychologists from the University of Basel found that people focus their attention on the two most promising options when choosing between multiple alternatives. This leads to faster decisions and improved efficiency. The study's results propose a mathematical model describing dynamic interactions of preference formation and eye moveme...
A new study found that low-intensity exercise activates brain networks involved in cognitive control and attention processing, while high-intensity exercise primarily affects emotion processing. The results suggest a potential therapeutic strategy for neurological and psychiatric disorders.
Researchers discovered that the inferior colliculus in mice integrates sound and movement information, allowing for rapid and accurate responses to external sounds. This integration helps prevent movement-related sounds from interfering with hearing, promoting survival.
Researchers at Vanderbilt University Medical Center found a molecule produced by the brain that reduces anxiety-causing connections between two brain regions. This discovery could lead to pharmacologic treatments regulating anxiety and depressive symptoms in people with stress-related anxiety disorders.
Researchers used high-speed cameras and computer algorithms to analyze the movements of larval zebrafish, identifying three distinct components of their prey capture behavior: orientation, approach, and capture. The study provides new insights into how the brain generates complex behaviors.
Researchers found that mice's visual capability changes between day and night due to their internal clock, not eye changes. They used a maze experiment to study how the circadian rhythm influences behavior and nerve signals in the retina.
Researchers at UNC School of Medicine found that specific neurons in the CeA contribute to reward-like behaviors and alcohol drinking. By selectively lesioning or ablating these neurons, animals drank less alcohol without affecting anxiety-like behavior.
Researchers discovered that myokine Dpp, produced by skeletal muscle, regulates feeding behavior by modulating dopamine levels in the brain. This finding sheds new light on the mechanisms governing feeding behavior and has implications for understanding metabolic diseases.
A study at Queensland University of Technology (QUT) suggests that pindolol, a blood pressure medication, can reduce anxiety-like behavior and neurogenic maladaptations in mice with long-term heavy alcohol consumption. The drug also restores damage caused by alcohol to new and immature neurons in the brain.