Autism research focuses on understanding heterogeneity between individuals, with Prof Michael Lombardo's project testing stratification by functional skills. The goal is to isolate specific biological markers and treatment responses.
A new study found that sleep medications increase the risk of dementia in white adults. However, the relationship between sleep medications and dementia risk varies by medication type and socio-economic status. The study suggests that patients with poor sleep should consider alternative solutions before taking medications.
A recent study of 437 children reveals associations between infant screen use and electroencephalography markers with cognitive outcomes. The findings suggest that excessive screen time during infancy may contribute to impairments in executive function.
A Japanese study found that mandatory cognitive screening tests for older drivers led to a significant decrease in motor vehicle collisions. However, the policy also resulted in an increase in road injuries for pedestrians and cyclists, particularly among younger age subgroups.
A decade-long study found that a healthy lifestyle, including a healthy diet, regular exercise, and cognitive activity, slows memory decline in older adults. Participants with the APOE gene, associated with Alzheimer's disease, also experienced slower memory loss.
A new study by University of British Columbia researchers found that brief exposure to diesel exhaust causes decreased brain connectivity and may impair cognitive performance. The study's findings suggest a link between air pollution and altered brain network connectivity in humans.
Researchers found that patients diagnosed with behavioral-variant frontotemporal dementia may have a cerebrospinal fluid leak, which can be treated. The study discovered CSF-venous fistulas in nine patients, who had their symptoms reversed after surgical closure.
The Cognitive Neuroscience Society Conference in San Francisco will explore the nature of thinking and memory. Highlights include presentations on aging, neurotechnology, and learning.
Research published in the Journal of Epidemiology & Community Health found that daily moderate and vigorous physical activity is positively associated with mid-life brain power. However, replacing these activities with just 6-7 minutes of sedentary behavior negatively impacts cognitive performance. The study analyzed data from over 4,4...
SourceBMJ Group·JournalJournal of Epidemiology and Community Health·TypeObservational study·DateJan 23, 2023
A study published in Archives of Gerontology and Geriatrics found that exercising alone twice or more weekly decreased the risk of developing cognitive impairment by 15.1%, while those who exercised with others showed a 29.2% decrease. Regular social exercise may be beneficial for preventing age-related cognitive disorders.
Researchers found that orienteering can improve spatial navigation and memory in healthy adults, suggesting it could be a useful intervention to prevent cognitive decline. The sport's unique combination of physical exercise and navigational skills may stimulate parts of the brain that are no longer needed due to modern conveniences.
Researchers found that wildfire exposure led to difficulty in sensory interference processing and increased frontal cortex activity, similar to PTSD symptoms. Cognitive deficits persisted 6-12 months post-wildfire, highlighting the need for targeted interventions to address climate trauma.
A large Danish population study found that premature birth before 34 weeks is linked to lower scores in maths and language tests as a teenager. However, the researchers noted that cognitive outcomes are not predetermined at birth but are heavily influenced by social circumstances.
Researchers found altered cognitive function months after the Camp Fire, including increased activity in brain regions involved in cognitive control. Climate trauma may impair daily functioning and reduce wellbeing by weakening interference processing abilities.
A University of Kansas study found that SMART Recovery holds promise in addressing specific concerns of the LGBTQ population, but improvement is still needed. Participants appreciated being part of an LGBTQ-specific group, but faced challenges such as emotion regulation, coping with stigma, and recalling cognitive tools.
A new study by Italian neuroscientists found that blind and deaf individuals' brains possess an innate functional architecture for integrating sensory information. This suggests that brain architecture can develop independently from sensory experience, adding weight to the 'nature versus nurture' debate.
Researchers developed HippoCamera, a new smartphone app that significantly improves memory recall by boosting attention to daily events. Users record videos and audio descriptions of everyday experiences, which are then replayed to reinforce memory consolidation.
A Florida Atlantic University study found that urban noise exposure during development affects the color of songbirds' beaks, which influence social interactions and mate choice. Males developed less bright beak coloration, while females developed brighter orange coloration than untreated birds.
A landmark study found a strong genetic correlation between higher education and protective causal association with several gut disorders. The research reveals that better education reduces the risk of diseases such as Alzheimer's and inflammatory bowel disease (IBD).
A study by Plamen Nikolov and Shahadath Hossain found that access to retirement plans can lead to significant adverse effects on cognitive functioning among the elderly. The researchers discovered that pension benefits and retirement resulted in reduced cognitive performance, particularly among females.
Researchers found that neurons in the hippocampus represent space in a nonlinear hyperbolic geometry that grows outward exponentially with time spent exploring an environment. This discovery provides valuable methods for analyzing data on neurocognitive disorders involving learning and memory.
Researchers examined associations between APOE ε2 and ε4 alleles, polygenic profiles, and Alzheimer's disease biomarkers. They found links between ε4 alleles with plasma and CSF Aβ42 and CSF tau, as well as differences in associations with tau and Aβ42.
The INCOG 2.0 guidelines provide critical updates to address issues in cognitive rehabilitation after traumatic brain injury, including the use of telerehabilitation tools to promote clinical implementation. The guidelines aim to close the evidence-practice gap and improve outcomes for individuals with TBI.
A 16-year longitudinal study found associations between DNA methylation-based measures and neuropsychologically-validated cognitive decline in midlife. The results suggest that these measures may serve as biomarkers for a molecular aging mechanism, potentially identifying individuals at risk of cognitive impairment and dementia.
A new study has mapped the parts of the brain that support fluid intelligence, a key feature of human cognition. The research found that patients with damage to the right frontal regions performed poorly in tasks requiring problem-solving and reasoning.
A multidisciplinary team of researchers discovered hearing impairment in a novel preclinical model of autism spectrum disorder. The study highlights the importance of considering sensory organs and their interactions with the brain in understanding ASD.
Researchers at the University of Bonn discovered that people with chronic epilepsy may have impaired dendritic integration, leading to less specific place cell firing and reduced ability to distinguish familiar from unfamiliar places. Administering a sodium ion channel inhibitor improved memory in animal models.
A recent study suggests that stimulating the intersection of two particular brain networks correlated with better patient outcomes than stimulating nearby sites for patients with Alzheimer's disease. Cognitive improvement was associated with DBS to the direct interface between the fornix and bed nucleus of the stria terminalis.
A study followed over 7,000 Canadians for three years to find that being female, physically active, and not obese were key to maintaining excellent health. Factors such as high income and social support also played a crucial role in optimal aging.
A Northwestern University study found that as people age, their cerebrospinal fluid immune system becomes dysregulated, leading to cognitive impairment and neurodegeneration. The discovery provides a new clue to the process of neurodegeneration and may potentially be used to treat inflammation of the brain.
A new study has shed light on how the most commonly used ADHD medication, methylphenidate, works in the brain. The research found that methylphenidate increases dopamine levels in the nucleus accumbens and improves coordinated brain network activity, resulting in more stable sustained attention in children with ADHD.
SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeObservational study·DateDec 8, 2022
A recent study published in Molecular Psychiatry reveals a genetic link between attention-deficit/hyperactivity disorder (ADHD) and Alzheimer's disease in older adults. Researchers used a polygenic risk score to analyze the relationship between ADHD genetic predisposition and cognitive decline, finding a higher risk of developing Alzhe...
Researchers discovered that trauma changes brain mechanisms involved in learning and survival, such as the salience network. The study found that people with PTSD struggle to distinguish between safe and dangerous stimuli when emotions are involved.
A study published by Tufts University has found a link between higher levels of vitamin D in brain tissue and improved cognitive function in adults. The research, which analyzed brain tissue from over 200 participants, suggests that vitamin D may play a role in protecting the aging brain against diseases such as Alzheimer's.
Drs. Emilie T. Reas and Tara Tracy will lead transformative research in cognitive aging, focusing on blood-brain barrier dysfunction and the role of KIBRA protein in age-related memory loss. The awards aim to build a cadre of outstanding researchers to better understand and alleviate effects of age-related cognitive decline.
Scientists at Beth Israel Deaconess Medical Center discovered gene usage similarities between COVID-19 patients' brains and aging brains. This study suggests a link between severe COVID-19 and accelerated brain aging, with potential implications for neurological follow-up in recovered individuals.
Researchers found that the NIH Toolbox Cognition Battery is a promising option for measuring cognitive change in people with intellectual disability. The study shows that the test is sensitive to developmental changes in children, teens, and young adults, which can help guide effective interventions.
The study found that Charisma Virtual Social Training improved recognition of emotions, inference of social intentions, understanding of perspectives, and description of pro-social qualities in youth. The research demonstrated significant benefits regardless of delivery model or ASD diagnosis status.
Researchers have identified optimal blood tests to detect Alzheimer's disease at its earliest stages. The study found that phospho-tau217 is a reliable marker for monitoring disease progression and selecting individuals for novel trials.
Researchers at MIT have discovered that the adult brain contains millions of silent synapses, which may explain how the brain forms new memories without modifying existing connections. These inactive connections can be recruited to help form new memories when important new information is presented.
Researchers argue that cognitive transformations are crucial in understanding desistance from crime. Individuals' cognitive shifts, such as attitudes and intentions, serve as foundations for social development, including behavioral changes related to criminal behavior.
A Finnish study found that cumulative adverse psychosocial factors in childhood are associated with poorer learning and memory in midlife. Specifically, poor self-regulatory behavior and social adjustment in childhood linked to poorer learning ability and memory decades later.
A new Hikikomori Questionnaire has been developed to identify individuals with pathological social withdrawal at an earlier stage. The questionnaire evaluates socialization, isolation, and emotional support on a scale of 0-4, providing a tool for early detection and treatment of hikikomori.
A Cornell-led collaboration used machine learning to predict Alzheimer's progression in cognitively normal and mildly impaired individuals. The modeling showed that MRI scans are most informative for asymptomatic cases, while PET scans are more effective for those with mild cognitive impairment.
Researchers discovered that krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging. Krill oil increases neuronal resilience, promoting anti-oxidative stress and anti-inflammation, and abrogating multiple aging hallmarks.
Scientists at Texas A&M University found that transplanting intestinal epithelial stem cells can repair the gut and reduce inflammation, potentially preserving cognitive function after a stroke. The study suggests that targeting gut health may be key to developing more effective stroke therapies.
A new study explores how older adults plan for future changes, such as stopping driving or using firearms. The research found that reducing access to potentially dangerous situations should be prompted by declining ability, not age alone. Trusted messengers like family and clinicians can lead conversations around limiting access, and s...
A new MIT study found that children from lower socioeconomic backgrounds have distinct brain patterns linked to reading difficulties, differing from those of higher-SES students. The research suggests that tailored interventions may be necessary for different groups of children.
A new study explores how corporal punishment impacts neural systems, linking it to increased anxiety, depression, and altered brain activity. The research found that adolescents who experienced physical punishments showed a larger neural response to error and a blunted response to reward.
SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeExperimental study·DateNov 16, 2022
Children's brains exhibit rapid GABA boosts during learning sessions, allowing for efficient consolidation of new information. Adults' brains, on the other hand, struggle to stabilize learned knowledge due to reduced GABA levels, leading to slower learning rates.
Researcher William Thompson's winning essay explores how social interactions shape human cognitive algorithms, shedding light on the evolutionary process of cognition. His studies show that accumulated generational knowledge is essential for adapting to new situations.
A new study found that eligible older adults who participate in the Supplemental Nutrition Assistance Program (SNAP) have slower memory decline than those who do not participate. Researchers measured memory function every two years over 20 years and found that SNAP users had about two fewer years of cognitive aging over a 10-year period.
Researchers found that efficient brain networks may contribute to healthy memory performance in older adults, while postnatal stress and early life adversity can affect brain development. Studies also showed persistent effects of early childhood neglect on brain white matter into young adulthood.
A randomized controlled trial found that oral ENT-01 significantly improves constipation and possibly neurological symptoms in persons with Parkinson disease. The treatment is safe for up to 25 days, with a dose-dependent effect that persists beyond the treatment period.
A new study from the University of Ottawa reveals that morning types tend to have superior verbal ability, contrary to previous research suggesting that evening types have an advantage. The study found that accounting for factors like bedtime and age, morning individuals outperformed their evening counterparts in verbal intelligence.
Research suggests exercise-induced activation of peripheral systems, such as muscle, gut, and liver, may affect neural plasticity and cognitive health. Circulating cathepsin B (CTSB) and brain-derived neurotrophic factor (BNDF) have been found to possess robust neuroprotective effects.
Researchers at the University of Arizona Health Sciences found that morning blue light therapy improved sleep quality and reduced PTSD symptom severity in patients. The study's results suggest a potential non-invasive treatment approach for retaining benefits of therapy long after treatment ends.
A large study of over 5,800 tween children found that growing up in a socioeconomically disadvantaged household can have lasting effects on brain development, with different patterns of connections between brain regions observed. Parental education emerged as the most significant factor associated with variations in brain connections.
A new study published in NEJM Evidence found that crossword puzzle training significantly improved cognitive function and daily activities, reducing brain shrinkage in individuals with mild cognitive impairment. The findings suggest that engaging with familiar activities like crossword puzzles may be more effective than computerized co...
Researchers found that actors' brain activity suppressed when hearing their own name during performance, indicating potential impact of theatre training on human brain. The study also investigated interpersonal coordination between actors and found specific brain systems involved in social interactions.